MXPA06000915A - Inhibidores de quinasa p-38. - Google Patents

Inhibidores de quinasa p-38.

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Publication number
MXPA06000915A
MXPA06000915A MXPA06000915A MXPA06000915A MXPA06000915A MX PA06000915 A MXPA06000915 A MX PA06000915A MX PA06000915 A MXPA06000915 A MX PA06000915A MX PA06000915 A MXPA06000915 A MX PA06000915A MX PA06000915 A MXPA06000915 A MX PA06000915A
Authority
MX
Mexico
Prior art keywords
kinase inhibitors
kinase
p38beta
p38alpha
ameliorating
Prior art date
Application number
MXPA06000915A
Other languages
English (en)
Inventor
Yunfeng Fang
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MXPA06000915A publication Critical patent/MXPA06000915A/es

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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
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    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

Se proporcionan compuestos y composiciones para modular la actividad de las quinasas p38, incluyendo las quinasas p38a y p38??. Tambien se proporcionan metodos para tratar, prevenir, o aminorar uno o mas sintomas de una enfermedad o trastorno mediado por la quinasa p38.
MXPA06000915A 2003-07-25 2004-07-23 Inhibidores de quinasa p-38. MXPA06000915A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49009603P 2003-07-25 2003-07-25
PCT/US2004/023726 WO2005012241A2 (en) 2003-07-25 2004-07-23 p-38 KINASE INHIBITORS

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MXPA06000915A true MXPA06000915A (es) 2006-03-30

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EP (3) EP1687284B1 (es)
JP (1) JP2007500129A (es)
CN (2) CN100447137C (es)
AT (2) ATE482205T1 (es)
AU (2) AU2004261589B2 (es)
BR (1) BRPI0412918A (es)
CA (1) CA2534990A1 (es)
DE (2) DE602004029293D1 (es)
ES (1) ES2315703T3 (es)
MX (1) MXPA06000915A (es)
PL (1) PL1687284T3 (es)
PT (1) PT1687284E (es)
WO (1) WO2005012241A2 (es)

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CN100447137C (zh) 2008-12-31
US20100234404A1 (en) 2010-09-16
JP2007500129A (ja) 2007-01-11
EP1990338B1 (en) 2010-09-22
CN101337944A (zh) 2009-01-07
EP1687284B1 (en) 2008-10-29
WO2005012241A2 (en) 2005-02-10
DE602004029293D1 (de) 2010-11-04
EP1990338A3 (en) 2009-01-21
US20070111999A1 (en) 2007-05-17
PL1687284T3 (pl) 2009-04-30
ATE482205T1 (de) 2010-10-15
ES2315703T3 (es) 2009-04-01
AU2004261589A1 (en) 2005-02-10
AU2008202641A1 (en) 2008-07-03
CA2534990A1 (en) 2005-02-10
PT1687284E (pt) 2009-01-30
AU2004261589B2 (en) 2008-05-22
ATE412642T1 (de) 2008-11-15
WO2005012241A3 (en) 2005-04-14
CN1856480A (zh) 2006-11-01
BRPI0412918A (pt) 2006-09-26
EP1687284A2 (en) 2006-08-09
US7754726B2 (en) 2010-07-13
DE602004017494D1 (de) 2008-12-11
US20050020590A1 (en) 2005-01-27
US7700622B2 (en) 2010-04-20
EP1990338A2 (en) 2008-11-12

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