NL162363C - PROCESS FOR PREPARING A MEDICINAL PRODUCT WITH BETA-ENERGY-LOCKING EFFECT THAT A 1-PHENOXY-2-HYDROXY-3-ALKYLAMINOPROPEN DERIVATIVE AND / OR A PHARMACEUTICALLY ACCEPTABLE ACID STOCK PROCESS. PREPARATION OF THESE DERIVATIVES AND THEIR ACID ADDITION SALTS. - Google Patents

PROCESS FOR PREPARING A MEDICINAL PRODUCT WITH BETA-ENERGY-LOCKING EFFECT THAT A 1-PHENOXY-2-HYDROXY-3-ALKYLAMINOPROPEN DERIVATIVE AND / OR A PHARMACEUTICALLY ACCEPTABLE ACID STOCK PROCESS. PREPARATION OF THESE DERIVATIVES AND THEIR ACID ADDITION SALTS.

Info

Publication number
NL162363C
NL162363C NL7002414.A NL7002414A NL162363C NL 162363 C NL162363 C NL 162363C NL 7002414 A NL7002414 A NL 7002414A NL 162363 C NL162363 C NL 162363C
Authority
NL
Netherlands
Prior art keywords
alkylaminopropen
phenoxy
beta
hydroxy
derivative
Prior art date
Application number
NL7002414.A
Other languages
Dutch (nl)
Other versions
NL7002414A (en
NL162363B (en
Original Assignee
Ici Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB47048/69A external-priority patent/GB1285038A/en
Application filed by Ici Ltd filed Critical Ici Ltd
Publication of NL7002414A publication Critical patent/NL7002414A/xx
Publication of NL162363B publication Critical patent/NL162363B/en
Application granted granted Critical
Publication of NL162363C publication Critical patent/NL162363C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/24—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
    • C07C243/26—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C243/30—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton
    • C07C243/32—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/54—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/62—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/52—Unsaturated compounds containing hydroxy or O-metal groups a hydroxy or O-metal group being bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/56—Unsaturated compounds containing hydroxy or O-metal groups containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D263/06—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
NL7002414.A 1969-02-21 1970-02-20 PROCESS FOR PREPARING A MEDICINAL PRODUCT WITH BETA-ENERGY-LOCKING EFFECT THAT A 1-PHENOXY-2-HYDROXY-3-ALKYLAMINOPROPEN DERIVATIVE AND / OR A PHARMACEUTICALLY ACCEPTABLE ACID STOCK PROCESS. PREPARATION OF THESE DERIVATIVES AND THEIR ACID ADDITION SALTS. NL162363C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB47048/69A GB1285038A (en) 1969-02-21 1969-02-21 Alkanolamine derivatives
GB944569 1969-02-21

Publications (3)

Publication Number Publication Date
NL7002414A NL7002414A (en) 1970-08-25
NL162363B NL162363B (en) 1979-12-17
NL162363C true NL162363C (en) 1980-05-16

Family

ID=26242944

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7002414.A NL162363C (en) 1969-02-21 1970-02-20 PROCESS FOR PREPARING A MEDICINAL PRODUCT WITH BETA-ENERGY-LOCKING EFFECT THAT A 1-PHENOXY-2-HYDROXY-3-ALKYLAMINOPROPEN DERIVATIVE AND / OR A PHARMACEUTICALLY ACCEPTABLE ACID STOCK PROCESS. PREPARATION OF THESE DERIVATIVES AND THEIR ACID ADDITION SALTS.

Country Status (20)

