MXPA03002495A - Proceso para preparacion de compuestos de n-(fenil sustituido)-3-alquil, aril- y heteroarilsulfonil-2-hidroxi-2-alquil- y haloalquilpropanamida. - Google Patents
Proceso para preparacion de compuestos de n-(fenil sustituido)-3-alquil, aril- y heteroarilsulfonil-2-hidroxi-2-alquil- y haloalquilpropanamida.Info
- Publication number
- MXPA03002495A MXPA03002495A MXPA03002495A MXPA03002495A MXPA03002495A MX PA03002495 A MXPA03002495 A MX PA03002495A MX PA03002495 A MXPA03002495 A MX PA03002495A MX PA03002495 A MXPA03002495 A MX PA03002495A MX PA03002495 A MXPA03002495 A MX PA03002495A
- Authority
- MX
- Mexico
- Prior art keywords
- rent
- compounds
- preparation
- heteroarilsulfonil
- haloalquilpropanamida
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical class [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 title 1
- 208000002874 Acne Vulgaris Diseases 0.000 abstract 1
- 206010020112 Hirsutism Diseases 0.000 abstract 1
- 208000025844 Prostatic disease Diseases 0.000 abstract 1
- 206010039792 Seborrhoea Diseases 0.000 abstract 1
- 206010000496 acne Diseases 0.000 abstract 1
- 239000003098 androgen Substances 0.000 abstract 1
- 230000002280 anti-androgenic effect Effects 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000003211 malignant effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C315/00—Preparation of sulfones; Preparation of sulfoxides
- C07C315/02—Preparation of sulfones; Preparation of sulfoxides by formation of sulfone or sulfoxide groups by oxidation of sulfides, or by formation of sulfone groups by oxidation of sulfoxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23412100P | 2000-09-21 | 2000-09-21 | |
| PCT/US2001/042171 WO2002024638A1 (en) | 2000-09-21 | 2001-09-17 | Process for the preparation of n-(substituted phenyl)-3-alkyl-, aryl- and heteroarylsulfonyl-2-hydroxy-2-alkyl- and haloalkylpropanamide compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA03002495A true MXPA03002495A (es) | 2004-05-05 |
Family
ID=22880013
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA03002495A MXPA03002495A (es) | 2000-09-21 | 2001-09-17 | Proceso para preparacion de compuestos de n-(fenil sustituido)-3-alquil, aril- y heteroarilsulfonil-2-hidroxi-2-alquil- y haloalquilpropanamida. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6562994B2 (cs) |
| EP (1) | EP1322603A1 (cs) |
| JP (1) | JP2004509164A (cs) |
| KR (1) | KR20030048408A (cs) |
| CN (1) | CN1501912A (cs) |
| AU (1) | AU2001295044A1 (cs) |
| BR (1) | BR0114277A (cs) |
| CA (1) | CA2423158A1 (cs) |
| CZ (1) | CZ2003836A3 (cs) |
| HU (1) | HUP0302930A3 (cs) |
| IL (1) | IL155041A0 (cs) |
| MX (1) | MXPA03002495A (cs) |
| NO (1) | NO20031319D0 (cs) |
| PL (1) | PL361705A1 (cs) |
| WO (1) | WO2002024638A1 (cs) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7102026B2 (en) | 2001-06-13 | 2006-09-05 | Teva Gyógyszergyár Zártkörüen Müködö Részvénytársaság | Process for preparing and isolating rac-bicalutamide and its intermediates |
| AU2002354475B2 (en) * | 2001-12-13 | 2008-08-14 | Sumitomo Chemical Company, Limited | Crystals of bicalutamide and process for their production |
| WO2004074350A2 (en) * | 2003-02-21 | 2004-09-02 | Hetero Drugs Limited | Bicalutamide polymorphs |
| CA2529232A1 (en) * | 2003-06-25 | 2005-02-03 | Teva Gyogyszergyar Reszvenytarsasag | Process for purifying and isolating rac-bicalutamide |
| JP2005060302A (ja) * | 2003-08-12 | 2005-03-10 | Sumitomo Chemical Co Ltd | Ｎ−メタクリロイル−４−シアノ−３−トリフルオロメチルアニリンの製造方法および安定化方法 |
