MXPA05000872A - Sintesis de glicoproteinas utilizando glicosiltransferasas bacterianas. - Google Patents
Sintesis de glicoproteinas utilizando glicosiltransferasas bacterianas.Info
- Publication number
- MXPA05000872A MXPA05000872A MXPA05000872A MXPA05000872A MXPA05000872A MX PA05000872 A MXPA05000872 A MX PA05000872A MX PA05000872 A MXPA05000872 A MX PA05000872A MX PA05000872 A MXPA05000872 A MX PA05000872A MX PA05000872 A MXPA05000872 A MX PA05000872A
- Authority
- MX
- Mexico
- Prior art keywords
- glycoproteins
- gycosyltransferases
- bacterial
- synthesis
- fucosyltransferases
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/005—Glycopeptides, glycoproteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
Abstract
Esta invencion proporciona acido nucleico y secuencias de acido nucleico de fucosiltransferasas de Helicobactor pylori. La invencion tambien proporciona metodos para utilizar las fucosiltransferasas para sintetizar oligosacaridos, glicoproteinas, y glicolipidos.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39815602P | 2002-07-23 | 2002-07-23 | |
US42489402P | 2002-11-08 | 2002-11-08 | |
PCT/US2003/023155 WO2004009793A2 (en) | 2002-07-23 | 2003-07-23 | Synthesis of glycoproteins using bacterial gycosyltransferases |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA05000872A true MXPA05000872A (es) | 2005-04-28 |
Family
ID=30773066
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA05000872A MXPA05000872A (es) | 2002-07-23 | 2003-07-23 | Sintesis de glicoproteinas utilizando glicosiltransferasas bacterianas. |
Country Status (10)
Country | Link |
---|---|
US (1) | US7524655B2 (es) |
EP (1) | EP1539989B1 (es) |
JP (1) | JP2005533525A (es) |
AT (1) | ATE506450T1 (es) |
AU (2) | AU2003254139A1 (es) |
CA (1) | CA2493258C (es) |
DE (1) | DE60336826D1 (es) |
MX (1) | MXPA05000872A (es) |
NZ (1) | NZ538439A (es) |
WO (2) | WO2004009838A2 (es) |
Families Citing this family (53)
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US8791070B2 (en) | 2003-04-09 | 2014-07-29 | Novo Nordisk A/S | Glycopegylated factor IX |
WO2006127896A2 (en) | 2005-05-25 | 2006-11-30 | Neose Technologies, Inc. | Glycopegylated factor ix |
ES2380093T3 (es) | 2003-05-09 | 2012-05-08 | Biogenerix Ag | Composiciones y métodos para la preparación de mutantes de glucosilación de la hormona del crecimiento humana |
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US8633157B2 (en) | 2003-11-24 | 2014-01-21 | Novo Nordisk A/S | Glycopegylated erythropoietin |
US20080305992A1 (en) | 2003-11-24 | 2008-12-11 | Neose Technologies, Inc. | Glycopegylated erythropoietin |
US7956032B2 (en) | 2003-12-03 | 2011-06-07 | Novo Nordisk A/S | Glycopegylated granulocyte colony stimulating factor |
US20060040856A1 (en) | 2003-12-03 | 2006-02-23 | Neose Technologies, Inc. | Glycopegylated factor IX |
AU2005206796B2 (en) | 2004-01-08 | 2011-06-16 | Ratiopharm Gmbh | O-linked glycosylation of peptides |
US20080300173A1 (en) | 2004-07-13 | 2008-12-04 | Defrees Shawn | Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1] |
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EP2514757A3 (en) | 2005-01-10 | 2014-03-05 | ratiopharm GmbH | Glycopegylated granulocyte colony stimulating factor |
US9187546B2 (en) | 2005-04-08 | 2015-11-17 | Novo Nordisk A/S | Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants |
WO2006108273A1 (en) | 2005-04-11 | 2006-10-19 | National Research Council Of Canada | Identification of a beta-1,3-n-acetylgalactosaminyltransferase (cgte) from campylobacter jejuni lio87 |
EP1888098A2 (en) | 2005-05-25 | 2008-02-20 | Neose Technologies, Inc. | Glycopegylated erythropoietin formulations |
FI20055398A0 (fi) | 2005-07-08 | 2005-07-08 | Suomen Punainen Risti Veripalv | Menetelmä solupopulaatioiden evaluoimiseksi |
US20070105755A1 (en) | 2005-10-26 | 2007-05-10 | Neose Technologies, Inc. | One pot desialylation and glycopegylation of therapeutic peptides |
US8969033B2 (en) * | 2005-11-02 | 2015-03-03 | Battelle Energy Alliance, Llc | Alteration and modulation of protein activity by varying post-translational modification |
