MY141935A - Improved process for the preparation of (ethoxymethyl)-tropan derivatives - Google Patents
Improved process for the preparation of (ethoxymethyl)-tropan derivativesInfo
- Publication number
- MY141935A MY141935A MYPI20050353A MYPI20050353A MY141935A MY 141935 A MY141935 A MY 141935A MY PI20050353 A MYPI20050353 A MY PI20050353A MY PI20050353 A MYPI20050353 A MY PI20050353A MY 141935 A MY141935 A MY 141935A
- Authority
- MY
- Malaysia
- Prior art keywords
- ethoxymethyl
- preparation
- improved process
- tropan
- derivatives
- Prior art date
Links
- OYQQNDQWHWJCNW-MNOVXSKESA-N (1S,5R)-1-(ethoxymethyl)-8-methyl-8-azabicyclo[3.2.1]octane Chemical class C(C)OC[C@]12CCC[C@H](CC1)N2C OYQQNDQWHWJCNW-MNOVXSKESA-N 0.000 title 1
- YTEQCFHEANIYBU-FHZGLPGMSA-N (1r,5r)-4-(ethoxymethyl)-8-methyl-8-azabicyclo[3.2.1]octane Chemical class C1CC(COCC)[C@@]2([H])CC[C@]1([H])N2C YTEQCFHEANIYBU-FHZGLPGMSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- RDHPKYGYEGBMSE-UHFFFAOYSA-N bromoethane Chemical compound CCBr RDHPKYGYEGBMSE-UHFFFAOYSA-N 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000003444 phase transfer catalyst Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102004004965A DE102004004965B4 (de) | 2004-01-31 | 2004-01-31 | Verfahren zur Herstellung eines 2-(Ethoxymethyl)-tropanderivates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY141935A true MY141935A (en) | 2010-07-30 |
Family
ID=34801391
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI20050353A MY141935A (en) | 2004-01-31 | 2005-01-28 | Improved process for the preparation of (ethoxymethyl)-tropan derivatives |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7544802B2 (enExample) |
| EP (1) | EP1713800B1 (enExample) |
| JP (1) | JP2007519660A (enExample) |
| CN (1) | CN1910180B (enExample) |
| AR (1) | AR047515A1 (enExample) |
| AT (1) | ATE449095T1 (enExample) |
| AU (1) | AU2005209382B2 (enExample) |
| CA (1) | CA2554125A1 (enExample) |
| DE (2) | DE102004004965B4 (enExample) |
| DK (1) | DK1713800T3 (enExample) |
| MY (1) | MY141935A (enExample) |
| NZ (1) | NZ548092A (enExample) |
| PE (1) | PE20050770A1 (enExample) |
| TW (1) | TWI338690B (enExample) |
| UY (1) | UY28730A1 (enExample) |
| WO (1) | WO2005073228A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9949964B2 (en) | 2016-09-07 | 2018-04-24 | Saniona A/S | Tesofensine compositions |
| CN115572289A (zh) * | 2022-10-24 | 2023-01-06 | 龙曦宁（上海）医药科技有限公司 | 一种特索芬辛的合成方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TR199801641T2 (xx) * | 1996-02-22 | 1998-11-23 | Neurosearch A/S | Tropan t�revleri bunlar�n haz�rlanmas� ve kullan�m� |
| JP2005508872A (ja) * | 2001-05-23 | 2005-04-07 | ニューロサーチ、アクティーゼルスカブ | トロパン誘導体及びこれをモノアミン神経伝達物質再取り込み阻害剤として使用する方法 |
| AU2002365288A1 (en) * | 2001-11-30 | 2003-06-10 | Neurosearch A/S | Tropane derivatives having dopamine reuptake inhibitor activity for the treatment of ischemic diseases |
| WO2021028011A1 (en) | 2019-08-09 | 2021-02-18 | Quintus Technologies Ab | System and method for handling and isostatic pressure treatment of a load |
-
2004
- 2004-01-31 DE DE102004004965A patent/DE102004004965B4/de not_active Expired - Fee Related
-
2005
- 2005-01-20 CA CA002554125A patent/CA2554125A1/en not_active Abandoned
- 2005-01-20 JP JP2006550028A patent/JP2007519660A/ja active Pending
- 2005-01-20 NZ NZ548092A patent/NZ548092A/xx unknown
- 2005-01-20 WO PCT/EP2005/000512 patent/WO2005073228A1/de not_active Ceased
- 2005-01-20 EP EP05701061A patent/EP1713800B1/de not_active Expired - Lifetime
- 2005-01-20 CN CN2005800027516A patent/CN1910180B/zh not_active Expired - Fee Related
- 2005-01-20 AT AT05701061T patent/ATE449095T1/de active
- 2005-01-20 AU AU2005209382A patent/AU2005209382B2/en not_active Expired - Fee Related
- 2005-01-20 DK DK05701061.3T patent/DK1713800T3/da active
- 2005-01-20 DE DE502005008535T patent/DE502005008535D1/de not_active Expired - Lifetime
- 2005-01-28 PE PE2005000107A patent/PE20050770A1/es not_active Application Discontinuation
- 2005-01-28 UY UY28730A patent/UY28730A1/es not_active Application Discontinuation
- 2005-01-28 TW TW094102759A patent/TWI338690B/zh active
- 2005-01-28 MY MYPI20050353A patent/MY141935A/en unknown
- 2005-01-28 AR ARP050100301A patent/AR047515A1/es unknown
- 2005-01-31 US US11/047,260 patent/US7544802B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2554125A1 (en) | 2005-08-11 |
| ATE449095T1 (de) | 2009-12-15 |
| CN1910180B (zh) | 2010-05-12 |
| US7544802B2 (en) | 2009-06-09 |
| DE102004004965A1 (de) | 2005-09-01 |
| AU2005209382A1 (en) | 2005-08-11 |
| DE502005008535D1 (de) | 2009-12-31 |
| TWI338690B (en) | 2011-03-11 |
| TW200538455A (en) | 2005-12-01 |
| AU2005209382B2 (en) | 2011-02-17 |
| HK1097845A1 (zh) | 2007-07-06 |
| CN1910180A (zh) | 2007-02-07 |
| EP1713800A2 (de) | 2006-10-25 |
| NZ548092A (en) | 2009-07-31 |
| EP1713800B1 (de) | 2009-11-18 |
| DE102004004965B4 (de) | 2006-01-05 |
| UY28730A1 (es) | 2005-09-30 |
| AR047515A1 (es) | 2006-01-25 |
| WO2005073228A1 (de) | 2005-08-11 |
| DK1713800T3 (da) | 2010-03-29 |
| JP2007519660A (ja) | 2007-07-19 |
| WO2005073228A8 (de) | 2005-10-27 |
| US20050171145A1 (en) | 2005-08-04 |
| PE20050770A1 (es) | 2005-11-10 |
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