MY137134A - Ptx3 gene expression suppressing method - Google Patents
Ptx3 gene expression suppressing methodInfo
- Publication number
- MY137134A MY137134A MYPI20031287A MYPI20031287A MY137134A MY 137134 A MY137134 A MY 137134A MY PI20031287 A MYPI20031287 A MY PI20031287A MY PI20031287 A MYPI20031287 A MY PI20031287A MY 137134 A MY137134 A MY 137134A
- Authority
- MY
- Malaysia
- Prior art keywords
- gene expression
- ptx3 gene
- suppressing method
- expression suppressing
- ptx3
- Prior art date
Links
- 230000014509 gene expression Effects 0.000 title abstract 3
- 101001082142 Homo sapiens Pentraxin-related protein PTX3 Proteins 0.000 abstract 2
- BFHAYPLBUQVNNJ-UHFFFAOYSA-N Pectenotoxin 3 Natural products OC1C(C)CCOC1(O)C1OC2C=CC(C)=CC(C)CC(C)(O3)CCC3C(O3)(O4)CCC3(C=O)CC4C(O3)C(=O)CC3(C)C(O)C(O3)CCC3(O3)CCCC3C(C)C(=O)OC2C1 BFHAYPLBUQVNNJ-UHFFFAOYSA-N 0.000 abstract 2
- 102100027351 Pentraxin-related protein PTX3 Human genes 0.000 abstract 2
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- YZCKVEUIGOORGS-UHFFFAOYSA-N Hydrogen atom Chemical group [H] YZCKVEUIGOORGS-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002596 lactones Chemical class 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Emergency Medicine (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37211402P | 2002-04-15 | 2002-04-15 | |
| US10/196,428 US20030195167A1 (en) | 2002-04-15 | 2002-07-17 | PTX3-gene expression inhibitor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY137134A true MY137134A (en) | 2008-12-31 |
Family
ID=28794074
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI20031287A MY137134A (en) | 2002-04-15 | 2003-04-08 | Ptx3 gene expression suppressing method |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20030195167A1 (enExample) |
| EP (1) | EP1494661B1 (enExample) |
| JP (1) | JP4409295B2 (enExample) |
| AT (1) | ATE445395T1 (enExample) |
| AU (1) | AU2003226456A1 (enExample) |
| DE (1) | DE60329668D1 (enExample) |
| MY (1) | MY137134A (enExample) |
| TW (1) | TWI349547B (enExample) |
| WO (1) | WO2003086380A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060276486A1 (en) * | 2003-04-17 | 2006-12-07 | Kowa Co., Ktd. | Lklf/klf2 gene expression promoter |
| WO2005053683A1 (en) * | 2003-11-26 | 2005-06-16 | Duke University | A method of preventing or treating glaucoma |
| ITRM20030596A1 (it) * | 2003-12-23 | 2005-06-24 | Sigma Tau Ind Farmaceuti | Uso di inibitori della pentraxina lunga ptx3, per la preparazione di un medicamento per la prevenzione e cura di patologie che rispondono all'inibizione dell'attivita' biologica di detta ptx3. |
| JP4667372B2 (ja) * | 2004-02-25 | 2011-04-13 | 株式会社ペルセウスプロテオミクス | 血管障害の程度の判定方法 |
| AU2005237543B2 (en) * | 2004-04-26 | 2011-02-10 | Alcon, Inc. | Statins for the treatment of ocular hypertension and glaucoma |
| WO2008001499A1 (en) * | 2006-06-29 | 2008-01-03 | Kowa Co., Ltd. | Prophylactic and/or therapeutic agent for rheumatoid arthritis |
| CN106950366B (zh) * | 2017-02-15 | 2019-03-22 | 中国医学科学院北京协和医院 | 一种acpa阴性的ra诊断标志物及其应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5244916A (en) * | 1992-01-31 | 1993-09-14 | The Scripps Research Institute | Inhibition of respiratory burst using posttranslational modification inhibitors |
| WO1999026657A1 (en) * | 1997-11-25 | 1999-06-03 | Musc Foundation For Research Development | Inhibitors of nitric oxide synthase |
| CA2365869A1 (en) * | 1999-03-08 | 2000-09-14 | Richard D. Tillyer | Crystalline hydrated dihydroxy open-acid simvastatin calcium salt |
| US6403637B1 (en) * | 1999-08-09 | 2002-06-11 | Univ Saint Louis | Methods of modulating matrix metalloproteinase activity and uses thereof |
| AU2001232245A1 (en) * | 2000-02-10 | 2001-08-20 | Takeda Chemical Industries Ltd. | Tnf- alpha inhibitors |
| US20020156122A1 (en) * | 2000-09-19 | 2002-10-24 | Novlmmune S.A. | Statins (HMG-CoA reductase inhibitors) as a novel type of immunomodulator, immunosuppressor and anti-inflammatory agent |
| US20020159974A1 (en) * | 2000-09-19 | 2002-10-31 | Francois Mach | Treatment of multiple sclerosis with statins (HMG-CoA reductase inhibitors) |
-
2002
- 2002-07-17 US US10/196,428 patent/US20030195167A1/en not_active Abandoned
-
2003
- 2003-04-08 MY MYPI20031287A patent/MY137134A/en unknown
- 2003-04-11 TW TW092108385A patent/TWI349547B/zh not_active IP Right Cessation
- 2003-04-11 AT AT03746454T patent/ATE445395T1/de not_active IP Right Cessation
- 2003-04-11 DE DE60329668T patent/DE60329668D1/de not_active Expired - Lifetime
- 2003-04-11 WO PCT/JP2003/004603 patent/WO2003086380A1/en not_active Ceased
- 2003-04-11 JP JP2003583400A patent/JP4409295B2/ja not_active Expired - Fee Related
- 2003-04-11 AU AU2003226456A patent/AU2003226456A1/en not_active Abandoned
- 2003-04-11 EP EP03746454A patent/EP1494661B1/en not_active Expired - Lifetime
-
2007
- 2007-03-30 US US11/694,288 patent/US20080161348A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1494661B1 (en) | 2009-10-14 |
| TW200403990A (en) | 2004-03-16 |
| JP4409295B2 (ja) | 2010-02-03 |
| JP2005522490A (ja) | 2005-07-28 |
| US20080161348A1 (en) | 2008-07-03 |
| ATE445395T1 (de) | 2009-10-15 |
| DE60329668D1 (de) | 2009-11-26 |
| AU2003226456A1 (en) | 2003-10-27 |
| US20030195167A1 (en) | 2003-10-16 |
| WO2003086380A1 (en) | 2003-10-23 |
| AU2003226456A8 (en) | 2003-10-27 |
| TWI349547B (en) | 2011-10-01 |
| EP1494661A1 (en) | 2005-01-12 |
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