MY102248A - Derivatives of 9-(2-hydroxyethoxymethyl) guanine - Google Patents

Derivatives of 9-(2-hydroxyethoxymethyl) guanine

Info

Publication number
MY102248A
MY102248A MYPI87002887A MYPI19872887A MY102248A MY 102248 A MY102248 A MY 102248A MY PI87002887 A MYPI87002887 A MY PI87002887A MY PI19872887 A MYPI19872887 A MY PI19872887A MY 102248 A MY102248 A MY 102248A
Authority
MY
Malaysia
Prior art keywords
hydroxyethoxymethyl
guanine
derivatives
group
ch2or3
Prior art date
Application number
MYPI87002887A
Other languages
English (en)
Inventor
Desire Alece Paul De Clercq Erik
Jean Henri Evarist Vander Haeghen Hubert
Honore Cornelius Busson Roger
Original Assignee
The Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Wellcome Foundation Ltd filed Critical The Wellcome Foundation Ltd
Publication of MY102248A publication Critical patent/MY102248A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
MYPI87002887A 1982-06-29 1987-10-09 Derivatives of 9-(2-hydroxyethoxymethyl) guanine MY102248A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL8202626A NL8202626A (nl) 1982-06-29 1982-06-29 Derivaten van 9-(2-hydroxyethoxymethyl)guanine.
EP83106299A EP0099493B1 (en) 1982-06-29 1983-06-28 Derivatives of 9-(2-hydroxyethoxymethyl)guanine

Publications (1)

Publication Number Publication Date
MY102248A true MY102248A (en) 1992-05-15

Family

ID=19839947

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI87002887A MY102248A (en) 1982-06-29 1987-10-09 Derivatives of 9-(2-hydroxyethoxymethyl) guanine

Country Status (13)

Country Link
US (1) US4548819A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0099493B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5910587A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE45580T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1208637A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3380410D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK159444C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI76087C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB2122618B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU189709B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL69095A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MY (1) MY102248A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL8202626A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8513460D0 (en) * 1985-05-29 1985-07-03 Glaxo Group Ltd Chemical compounds
AP55A (en) * 1987-08-15 1989-09-26 The Wellcome Foundation Ltd Therapeutic Acyclic Nucleosides
GB8719367D0 (en) * 1987-08-15 1987-09-23 Wellcome Found Therapeutic compounds
GB8725939D0 (en) * 1987-11-05 1987-12-09 Wellcome Found Therapeutic compounds
US4943579A (en) * 1987-10-06 1990-07-24 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Water soluble prodrugs of camptothecin
IT1223604B (it) * 1987-12-24 1990-09-29 Co Pharma Corp Srl Derivati purinici ad azione farmacologica
GB8800312D0 (en) * 1988-01-07 1988-02-10 Glaxo Group Ltd Process
DE68922903T2 (de) * 1988-12-19 1995-11-23 Wellcome Found Antivirale Pyrimidin- und Purinverbindungen, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate.
GB8829571D0 (en) * 1988-12-19 1989-02-08 Wellcome Found Antiviral compounds
GB8904855D0 (en) * 1989-03-03 1989-04-12 Beecham Group Plc Pharmaceutical treatment
US5451799A (en) * 1992-12-28 1995-09-19 Matsushita Electric Industrial Co., Ltd. MOS transistor for protection against electrostatic discharge
ES2157259T3 (es) * 1993-06-10 2001-08-16 Rolabo Sl Procedimiento para preparar esteres de aminoacidos y analogos de nucleosidos.
GB9320316D0 (en) * 1993-10-01 1993-11-17 Smithkline Beecham Plc Pharmaceuticals
TW282470B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1993-11-18 1996-08-01 Ajinomoto Kk
DE69513313T2 (de) * 1994-02-01 2000-07-13 Ajinomoto Co., Inc. Verfahren zur Herstellung von Nukleinsäurebasenderivaten
US5994361A (en) * 1994-06-22 1999-11-30 Biochem Pharma Substituted purinyl derivatives with immunomodulating activity
US5840891A (en) * 1994-07-28 1998-11-24 Syntex (U.S.A.) Inc. 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative
US5543414A (en) * 1994-07-28 1996-08-06 Syntex (Usa) Inc. Achiral amino acid acyl esters of ganciclovir and its derivatives
PE32296A1 (es) * 1994-07-28 1996-08-07 Hoffmann La Roche Ester de l-monovalina derivado de 2-(2-amino-1,6-dihidro-6-oxo-purin-9-il) metoxi-1,3-propandiol y sus sales farmaceuticamente aceptables
US6040446A (en) * 1996-01-26 2000-03-21 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative
US5840890A (en) * 1996-01-26 1998-11-24 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
US5756736A (en) * 1996-01-26 1998-05-26 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
AU1543797A (en) * 1996-01-26 1997-08-20 F. Hoffmann-La Roche Ag Process for preparing purine derivatives
US5700936A (en) * 1996-01-26 1997-12-23 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol valinate
US6703394B2 (en) 1996-02-16 2004-03-09 Medivir Ab Acyclic nucleoside derivatives
US5869493A (en) * 1996-02-16 1999-02-09 Medivir Ab Acyclic nucleoside derivatives
ZA9810490B (en) * 1997-12-03 1999-05-20 Dainippon Pharmaceutical Co 2-Aryl-8-oxodihydropurine derivative process for the preparation thereof pharmaceutical composition containing the same and intermediate therefor
CN100560073C (zh) 2001-12-14 2009-11-18 法玛塞特公司 用于治疗病毒感染的n4-酰基胞嘧啶核苷
US20070293517A1 (en) * 2004-06-09 2007-12-20 Ramot At Tel Aviv University Ltd. Derivatives Of Chemotherapeutic Agents With A Formaldehyde Releasing Moiety
US7846937B2 (en) * 2005-05-25 2010-12-07 Eli Lilly And Company Cyclopropanecarboxylate esters of acyclovir
CN115745997A (zh) * 2022-11-30 2023-03-07 湖北省宏源药业科技股份有限公司 一种高纯度伐昔洛韦杂质h制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1523865A (en) * 1974-09-02 1978-09-06 Wellcome Found Purine compunds and salts thereof
AU515553B2 (en) * 1976-03-01 1981-04-09 The Wellcome Foundation Limited Purine derivatives
JPS52105195A (en) * 1976-03-01 1977-09-03 Wellcome Found Substituted purine
US4060616A (en) * 1976-03-01 1977-11-29 Burroughs Wellcome Co. Purine derivatives with repeating unit

Also Published As

Publication number Publication date
US4548819A (en) 1985-10-22
DK297483D0 (da) 1983-06-28
DK297483A (da) 1983-12-30
DE3380410D1 (en) 1989-09-21
ATE45580T1 (de) 1989-09-15
FI76087B (fi) 1988-05-31
JPS5910587A (ja) 1984-01-20
JPH04990B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1992-01-09
FI832355L (fi) 1983-12-30
DK159444B (da) 1990-10-15
EP0099493B1 (en) 1989-08-16
HU189709B (en) 1986-07-28
IL69095A0 (en) 1983-10-31
CA1208637A (en) 1986-07-29
GB2122618A (en) 1984-01-18
FI832355A0 (fi) 1983-06-28
DK159444C (da) 1991-03-18
GB2122618B (en) 1985-11-13
FI76087C (fi) 1988-09-09
NL8202626A (nl) 1984-01-16
IL69095A (en) 1985-11-29
EP0099493A1 (en) 1984-02-01
GB8317504D0 (en) 1983-08-03

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