MY8700652A - Medicinal compositions comprising as an active ingredient substituted 1,4-benzoquinones - Google Patents

Medicinal compositions comprising as an active ingredient substituted 1,4-benzoquinones

Info

Publication number
MY8700652A
MY8700652A MY652/87A MY8700652A MY8700652A MY 8700652 A MY8700652 A MY 8700652A MY 652/87 A MY652/87 A MY 652/87A MY 8700652 A MY8700652 A MY 8700652A MY 8700652 A MY8700652 A MY 8700652A
Authority
MY
Malaysia
Prior art keywords
benzoquinones
active ingredient
medicinal compositions
substituted
ingredient substituted
Prior art date
Application number
MY652/87A
Other languages
English (en)
Inventor
Imada Isure
Nagaoka Akinobu
Hirata Minoru
Okutani Tetsuya
Goto Giichi
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of MY8700652A publication Critical patent/MY8700652A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C07C46/02—Preparation of quinones by oxidation giving rise to quinoid structures
    • C07C46/06—Preparation of quinones by oxidation giving rise to quinoid structures of at least one hydroxy group on a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C07C46/02—Preparation of quinones by oxidation giving rise to quinoid structures
    • C07C46/06—Preparation of quinones by oxidation giving rise to quinoid structures of at least one hydroxy group on a six-membered aromatic ring
    • C07C46/08—Preparation of quinones by oxidation giving rise to quinoid structures of at least one hydroxy group on a six-membered aromatic ring with molecular oxygen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
    • C07C50/28—Quinones containing groups having oxygen atoms singly bound to carbon atoms with monocyclic quinoid structure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
MY652/87A 1979-12-30 1987-12-30 Medicinal compositions comprising as an active ingredient substituted 1,4-benzoquinones MY8700652A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP17112579A JPS5697223A (en) 1979-12-30 1979-12-30 Tissue metabolism activator

Publications (1)

Publication Number Publication Date
MY8700652A true MY8700652A (en) 1987-12-31

Family

ID=15917438

Family Applications (1)

Application Number Title Priority Date Filing Date
MY652/87A MY8700652A (en) 1979-12-30 1987-12-30 Medicinal compositions comprising as an active ingredient substituted 1,4-benzoquinones

Country Status (9)

Country Link
US (1) US4436753A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0031727B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5697223A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE21031T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (2) DE3049039A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HK (1) HK64089A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1144075B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MY (1) MY8700652A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SG (1) SG84688G (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3069496D1 (de) * 1979-06-28 1984-11-29 Takeda Chemical Industries Ltd 2,3-dialkoxy-1,4-quinone derivatives; method of producing 1,4-quinone derivatives
JPS58174313A (ja) * 1982-04-06 1983-10-13 Takeda Chem Ind Ltd 動物組織の線維化抑制剤
US4808339A (en) * 1982-04-13 1989-02-28 Takeda Chemical Industries, Ltd. Benzoquinone derivatives
JPS58177934A (ja) * 1982-04-13 1983-10-18 Takeda Chem Ind Ltd ベンゾキノン誘導体
JPS59204167A (ja) * 1983-05-02 1984-11-19 Takeda Chem Ind Ltd ヒドロキノン誘導体およびその製法
JPS60130515A (ja) * 1983-12-15 1985-07-12 Shiratori Seiyaku Kk 血中２，３−ジホスホグリセリン酸上昇剤
JPS60255749A (ja) * 1984-05-31 1985-12-17 Univ Nagoya キノン誘導体
MX9203040A (es) * 1984-08-01 1992-07-31 Takeda Chemical Industries Ltd Derivados de quinona y composicion farmaceutica que los contiene.
EP0201196B1 (en) * 1985-04-08 1991-07-03 Takeda Chemical Industries, Ltd. Benzoquinone derivatives, their production and use
JP2503571B2 (ja) * 1988-02-26 1996-06-05 武田薬品工業株式会社 脳循環代謝改善剤
JPH08768B2 (ja) * 1989-08-24 1996-01-10 武田薬品工業株式会社 神経成長因子分泌誘導剤
RU1822549C (ru) * 1989-12-06 1996-08-20 Тихоокеанский институт биоорганической химии ДВО АН СССР Полигидрокси-1,4-нафтохиноны, обладающие свойством протектора миокарда при его ишемии и реперфузии
EP0560568A3 (en) * 1992-03-13 1994-06-29 Takeda Chemical Industries Ltd Hydroquinone derivatives and intermediates for production thereof
DK0643775T3 (da) * 1992-05-28 2004-09-06 Ct For Molecular Biology And M Quinonderivater til forbedring af cellebioenergi
EP0788793A1 (en) 1996-02-01 1997-08-13 Takeda Chemical Industries, Ltd. Idebenone for the treatment of dementia
AU8562998A (en) * 1997-08-12 1999-03-01 Takeda Chemical Industries Ltd. Idebenone-containing preparation for percutaneous administration
DE19932197A1 (de) 1999-07-09 2001-01-18 Neudecker Birgit Topisch anzuwendendes Mittel mit schützender und regenerativer Wirkung
US20050152857A1 (en) * 2004-01-08 2005-07-14 Pcr Technology Holdings, Lc Method and preparation for reducing sunburn cell formation in skin
US20050175559A1 (en) * 2004-02-10 2005-08-11 Pcr Technology Holdings, Lc Method and preparation for reducing skin hyperpigmentation
US20050197407A1 (en) * 2004-02-13 2005-09-08 Pcr Technology Holdings, Lc Method and preparation for reducing irritation and/or inflammatory reaction in human skin
CA2589252C (en) 2004-11-25 2012-12-04 Meiji Dairies Corporation Ameliorant for renal insufficiency
EP2564842A1 (en) 2005-06-01 2013-03-06 Edison Pharmaceuticals, Inc. Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers
ES2823728T3 (es) * 2005-09-15 2021-05-10 Ptc Therapeutics Inc Variantes de cola de agentes terapéuticos con actividad redox para el tratamiento de enfermedades mitocondriales y otras afecciones y la modulación de biomarcadores de energía
AR053665A1 (es) * 2006-01-23 2007-05-16 Creactivar S A Uso de la mimosina o un derivado de la misma, en el tratamiento de las manifestaciones cutaneas de la psoriasis y de los desordenes cutaneos relacionados con esta y una composicion cosmetica o farmaceutica que la comprende
US9278085B2 (en) 2006-02-22 2016-03-08 Edison Pharmaceuticals, Inc. Side-chain variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers
EP3827815B1 (en) 2008-09-10 2023-09-06 PTC Therapeutics, Inc. Treatment of pervasive developmental disorders with redox-active therapeutics
US20100129431A1 (en) * 2008-11-24 2010-05-27 Alpharx Inc. Idebenone composition for the treatment of neurological disorders
WO2011079212A2 (en) * 2009-12-24 2011-06-30 LifeSpan Extension, LLC Methods and compositions for identifying, producing and using plant-derived products modulating cell function and aging
US10017445B2 (en) 2012-07-12 2018-07-10 Concert Pharmaceuticals, Inc. Deuterated idebenone
WO2017106803A1 (en) 2015-12-17 2017-06-22 Bioelectron Technology Corporation Flouroalkyl, flouroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5919930B2 (ja) * 1974-05-02 1984-05-09 武田薬品工業株式会社 キノン酸誘導体の製造法
JPS51128932A (en) * 1975-04-30 1976-11-10 Takeda Chem Ind Ltd Organic compounds
DE3069496D1 (de) * 1979-06-28 1984-11-29 Takeda Chemical Industries Ltd 2,3-dialkoxy-1,4-quinone derivatives; method of producing 1,4-quinone derivatives