| JP4322621B2 (ja) | 2003-10-16 | 2009-09-02 | 住友化学株式会社 | ４’−シアノ−３−［（４−フルオロフェニル）スルホニル］−２−ヒドロキシ−２−メチル−３’−トリフルオロメチルプロピオンアニリドの製造方法 |
| US20080177109A1 (en) * | 2005-03-29 | 2008-07-24 | Usv Limited | Novel Process for Preparation of Bicalutamide |
| CA2513356A1 (en) * | 2005-07-26 | 2007-01-26 | Apotex Pharmachem Inc. | Process for production of bicalutamide |
| EP1777216A1 (en) * | 2005-09-26 | 2007-04-25 | SOLMAG S.p.A. | A process for the preparation and purification of bicalutamide |
| WO2007074473A1 (en) * | 2005-12-27 | 2007-07-05 | Dabur Pharma Limited | An improved process for preparation of bicalutamide |
| US7968603B2 (en) | 2007-09-11 | 2011-06-28 | University Of Tennessee Research Foundation | Solid forms of selective androgen receptor modulators |
| HUE036762T2 (hu) * | 2007-09-11 | 2018-07-30 | Gtx Inc | A szelektív androgén modulátor (R) vagy (S)-N-(4-ciano-3-(trifluor-metil)-fenil-3-(4-ciano-fenoxi)-2-hidroxi-2-metil-propánamid kristályos polimorfja |
| WO2009087666A2 (en) * | 2008-01-04 | 2009-07-16 | Kekule Pharma | An improved process for production of bicalutamide useful in the treatment of prostate cancer |
| WO2012042532A1 (en) | 2010-09-29 | 2012-04-05 | Shilpa Medicare Limited | Process for preparing bicalutamide |
| CN109336798B (zh) * | 2018-11-19 | 2021-11-16 | 常州新星联生物科技有限公司 | 一种比卡鲁胺硫醚中间体的制备方法 |
| CN109320442B (zh) * | 2018-11-19 | 2021-01-15 | 启东华拓药业有限公司 | 一种比卡鲁胺的合成方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB543631A (cs) * | ||||
| GB2092136B (en) * | 1981-01-17 | 1985-06-05 | Mitsui Toatsu Chemicals | Production of n-substituted amide compounds |
| DE3372965D1 (en) | 1982-07-23 | 1987-09-17 | Ici Plc | Amide derivatives |
-
2001
- 2001-09-17 CA CA002423158A patent/CA2423158A1/en not_active Abandoned
- 2001-09-17 US US09/953,759 patent/US6562994B2/en not_active Expired - Fee Related
- 2001-09-17 CN CNA018189334A patent/CN1501912A/zh active Pending
- 2001-09-17 CZ CZ2003836A patent/CZ2003836A3/cs unknown
- 2001-09-17 KR KR10-2003-7004173A patent/KR20030048408A/ko not_active Application Discontinuation
- 2001-09-17 BR BR0114277-1A patent/BR0114277A/pt not_active Expired - Fee Related
- 2001-09-17 WO PCT/US2001/042171 patent/WO2002024638A1/en not_active Application Discontinuation
- 2001-09-17 PL PL36170501A patent/PL361705A1/xx not_active Application Discontinuation
- 2001-09-17 JP JP2002529051A patent/JP2004509164A/ja active Pending
- 2001-09-17 AU AU2001295044A patent/AU2001295044A1/en not_active Abandoned
- 2001-09-17 HU HU0302930A patent/HUP0302930A3/hu unknown
- 2001-09-17 MX MXPA03002495A patent/MXPA03002495A/es active IP Right Grant
- 2001-09-17 IL IL15504101A patent/IL155041A0/xx unknown
- 2001-09-17 EP EP01975752A patent/EP1322603A1/en not_active Withdrawn
-
2003
- 2003-03-21 NO NO20031319A patent/NO20031319D0/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US6562994B2 (en) | 2003-05-13 |
| PL361705A1 (en) | 2004-10-04 |
| BR0114277A (pt) | 2004-12-21 |
| NO20031319D0 (no) | 2003-03-21 |
| JP2004509164A (ja) | 2004-03-25 |
| US20020086902A1 (en) | 2002-07-04 |
| CN1501912A (zh) | 2004-06-02 |
| CA2423158A1 (en) | 2002-03-28 |
| EP1322603A1 (en) | 2003-07-02 |
| CZ2003836A3 (cs) | 2003-08-13 |
| KR20030048408A (ko) | 2003-06-19 |
| AU2001295044A1 (en) | 2002-04-02 |
| HUP0302930A3 (en) | 2006-02-28 |
| WO2002024638A1 (en) | 2002-03-28 |
| HUP0302930A2 (hu) | 2003-12-29 |
| IL155041A0 (en) | 2003-10-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |