MXPA04010450A - Inhibicion antiviral de la proteina del recubrimiento capsomerico. - Google Patents
Inhibicion antiviral de la proteina del recubrimiento capsomerico.Info
- Publication number
- MXPA04010450A MXPA04010450A MXPA04010450A MXPA04010450A MXPA04010450A MX PA04010450 A MXPA04010450 A MX PA04010450A MX PA04010450 A MXPA04010450 A MX PA04010450A MX PA04010450 A MXPA04010450 A MX PA04010450A MX PA04010450 A MXPA04010450 A MX PA04010450A
- Authority
- MX
- Mexico
- Prior art keywords
- cap
- urea
- compound
- coating
- nitro
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/21—Retroviridae, e.g. equine infectious anemia virus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
- A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/30—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by halogen atoms, or by nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/40—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/42—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
- C07C281/06—Compounds containing any of the groups, e.g. semicarbazides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/18—Testing for antimicrobial activity of a material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B15/00—ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
- G16B15/20—Protein or domain folding
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B35/00—ICT specially adapted for in silico combinatorial libraries of nucleic acids, proteins or peptides
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B35/00—ICT specially adapted for in silico combinatorial libraries of nucleic acids, proteins or peptides
- G16B35/20—Screening of libraries
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
- G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
- G16C20/60—In silico combinatorial chemistry
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
- C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B15/00—ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
- G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
- G16C20/50—Molecular design, e.g. of drugs
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Computational Biology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Theoretical Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Library & Information Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Evolutionary Biology (AREA)
- Medical Informatics (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Computing Systems (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37455702P | 2002-04-22 | 2002-04-22 | |
US37585202P | 2002-04-25 | 2002-04-25 | |
US40404302P | 2002-08-16 | 2002-08-16 | |
PCT/US2003/012260 WO2003089615A2 (fr) | 2002-04-22 | 2003-04-22 | Inhibition antivirale de proteines capsidiques |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA04010450A true MXPA04010450A (es) | 2005-09-08 |
Family
ID=29255357
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA04010450A MXPA04010450A (es) | 2002-04-22 | 2003-04-22 | Inhibicion antiviral de la proteina del recubrimiento capsomerico. |
Country Status (12)
Country | Link |
---|---|
US (2) | US7361459B2 (fr) |
EP (1) | EP1513959A4 (fr) |
JP (2) | JP4431959B2 (fr) |
KR (2) | KR100960909B1 (fr) |
CN (1) | CN1656237A (fr) |
AU (1) | AU2003231012B2 (fr) |
BR (1) | BR0309485A (fr) |
CA (1) | CA2483227A1 (fr) |
IL (1) | IL164712A (fr) |
MX (1) | MXPA04010450A (fr) |
NZ (1) | NZ536737A (fr) |
WO (1) | WO2003089615A2 (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2626549A1 (fr) * | 2005-10-21 | 2007-04-26 | University Of Alabama At Birmingham | Inhibiteurs de petites molecules d'ensemble capside de vih-1 |
US8318419B2 (en) * | 2007-07-20 | 2012-11-27 | University Of Maryland, Baltimore County | Antiviral screening method to identify inhibitors of phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2] binding to the HIV gag matrix (MA) protein |
WO2009069132A2 (fr) * | 2007-11-29 | 2009-06-04 | Ramot At Tel Aviv University Ltd. | Nouveaux inhibiteurs de transcriptase inverse |
EP2335779A1 (fr) | 2008-08-08 | 2011-06-22 | New York Blood Center | Inhibiteurs de petites molécules de l'assemblage et de la maturation de rétrovirus |
US20120202814A1 (en) * | 2009-10-02 | 2012-08-09 | Università Degli Studi Di Siena | Compounds with ddx3 inhibitory activity and uses thereof |
WO2012154745A2 (fr) | 2011-05-09 | 2012-11-15 | Advanced Liquid Logic, Inc. | Rétroaction microfluidique utilisant une détection d'impédance |
CN103159686A (zh) * | 2011-12-09 | 2013-06-19 | 天津市国际生物医药联合研究院 | 一种hiv-1蛋白酶的脲类抑制剂 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6008217A (en) * | 1995-12-20 | 1999-12-28 | Vertex Pharmaceuticals Incorporated | Inhibitors of interleukin-1β converting enzyme |
US5756466A (en) * | 1994-06-17 | 1998-05-26 | Vertex Pharmaceuticals, Inc. | Inhibitors of interleukin-1β converting enzyme |
US5716929A (en) * | 1994-06-17 | 1998-02-10 | Vertex Pharmaceuticals, Inc. | Inhibitors of interleukin-1β converting enzyme |
US5663161A (en) * | 1995-02-17 | 1997-09-02 | The Research Foundation Of State University Of New York | Anti-viral triaza compounds |
US5843904A (en) * | 1995-12-20 | 1998-12-01 | Vertex Pharmaceuticals, Inc. | Inhibitors of interleukin-1βconverting enzyme |