Country Link
JP (2) JPS535287B1 (en)
AT (3) AT305249B (en)
BE (1) BE746107A (en)
CA (1) CA945172A (en)
CH (3) CH547257A (en)
CS (3) CS153069B2 (en)
DE (1) DE2007751C2 (en)
DK (1) DK135278B (en)
ES (1) ES376788A1 (en)
FI (1) FI53120C (en)
FR (1) FR2034561A1 (en)
IE (1) IE34003B1 (en)
IL (1) IL33931A (en)
KE (1) KE2582A (en)
NL (1) NL162363C (en)
NO (1) NO128653B (en)
PL (3) PL93998B1 (en)
SE (1) SE391517B (en)
SU (3) SU493062A3 (en)
YU (4) YU34275B (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1311521A (en) * 1970-02-13 1973-03-28 Ici Ltd Alkanolamine derivatives
DE2048838A1 (en) * 1970-10-05 1972-04-06 C H Boehnnger Sohn, 6507 Ingel heim New 1 phenoxy 2 hydroxy 3 hydroxyal kylaminopropane and process for their manufacture
FR2132570B1 (en) * 1971-04-09 1974-08-02 Lipha
GB1387630A (en) * 1971-05-07 1975-03-19 Ici Ltd Phenoxyalkanolamine derivatives
GB1433595A (en) * 1972-07-06 1976-04-28 Ici Ltd Alkanolamine derivatives
DE2623314C2 (en) * 1976-05-25 1984-08-02 Hoechst Ag, 6230 Frankfurt 1-aryloxy-2-hydroxy-3-aminopropanes, processes for their preparation and pharmaceuticals containing them
DE2818999A1 (en) * 1978-04-29 1979-11-15 Basf Ag AMINO DERIVATIVES OF 3-ALKYL-5- (2-HYDROXYSTYRYL) -ISOXAZOLES
DE2943405A1 (en) 1979-10-26 1981-05-07 Basf Ag, 6700 Ludwigshafen NEW AMINO DERIVATIVES OF 5- (2-HYDROXYSTYRYL) -ISOXAZOLE
US4593119A (en) * 1980-11-28 1986-06-03 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4387103A (en) * 1980-11-28 1983-06-07 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
JPS57105206U (en) * 1980-12-16 1982-06-29
DE3407695A1 (en) * 1984-03-02 1985-09-12 Röhm Pharma GmbH, 6108 Weiterstadt PTERIDINE COMPOUNDS WITH PHARMACEUTICAL EFFECTIVENESS
DE3500761A1 (en) * 1985-01-11 1986-09-04 SOUR "PODRAVKA" OOUR "BELUPO 2", Proizvodnja kozmetičkih preparata i lijekova, Koprivnica Process for the production of atenolol and its derivatives
US4971959A (en) * 1987-04-14 1990-11-20 Warner-Lambert Company Trisubstituted phenyl analogs having activity for congestive heart failure
WO1994013631A1 (en) * 1992-12-10 1994-06-23 Teikoku Chemical Industries Co., Ltd. Propionic acid derivative
CA2287920A1 (en) * 1997-04-30 1998-11-05 Eli Lilly And Company Intermediates and a process for preparing benzo¬b|thiophenes
JP5225574B2 (en) * 2006-11-09 2013-07-03 エムキュア ファーマシューティカルズ リミテッド Improved process for the preparation of beta-blocker compounds
US8552036B2 (en) 2009-01-12 2013-10-08 Hetero Research Foundation Polymorph of atazanavir sulfate

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1593762A1 (en) * 1967-02-06 1972-06-08 Boehringer Sohn Ingelheim Process for the preparation of new substituted 1-phenoxy-2-hydroxy-3-alkylaminopropanes

Also Published As

Publication number Publication date
DK135278B (en) 1977-03-28
IE34003L (en) 1970-08-21
FR2034561A1 (en) 1970-12-11
IL33931A0 (en) 1970-04-20
DK135278C (en) 1977-09-12
DE2007751A1 (en) 1970-09-10
FR2034561B1 (en) 1974-05-24
SU537626A3 (en) 1976-11-30
CS153064B2 (en) 1974-02-22
YU41070A (en) 1978-10-31
YU34278B (en) 1979-04-30
JPS5037182B1 (en) 1975-12-01
AT303005B (en) 1972-11-10
DE2007751C2 (en) 1983-12-15
PL87019B1 (en) 1976-06-30
PL77781B1 (en) 1975-04-30
CS153069B2 (en) 1974-02-22
YU193475A (en) 1978-10-31
CS153062B2 (en) 1974-02-22
SU482943A3 (en) 1975-08-30
AT305249B (en) 1973-02-12
NL7002414A (en) 1970-08-25
CA945172A (en) 1974-04-09
NL162363B (en) 1979-12-17
FI53120B (en) 1977-10-31
IE34003B1 (en) 1975-01-08
FI53120C (en) 1978-02-10
YU34279B (en) 1979-04-30
YU193675A (en) 1978-10-31
CH547257A (en) 1974-03-29
YU34275B (en) 1979-04-30
SU493062A3 (en) 1975-11-25
YU193375A (en) 1978-10-31
NO128653B (en) 1973-12-27
IL33931A (en) 1974-01-14
YU34281B (en) 1979-04-30
AT305244B (en) 1973-02-12
BE746107A (en) 1970-08-17
KE2582A (en) 1975-12-05
JPS535287B1 (en) 1978-02-25
ES376788A1 (en) 1972-09-16
SE391517B (en) 1977-02-21
PL93998B1 (en) 1977-07-30
CH561175A5 (en) 1975-04-30
CH553747A (en) 1974-09-13

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V4 Discontinued because of reaching the maximum lifetime of a patent