MXPA01005370A - Sistema de matriz de liberacion sostenida para farmacos altamente solubles. - Google Patents
Sistema de matriz de liberacion sostenida para farmacos altamente solubles.Info
- Publication number
- MXPA01005370A MXPA01005370A MXPA01005370A MXPA01005370A MXPA01005370A MX PA01005370 A MXPA01005370 A MX PA01005370A MX PA01005370 A MXPA01005370 A MX PA01005370A MX PA01005370 A MXPA01005370 A MX PA01005370A MX PA01005370 A MXPA01005370 A MX PA01005370A
- Authority
- MX
- Mexico
- Prior art keywords
- sustained release
- release matrix
- highly soluble
- soluble drugs
- matrix systems
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Inorganic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Se revelan foemas de dosis solida oral de liberacion sostenida que comprenden una cantidad terapeuticamente efectiva y un medicamento, que posee una solubilidad de mas de 10g/1; un agente modificador delPh y una matriz de liberacion sostenida que comprende un agente gelificante, donde el agente gelificante comprende una goma heteropolisacarida y una goma homopolisacarida capaz de entrelazar la goma heteropolisacarida al exponerla a un fluido del entorno, donde la forma de dosis proporciona una liberacion sostenida del medicamento tras administrarse oralmente a pacientes humanos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15720099P | 1999-09-30 | 1999-09-30 | |
PCT/US2000/026871 WO2001022940A1 (en) | 1999-09-30 | 2000-09-29 | Sustained release matrix systems for highly soluble drugs |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA01005370A true MXPA01005370A (es) | 2004-05-14 |
Family
ID=22562739
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA01005370A MXPA01005370A (es) | 1999-09-30 | 2000-09-29 | Sistema de matriz de liberacion sostenida para farmacos altamente solubles. |
Country Status (16)
Country | Link |
---|---|
US (3) | US20040170684A1 (es) |
EP (1) | EP1135106B1 (es) |
JP (2) | JP3893058B2 (es) |
KR (1) | KR100463496B1 (es) |
CN (1) | CN1228043C (es) |
AT (1) | ATE391495T1 (es) |
AU (1) | AU762291B2 (es) |
CA (1) | CA2352211C (es) |
DE (1) | DE60038536T2 (es) |
ES (1) | ES2304980T3 (es) |
HK (1) | HK1042427A1 (es) |
HU (1) | HUP0104472A3 (es) |
IL (2) | IL143375A0 (es) |
MX (1) | MXPA01005370A (es) |
NZ (1) | NZ511900A (es) |
WO (1) | WO2001022940A1 (es) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
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CA2452872A1 (en) | 2001-07-06 | 2003-01-16 | Endo Pharmaceuticals, Inc. | Parenteral administration of 6-hydroxy-oxymorphone for use as an analgesic |
AU2002337686B2 (en) * | 2001-09-26 | 2008-05-15 | Penwest Pharmaceuticals Company | Opioid formulations having reduced potential for abuse |
EP1499295A4 (en) * | 2002-04-05 | 2006-04-05 | Penwest Pharmaceuticals Co | EXTENDED RELEASE METOPROLOL FORMULATIONS |
US7214387B2 (en) | 2002-08-02 | 2007-05-08 | Penwest Pharmaceuticals Company | Sustained release formulations of metformin |
US20060134210A1 (en) * | 2004-12-22 | 2006-06-22 | Astrazeneca Ab | Solid dosage form comprising proton pump inhibitor and suspension made thereof |
US20060228413A1 (en) * | 2005-02-28 | 2006-10-12 | Penwest Pharmaceuticals Co. | Controlled release venlafaxine formulations |
US8394812B2 (en) | 2005-08-24 | 2013-03-12 | Penwest Pharmaceuticals Co. | Sustained release formulations of nalbuphine |
DK1931315T3 (da) | 2005-08-24 | 2014-01-20 | Endo Pharmaceuticals Inc | Depotformuleringer af nalbufin |
US20070098791A1 (en) * | 2005-10-31 | 2007-05-03 | Rekhi Gurvinder S | Controlled release compositions comprising a combination of isosorbide dinitrate and hydralazine hydrochloride |
US20070098796A1 (en) | 2005-10-31 | 2007-05-03 | Rekhi Gurvinder S | Controlled release compositions comprising a combination of isosorbide dinitrate and hydralazine hydrochrloride |
WO2007055329A1 (ja) | 2005-11-11 | 2007-05-18 | Asahi Kasei Chemicals Corporation | 徐放性固形製剤 |
US8747897B2 (en) | 2006-04-27 | 2014-06-10 | Supernus Pharmaceuticals, Inc. | Osmotic drug delivery system |
WO2008079868A1 (en) * | 2006-12-22 | 2008-07-03 | Drugtech Corporation | Clonidine composition and method of use |
JP2010529142A (ja) * | 2007-06-08 | 2010-08-26 | アドレネクス・ファーマシューティカルズ,インコーポレイテッド | アドレナリン調節異常症を治療する徐放性の製剤および方法 |
