MXPA05001458A - Combinacion de zd6474, un inhibidor del receptor del factor de crecimiento endotelial vascular, con radioterapia en tratamiento de cancer. - Google Patents
Combinacion de zd6474, un inhibidor del receptor del factor de crecimiento endotelial vascular, con radioterapia en tratamiento de cancer.Info
- Publication number
- MXPA05001458A MXPA05001458A MXPA05001458A MXPA05001458A MXPA05001458A MX PA05001458 A MXPA05001458 A MX PA05001458A MX PA05001458 A MXPA05001458 A MX PA05001458A MX PA05001458 A MXPA05001458 A MX PA05001458A MX PA05001458 A MXPA05001458 A MX PA05001458A
- Authority
- MX
- Mexico
- Prior art keywords
- treatment
- mmol
- methoxy
- cancer
- ylmethoxy
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
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| GB0218525A GB0218525D0 (en) | 2002-08-09 | 2002-08-09 | Combination therapy |
| GB0307560A GB0307560D0 (en) | 2003-04-02 | 2003-04-02 | Combination therapy |
| PCT/GB2003/003388 WO2004014383A1 (en) | 2002-08-09 | 2003-08-05 | Combination of zd6474, an inhibitor of the vascular endothelial growth factor receptor, with radiotherapy in the treatment of cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA05001458A true MXPA05001458A (es) | 2005-06-06 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA05001458A MXPA05001458A (es) | 2002-08-09 | 2003-08-05 | Combinacion de zd6474, un inhibidor del receptor del factor de crecimiento endotelial vascular, con radioterapia en tratamiento de cancer. |
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| EP (1) | EP1534287A1 (enExample) |
| JP (1) | JP2006502132A (enExample) |
| KR (1) | KR20050056190A (enExample) |
| CN (1) | CN1313094C (enExample) |
| AU (1) | AU2003249000B2 (enExample) |
| BR (1) | BR0313116A (enExample) |
| CA (1) | CA2495487A1 (enExample) |
| IL (1) | IL166522A0 (enExample) |
| MX (1) | MXPA05001458A (enExample) |
| NO (1) | NO20050450L (enExample) |
| NZ (1) | NZ537753A (enExample) |
| WO (1) | WO2004014383A1 (enExample) |
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| EE05330B1 (et) | 1999-11-05 | 2010-08-16 | Astrazeneca Ab | Kinasoliini derivaadid kui VEGF-i inhibiitorid |
| GB0008269D0 (en) * | 2000-04-05 | 2000-05-24 | Astrazeneca Ab | Combination chemotherapy |
| CN1240688C (zh) | 2000-04-07 | 2006-02-08 | 阿斯特拉曾尼卡有限公司 | 喹唑啉化合物 |
| GB0126879D0 (en) * | 2001-11-08 | 2002-01-02 | Astrazeneca Ab | Combination therapy |
| CN1625555A (zh) | 2002-02-01 | 2005-06-08 | 阿斯特拉曾尼卡有限公司 | 喹唑啉化合物 |
| GB0218526D0 (en) * | 2002-08-09 | 2002-09-18 | Astrazeneca Ab | Combination therapy |
| GB0223380D0 (en) * | 2002-10-09 | 2002-11-13 | Astrazeneca Ab | Combination therapy |
| US7462623B2 (en) | 2002-11-04 | 2008-12-09 | Astrazeneca Ab | Quinazoline derivatives as Src tyrosine kinase inhibitors |
| DE602004032310D1 (de) * | 2003-02-13 | 2011-06-01 | Astrazeneca Ab | Kombinationstherapie von zd6474 mit 5-fu oder/und cpt-11 |
| GB0310401D0 (en) * | 2003-05-07 | 2003-06-11 | Astrazeneca Ab | Therapeutic agent |
| US20060167027A1 (en) * | 2003-07-10 | 2006-07-27 | Wedge Stephen R | Use of the quinazoline derivative zd6474 combined with platinum compounds and optionally ionising radiation in the treatment of diseases associated with angiogenesis and/or increased vascular permeability |
| AU2005288737B2 (en) * | 2004-09-27 | 2008-08-14 | Astrazeneca Ab | Combination comprising ZD6474 and imatinib |
| GB0424339D0 (en) * | 2004-11-03 | 2004-12-08 | Astrazeneca Ab | Combination therapy |
| GB0519879D0 (en) | 2005-09-30 | 2005-11-09 | Astrazeneca Ab | Chemical process |
| SI1971338T1 (sl) * | 2005-12-22 | 2011-06-30 | Astrazeneca Ab | Kombinacija ZD6474 in pemetrekseda |
| JP4945133B2 (ja) * | 2006-01-19 | 2012-06-06 | 富士フイルムＲｉファーマ株式会社 | ４−フェノキシキナゾリン誘導体放射性化合物 |
| ES2399768T3 (es) * | 2006-09-29 | 2013-04-03 | Astrazeneca Ab | Combinación de ZD6474 y bevacizumab para terapia del cáncer |
| US20080190689A1 (en) * | 2007-02-12 | 2008-08-14 | Ballard Ebbin C | Inserts for engine exhaust systems |
| WO2009118560A1 (en) * | 2008-03-28 | 2009-10-01 | Astrazeneca Ab | Combination therapy 038 |
| CN106317022A (zh) * | 2015-06-25 | 2017-01-11 | 中美华世通生物医药科技（武汉）有限公司 | 化合物的制备方法和用途 |
| CN106397401B (zh) * | 2016-08-30 | 2018-11-13 | 山东罗欣药业集团股份有限公司 | 一种抗癌药物的晶体化合物及其制备方法 |
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| EE05330B1 (et) * | 1999-11-05 | 2010-08-16 | Astrazeneca Ab | Kinasoliini derivaadid kui VEGF-i inhibiitorid |
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2003
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- 2003-08-05 MX MXPA05001458A patent/MXPA05001458A/es unknown
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- 2003-08-05 EP EP03784247A patent/EP1534287A1/en not_active Withdrawn
- 2003-08-05 AU AU2003249000A patent/AU2003249000B2/en not_active Ceased
- 2003-08-05 CA CA002495487A patent/CA2495487A1/en not_active Abandoned
- 2003-08-05 US US10/523,832 patent/US20050222183A1/en not_active Abandoned
-
2005
- 2005-01-26 IL IL16652205A patent/IL166522A0/xx unknown
- 2005-01-26 NO NO20050450A patent/NO20050450L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO20050450L (no) | 2005-05-02 |
| EP1534287A1 (en) | 2005-06-01 |
| KR20050056190A (ko) | 2005-06-14 |
| CA2495487A1 (en) | 2004-02-19 |
| NZ537753A (en) | 2008-04-30 |
| WO2004014383A1 (en) | 2004-02-19 |
| BR0313116A (pt) | 2005-07-05 |
| CN1313094C (zh) | 2007-05-02 |
| IL166522A0 (en) | 2006-01-15 |
| AU2003249000A1 (en) | 2004-02-25 |
| AU2003249000B2 (en) | 2007-04-05 |
| JP2006502132A (ja) | 2006-01-19 |
| US20050222183A1 (en) | 2005-10-06 |
| CN1674905A (zh) | 2005-09-28 |
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