MXPA02001473A - Azaindoles que tienen afinidad con el receptor de serotonina. - Google Patents

Azaindoles que tienen afinidad con el receptor de serotonina.

Info

Publication number
MXPA02001473A
MXPA02001473A MXPA02001473A MXPA02001473A MXPA02001473A MX PA02001473 A MXPA02001473 A MX PA02001473A MX PA02001473 A MXPA02001473 A MX PA02001473A MX PA02001473 A MXPA02001473 A MX PA02001473A MX PA02001473 A MXPA02001473 A MX PA02001473A
Authority
MX
Mexico
Prior art keywords
group
formula
azaindoles
double bond
serotonin receptor
Prior art date
Application number
MXPA02001473A
Other languages
English (en)
Spanish (es)
Inventor
Tao Xin
Original Assignee
Nps Allelix Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nps Allelix Corp filed Critical Nps Allelix Corp
Publication of MXPA02001473A publication Critical patent/MXPA02001473A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
MXPA02001473A 1999-08-12 2000-08-14 Azaindoles que tienen afinidad con el receptor de serotonina. MXPA02001473A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14834399P 1999-08-12 1999-08-12
PCT/IB2000/001122 WO2001012629A1 (en) 1999-08-12 2000-08-14 Azaindoles having serotonin receptor affinity

Publications (1)

Publication Number Publication Date
MXPA02001473A true MXPA02001473A (es) 2003-07-21

Family

ID=22525363

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02001473A MXPA02001473A (es) 1999-08-12 2000-08-14 Azaindoles que tienen afinidad con el receptor de serotonina.

Country Status (10)

Country Link
EP (1) EP1204662B1 (https=)
JP (1) JP4969004B2 (https=)
AT (1) ATE268330T1 (https=)
AU (1) AU779832B2 (https=)
CA (1) CA2382247C (https=)
DE (1) DE60011269T2 (https=)
DK (1) DK1204662T3 (https=)
ES (1) ES2222219T3 (https=)
MX (1) MXPA02001473A (https=)
WO (1) WO2001012629A1 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10030037A1 (de) 2000-06-17 2001-12-20 Mann & Hummel Filter Zylindrische Filterpatrone mit Stützrohr
ITRM20010356A1 (it) 2001-06-21 2002-12-23 Sigma Tau Ind Farmaceuti "5-alogeno derivati della triptamina utili come ligandi del recettore5-ht6 e/o 5-ht7 della serotonina.
DE60213856T2 (de) * 2001-12-20 2007-09-13 Wyeth Indolylalkylamin-derivate als 5-hydroxytryptamin-6 liganden
TW200301251A (en) * 2001-12-20 2003-07-01 Wyeth Corp Azaindolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands
GB0202679D0 (en) * 2002-02-05 2002-03-20 Glaxo Group Ltd Novel compounds
JP2005527542A (ja) * 2002-03-27 2005-09-15 グラクソ　グループ　リミテッド キノリンおよびアザインドール誘導体およびその５−ｈｔ６リガンドとしての使用
UA78999C2 (en) * 2002-06-04 2007-05-10 Wyeth Corp 1-(aminoalkyl)-3-sulfonylazaindoles as ligands of 5-hydroxytryptamine-6
EP1897881A3 (en) 2002-06-20 2009-03-18 Biovitrum AB (publ) Compounds useful for the treatment of obesity, type II diabetes and CNS disorders
TW200403243A (en) 2002-07-18 2004-03-01 Wyeth Corp 1-Heterocyclylalkyl-3-sulfonylazaindole or-azaindazole derivatives as 5-hydroxytryptamine-6 ligands
MXPA05008137A (es) * 2003-01-31 2005-09-30 Pfizer Prod Inc Antagonistas y agonistas de 5ht7.
EP1592690A1 (en) * 2003-02-14 2005-11-09 Wyeth Heterocyclyl-3-sulfonylazaindole or -azaindazole derivatives as 5-hydroxytryptamine-6 ligands
WO2005009996A1 (en) * 2003-07-23 2005-02-03 Wyeth Sulfonyldihydro- benzimidazolone compounds as 5-hydroxytryptamine-6 ligands
ES2222828B1 (es) * 2003-07-30 2006-04-16 Laboratorios Del Dr. Esteve, S.A. Derivados de 1-sulfonilindoles, su preparacion y su aplicacion como medicamentos.
CA2637531A1 (en) * 2006-02-17 2007-08-30 Memory Pharmaceuticals Corporation Compounds having 5-ht6 receptor affinity
EP2046741B1 (en) * 2006-07-03 2012-10-31 Proximagen Ltd. Indoles as 5-ht6 modulators
EP2714688B1 (en) * 2011-05-26 2016-02-24 Daiichi Sankyo Company, Limited Heterocyclic compounds as protein kinase inhibitors
WO2015090233A1 (en) 2013-12-20 2015-06-25 Sunshine Lake Pharma Co., Ltd. Aromatic heterocyclic compounds and their application in pharmaceuticals
EP3166924B1 (en) 2014-07-08 2019-02-20 Sunshine Lake Pharma Co., Ltd. Aromatic heterocyclic derivatives and pharmaceutical applications thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI954088A0 (fi) * 1993-03-01 1995-08-31 Merck Sharp & Dohme Pyrrolopyridiinijohdannaisia
US5846982A (en) * 1996-06-14 1998-12-08 Eli Lilly And Company Inhibition of serotonin reuptake
EP0875513A1 (en) * 1997-04-14 1998-11-04 Eli Lilly And Company Substituted heteroaromatic 5-HT 1F agonists
US5905084A (en) * 1997-11-14 1999-05-18 Eli Lilly And Company 5-HTIF -agonists effective in treating migraine
US6562809B1 (en) * 1998-09-18 2003-05-13 Nps Allelix Corp. 3-bicycloindole compounds

Also Published As

Publication number Publication date
EP1204662A1 (en) 2002-05-15
JP4969004B2 (ja) 2012-07-04
WO2001012629A1 (en) 2001-02-22
CA2382247A1 (en) 2001-02-22
AU6310300A (en) 2001-03-13
EP1204662B1 (en) 2004-06-02
AU779832B2 (en) 2005-02-10
ES2222219T3 (es) 2005-02-01
DK1204662T3 (da) 2004-10-04
DE60011269T2 (de) 2005-06-23
CA2382247C (en) 2010-09-28
ATE268330T1 (de) 2004-06-15
DE60011269D1 (de) 2004-07-08
JP2003507380A (ja) 2003-02-25

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Legal Events

Date Code Title Description
FG Grant or registration
GB Transfer or rights
HC Change of company name or juridical status