WO2007056191A2 (en) | 2005-11-03 | 2007-05-18 | Neose Technologies, Inc. | Nucleotide sugar purification using membranes |
WO2008011633A2 (en) | 2006-07-21 | 2008-01-24 | Neose Technologies, Inc. | Glycosylation of peptides via o-linked glycosylation sequences |
US20100075375A1 (en) | 2006-10-03 | 2010-03-25 | Novo Nordisk A/S | Methods for the purification of polypeptide conjugates |
KR20100016160A (ko) | 2007-04-03 | 2010-02-12 | 바이오제너릭스 에이지 | 글리코페길화 g―csf를 이용하는 치료 방법 |
JP5876649B2 (ja) | 2007-06-12 | 2016-03-02 | ラツィオファルム ゲーエムベーハーratiopharm GmbH | ヌクレオチド糖の改良製造法 |
US8207112B2 (en) | 2007-08-29 | 2012-06-26 | Biogenerix Ag | Liquid formulation of G-CSF conjugate |
US9732330B2 (en) | 2008-01-25 | 2017-08-15 | Battelle Energy Alliance, Llc | Methods of combined bioprocessing and related microorganisms, thermophilic and/or acidophilic enzymes, and nucleic acids encoding said enzymes |
CA2708279A1 (en) * | 2008-01-25 | 2009-07-30 | Battelle Energy Alliance, Llc | Thermal and acid tolerant beta-xylosidases, genes encoding, related organisms, and methods |
US8492114B2 (en) | 2008-01-25 | 2013-07-23 | Battelle Energy Alliance, Llc | Methods of combined bioprocessing and related microorganisms, thermophilic and/or acidophilic enzymes, and nucleic acids encoding said enzymes |
US8497110B2 (en) | 2008-01-31 | 2013-07-30 | Battelle Energy Alliance, Llc | Thermophilic and thermoacidophilic biopolymer-degrading genes and enzymes from alicyclobacillus acidocaldarius and related organisms, methods |
EP2235174A4 (en) | 2008-01-31 | 2012-05-09 | Battelle Energy Alliance Llc | THERMOPHILIC AND THERMOACIDOPHILIC ENZYMES AND ENZYMES FOR THE DECOMPOSITION OF A BIOPOLYMER FROM ALICYCLOBACILLUS ACIDOCALDARIUS AND RELATED ORGANISMS AND METHODS THEREOF |
US8426185B2 (en) * | 2008-01-31 | 2013-04-23 | Battelle Energy Alliance, Llc | Thermophilic and thermoacidophilic biopolymer-degrading genes and enzymes from Alicyclobacillus acidocaldarius and related organisms, methods |
US8557557B2 (en) * | 2008-01-31 | 2013-10-15 | Battelle Energy Alliance, Llc | Thermophilic and thermoacidophilic biopolymer-degrading genes and enzymes from Alicyclobacillus acidocaldarius and related organisms, methods |
JP2011512799A (ja) * | 2008-02-22 | 2011-04-28 | バテル エナジー アライアンス,エルエルシー | アリサイクロバチルス・アシドカルダリウスにおける転写制御、ならびに関連遺伝子、タンパク質、および方法 |
CN102105588A (zh) | 2008-02-26 | 2011-06-22 | 巴特勒能源同盟有限公司 | 来自酸热脂环酸杆菌的嗜热的与嗜热嗜酸的糖转运蛋白的基因和酶以及相关生物、方法 |
WO2010051049A2 (en) * | 2008-02-27 | 2010-05-06 | Battelle Energy Alliance, Llc | Thermophilic and thermoacidophilic glycosylation genes and enzymes from alicyclobacillus acidocaldarius and related organisms, methods |
WO2009108806A1 (en) | 2008-02-27 | 2009-09-03 | Novo Nordisk A/S | Conjugated factor viii molecules |
JP2011512819A (ja) | 2008-02-28 | 2011-04-28 | バテル エナジー アライアンス,エルエルシー | アリサイクロバチルス・アシドカルダリウスおよび関連生物体由来の好熱性および好熱好酸性バイオポリマー分解遺伝子および酵素、方法 |
EP2166085A1 (en) | 2008-07-16 | 2010-03-24 | Suomen Punainen Risti Veripalvelu | Divalent modified cells |
US8827992B2 (en) | 2010-03-26 | 2014-09-09 | Aesculap Ag | Impedance mediated control of power delivery for electrosurgery |
US20110275135A1 (en) | 2010-05-05 | 2011-11-10 | Battelle Energy Alliance, Llc | Genetic elements, proteins, and associated methods including application of additional genetic information to gram (+) thermoacidophiles |
MY186844A (en) * | 2014-07-09 | 2021-08-25 | Cadena Bio Inc | Oligosaccharide compositions and methods for producing thereof |
WO2016040531A1 (en) | 2014-09-09 | 2016-03-17 | Glycosyn LLC | Alpha (1,3) fucosyltransferases for use in the production of fucosylated oligosaccharides |
AU2016212030B2 (en) | 2015-01-26 | 2021-06-17 | Kaleido Biosciences, Inc. | Glycan therapeutics and related methods thereof |
ES2755042T3 (es) | 2015-01-26 | 2020-04-21 | Cadena Bio Inc | Composiciones de oligosacáridos para el uso como alimento para animales y sus métodos para producirlas |
JP2018517677A (ja) | 2015-04-23 | 2018-07-05 | カレイド・バイオサイエンシズ・インコーポレイテッド | グリカン治療剤及び治療方法 |
