NI201900050A - Inhibidores de magl - Google Patents

Inhibidores de magl

Info

Publication number
NI201900050A
NI201900050A NI201900050A NI201900050A NI201900050A NI 201900050 A NI201900050 A NI 201900050A NI 201900050 A NI201900050 A NI 201900050A NI 201900050 A NI201900050 A NI 201900050A NI 201900050 A NI201900050 A NI 201900050A
Authority
NI
Nicaragua
Prior art keywords
magl inhibitors
compositions
magl
useful
compounds
Prior art date
Application number
NI201900050A
Other languages
English (en)
Spanish (es)
Inventor
A Grice Cheryl
J Buzard Daniel
S White Nicole
L Hertzog Donald
Original Assignee
Abide Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abide Therapeutics Inc filed Critical Abide Therapeutics Inc
Publication of NI201900050A publication Critical patent/NI201900050A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/205Radicals derived from carbonic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965Non-condensed pyrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/002Heterocyclic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05Isotopically modified compounds, e.g. labelled

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NI201900050A 2016-11-16 2019-05-16 Inhibidores de magl NI201900050A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662423095P 2016-11-16 2016-11-16

Publications (1)

Publication Number Publication Date
NI201900050A true NI201900050A (es) 2019-10-30

Family

ID=62107273

Family Applications (1)

Application Number Title Priority Date Filing Date
NI201900050A NI201900050A (es) 2016-11-16 2019-05-16 Inhibidores de magl

Country Status (27)

Country Link
US (1) US9981930B1 (US07794700-20100914-C00125.png)
EP (1) EP3541822B1 (US07794700-20100914-C00125.png)
JP (1) JP6987859B2 (US07794700-20100914-C00125.png)
KR (1) KR20190077087A (US07794700-20100914-C00125.png)
CN (1) CN110248947B (US07794700-20100914-C00125.png)
AR (1) AR110088A1 (US07794700-20100914-C00125.png)
AU (1) AU2017361250A1 (US07794700-20100914-C00125.png)
BR (1) BR112019009991A2 (US07794700-20100914-C00125.png)
CA (1) CA3043612A1 (US07794700-20100914-C00125.png)
CL (1) CL2019001335A1 (US07794700-20100914-C00125.png)
CO (1) CO2019005038A2 (US07794700-20100914-C00125.png)
CR (1) CR20190243A (US07794700-20100914-C00125.png)
DO (1) DOP2019000121A (US07794700-20100914-C00125.png)
EA (1) EA201991074A1 (US07794700-20100914-C00125.png)
EC (1) ECSP19035377A (US07794700-20100914-C00125.png)
ES (1) ES2908632T3 (US07794700-20100914-C00125.png)
IL (1) IL266550A (US07794700-20100914-C00125.png)
JO (1) JOP20190105A1 (US07794700-20100914-C00125.png)
MA (1) MA46860A (US07794700-20100914-C00125.png)
MX (1) MX2019005771A (US07794700-20100914-C00125.png)
NI (1) NI201900050A (US07794700-20100914-C00125.png)
PE (1) PE20191146A1 (US07794700-20100914-C00125.png)
PH (1) PH12019501102A1 (US07794700-20100914-C00125.png)
RU (1) RU2019116514A (US07794700-20100914-C00125.png)
TN (1) TN2019000150A1 (US07794700-20100914-C00125.png)
TW (1) TW201831458A (US07794700-20100914-C00125.png)
WO (1) WO2018093946A1 (US07794700-20100914-C00125.png)

Families Citing this family (12)

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SI2800565T1 (sl) 2012-01-06 2020-10-30 Lundbeck La Jolla Research Center, Inc. Karbamatne spojine in metode izdelave in uporabe le-teh
MX2017014344A (es) 2015-05-11 2018-04-11 Abide Therapeutics Inc Metodos para el tratamiento de la inflacion o el dolor neuropatico.
ES2892952T3 (es) 2016-09-19 2022-02-07 H Lundbeck As Carbamatos de piperazina como moduladores del MAGL y/o ABHD6 y su uso
JOP20190107A1 (ar) * 2016-11-16 2019-05-09 Lundbeck La Jolla Research Center Inc مثبطات أحادي أسيل جليسرول ليباز (magl)
JOP20190106A1 (ar) * 2016-11-16 2019-05-09 Lundbeck La Jolla Research Center Inc مثبطات أحادي أسيل جليسرول ليباز (magl)
CA3043609A1 (en) 2016-11-16 2018-05-24 Abide Therapeutics, Inc. Pharmaceutical formulations
AU2017361257B2 (en) 2016-11-16 2022-02-10 H. Lundbeck A/S. Crystalline forms of a MAGL inhibitor
BR112020004101A2 (pt) 2017-08-29 2020-09-24 Lundbeck La Jolla Research Center, Inc. compostos de espirociclo e métodos para produzir e usar os mesmos
BR112020008762A2 (pt) * 2017-11-02 2020-10-20 Aicuris Gmbh & Co. Kg indol-2-carboxamidas amino-tiazol substituídas altamente ativas inovadoras ativas contra o vírus da hepatite b (hbv)
EA202092586A1 (ru) 2018-05-15 2021-03-10 Лундбекк Ла-Хойя Рисерч Сентер, Инк. Ингибиторы magl
MX2022013224A (es) * 2020-04-21 2022-11-14 H Lundbeck As Sintesis de un inhibidor de la monoacilglicerol lipasa.
TW202229255A (zh) 2020-11-13 2022-08-01 丹麥商H 朗德貝克公司 Magl抑制劑

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JOP20190267A1 (ar) * 2017-05-23 2019-11-18 Lundbeck La Jolla Research Center Inc مثبطات بيرازول magl

Also Published As

Publication number Publication date
TN2019000150A1 (en) 2020-10-05
PH12019501102A1 (en) 2019-08-19
IL266550A (en) 2019-07-31
EP3541822A4 (en) 2020-04-29
MA46860A (fr) 2019-09-25
AU2017361250A1 (en) 2019-05-30
US20180134675A1 (en) 2018-05-17
CN110248947A (zh) 2019-09-17
CN110248947B (zh) 2022-04-01
BR112019009991A2 (pt) 2019-08-27
CL2019001335A1 (es) 2019-10-04
MX2019005771A (es) 2019-12-05
KR20190077087A (ko) 2019-07-02
EA201991074A1 (ru) 2019-12-30
CA3043612A1 (en) 2018-05-24
JP2020502047A (ja) 2020-01-23
AR110088A1 (es) 2019-02-20
US9981930B1 (en) 2018-05-29
CO2019005038A2 (es) 2019-05-31
DOP2019000121A (es) 2019-09-30
ECSP19035377A (es) 2019-05-31
EP3541822A1 (en) 2019-09-25
PE20191146A1 (es) 2019-09-02
JOP20190105A1 (ar) 2019-05-09
RU2019116514A (ru) 2020-12-17
CR20190243A (es) 2019-06-26
EP3541822B1 (en) 2022-01-19
ES2908632T3 (es) 2022-05-03
WO2018093946A1 (en) 2018-05-24
TW201831458A (zh) 2018-09-01
JP6987859B2 (ja) 2022-01-05

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