Also Published As

Publication number Publication date
EP0031727A2 (en) 1981-07-08
JPS5697223A (en) 1981-08-05
IT1144075B (it) 1986-10-29
ATE21031T1 (de) 1986-08-15
IT8050468A0 (it) 1980-12-24
DE3049039A1 (de) 1981-09-10
SG84688G (en) 1989-04-14
EP0031727B1 (en) 1986-07-30
EP0031727A3 (en) 1981-07-22
JPH0112727B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1989-03-02
DE3071684D1 (en) 1986-09-04
US4436753A (en) 1984-03-13
HK64089A (en) 1989-08-18

Similar Documents

Publication Publication Date Title
DE3071684D1 (en) Medicinal compositions comprising as an active ingredient substituted 1,4-benzoquinones
ES8702143A1 (es) Un procedimiento para preparar derivados de piperazina con actividad psicotropica
FR2356424A1 (fr) Compositions pharmaceutiques a base d'acide phophono-formique utiles pour lutter contre les infections virales
IE45256L (en) Quinazolone derivatives
FR2372219A1 (fr) Compositions anti-solaires
FR2446289A1 (fr) Compose de 2-penem, procede de preparation et composition pharmaceutique obtenue
NO855355L (no) Fremgangsmaate for fremstilling av naftalenderivater.
FR2361328A1 (fr) Nouvelles benzophenones utiles notamment a la preparation d'oximes et d'hydrazones
EG11259A (en) Preparation of pharmacologically active compounds as depresent for histamin recepters
IL38972A (en) Substituted phenyl alkanol derivatives,their preparation and compositions containing them
FR2386521A1 (fr) Interphenylene 8-aza-9-dioxathia-11,12-secoprostaglandines utiles comme medicaments
NO834884L (no) Fremgangsmaate for fremstilling av farmakologisk aktive nitroalifatiske forbindelser
FR2445330A1 (fr) Derives du 11-bromo-14,15-dioxo-e-homo-eburnane leur preparation et leur utilisation comme medicament
FR2361326A1 (fr) Derives de cyclohexane utiles comme agents odoriferants
ES8100249A1 (es) Un metodo para la preparacion de un compuesto de acido hi- droxamico
FR2376139A1 (fr) Nouveaux derives d'isoquinoleine-acetamide utiles comme medicaments
ES8502424A1 (es) Procedimiento para la preparacion de derivados de benzazepina
ES466867A1 (es) Procedimiento para la obtencion de 2,4-diclorofenil-imidazo-lil-etanonas y etanoles.
DK601483A (da) Benzhydrylpiperazinderivater
FR2398499A1 (fr) Nouvelles compositions pharmaceutiques a base de derives de l'imidazole pour inhiber la secretion de la prolactine
ES470462A1 (es) Procedimiento para producir imidazol-2-carbamatos
FR2384793A1 (fr) Nouveaux 7-halo-3,20-dioxo1,4-pregnadienes et 4-pregnenes, leur procede de preparation et compositions pharmaceutiques contenant lesdits composes
IE33893L (en) Insecticidal agents; substituted benzene derivatives
FR2398062A1 (fr) Aza-1 cyclododecatrienes-1,5,9 utilisables pour la preparation de matieres actives de produits phytosanitaires
ES453123A2 (es) Un procedimiento de preparacion de ciertos esteres del acidon-(2-carboxi-3,3,-dimetil-7-oxo-4-tio-lazabiciclo-(3,2,0)- hep-6-il)-2-fenil-malonamico.