WO2017175239A1 (en) | 2016-04-05 | 2017-10-12 | Council Of Scientific & Industrial Research | A multifunctional recombinant nucleotide dependent glycosyltransferase protein and its method of glycosylation thereof |
WO2019043457A2 (en) | 2017-09-04 | 2019-03-07 | 89Bio Ltd. | CONJUGATES OF MUTANT PEPTIDE FGF-21 AND USES THEREOF |
EP3704161A1 (en) | 2017-11-03 | 2020-09-09 | Kaleido Biosciences, Inc. | Methods of producing glycan polymers |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
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US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4935349A (en) | 1986-01-17 | 1990-06-19 | Zymogenetics, Inc. | Expression of higher eucaryotic genes in aspergillus |
US5272066A (en) | 1986-03-07 | 1993-12-21 | Massachusetts Institute Of Technology | Synthetic method for enhancing glycoprotein stability |
US5595900A (en) | 1990-02-14 | 1997-01-21 | The Regents Of The University Of Michigan | Methods and products for the synthesis of oligosaccharide structures on glycoproteins, glycolipids, or as free molecules, and for the isolation of cloned genetic sequences that determine these structures |
EP0576592B1 (en) | 1991-03-18 | 2000-05-31 | The Scripps Research Institute | Oligosaccharide enzyme substrates and inhibitors: methods and compositions |
NZ258525A (en) | 1992-11-27 | 1997-05-26 | Ciba Geigy Ag | Proteins with glycosyltransferase activity and their recombinant production |
US5374541A (en) | 1993-05-04 | 1994-12-20 | The Scripps Research Institute | Combined use of β-galactosidase and sialyltransferase coupled with in situ regeneration of CMP-sialic acid for one pot synthesis of oligosaccharides |
US5409817A (en) | 1993-05-04 | 1995-04-25 | Cytel, Inc. | Use of trans-sialidase and sialyltransferase for synthesis of sialylα2→3βgalactosides |
US5426039A (en) | 1993-09-08 | 1995-06-20 | Bio-Rad Laboratories, Inc. | Direct molecular cloning of primer extended DNA containing an alkane diol |
WO1998020111A1 (en) | 1996-11-08 | 1998-05-14 | Cytel Corporation | Improved expression vectors |
WO1998055630A2 (en) * | 1997-06-06 | 1998-12-10 | The Governors Of The University Of Alberta | Alpha-1,3-fucosyltransferase of helicobacter pylori |
US6500661B1 (en) | 1998-01-15 | 2002-12-31 | Neose Technologies, Inc. | Enzymatic conversion of GDP-mannose to GDP-fucose |
-
2003
- 2003-07-23 WO PCT/US2003/023057 patent/WO2004009838A2/en not_active Application Discontinuation
- 2003-07-23 US US10/521,138 patent/US7524655B2/en not_active Expired - Fee Related
- 2003-07-23 EP EP03766005A patent/EP1539989B1/en not_active Expired - Lifetime
- 2003-07-23 WO PCT/US2003/023155 patent/WO2004009793A2/en active Application Filing
- 2003-07-23 AU AU2003254139A patent/AU2003254139A1/en not_active Abandoned
- 2003-07-23 JP JP2005505547A patent/JP2005533525A/ja active Pending
- 2003-07-23 NZ NZ538439A patent/NZ538439A/en not_active IP Right Cessation
- 2003-07-23 AU AU2003256754A patent/AU2003256754A1/en not_active Abandoned
- 2003-07-23 DE DE60336826T patent/DE60336826D1/de not_active Expired - Lifetime
- 2003-07-23 AT AT03766005T patent/ATE506450T1/de not_active IP Right Cessation
- 2003-07-23 MX MXPA05000872A patent/MXPA05000872A/es not_active Application Discontinuation
- 2003-07-23 CA CA2493258A patent/CA2493258C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE60336826D1 (de) | 2011-06-01 |
NZ538439A (en) | 2007-02-23 |
EP1539989B1 (en) | 2011-04-20 |
WO2004009838A3 (en) | 2006-04-06 |
US7524655B2 (en) | 2009-04-28 |
WO2004009793A2 (en) | 2004-01-29 |
CA2493258C (en) | 2015-10-20 |
ATE506450T1 (de) | 2011-05-15 |
WO2004009793A3 (en) | 2004-05-13 |
AU2003254139A8 (en) | 2004-02-09 |
CA2493258A1 (en) | 2004-01-29 |
WO2004009838A2 (en) | 2004-01-29 |
US20070148728A1 (en) | 2007-06-28 |
AU2003256754A1 (en) | 2004-02-09 |
AU2003254139A1 (en) | 2004-02-09 |
EP1539989A4 (en) | 2006-09-13 |
JP2005533525A (ja) | 2005-11-10 |
EP1539989A2 (en) | 2005-06-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |