MY179987A - N-[4-(1h-pyrazolo[3,4-b]pyrazin-6-yl)-phenyl]-sulfonamides and their use as pharmaceuticals - Google Patents

N-[4-(1h-pyrazolo[3,4-b]pyrazin-6-yl)-phenyl]-sulfonamides and their use as pharmaceuticals

Info

Publication number
MY179987A
MY179987A MYPI2014000477A MYPI2014000477A MY179987A MY 179987 A MY179987 A MY 179987A MY PI2014000477 A MYPI2014000477 A MY PI2014000477A MY PI2014000477 A MYPI2014000477 A MY PI2014000477A MY 179987 A MY179987 A MY 179987A
Authority
MY
Malaysia
Prior art keywords
sgk
formula
activity
pyrazin
pyrazolo
Prior art date
Application number
MYPI2014000477A
Other languages
English (en)
Inventor
Nis Halland
Marc Nazare
Friedemann Schmidt
Tilo Weiss
Uwe Dietz
Armin Hofmeister
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of MY179987A publication Critical patent/MY179987A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
MYPI2014000477A 2011-09-19 2012-09-18 N-[4-(1h-pyrazolo[3,4-b]pyrazin-6-yl)-phenyl]-sulfonamides and their use as pharmaceuticals MY179987A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP11306179.0A EP2570415B1 (en) 2011-09-19 2011-09-19 N-[4-(1H-Pyrazolo[3,4-b]pyrazin-6-yl)-phenyl]-sulfonamides and their use as pharmaceuticals

Publications (1)

Publication Number Publication Date
MY179987A true MY179987A (en) 2020-11-19

Family

ID=46875813

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI2014000477A MY179987A (en) 2011-09-19 2012-09-18 N-[4-(1h-pyrazolo[3,4-b]pyrazin-6-yl)-phenyl]-sulfonamides and their use as pharmaceuticals

Country Status (17)

Country Link
US (1) US9174993B2 (zh)
EP (2) EP2570415B1 (zh)
AR (1) AR087907A1 (zh)
BR (1) BR112014006207A2 (zh)
CY (1) CY1117006T1 (zh)
DK (1) DK2570415T3 (zh)
EA (1) EA024295B1 (zh)
ES (2) ES2552836T3 (zh)
HR (1) HRP20151183T1 (zh)
HU (1) HUE026072T2 (zh)
MX (1) MX342869B (zh)
MY (1) MY179987A (zh)
PL (1) PL2570415T3 (zh)
PT (1) PT2570415E (zh)
SI (1) SI2570415T1 (zh)
TW (1) TWI577679B (zh)
WO (1) WO2013041502A1 (zh)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2017373758B2 (en) * 2016-12-07 2021-12-16 Orimos Therapeutics Co., Ltd. Compounds and pharmaceutical compositions for modulating SGK activity, and methods thereof
WO2018156401A1 (en) * 2017-02-24 2018-08-30 Indiana University Research And Technology Corporation Methods of inhibiting serum glucocorticoid induced kinase 1 (sgk1) as a treatment for salt and water balance diseases
US11530210B2 (en) 2019-06-14 2022-12-20 Janssen Pharmaceutica Nv Substituted heteroaromatic pyrazolo-pyridines and their use as GLUN2B receptor modulators
MX2021015500A (es) * 2019-06-14 2022-02-10 Janssen Pharmaceutica Nv Pirazolo-pirazinas sustituidas y su uso como moduladores del receptor glun2b.
US11459336B2 (en) 2019-06-14 2022-10-04 Janssen Pharmaceutica Nv Pyrazine carbamates and their use as GluN2B receptor modulators
CN113993868A (zh) 2019-06-14 2022-01-28 詹森药业有限公司 取代的吡唑并吡啶酰胺以及它们作为glun2b受体调节剂的用途
WO2020249799A1 (en) 2019-06-14 2020-12-17 Janssen Pharmaceutica Nv Pyridine carbamates and their use as glun2b receptor modulators
WO2024015055A1 (en) * 2022-07-13 2024-01-18 Thryv Therapeutics Inc. Pyrazolo[3,4-d]pyrimidin-6-yl-sulfonamide derivatives for the inhibition of sgk-1 and treatment of cancer
WO2024173323A1 (en) * 2023-02-14 2024-08-22 Bristol-Myers Squibb Company Amino-substituted pyrrolotriazine derivatives as inhibitors of sgk1

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6690240B2 (en) 2002-01-10 2004-02-10 Cirrus Logic, Inc. Low-jitter loop filter for a phase-locked loop system
US20050070542A1 (en) 2003-09-03 2005-03-31 Hodgetts Kevin J. 5-Aryl-pyrazolo[4,3-d]pyrimidines, pyridines, and pyrazines and related compounds
DE102004059781A1 (de) 2004-12-10 2006-06-22 Sanofi-Aventis Deutschland Gmbh Verwendung der Serum-/Glucocorticoid regulierten Kinase
DE102005015255A1 (de) 2005-04-04 2006-10-05 Merck Patent Gmbh Acylhydrazide
DE102006043443A1 (de) 2006-09-15 2008-03-27 Bayer Healthcare Ag Neue aza-bicyclische Verbindungen und ihre Verwendung
DE102007002717A1 (de) 2007-01-18 2008-07-24 Merck Patent Gmbh Heterocyclische Indazolderivate
KR20140064975A (ko) 2011-09-19 2014-05-28 사노피 Ｎ­［４­（１Ｈ­피라졸로［３，４­ｂ］피라진­６­일）­페닐］­설폰아미드 및 약제로서의 이의 용도
US20130072493A1 (en) 2011-09-19 2013-03-21 Sanofi N-[4-(1H-PYRAZOLO[3,4-b]PYRAZIN-6-YL)-PHENYL]-SULFONAMIDES AND THEIR USE AS PHARMACEUTICALS

Also Published As

Publication number Publication date
MX342869B (es) 2016-10-17
PL2570415T3 (pl) 2016-01-29
BR112014006207A2 (pt) 2017-04-11
WO2013041502A1 (en) 2013-03-28
PT2570415E (pt) 2015-11-23
EA024295B1 (ru) 2016-09-30
ES2552836T3 (es) 2015-12-02
SI2570415T1 (sl) 2015-12-31
US20140357640A1 (en) 2014-12-04
EA201490662A1 (ru) 2014-07-30
DK2570415T3 (en) 2015-11-23
EP2758399A1 (en) 2014-07-30
ES2659551T3 (es) 2018-03-16
US9174993B2 (en) 2015-11-03
HRP20151183T1 (hr) 2015-12-04
EP2570415A8 (en) 2013-05-22
TW201329079A (zh) 2013-07-16
EP2570415A1 (en) 2013-03-20
EP2758399B1 (en) 2017-11-15
AR087907A1 (es) 2014-04-23
HUE026072T2 (en) 2016-05-30
MX2014002736A (es) 2014-05-01
CY1117006T1 (el) 2017-04-05
TWI577679B (zh) 2017-04-11
EP2570415B1 (en) 2015-08-26

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