US20100172991A1 (en) * | 2007-06-08 | 2010-07-08 | Henry Joseph Horacek | Extended Release Formulation and Methods of Treating Adrenergic Dysregulation |
WO2010026467A2 (en) * | 2008-09-04 | 2010-03-11 | Torrent Pharmaceuticals Ltd. | Controlled release dosage form of high solubility active ingredient |
US20100173907A1 (en) | 2008-12-19 | 2010-07-08 | Supernus Pharmaceuticals, Inc. | Method of treatment of aggression |
CN101596170B (zh) * | 2009-07-06 | 2011-11-23 | 沈阳亿灵医药科技有限公司 | 曲司氯氨缓释片 |
EP2316432A1 (de) * | 2009-10-30 | 2011-05-04 | ratiopharm GmbH | Zusammensetzung enthaltend Fesoterodin und Ballaststoffe |
EP2544667B1 (en) * | 2010-03-09 | 2018-11-14 | Alkermes Pharma Ireland Limited | Alcohol resistant enteric pharmaceutical compositions |
CA2793222C (en) * | 2010-03-31 | 2018-01-23 | Supernus Pharmaceuticals, Inc. | Stabilized formulations of cns compounds |
US8623409B1 (en) | 2010-10-20 | 2014-01-07 | Tris Pharma Inc. | Clonidine formulation |
AU2013235266B2 (en) | 2012-03-20 | 2017-10-19 | Particle Dynamics International, Llc | Gelling agent-based dosage form |
GB201417828D0 (en) | 2014-10-08 | 2014-11-19 | Cereno Scient Ab | New methods and compositions |
ES2969021T3 (es) * | 2016-04-08 | 2024-05-16 | Cereno Scient Ab | Formulaciones farmacéuticas de liberación retardada que comprenden ácido valproico y usos de las mismas |
WO2019234763A1 (en) * | 2018-06-06 | 2019-12-12 | Wallace Pharmaceuticals Pvt. Ltd. | Lincomycin sustained release tablets 1000mg |
US11918689B1 (en) | 2020-07-28 | 2024-03-05 | Tris Pharma Inc | Liquid clonidine extended release composition |
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DE2714065A1 (de) | 1977-03-30 | 1978-10-12 | Boehringer Mannheim Gmbh | Instillationszubereitung |
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-
2000
- 2000-09-29 CA CA002352211A patent/CA2352211C/en not_active Expired - Fee Related
- 2000-09-29 ES ES00968498T patent/ES2304980T3/es not_active Expired - Lifetime
- 2000-09-29 AT AT00968498T patent/ATE391495T1/de not_active IP Right Cessation
- 2000-09-29 NZ NZ511900A patent/NZ511900A/xx not_active IP Right Cessation
- 2000-09-29 WO PCT/US2000/026871 patent/WO2001022940A1/en active Application Filing
- 2000-09-29 KR KR10-2001-7006695A patent/KR100463496B1/ko not_active IP Right Cessation
- 2000-09-29 EP EP00968498A patent/EP1135106B1/en not_active Expired - Lifetime
- 2000-09-29 DE DE60038536T patent/DE60038536T2/de not_active Expired - Lifetime
- 2000-09-29 MX MXPA01005370A patent/MXPA01005370A/es active IP Right Grant
- 2000-09-29 IL IL14337500A patent/IL143375A0/xx unknown
- 2000-09-29 AU AU78401/00A patent/AU762291B2/en not_active Ceased
- 2000-09-29 HU HU0104472A patent/HUP0104472A3/hu unknown
- 2000-09-29 CN CNB008025134A patent/CN1228043C/zh not_active Expired - Fee Related
- 2000-09-29 JP JP2001526152A patent/JP3893058B2/ja not_active Expired - Fee Related
-
2001
- 2001-05-24 IL IL143375A patent/IL143375A/en unknown
-
2002
- 2002-03-26 HK HK02102317.0A patent/HK1042427A1/zh unknown
-
2003
- 2003-12-18 US US10/740,213 patent/US20040170684A1/en not_active Abandoned
-
2006
- 2006-08-02 JP JP2006211366A patent/JP2006306893A/ja active Pending
-
2007
- 2007-03-27 US US11/729,024 patent/US8679535B2/en not_active Expired - Fee Related
-
2014
- 2014-03-03 US US14/195,127 patent/US20140242166A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU7840100A (en) | 2001-04-30 |
US20040170684A1 (en) | 2004-09-02 |
EP1135106B1 (en) | 2008-04-09 |
WO2001022940A1 (en) | 2001-04-05 |
CN1228043C (zh) | 2005-11-23 |
ES2304980T3 (es) | 2008-11-01 |
JP2006306893A (ja) | 2006-11-09 |
DE60038536D1 (de) | 2008-05-21 |
HUP0104472A2 (hu) | 2002-04-29 |
DE60038536T2 (de) | 2009-06-10 |
IL143375A (en) | 2009-07-20 |
HK1042427A1 (zh) | 2002-08-16 |
NZ511900A (en) | 2003-06-30 |
AU762291B2 (en) | 2003-06-19 |
JP2003510265A (ja) | 2003-03-18 |
ATE391495T1 (de) | 2008-04-15 |
EP1135106A1 (en) | 2001-09-26 |
CN1335767A (zh) | 2002-02-13 |
KR20010086062A (ko) | 2001-09-07 |
CA2352211C (en) | 2009-03-24 |
HUP0104472A3 (en) | 2002-12-28 |
US20070218137A1 (en) | 2007-09-20 |
US20140242166A1 (en) | 2014-08-28 |
EP1135106A4 (en) | 2005-07-06 |
JP3893058B2 (ja) | 2007-03-14 |
IL143375A0 (en) | 2002-04-21 |
KR100463496B1 (ko) | 2005-01-06 |
US8679535B2 (en) | 2014-03-25 |
CA2352211A1 (en) | 2001-04-05 |
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