MY8500351A - Pyridine derivatives as anti-inflammatory and immuno-regulatory agents - Google Patents

Pyridine derivatives as anti-inflammatory and immuno-regulatory agents

Info

Publication number
MY8500351A
MY8500351A MY351/85A MY8500351A MY8500351A MY 8500351 A MY8500351 A MY 8500351A MY 351/85 A MY351/85 A MY 351/85A MY 8500351 A MY8500351 A MY 8500351A MY 8500351 A MY8500351 A MY 8500351A
Authority
MY
Malaysia
Prior art keywords
immuno
inflammatory
pyridine derivatives
regulatory agents
regulatory
Prior art date
Application number
MY351/85A
Other languages
English (en)
Inventor
Joseph George Lombardino
Charles Armon Harbert
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of MY8500351A publication Critical patent/MY8500351A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/26—Radicals substituted by halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/32—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
MY351/85A 1981-06-26 1985-12-30 Pyridine derivatives as anti-inflammatory and immuno-regulatory agents MY8500351A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/276,242 US4371696A (en) 1980-07-14 1981-06-26 Certain pyridine methylthio acetaldehyde derivatives and non-cyclic and cyclic acetals thereof

Publications (1)

Publication Number Publication Date
MY8500351A true MY8500351A (en) 1985-12-31

Family

ID=23055809

Family Applications (1)

Application Number Title Priority Date Filing Date
MY351/85A MY8500351A (en) 1981-06-26 1985-12-30 Pyridine derivatives as anti-inflammatory and immuno-regulatory agents

Country Status (22)

Country Link
US (1) US4371696A (fr)
JP (1) JPS58916A (fr)
AU (1) AU528433B2 (fr)
BE (1) BE890374R (fr)
CH (1) CH648483A5 (fr)
DE (1) DE3215648A1 (fr)
FR (1) FR2508904B2 (fr)
GB (1) GB2100600B (fr)
GR (1) GR75753B (fr)
HK (1) HK67087A (fr)
IE (1) IE51727B1 (fr)
IL (1) IL63699A0 (fr)
IT (1) IT1200569B (fr)
KE (1) KE3458A (fr)
LU (1) LU83827A1 (fr)
MY (1) MY8500351A (fr)
NL (1) NL8105744A (fr)
NZ (1) NZ198215A (fr)
PH (1) PH17742A (fr)
SE (1) SE442110B (fr)
SG (1) SG56084G (fr)
ZA (1) ZA821139B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6179685U (fr) * 1984-10-26 1986-05-27
JPS61207304A (ja) * 1985-03-11 1986-09-13 Toyo Soda Mfg Co Ltd 農園芸用殺菌剤
JPH0445817Y2 (fr) * 1988-09-09 1992-10-28
US5610198A (en) * 1994-03-18 1997-03-11 The United States Of America As Represented By The Department Of Health And Human Services Anti-mycobacterial compositions and their use for the treatment of tuberculosis and related diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3558640A (en) * 1967-12-20 1971-01-26 Merck & Co Inc Certain pyridyl and thiazolyl methylthiopropionic acids and derivatives
GB1434271A (en) * 1972-09-28 1976-05-05 Squibb & Sons Inc Cephalosporins
US4246263A (en) * 1979-10-15 1981-01-20 Pfizer Inc. Antiinflammatory and immunoregulatory pyrimidines, their method of use and pharmaceutical compositions

Also Published As

Publication number Publication date
KE3458A (en) 1984-10-12
IE812748L (en) 1982-12-26
GB2100600A (en) 1983-01-06
NZ198215A (en) 1984-07-06
GB2100600B (en) 1983-09-14
LU83827A1 (fr) 1982-05-07
HK67087A (en) 1987-09-25
IL63699A0 (en) 1981-11-30
GR75753B (fr) 1984-08-02
US4371696A (en) 1983-02-01
ZA821139B (en) 1983-01-26
NL8105744A (nl) 1983-01-17
AU528433B2 (en) 1983-04-28
IE51727B1 (en) 1987-03-04
IT8219162A0 (it) 1982-01-18
CH648483A5 (fr) 1985-03-29
PH17742A (en) 1984-11-27
BE890374R (fr) 1982-03-16
SG56084G (en) 1985-03-08
JPS58916A (ja) 1983-01-06
FR2508904B2 (fr) 1985-11-29
IT1200569B (it) 1989-01-27
SE442110B (sv) 1985-12-02
SE8107101L (sv) 1982-12-27
FR2508904A2 (fr) 1983-01-07
DE3215648A1 (de) 1983-01-13

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