MXPA06013124A - Vectores de alfavirus derivados de tc-83, particulas y metodos. - Google Patents

Vectores de alfavirus derivados de tc-83, particulas y metodos.

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Publication number
MXPA06013124A
MXPA06013124A MXPA06013124A MXPA06013124A MXPA06013124A MX PA06013124 A MXPA06013124 A MX PA06013124A MX PA06013124 A MXPA06013124 A MX PA06013124A MX PA06013124 A MXPA06013124 A MX PA06013124A MX PA06013124 A MXPA06013124 A MX PA06013124A
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Mexico
Prior art keywords
particles
derived
methods
alphavirus vectors
arps
Prior art date
Application number
MXPA06013124A
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English (en)
Inventor
Jon O Rayner
Jonathan F Smith
Bolyn Hubby
Elizabeth A Reap
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Alphavax Inc
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Publication date
Application filed by Alphavax Inc filed Critical Alphavax Inc
Publication of MXPA06013124A publication Critical patent/MXPA06013124A/es

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    • C12N2770/36011—Togaviridae
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    • C12N2770/36011—Togaviridae
    • C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
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    • C12N2770/00011—Details
    • C12N2770/36011—Togaviridae
    • C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
    • C12N2770/36151—Methods of production or purification of viral material
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    • C12N2770/00011—Details
    • C12N2770/36011—Togaviridae
    • C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
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    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
    • C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES

Abstract

La presente descripcion proporciona replicones derivados de TC-83 VEE, particulas del replicon alfaviral y composiciones inmunogenicas que contienen las particulas del replicon alfaviral TC-83 que dirigen la expresion de al menos un antigeno cuando son introducidas en una celula hospedera adecuada. Las ARPs derivadas de TC-83, descritas aqui, son mejoradas porque las mismas son sometidas a una respuesta inmune especifica para el vector, inferior, que las ARPs del arte previo.
MXPA06013124A 2004-05-18 2005-05-18 Vectores de alfavirus derivados de tc-83, particulas y metodos. MXPA06013124A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57221204P 2004-05-18 2004-05-18
PCT/US2005/017766 WO2005113782A1 (en) 2004-05-18 2005-05-18 Tc-83-derived alphavirus vectors, particles and methods

Publications (1)

Publication Number Publication Date
MXPA06013124A true MXPA06013124A (es) 2007-05-23

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MXPA06013124A MXPA06013124A (es) 2004-05-18 2005-05-18 Vectores de alfavirus derivados de tc-83, particulas y metodos.

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US (5) US20050266550A1 (es)
EP (1) EP1751289B1 (es)
JP (1) JP5065024B2 (es)
CN (1) CN1989250B (es)
AT (1) ATE420965T1 (es)
AU (1) AU2005245956B2 (es)
CA (1) CA2567254C (es)
DE (1) DE602005012382D1 (es)
DK (1) DK1751289T3 (es)
ES (1) ES2321212T3 (es)
IL (1) IL178917A (es)
MX (1) MXPA06013124A (es)
NZ (1) NZ550818A (es)
PT (1) PT1751289E (es)
WO (1) WO2005113782A1 (es)
ZA (1) ZA200610561B (es)

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