MXPA05006573A - Metodos para el tratamiento de dolor y dano traumatico usando benzamidas y composiciones que las contienen. - Google Patents

Metodos para el tratamiento de dolor y dano traumatico usando benzamidas y composiciones que las contienen.

Info

Publication number
MXPA05006573A
MXPA05006573A MXPA05006573A MXPA05006573A MXPA05006573A MX PA05006573 A MXPA05006573 A MX PA05006573A MX PA05006573 A MXPA05006573 A MX PA05006573A MX PA05006573 A MXPA05006573 A MX PA05006573A MX PA05006573 A MXPA05006573 A MX PA05006573A
Authority
MX
Mexico
Prior art keywords
methods
pain
benzamides
alkyl
treatment
Prior art date
Application number
MXPA05006573A
Other languages
English (en)
Inventor
Tito Serafini
Original Assignee
Renovis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Renovis Inc filed Critical Renovis Inc
Publication of MXPA05006573A publication Critical patent/MXPA05006573A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Abstract

Se describen metodos para el tratamiento y prevencion del dolor tal como el dolor neuropatico, y lesiones traumaticas tales como la lesion traumatica del cerebro y lesion aguda de la medula espinal, que comprende la administracion de cantidades efectivas de un compuesto benzamida de formula I: (ver formula (I)), (I) donde n es 1 o 2, R1 es un grupo seleccionado de acetilo, alquilo, amino, acilamino (NHCOR3), halo, nitro y trifluoroalquilo, R2 es alquilo saturado de 3 a 5 atomos, y R3 es alquilo de 1 a 5 atomos; se describen composiciones farmaceuticas, formas de dosificacion y metodos de administracion.
MXPA05006573A 2002-12-16 2003-12-16 Metodos para el tratamiento de dolor y dano traumatico usando benzamidas y composiciones que las contienen. MXPA05006573A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US43402202P 2002-12-16 2002-12-16
US10/736,460 US20040167226A1 (en) 2002-12-16 2003-12-15 Methods for the treatment of pain and traumatic injury using benzamides and compositions containing the same
PCT/US2003/039895 WO2004060286A2 (en) 2002-12-16 2003-12-16 Methods for the treatment of pain and traumatic injury using benzamides and compositions containing the same

Publications (1)

Publication Number Publication Date
MXPA05006573A true MXPA05006573A (es) 2006-02-22

Family

ID=32717767

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05006573A MXPA05006573A (es) 2002-12-16 2003-12-16 Metodos para el tratamiento de dolor y dano traumatico usando benzamidas y composiciones que las contienen.

Country Status (7)

Country Link
US (1) US20040167226A1 (es)
EP (1) EP1581202A2 (es)
JP (1) JP2006514056A (es)
AU (1) AU2003300939A1 (es)
CA (1) CA2510042A1 (es)
MX (1) MXPA05006573A (es)
WO (1) WO2004060286A2 (es)

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Also Published As

Publication number Publication date
AU2003300939A1 (en) 2004-07-29
AU2003300939A8 (en) 2004-07-29
EP1581202A2 (en) 2005-10-05
WO2004060286A3 (en) 2004-11-04
CA2510042A1 (en) 2004-07-22
US20040167226A1 (en) 2004-08-26
WO2004060286A2 (en) 2004-07-22
JP2006514056A (ja) 2006-04-27

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