MXPA04004067A - Celulas endoteliales derivadas de embriocitos de primate. - Google Patents

Celulas endoteliales derivadas de embriocitos de primate.

Info

Publication number
MXPA04004067A
MXPA04004067A MXPA04004067A MXPA04004067A MXPA04004067A MX PA04004067 A MXPA04004067 A MX PA04004067A MX PA04004067 A MXPA04004067 A MX PA04004067A MX PA04004067 A MXPA04004067 A MX PA04004067A MX PA04004067 A MXPA04004067 A MX PA04004067A
Authority
MX
Mexico
Prior art keywords
endothelial cells
embryonic stem
primate embryonic
stem cells
derived
Prior art date
Application number
MXPA04004067A
Other languages
English (en)
Inventor
S Kaufman Dan
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of MXPA04004067A publication Critical patent/MXPA04004067A/es

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/069—Vascular Endothelial cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/38—Vitamins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/105—Insulin-like growth factors [IGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/165—Vascular endothelial growth factor [VEGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Vascular Medicine (AREA)
  • Developmental Biology & Embryology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Se describe un metodo para inducir embriocitos de primate para que se diferencien en una poblacion relativamente homogenea de celulas endoteliales. Las celulas endoteliales derivadas de ES tienen las caracteristicas morfologicas generales y los marcadores de superficie celular de las celulas endoteliales. La celulas endoteliales derivadas de ES tambien son capaces de inducir y participar en la formacion de vasos sanguineos (o vascularizacion) cuando se transplantan en tejido, in vivo.
MXPA04004067A 2001-11-02 2002-11-01 Celulas endoteliales derivadas de embriocitos de primate. MXPA04004067A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33533201P 2001-11-02 2001-11-02
PCT/US2002/035278 WO2003040319A2 (en) 2001-11-02 2002-11-01 Endothelial cells derived from primate embryonic stem cells

Publications (1)

Publication Number Publication Date
MXPA04004067A true MXPA04004067A (es) 2004-07-08

Family

ID=23311328

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04004067A MXPA04004067A (es) 2001-11-02 2002-11-01 Celulas endoteliales derivadas de embriocitos de primate.

Country Status (15)

