FI54916B - FRAMEWORK FOR THERAPEUTIC TREATMENT OF NUTRITIONAL N-SUBSTITUTE 2-PYRROLIDONER - Google Patents

FRAMEWORK FOR THERAPEUTIC TREATMENT OF NUTRITIONAL N-SUBSTITUTE 2-PYRROLIDONER

Info

Publication number
FI54916B
FI54916B FI383/71A FI38371A FI54916B FI 54916 B FI54916 B FI 54916B FI 383/71 A FI383/71 A FI 383/71A FI 38371 A FI38371 A FI 38371A FI 54916 B FI54916 B FI 54916B
Authority
FI
Finland
Prior art keywords
pyrrolidoner
nutritional
substitute
framework
therapeutic treatment
Prior art date
Application number
FI383/71A
Other languages
Finnish (fi)
Other versions
FI54916C (en
Inventor
Joseph Honore Lucien M Strubbe
Raymond Armand Linz
Original Assignee
Ucb Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Sa filed Critical Ucb Sa
Publication of FI54916B publication Critical patent/FI54916B/en
Application granted granted Critical
Publication of FI54916C publication Critical patent/FI54916C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
FI383/71A 1970-02-13 1971-02-10 FRAMEWORK FOR THERAPEUTIC TREATMENT OF NUTRITIONAL N-SUBSTITUTE 2-PYRROLIDONER FI54916C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB697870A GB1309692A (en) 1970-02-13 1970-02-13 N-substituted lactams

Publications (2)

Publication Number Publication Date
FI54916B true FI54916B (en) 1978-12-29
FI54916C FI54916C (en) 1979-04-10

Family

ID=9824325

Family Applications (1)

Application Number Title Priority Date Filing Date
FI383/71A FI54916C (en) 1970-02-13 1971-02-10 FRAMEWORK FOR THERAPEUTIC TREATMENT OF NUTRITIONAL N-SUBSTITUTE 2-PYRROLIDONER

Country Status (15)

