NL168830C - PROCESS FOR PREPARING THERAPEUTIC PREPARATIONS AND PROCESS FOR PREPARING AMIDS SUITABLE FOR THESE - Google Patents

PROCESS FOR PREPARING THERAPEUTIC PREPARATIONS AND PROCESS FOR PREPARING AMIDS SUITABLE FOR THESE

Info

Publication number
NL168830C
NL168830C NLAANVRAGE7101697,A NL7101697A NL168830C NL 168830 C NL168830 C NL 168830C NL 7101697 A NL7101697 A NL 7101697A NL 168830 C NL168830 C NL 168830C
Authority
NL
Netherlands
Prior art keywords
preparing
amids
therapeutic preparations
preparing therapeutic
preparations
Prior art date
Application number
NLAANVRAGE7101697,A
Other languages
Dutch (nl)
Other versions
NL7101697A (en
NL168830B (en
Original Assignee
Ucb Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Sa filed Critical Ucb Sa
Publication of NL7101697A publication Critical patent/NL7101697A/xx
Publication of NL168830B publication Critical patent/NL168830B/en
Application granted granted Critical
Publication of NL168830C publication Critical patent/NL168830C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NLAANVRAGE7101697,A 1970-02-13 1971-02-09 PROCESS FOR PREPARING THERAPEUTIC PREPARATIONS AND PROCESS FOR PREPARING AMIDS SUITABLE FOR THESE NL168830C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB697870A GB1309692A (en) 1970-02-13 1970-02-13 N-substituted lactams

Publications (3)

Publication Number Publication Date
NL7101697A NL7101697A (en) 1971-08-17
NL168830B NL168830B (en) 1981-12-16
NL168830C true NL168830C (en) 1982-05-17

Family

ID=9824325

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7101697,A NL168830C (en) 1970-02-13 1971-02-09 PROCESS FOR PREPARING THERAPEUTIC PREPARATIONS AND PROCESS FOR PREPARING AMIDS SUITABLE FOR THESE

Country Status (15)

Country Link
JP (2) JPS535301B1 (en)
BE (1) BE762728R (en)
CH (1) CH530395A (en)
CS (2) CS167911B2 (en)
DE (1) DE2106418C2 (en)
DK (1) DK137451B (en)
ES (1) ES388135A2 (en)
FI (1) FI54916C (en)
FR (1) FR2081508B2 (en)
GB (1) GB1309692A (en)
MY (1) MY7400072A (en)
NL (1) NL168830C (en)
SU (2) SU508185A3 (en)
YU (2) YU34876B (en)
ZA (1) ZA71877B (en)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1045043B (en) * 1975-08-13 1980-04-21 Isf Spa PYROLIDINE DERIVATIVES
GB1583871A (en) * 1976-10-19 1981-02-04 Ucb Sa Anti-aggregants
BE864269A (en) * 1977-03-03 1978-06-16 Parke Davis & Co NEW N- (AMINOALKYL SUBSTITUTE) -2-OXO-1-PYRROLIDINE-ACETAMIDES AND METHODS FOR PRODUCING THEM
ATE27T1 (en) 1978-05-08 1981-04-15 Ucb Sa LACTAM-N-ACETIC ACIDS AND THEIR AMIDES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM
IT1141287B (en) * 1979-06-13 1986-10-01 Nattermann A & Cie PYROLIDIN ACIDS AMIDS- (2) -ON- (1) -ILALKYL-CARBOXYLS, PROCEDURE FOR THEIR PREPARATION AND MEDICINAL PRODUCTS CONTAINING THEM
FR2515179A1 (en) * 1981-07-24 1983-04-29 Hoffmann La Roche PYRROLIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, INTERMEDIATES FOR THEIR SYNTHESIS AND THEIR THERAPEUTIC APPLICATION
EP0089900B1 (en) * 1982-03-24 1985-12-27 Prodes S.A. New n-((2-oxo-1-pyrrolidinyl)acetyl)piperazines, the methods of producing such new compounds and their salts as well as pharmaceutical preparations for therapeutic use containing these compounds or salts
GB8412358D0 (en) * 1984-05-15 1984-06-20 Ucb Sa Pharmaceutical composition
GB8412357D0 (en) * 1984-05-15 1984-06-20 Ucb Sa Pharmaceutical composition
DE3420193A1 (en) * 1984-05-30 1985-12-05 Boehringer Ingelheim KG, 6507 Ingelheim NEW SUBSTITUTED PYRROLIDINONES, METHOD FOR THEIR PRODUCTION AND MEDICINAL PRODUCTS
US4804400A (en) * 1986-09-12 1989-02-14 Ciba-Geigy Corporation N-phenyl-maleimides and herbicidal and plant growth regulating methods of use thereof
GB8827389D0 (en) * 1988-11-23 1988-12-29 Ucb Sa Process for preparation of(s)alpha-ethyl-2-oxo-1-pyrrolidineacetamide
TW544311B (en) * 1998-08-06 2003-08-01 Daiichi Seiyaku Co Therapeutic or preventive agent for intractable epilepsies
GB0004297D0 (en) * 2000-02-23 2000-04-12 Ucb Sa 2-oxo-1 pyrrolidine derivatives process for preparing them and their uses
US6686477B2 (en) * 2000-09-29 2004-02-03 Eastman Chemical Company Highly enantiomerically pure lactam-substituted propanoic acid derivatives and methods of making and using same
WO2002094787A1 (en) * 2001-05-23 2002-11-28 Ucb, S.A. 2-oxo-piperidinyl- and 2-oxo-azepanyl alkanoic acid derivativ es for the treatment of epilepsy and other neurological disorders
IL160045A0 (en) 2001-08-10 2004-06-20 Ucb Sa Oxopyrrolidine compounds, preparation of said compounds and their use in the manufacturing of levetiracetam and analogues
PL370529A1 (en) * 2001-10-08 2005-05-30 Ucb, S.A. Use of 2-oxo-1-pyrrolidine derivatives for the preparation of a drug
CA2515090A1 (en) 2003-02-03 2004-08-19 Teva Pharmaceutical Industries Ltd Process for producing levetiracetam
ES2214147B1 (en) 2003-02-28 2005-10-01 Farma-Lepori S.A. PROCEDURE FOR OBTAINING AN ANTIEPILEPTIC AGENT.
CA2497062A1 (en) 2004-02-18 2005-08-18 Dr. Reddy's Laboratories Limited Preparation of amino acid amides
CA2488325C (en) 2004-11-22 2010-08-24 Apotex Pharmachem Inc. Improved process for the preparation of (s)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide and (r)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide
WO2006095362A1 (en) * 2005-03-10 2006-09-14 Rubamin Limited Process for preparing levetiracetam
AU2006254335A1 (en) 2005-06-01 2006-12-07 Ucb Pharma, S.A. 2-oxo-1-pyrrolidine derivatives and their therapeutic use on the central nervous system
EP2147911A1 (en) 2008-07-24 2010-01-27 ZaCh System S.p.A. Process for the preparation of levetiracetam
DK3260118T3 (en) 2008-10-16 2021-04-19 Univ Johns Hopkins PROCEDURES AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION
WO2010132693A2 (en) 2009-05-13 2010-11-18 Nektar Therapeutics Oligomer-containing pyrrolidine compounds
US7939676B2 (en) 2009-09-17 2011-05-10 Zach System S.P.A. Process for the preparation of levetiracetam
JP6082250B2 (en) 2010-02-09 2017-02-15 ザ・ジョンズ・ホプキンス・ユニバーシティー Methods and compositions for improving cognitive function
CA2891122C (en) 2012-11-14 2021-07-20 The Johns Hopkins University Methods and compositions for treating schizophrenia
CN105142623A (en) 2013-03-15 2015-12-09 艾吉因生物股份有限公司 Methods and compositions for improving cognitive function
WO2014144663A1 (en) 2013-03-15 2014-09-18 The Johns Hopkins University Methods and compositions for improving cognitive function
ME03518B (en) 2014-01-21 2020-04-20 Janssen Pharmaceutica Nv Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use
KR102502485B1 (en) 2014-01-21 2023-02-21 얀센 파마슈티카 엔.브이. Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use
CN104059010A (en) * 2014-06-12 2014-09-24 浙江华海药业股份有限公司 Preparation method of 2-(2-oxopyrrolidine-1-yl)-butyrate
CN106591179B (en) * 2016-12-05 2018-07-03 长兴制药股份有限公司 Methyl packing bacterium and its prepare the application on (S)-α-ethyl -2- oxygen -1- pyrrolidine acetic acid salt in selective fractionation
RU2663899C1 (en) * 2017-07-19 2018-08-13 Федеральное государственное унитарное предприятие "Государственный научный центр "Научно-исследовательский институт органических полупродуктов и красителей" Process for the preparation of 1-carbamoylmethyl-4-phenyl-2-pyrrolidone
US11384050B1 (en) 2021-02-03 2022-07-12 Vitaworks Ip, Llc Method for preparing levetiracetam and intermediates thereof
US20240132513A1 (en) 2022-08-19 2024-04-25 Agenebio, Inc. Benzazepine derivatives, compositions, and methods for treating cognitive impairment

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1039113A (en) * 1964-08-06 1966-08-17 Ucb Sa New n-substituted lactams

Also Published As

Publication number Publication date
JPS535301B1 (en) 1978-02-25
CH530395A (en) 1972-11-15
YU144578A (en) 1982-10-31
SU508185A3 (en) 1976-03-25
CS167912B2 (en) 1976-05-28
MY7400072A (en) 1974-12-31
DK137451B (en) 1978-03-06
FI54916B (en) 1978-12-29
BE762728R (en) 1971-08-10
FR2081508B2 (en) 1975-06-06
ES388135A2 (en) 1973-05-01
NL7101697A (en) 1971-08-17
CS167911B2 (en) 1976-05-28
YU30671A (en) 1979-10-31
ZA71877B (en) 1971-10-27
DE2106418C2 (en) 1983-12-22
JPS53130656A (en) 1978-11-14
DE2106418A1 (en) 1971-08-19
SU508186A3 (en) 1976-03-25
NL168830B (en) 1981-12-16
GB1309692A (en) 1973-03-14
DK137451C (en) 1978-07-24
FR2081508A2 (en) 1971-12-03
JPS5420491B2 (en) 1979-07-23
YU34876B (en) 1980-04-30
FI54916C (en) 1979-04-10

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Legal Events

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V1 Lapsed because of non-payment of the annual fee