Country Link
US (1) US7176023B2 (es)
EP (1) EP1446476A4 (es)
JP (1) JP4085062B2 (es)
KR (1) KR20050042215A (es)
CN (1) CN100540657C (es)
AU (1) AU2002356896B2 (es)
BR (1) BR0213815A (es)
CA (1) CA2465173C (es)
IL (2) IL161461A0 (es)
IS (1) IS7242A (es)
LU (1) LU91074B1 (es)
MX (1) MXPA04004067A (es)
NZ (1) NZ532170A (es)
SE (1) SE529427C8 (es)
WO (1) WO2003040319A2 (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003220424A1 (en) * 2002-03-19 2003-10-08 Advanced Research And Technology Transfer Adipose stromal stem cells for tissue and vascular modification
US20040009589A1 (en) * 2002-03-26 2004-01-15 Shulamit Levenberg Endothelial cells derived from human embryonic stem cells
JPWO2005123904A1 (ja) * 2004-06-22 2008-04-10 田辺三菱製薬株式会社 霊長類動物胚性幹細胞からの血管内皮細胞の製造方法
WO2007120811A2 (en) 2006-04-14 2007-10-25 Advanced Cell Technology, Inc. Hemangio-colony forming cells
US20080044847A1 (en) * 2006-06-23 2008-02-21 Shusta Eric V Blood-Brain Barrier Model
KR100986149B1 (ko) * 2007-09-14 2010-10-07 차의과학대학교 산학협력단 저 산소 배양액 조건을 이용한 배아 줄기 세포로부터유래된 배상체로부터 혈관 내피 전구 세포의 분화방법
WO2009104825A1 (en) 2008-02-18 2009-08-27 Kaist Method for inducing the defferentiation of embryonic stem cells into hemangioblast
RU2359030C1 (ru) * 2008-03-19 2009-06-20 Общество С Ограниченной Ответственностью "Лаборатория Клеточных Технологий" Способ получения эндотелиальных клеток из эмбриональных стволовых клеток человека (варианты)
CN102083960B (zh) 2008-05-06 2014-12-03 先进细胞技术公司 用于制备衍生自多能干细胞的去核类红细胞的方法
EP2582793B1 (en) 2010-06-15 2017-09-06 Cellular Dynamics International, Inc. A compendium of ready-built stem cell models for interrogation of biological response
WO2012006440A2 (en) 2010-07-07 2012-01-12 Cellular Dynamics International, Inc. Endothelial cell production by programming
US20120295347A1 (en) * 2011-05-20 2012-11-22 Steven Kessler Methods and Compositions for Producing Endothelial Progenitor Cells from Pluripotent Stem Cells
DK2785359T3 (en) 2011-11-30 2018-10-29 Astellas Inst For Regenerative Medicine MESENKYMAL STROMACELLES AND APPLICATIONS RELATED
CN102719393B (zh) * 2012-06-05 2014-02-12 中山大学 一种诱导肿瘤干细胞向淋巴管内皮细胞分化的无血清培养基及方法
CN105101979B (zh) 2012-12-21 2021-10-08 安斯泰来再生医药协会 由多能干细胞制备血小板的方法及其组合物
CN103194423B (zh) * 2013-03-07 2015-02-25 中国人民解放军军事医学科学院野战输血研究所 培养基及其用途
WO2014185151A1 (ja) * 2013-05-13 2014-11-20 コニカミノルタ株式会社 細胞染色方法及びその方法に使用する検体採取管
EP3003290B1 (en) 2013-06-05 2021-03-10 AgeX Therapeutics, Inc. Compositions for use in the treatment of wounds in mammalian species
US11078462B2 (en) 2014-02-18 2021-08-03 ReCyte Therapeutics, Inc. Perivascular stromal cells from primate pluripotent stem cells
US10240127B2 (en) 2014-07-03 2019-03-26 ReCyte Therapeutics, Inc. Exosomes from clonal progenitor cells
KR101756337B1 (ko) 2015-08-12 2017-07-10 고려대학교 산학협력단 Cxcr2 억제를 통한 인간 전분화능 줄기세포의 내배엽 및 중배엽 분화 방법
EP4133058A4 (en) * 2020-04-06 2024-05-08 The Board of Trustees of the Leland Stanford Junior University GENERATION OF HUMAN BLOOD POPULATIONS AND BLOOD VESSEL PROGENITORS FROM PLURIPOTENT STEM CELLS
CN115316589A (zh) * 2021-03-30 2022-11-11 云南师范大学 一种三七茎叶中凝集素的去除方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5612211A (en) * 1990-06-08 1997-03-18 New York University Stimulation, production and culturing of hematopoietic progenitor cells by fibroblast growth factors
NZ314644A (en) * 1993-05-24 2000-11-24 Immunex Corp Use of flt3-ligands as a growth stimulator of stem cells in the transplantation of tissue
JPH078273A (ja) * 1993-06-14 1995-01-13 Kurabo Ind Ltd 接着性動物細胞の無血清培養法
WO1995029713A1 (en) * 1994-04-29 1995-11-09 W.L. Gore & Associates, Inc. Improved blood contact surfaces using endothelium on a subendothelial extracellular matrix
US5843780A (en) * 1995-01-20 1998-12-01 Wisconsin Alumni Research Foundation Primate embryonic stem cells
AU3392697A (en) 1996-06-14 1998-01-07 Regents Of The University Of California, The (in vitro) derivation and culture of primate pluripotent stem cells and therapeutic uses thereof

Also Published As

Publication number Publication date
WO2003040319A3 (en) 2003-10-23
CN100540657C (zh) 2009-09-16
SE529427C8 (sv) 2007-09-25
KR20050042215A (ko) 2005-05-06
EP1446476A2 (en) 2004-08-18
NZ532170A (en) 2008-05-30
IL161461A0 (en) 2004-09-27
EP1446476A4 (en) 2005-01-26
IS7242A (is) 2004-04-30
JP2005508180A (ja) 2005-03-31
CA2465173A1 (en) 2003-05-15
CN1582331A (zh) 2005-02-16
LU91074B1 (en) 2004-04-30
US20030166273A1 (en) 2003-09-04
BR0213815A (pt) 2004-10-19
SE529427C2 (sv) 2007-08-07
WO2003040319A2 (en) 2003-05-15
CA2465173C (en) 2010-04-20
SE0401132L (sv) 2004-05-03
IL161461A (en) 2010-11-30
SE0401132D0 (sv) 2004-05-03
JP4085062B2 (ja) 2008-04-30
AU2002356896B2 (en) 2007-11-01
US7176023B2 (en) 2007-02-13

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