Country Link
JP (2) JPS535301B1 (en)
BE (1) BE762728R (en)
CH (1) CH530395A (en)
CS (2) CS167911B2 (en)
DE (1) DE2106418C2 (en)
DK (1) DK137451B (en)
ES (1) ES388135A2 (en)
FI (1) FI54916C (en)
FR (1) FR2081508B2 (en)
GB (1) GB1309692A (en)
MY (1) MY7400072A (en)
NL (1) NL168830C (en)
SU (2) SU508185A3 (en)
YU (2) YU34876B (en)
ZA (1) ZA71877B (en)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1045043B (en) * 1975-08-13 1980-04-21 Isf Spa PYROLIDINE DERIVATIVES
GB1583871A (en) * 1976-10-19 1981-02-04 Ucb Sa Anti-aggregants
BE864269A (en) * 1977-03-03 1978-06-16 Parke Davis & Co NEW N- (AMINOALKYL SUBSTITUTE) -2-OXO-1-PYRROLIDINE-ACETAMIDES AND METHODS FOR PRODUCING THEM
EP0005689B1 (en) * 1978-05-08 1981-03-18 U C B, S.A. Lactam-n-acetic acids, their amides, process for their preparation and therapeutic compositions containing them
IT1141287B (en) * 1979-06-13 1986-10-01 Nattermann A & Cie PYROLIDIN ACIDS AMIDS- (2) -ON- (1) -ILALKYL-CARBOXYLS, PROCEDURE FOR THEIR PREPARATION AND MEDICINAL PRODUCTS CONTAINING THEM
FR2515179A1 (en) * 1981-07-24 1983-04-29 Hoffmann La Roche PYRROLIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, INTERMEDIATES FOR THEIR SYNTHESIS AND THEIR THERAPEUTIC APPLICATION
DE3361609D1 (en) * 1982-03-24 1986-02-06 Prodes Sa New n-((2-oxo-1-pyrrolidinyl)acetyl)piperazines, the methods of producing such new compounds and their salts as well as pharmaceutical preparations for therapeutic use containing these compounds or salts
GB8412357D0 (en) * 1984-05-15 1984-06-20 Ucb Sa Pharmaceutical composition
GB8412358D0 (en) * 1984-05-15 1984-06-20 Ucb Sa Pharmaceutical composition
DE3420193A1 (en) * 1984-05-30 1985-12-05 Boehringer Ingelheim KG, 6507 Ingelheim NEW SUBSTITUTED PYRROLIDINONES, METHOD FOR THEIR PRODUCTION AND MEDICINAL PRODUCTS
US4804400A (en) * 1986-09-12 1989-02-14 Ciba-Geigy Corporation N-phenyl-maleimides and herbicidal and plant growth regulating methods of use thereof
GB8827389D0 (en) * 1988-11-23 1988-12-29 Ucb Sa Process for preparation of(s)alpha-ethyl-2-oxo-1-pyrrolidineacetamide
TW544311B (en) * 1998-08-06 2003-08-01 Daiichi Seiyaku Co Therapeutic or preventive agent for intractable epilepsies
GB0004297D0 (en) 2000-02-23 2000-04-12 Ucb Sa 2-oxo-1 pyrrolidine derivatives process for preparing them and their uses
US6686477B2 (en) 2000-09-29 2004-02-03 Eastman Chemical Company Highly enantiomerically pure lactam-substituted propanoic acid derivatives and methods of making and using same
WO2002094787A1 (en) 2001-05-23 2002-11-28 Ucb, S.A. 2-oxo-piperidinyl- and 2-oxo-azepanyl alkanoic acid derivativ es for the treatment of epilepsy and other neurological disorders
IL160045A0 (en) * 2001-08-10 2004-06-20 Ucb Sa Oxopyrrolidine compounds, preparation of said compounds and their use in the manufacturing of levetiracetam and analogues
JP4351909B2 (en) * 2001-10-08 2009-10-28 ユセベ ファルマ ソシエテ アノニム Use of 2-oxo-1-pyrrolidine derivatives for the preparation of a medicament
WO2004069796A2 (en) 2003-02-03 2004-08-19 Teva Pharmaceutical Industries Ltd. Process for producing levetiracetam
ES2214147B1 (en) * 2003-02-28 2005-10-01 Farma-Lepori S.A. PROCEDURE FOR OBTAINING AN ANTIEPILEPTIC AGENT.
US7531673B2 (en) 2004-02-18 2009-05-12 Dr. Reddy's Laboratories Limited Preparation of amino acid amides
CA2488325C (en) 2004-11-22 2010-08-24 Apotex Pharmachem Inc. Improved process for the preparation of (s)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide and (r)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide
EP1863761A1 (en) * 2005-03-10 2007-12-12 Rubamin Limited Process for preparing levetiracetam
JP2008542322A (en) 2005-06-01 2008-11-27 ユセベ ファルマ ソシエテ アノニム 2-Oxo-1-pyrrolidine derivatives
EP2147911A1 (en) 2008-07-24 2010-01-27 ZaCh System S.p.A. Process for the preparation of levetiracetam
EP3260118B1 (en) 2008-10-16 2021-03-24 The Johns Hopkins University Methods and compositions for improving cognitive function
US8785661B2 (en) 2009-05-13 2014-07-22 Nektar Therapeutics Oligome-containing pyrrolidine compounds
US7939676B2 (en) 2009-09-17 2011-05-10 Zach System S.P.A. Process for the preparation of levetiracetam
EA037187B1 (en) 2010-02-09 2021-02-17 Дзе Джонс Хопкинс Юниверсити Method and composition for treating a cognitive disorder
US10154988B2 (en) 2012-11-14 2018-12-18 The Johns Hopkins University Methods and compositions for treating schizophrenia
US11160785B2 (en) 2013-03-15 2021-11-02 Agenebio Inc. Methods and compositions for improving cognitive function
EP2968237A4 (en) 2013-03-15 2016-08-31 Univ Johns Hopkins Methods and compositions for improving cognitive function
DK3096790T3 (en) 2014-01-21 2019-10-07 Janssen Pharmaceutica Nv COMBINATIONS INCLUDING POSITIVE ALLOSTERIC MODULATORS OR ORTHOSTERIC AGONISTS OF METABOTROP GLUTAMATERG SUBTYPE 2 RECEPTOR AND APPLICATION OF THESE
UA127921C2 (en) 2014-01-21 2024-02-14 Янссен Фармацевтика Нв Combinations containing positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use
CN104059010A (en) * 2014-06-12 2014-09-24 浙江华海药业股份有限公司 Preparation method of 2-(2-oxopyrrolidine-1-yl)-butyrate
CN106591179B (en) * 2016-12-05 2018-07-03 长兴制药股份有限公司 Methyl packing bacterium and its prepare the application on (S)-α-ethyl -2- oxygen -1- pyrrolidine acetic acid salt in selective fractionation
RU2663899C1 (en) * 2017-07-19 2018-08-13 Федеральное государственное унитарное предприятие "Государственный научный центр "Научно-исследовательский институт органических полупродуктов и красителей" Process for the preparation of 1-carbamoylmethyl-4-phenyl-2-pyrrolidone
US11384050B1 (en) 2021-02-03 2022-07-12 Vitaworks Ip, Llc Method for preparing levetiracetam and intermediates thereof
WO2024039886A1 (en) 2022-08-19 2024-02-22 Agenebio, Inc. Benzazepine derivatives, compositions, and methods for treating cognitive impairment

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1039113A (en) * 1964-08-06 1966-08-17 Ucb Sa New n-substituted lactams

Also Published As

Publication number Publication date
DK137451C (en) 1978-07-24
MY7400072A (en) 1974-12-31
YU30671A (en) 1979-10-31
DE2106418C2 (en) 1983-12-22
SU508186A3 (en) 1976-03-25
CS167912B2 (en) 1976-05-28
NL168830B (en) 1981-12-16
JPS5420491B2 (en) 1979-07-23
DK137451B (en) 1978-03-06
FR2081508A2 (en) 1971-12-03
CH530395A (en) 1972-11-15
YU144578A (en) 1982-10-31
CS167911B2 (en) 1976-05-28
YU34876B (en) 1980-04-30
ES388135A2 (en) 1973-05-01
DE2106418A1 (en) 1971-08-19
JPS53130656A (en) 1978-11-14
FI54916C (en) 1979-04-10
FR2081508B2 (en) 1975-06-06
GB1309692A (en) 1973-03-14
JPS535301B1 (en) 1978-02-25
NL168830C (en) 1982-05-17
NL7101697A (en) 1971-08-17
BE762728R (en) 1971-08-10
ZA71877B (en) 1971-10-27
SU508185A3 (en) 1976-03-25

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