MX9805098A - Inhibidor de oxido nitrico (on) sintetasa para tratar o prevenir diabetes de tipo ii. - Google Patents

Inhibidor de oxido nitrico (on) sintetasa para tratar o prevenir diabetes de tipo ii.

Info

Publication number
MX9805098A
MX9805098A MX9805098A MX9805098A MX9805098A MX 9805098 A MX9805098 A MX 9805098A MX 9805098 A MX9805098 A MX 9805098A MX 9805098 A MX9805098 A MX 9805098A MX 9805098 A MX9805098 A MX 9805098A
Authority
MX
Mexico
Prior art keywords
diabetes
treat
synthase inhibitor
nitric oxide
prevent type
Prior art date
Application number
MX9805098A
Other languages
English (en)
Inventor
Nicholas Charles Turner
Valerie Piercy
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of MX9805098A publication Critical patent/MX9805098A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Un método para el tratamiento y/o profilaxis de diabetes de Tipo II, cuyo método comprende la administracion, a un mamífero humano o no humano, de una cantidad farmacéuticamente aceptable, no toxica, efectiva, de un inhibidor de ON sintetasa tal como la aminoguanidina, o un derivado farmacéuticamente aceptable de la misma.
MX9805098A 1995-12-22 1998-06-22 Inhibidor de oxido nitrico (on) sintetasa para tratar o prevenir diabetes de tipo ii. MX9805098A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9526331.5A GB9526331D0 (en) 1995-12-22 1995-12-22 Novel method

Publications (1)

Publication Number Publication Date
MX9805098A true MX9805098A (es) 1998-10-31

Family

ID=10785930

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9805098A MX9805098A (es) 1995-12-22 1998-06-22 Inhibidor de oxido nitrico (on) sintetasa para tratar o prevenir diabetes de tipo ii.

Country Status (20)

Country Link
EP (1) EP0868175B1 (es)
JP (1) JP2000502668A (es)
KR (1) KR19990076595A (es)
CN (1) CN1209057A (es)
AT (1) ATE232724T1 (es)
AU (1) AU1379497A (es)
BR (1) BR9612245A (es)
CA (1) CA2240396A1 (es)
CZ (1) CZ198698A3 (es)
DE (1) DE69626307T2 (es)
ES (1) ES2193285T3 (es)
GB (1) GB9526331D0 (es)
HU (1) HUP9903979A3 (es)
IL (1) IL124870A0 (es)
MX (1) MX9805098A (es)
NO (1) NO982854D0 (es)
NZ (1) NZ325307A (es)
PL (1) PL327472A1 (es)
TR (1) TR199801133T2 (es)
WO (1) WO1997023204A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999044598A2 (en) * 1998-03-03 1999-09-10 Board Of Regents, The University Of Texas System Methods for inhibiting βcell apoptosis
CN1660428B (zh) * 2005-01-10 2011-09-07 王振军 一氧化氮合酶（nos）抑制剂用于治疗痔的新用途
ES2386831B1 (es) * 2011-02-04 2013-07-08 Servicio Andaluz De Salud Uso de inhibidores de la actividad de las NO sintasas (NOS) y sus composiciones, en la elaboración de un medicamento para el tratamiento y la prevención de la prediabetes y la diabetes mellitus tipo 1 (DM1)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE793646T1 (de) * 1994-11-23 1999-12-30 Upjohn Co Carboxylierte aminoguanidine zum behandlung von insulin-unabhängigem diabetes mellitus

Also Published As

Publication number Publication date
PL327472A1 (en) 1998-12-07
EP0868175A1 (en) 1998-10-07
HUP9903979A3 (en) 2000-05-29
DE69626307D1 (de) 2003-03-27
NO982854L (no) 1998-06-19
ES2193285T3 (es) 2003-11-01
KR19990076595A (ko) 1999-10-15
NO982854D0 (no) 1998-06-19
CN1209057A (zh) 1999-02-24
NZ325307A (en) 1999-11-29
AU1379497A (en) 1997-07-17
TR199801133T2 (xx) 1998-09-21
BR9612245A (pt) 1999-07-13
CA2240396A1 (en) 1997-07-03
JP2000502668A (ja) 2000-03-07
CZ198698A3 (cs) 1999-06-16
HUP9903979A2 (hu) 2000-03-28
DE69626307T2 (de) 2003-10-16
IL124870A0 (en) 1999-01-26
ATE232724T1 (de) 2003-03-15
EP0868175B1 (en) 2003-02-19
GB9526331D0 (en) 1996-02-21
WO1997023204A1 (en) 1997-07-03

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