US6593103B1 (en) * | 1997-02-07 | 2003-07-15 | The Regents Of The University Of California | HIV capsid assembly-associated compositions and method |
US20030104577A1 (en) * | 1997-02-07 | 2003-06-05 | Uc Regents | HIV capsid assembly-associated compositions and method |
US6258932B1 (en) * | 1999-08-09 | 2001-07-10 | Tripep Ab | Peptides that block viral infectivity and methods of use thereof |
EP1261746A4 (fr) * | 2000-03-06 | 2004-08-18 | Uab Research Foundation | Procede de controle de l'assemblage du vih et de sa maturation |
WO2002026783A2 (fr) * | 2000-09-28 | 2002-04-04 | Uab Research Foundation | Genes gag chimeres retroviraux et dosages de criblage |
AU2002329647A1 (en) * | 2001-07-26 | 2003-02-24 | University Of Utah Research Foundation | In vitro assays for inhibitors of hiv capsid conformational changes and for hiv capsid formation |
-
2003
- 2003-04-22 BR BRPI0309485-5A patent/BR0309485A/pt unknown
- 2003-04-22 US US10/420,438 patent/US7361459B2/en not_active Expired - Fee Related
- 2003-04-22 WO PCT/US2003/012260 patent/WO2003089615A2/fr active Application Filing
- 2003-04-22 MX MXPA04010450A patent/MXPA04010450A/es active IP Right Grant
- 2003-04-22 JP JP2003586328A patent/JP4431959B2/ja not_active Expired - Fee Related
- 2003-04-22 KR KR1020077013739A patent/KR100960909B1/ko not_active IP Right Cessation
- 2003-04-22 CA CA002483227A patent/CA2483227A1/fr not_active Abandoned
- 2003-04-22 KR KR1020047016916A patent/KR100852649B1/ko not_active IP Right Cessation
- 2003-04-22 AU AU2003231012A patent/AU2003231012B2/en not_active Ceased
- 2003-04-22 EP EP03724133A patent/EP1513959A4/fr not_active Withdrawn
- 2003-04-22 NZ NZ536737A patent/NZ536737A/en not_active IP Right Cessation
- 2003-04-22 CN CNA038121247A patent/CN1656237A/zh active Pending
-
2004
- 2004-10-19 IL IL164712A patent/IL164712A/en not_active IP Right Cessation
-
2008
- 2008-03-13 US US12/047,789 patent/US20080221215A1/en not_active Abandoned
-
2009
- 2009-05-15 JP JP2009118542A patent/JP2009300434A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US20080221215A1 (en) | 2008-09-11 |
CN1656237A (zh) | 2005-08-17 |
AU2003231012B2 (en) | 2008-05-08 |
WO2003089615A3 (fr) | 2004-03-11 |
KR100852649B1 (ko) | 2008-08-18 |
JP2005536717A (ja) | 2005-12-02 |
EP1513959A4 (fr) | 2008-07-23 |
KR20050040862A (ko) | 2005-05-03 |
JP4431959B2 (ja) | 2010-03-17 |
BR0309485A (pt) | 2007-03-06 |
IL164712A0 (en) | 2005-12-18 |
US20030228573A1 (en) | 2003-12-11 |
JP2009300434A (ja) | 2009-12-24 |
EP1513959A2 (fr) | 2005-03-16 |
KR100960909B1 (ko) | 2010-06-04 |
CA2483227A1 (fr) | 2003-10-30 |
AU2003231012A1 (en) | 2003-11-03 |
US7361459B2 (en) | 2008-04-22 |
NZ536737A (en) | 2007-04-27 |
WO2003089615A2 (fr) | 2003-10-30 |
IL164712A (en) | 2012-05-31 |
KR20070073979A (ko) | 2007-07-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Tang et al. | Antiviral inhibition of the HIV-1 capsid protein | |
US20080221215A1 (en) | Antiviral inhibition of capsid proteins | |
Zhang et al. | Antiviral activity of α-helical stapled peptides designed from the HIV-1 capsid dimerization domain | |
MXPA02001349A (es) | Inhibidores de la polimerizacion de proteinas y metodos de uso. | |
JP2009512716A (ja) | Hiv−1キャプシド構築の低分子阻害剤 | |
Saksela | Interactions of the HIV/SIV pathogenicity factor Nef with SH3 domain-containing host cell proteins | |
JP2019523647A (ja) | ジカ感染の予防および/または治療方法における使用のためのデング熱に対する中和抗体 | |
Song et al. | Multivalent agents: a novel concept and preliminary practice in Anti-HIV drug discovery | |
Mori et al. | Targeting protein-protein and protein-nucleic acid interactions for anti-HIV therapy | |
Ackerson et al. | Cells with high cyclophilin A content support replication of human immunodeficiency virus type 1 Gag mutants with decreased ability to incorporate cyclophilin A | |
WO2011139636A1 (fr) | Inhibiteurs à petites molécules de fonctions de la protéine matricielle du vih-1 | |
Dianzani et al. | In vitro selection of human immunodeficiency virus type 1 resistant to Ro 31-8959 proteinase inhibitor | |
EP2632445B1 (fr) | Nouvelle cible médicamenteuse dans gp120 du vih | |
Abdullah et al. | Discovery of dengue virus inhibitors | |
Rosé et al. | Structure-assisted design of nonpeptide human immunodeficiency virus-1 protease inhibitors | |
AU2008201880A1 (en) | Antiviral inhibitants of capsid proteins | |
KR20080024124A (ko) | 쿠프레독신과 시토크롬 c로 hiv 감염을 치료하기 위한조성물과 방법 | |
De Lucca | Synthesis and evaluation of imidazolidinones as nonpeptide HIV-protease inhibitors | |
US7012129B2 (en) | Antiviral composition comprising glycine amide | |
Debnath et al. | Molecular docking studies and absorption, distribution, metabolism and excretion prediction of novel isatin analogs as human immunodeficiency virus-1 reverse transcriptase inhibitors with broad spectrum chemotherapeutic properties | |
Spensiero | Design and synthesis of new integrase inhibitors | |
Mainkar et al. | Peptidomimetics: Current and Future Perspectives on HIV Protease Inhibitors | |
Chen | Study on the mechanism of HIV-1 maturation inhibitors on viral Gag precursor | |
Tuyishime | Investigation into the mechanism of a novel HIV-1 fusion inhibitor, SC12 | |
Kyere | Progress towards characterizing the protein interactions involved in retroviral assembly: Implication for HIV-1 assembly based inhibitors |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |