MXPA04003689A - Composiciones farmaceuticas y procedimientos para administrar agonistas selectivos del receptor ep2. - Google Patents
Composiciones farmaceuticas y procedimientos para administrar agonistas selectivos del receptor ep2.Info
- Publication number
- MXPA04003689A MXPA04003689A MXPA04003689A MXPA04003689A MXPA04003689A MX PA04003689 A MXPA04003689 A MX PA04003689A MX PA04003689 A MXPA04003689 A MX PA04003689A MX PA04003689 A MXPA04003689 A MX PA04003689A MX PA04003689 A MXPA04003689 A MX PA04003689A
- Authority
- MX
- Mexico
- Prior art keywords
- bone
- methods
- pharmaceutical compositions
- administering
- agonists
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
Esta invencion se refiere a composiciones farmaceuticas y a procedimientos que comprenden agonistas de prostaglandinas, especificamente agonistas selectivos del receptor EP2, que son utiles para potenciar la reparacion y la curacion de los huesos y para restaurar o aumentar la masa osea en vertebrados, particularmente en mamiferos. Los agonistas selectivos del receptor EP2 de la presente invencion son eficaces en el tratamiento de afecciones tales como aquellas en las que el paciente tiene una fractura de union retrasada o sin union, un defecto oseo, fusion espinal, crecimiento oseo hacia el interior, reconstruccion craneofacial o puntos oseos con riesgo de fractura.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33515601P | 2001-11-30 | 2001-11-30 | |
PCT/IB2002/004368 WO2003045371A1 (en) | 2001-11-30 | 2002-10-21 | Pharmaceutical compositions and methods for administering ep2 receptor selective agonists |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA04003689A true MXPA04003689A (es) | 2004-07-23 |
Family
ID=23310510
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA04003689A MXPA04003689A (es) | 2001-11-30 | 2002-10-21 | Composiciones farmaceuticas y procedimientos para administrar agonistas selectivos del receptor ep2. |
Country Status (24)
Country | Link |
---|---|
US (1) | US20030166631A1 (es) |
EP (1) | EP1448182A1 (es) |
JP (1) | JP2005513030A (es) |
KR (1) | KR20040063981A (es) |
CN (1) | CN1599605A (es) |
AR (1) | AR037593A1 (es) |
AU (1) | AU2002348948A1 (es) |
BR (1) | BR0214614A (es) |
CA (1) | CA2468494A1 (es) |
GT (1) | GT200200235A (es) |
HN (1) | HN2002000336A (es) |
IL (1) | IL161834A0 (es) |
MX (1) | MXPA04003689A (es) |
NO (1) | NO20042272L (es) |
NZ (1) | NZ532209A (es) |
PA (1) | PA8559601A1 (es) |
PE (1) | PE20030660A1 (es) |
PL (1) | PL370914A1 (es) |
RU (1) | RU2004116318A (es) |
SV (1) | SV2004001417A (es) |
TW (1) | TW200300342A (es) |
UY (1) | UY27556A1 (es) |
WO (1) | WO2003045371A1 (es) |
ZA (1) | ZA200402795B (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UA67754C2 (uk) * | 1997-10-10 | 2004-07-15 | Пфайзер, Інк. | Агоністи простагландину, фармацевтична композиція на їх основі (варіанти), спосіб нарощення та збереження кісткової маси у хребетних та спосіб лікування (варіанти) |
WO2005009468A1 (ja) * | 2003-07-25 | 2005-02-03 | Ono Pharmaceutical Co., Ltd. | 軟骨関連疾患治療剤 |
US7326732B2 (en) | 2004-02-12 | 2008-02-05 | Pharmagene Laboratories Limited | EP2 receptor agonists |
BRPI0512988A (pt) | 2004-07-08 | 2008-04-22 | Novo Nordisk As | método para aumentar a meia-vida plasmática de uma molécula, composto, uso do mesmo, e, composição farmacêutica |
CA2618486A1 (en) | 2005-08-09 | 2007-02-15 | Asterand Uk Limited | Ep2 receptor agonists |
US7915316B2 (en) * | 2005-08-22 | 2011-03-29 | Allergan, Inc | Sulfonamides |
EP1996118A4 (en) * | 2006-03-07 | 2013-03-06 | Osteoscreen Ip Llc | STRENGTHENING BONES AND CARTILES BY HMG-CO-A REDUCTASE INHIBITOR |
BRPI0714683A2 (pt) * | 2006-07-28 | 2013-03-26 | Pfizer Prod Inc | agonistas ep2 |
US8183286B2 (en) * | 2006-11-16 | 2012-05-22 | Gemmus Pharma Inc. | EP2 and EP4 agonists as agents for the treatment of influenza a viral infection |
KR101599715B1 (ko) * | 2007-08-21 | 2016-03-08 | 세노믹스, 인코포레이티드 | 인간 t2r 쓴맛 수용체 및 이의 용도 |
EP2149552A1 (de) | 2008-07-30 | 2010-02-03 | Bayer Schering Pharma AG | 5,6 substituierte Benzamid-Derivate als Modulatoren des EP2-Rezeptors |
EP2149554A1 (de) | 2008-07-30 | 2010-02-03 | Bayer Schering Pharma Aktiengesellschaft | Indolylamide als Modulatoren des EP2-Rezeptors |
EP2149551A1 (de) | 2008-07-30 | 2010-02-03 | Bayer Schering Pharma AG | N-(Indol-3-ylalkyl)-(hetero)arylamidderivate als Modulatoren des EP2-Rezeptors |
WO2010116270A1 (en) | 2009-04-10 | 2010-10-14 | Pfizer Inc. | Ep2/4 agonists |
FR3034678A1 (fr) * | 2015-04-07 | 2016-10-14 | Geocorail | Dispositif, procede et compose pour la reconstruction osseuse d'un vertebre. |
US11326183B2 (en) | 2016-02-12 | 2022-05-10 | Bluebird Bio, Inc. | VCN enhancer compositions and methods of using the same |
RU2744603C2 (ru) * | 2016-02-12 | 2021-03-11 | Блубёрд Био, Инк. | Композиции, повышающие число копий вектора (чкв), и способы их применения |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3773919A (en) * | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
US4789663A (en) * | 1984-07-06 | 1988-12-06 | Collagen Corporation | Methods of bone repair using collagen |
DE69738613T2 (de) * | 1996-12-20 | 2009-04-30 | Pfizer Inc. | Prävention und behandlung von skeletterkrankungen mit ep2 subtyp selektiven prostaglandin e2 agonisten |
UA59384C2 (uk) * | 1996-12-20 | 2003-09-15 | Пфайзер, Інк. | Похідні сульфонамідів та амідів як агоністи простагландину, фармацевтична композиція та способи лікування на їх основі |
US6071982A (en) * | 1997-04-18 | 2000-06-06 | Cambridge Scientific, Inc. | Bioerodible polymeric semi-interpenetrating network alloys for surgical plates and bone cements, and method for making same |
UA67754C2 (uk) * | 1997-10-10 | 2004-07-15 | Пфайзер, Інк. | Агоністи простагландину, фармацевтична композиція на їх основі (варіанти), спосіб нарощення та збереження кісткової маси у хребетних та спосіб лікування (варіанти) |
US20010056060A1 (en) * | 2000-02-07 | 2001-12-27 | Cameron Kimberly O. | Treatment of osteoporsis with EP2/EP4 receptor selective agonists |
-
2002
- 2002-10-21 BR BR0214614-2A patent/BR0214614A/pt not_active IP Right Cessation
- 2002-10-21 EP EP02781458A patent/EP1448182A1/en not_active Withdrawn
- 2002-10-21 CN CNA028239385A patent/CN1599605A/zh active Pending
- 2002-10-21 WO PCT/IB2002/004368 patent/WO2003045371A1/en active Application Filing
- 2002-10-21 KR KR10-2004-7008309A patent/KR20040063981A/ko not_active Application Discontinuation
- 2002-10-21 RU RU2004116318/14A patent/RU2004116318A/ru not_active Application Discontinuation
- 2002-10-21 MX MXPA04003689A patent/MXPA04003689A/es not_active Application Discontinuation
- 2002-10-21 AU AU2002348948A patent/AU2002348948A1/en not_active Abandoned
- 2002-10-21 CA CA002468494A patent/CA2468494A1/en not_active Abandoned
- 2002-10-21 JP JP2003546873A patent/JP2005513030A/ja not_active Abandoned
- 2002-10-21 NZ NZ532209A patent/NZ532209A/en unknown
- 2002-10-21 IL IL16183402A patent/IL161834A0/xx unknown
- 2002-10-21 PL PL02370914A patent/PL370914A1/xx not_active Application Discontinuation
- 2002-11-21 GT GT200200235A patent/GT200200235A/es unknown
- 2002-11-25 TW TW091134181A patent/TW200300342A/zh unknown
- 2002-11-26 PE PE2002001133A patent/PE20030660A1/es not_active Application Discontinuation
- 2002-11-26 US US10/305,649 patent/US20030166631A1/en not_active Abandoned
- 2002-11-27 HN HN2002000336A patent/HN2002000336A/es unknown
- 2002-11-28 UY UY27556A patent/UY27556A1/es not_active Application Discontinuation
- 2002-11-28 AR ARP020104592A patent/AR037593A1/es unknown
- 2002-11-29 SV SV2002001417A patent/SV2004001417A/es not_active Application Discontinuation
- 2002-11-29 PA PA20028559601A patent/PA8559601A1/es unknown
-
2004
- 2004-04-13 ZA ZA200402795A patent/ZA200402795B/en unknown
- 2004-06-01 NO NO20042272A patent/NO20042272L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA2468494A1 (en) | 2003-06-05 |
IL161834A0 (en) | 2005-11-20 |
UY27556A1 (es) | 2003-06-30 |
PA8559601A1 (es) | 2003-07-28 |
AR037593A1 (es) | 2004-11-17 |
TW200300342A (en) | 2003-06-01 |
ZA200402795B (en) | 2005-04-13 |
WO2003045371A1 (en) | 2003-06-05 |
JP2005513030A (ja) | 2005-05-12 |
EP1448182A1 (en) | 2004-08-25 |
AU2002348948A1 (en) | 2003-06-10 |
CN1599605A (zh) | 2005-03-23 |
US20030166631A1 (en) | 2003-09-04 |
PL370914A1 (en) | 2005-06-13 |
KR20040063981A (ko) | 2004-07-15 |
SV2004001417A (es) | 2004-02-24 |
BR0214614A (pt) | 2004-09-14 |
PE20030660A1 (es) | 2003-08-04 |
RU2004116318A (ru) | 2005-03-27 |
HN2002000336A (es) | 2003-02-10 |
NZ532209A (en) | 2007-05-31 |
GT200200235A (es) | 2003-06-25 |
NO20042272L (no) | 2004-07-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |