MX9804701A - METODO Y COMPOSICIONES PARA LA SINTESIS DE NUCLEOSIDAS DE DIOXOLANO CON CONFIGURACION beta. - Google Patents

METODO Y COMPOSICIONES PARA LA SINTESIS DE NUCLEOSIDAS DE DIOXOLANO CON CONFIGURACION beta.

Info

Publication number
MX9804701A
MX9804701A MX9804701A MX9804701A MX9804701A MX 9804701 A MX9804701 A MX 9804701A MX 9804701 A MX9804701 A MX 9804701A MX 9804701 A MX9804701 A MX 9804701A MX 9804701 A MX9804701 A MX 9804701A
Authority
MX
Mexico
Prior art keywords
beta
compositions
synthesis
configuration
dioxolane nucleosides
Prior art date
Application number
MX9804701A
Other languages
English (en)
Spanish (es)
Inventor
Tarek Mansour
Alex Cimpoia
Krzysztof Bednarski
Original Assignee
Iaf Biochem Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iaf Biochem Int filed Critical Iaf Biochem Int
Publication of MX9804701A publication Critical patent/MX9804701A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
MX9804701A 1995-12-14 1998-06-11 METODO Y COMPOSICIONES PARA LA SINTESIS DE NUCLEOSIDAS DE DIOXOLANO CON CONFIGURACION beta. MX9804701A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9525606.1A GB9525606D0 (en) 1995-12-14 1995-12-14 Method and compositions for the synthesis of dioxolane nucleosides with › - configuration

Publications (1)

Publication Number Publication Date
MX9804701A true MX9804701A (es) 1998-10-31

Family

ID=10785435

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9804701A MX9804701A (es) 1995-12-14 1998-06-11 METODO Y COMPOSICIONES PARA LA SINTESIS DE NUCLEOSIDAS DE DIOXOLANO CON CONFIGURACION beta.

Country Status (27)

Country Link
US (4) US5922867A (oth)
EP (1) EP0970074B1 (oth)
JP (1) JP3229990B2 (oth)
KR (1) KR100406159B1 (oth)
CN (1) CN1080263C (oth)
AP (1) AP879A (oth)
AT (1) ATE214699T1 (oth)
AU (1) AU706328B2 (oth)
BR (1) BR9612351A (oth)
CA (1) CA2237730C (oth)
DE (1) DE69620042T2 (oth)
DK (1) DK0970074T3 (oth)
EA (1) EA000844B1 (oth)
ES (1) ES2172697T3 (oth)
GB (1) GB9525606D0 (oth)
HU (1) HU224076B1 (oth)
IL (3) IL124663A (oth)
IN (1) IN187349B (oth)
MX (1) MX9804701A (oth)
NO (1) NO309901B1 (oth)
NZ (1) NZ323855A (oth)
OA (1) OA11094A (oth)
PL (1) PL188447B1 (oth)
PT (1) PT970074E (oth)
TW (1) TW341574B (oth)
WO (1) WO1997021706A1 (oth)
ZA (1) ZA9610544B (oth)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001518899A (ja) 1997-04-07 2001-10-16 トライアングル ファーマシューティカルズ，インコーポレイティド 他の抗ウイルス剤との組合せにおけるｍｋｃ−４４２の使用
PT2322518E (pt) 1998-08-12 2015-06-08 Gilead Sciences Inc Métodos de fabrico de nucleosídeos de 1,3-dioxolano e 1,3 oxatiolano
US6979561B1 (en) 1998-10-09 2005-12-27 Gilead Sciences, Inc. Non-homogeneous systems for the resolution of enantiomeric mixtures
NZ513094A (en) 1998-12-23 2004-05-28 Shire Biochem Inc Antiviral nucleoside analogues
CA2362570A1 (en) * 1999-02-11 2000-08-17 Shire Biochem Inc. Stereoselective synthesis of nucleoside analogues
AU777869B2 (en) * 1999-09-24 2004-11-04 Shire Canada Inc. Method for the treatment or prevention of viral infection using nucleoside analogues
US6566365B1 (en) 1999-11-04 2003-05-20 Biochem Pharma Inc. Method for the treatment of Flaviviridea viral infection using nucleoside analogues
US7038039B2 (en) * 2000-02-10 2006-05-02 Mitsui Chemicals, Inc. Process for selectively producing 1-phosphorylated sugar derivative anomer and process for producing nucleoside
ES2284613T3 (es) 2000-02-11 2007-11-16 Shire Biochem Inc. Sintesis estereoselectiva de analogos de nucleosido.
WO2002051852A1 (fr) * 2000-12-27 2002-07-04 Mitsui Chemicals, Inc. Procede de production d'un derive de saccharide non naturel
ES2299950T3 (es) * 2001-03-01 2008-06-01 Abbott Laboratories Formas polimorficas y otras formas cristalinas cis-ftc.
AU2002329970A1 (en) * 2001-09-04 2003-03-18 Isis Pharmaceuticals, Inc. Pyrrolo(2,3-d)pyrimidines for inhibiting rna-dependent rna viral polymerase
WO2003037344A1 (en) * 2001-11-02 2003-05-08 Shire Biochem Inc. Pharmaceutical compositions for the treatment of leukemia comprising dioxolane nucleosides analogs
JP2005519916A (ja) * 2001-12-14 2005-07-07 フアーマセツト・リミテツド ウィルス感染治療用ｎ４−アシルシトシンヌクレオシド類
CA2473736C (en) * 2002-01-25 2011-10-11 Shire Biochem Inc. Process for producing dioxolane nucleoside analogues
DE60335805D1 (de) 2002-08-06 2011-03-03 Pharmasset Inc Verfahren zur herstellung von 1,3-dioxolan-nucleosiden
KR101113341B1 (ko) 2002-10-15 2012-09-27 엑손모빌 케미칼 패턴츠 인코포레이티드 올레핀 중합용 다중 촉매 시스템 및 이로부터 제조된중합체
DE10335061B4 (de) * 2003-07-31 2005-11-17 Wacker-Chemie Gmbh Verfahren zur Herstellung von OH-geschützten [4-(2,6-damino-9H-purin-9-yl)-1,3-dioxolan-2-yl]methanol-Derivaten
US7785839B2 (en) 2004-02-03 2010-08-31 Emory University Methods to manufacture 1,3-dioxolane nucleosides
US7749531B2 (en) * 2005-06-08 2010-07-06 Indicator Systems International Apparatus and method for detecting bacterial growth beneath a wound dressing
BRPI0813036A2 (pt) * 2007-07-30 2017-10-24 Rfs Pharma Llc processo estereosseletivo para preparar derivados do nucleosídeo dioxolana de purina.
CN101862676B (zh) * 2009-04-17 2012-01-25 中国石油化工股份有限公司 大孔径sba-15介孔材料-三氟甲磺酸铜复合催化剂、制备方法及应用
CN103288806A (zh) * 2013-07-02 2013-09-11 山东大学 一种曲沙他滨的合成方法
WO2018022263A1 (en) 2016-07-29 2018-02-01 Exxonmobil Chemical Patents Inc. Polymerization processes using high molecular weight polyhydric quenching agents
JP7337539B2 (ja) 2018-06-21 2023-09-04 メディヴィル・アクチエボラーグ 白血病療法のための塩基修飾シチジンヌクレオチド
WO2019245444A1 (en) 2018-06-21 2019-12-26 Medivir Ab Base-modified cytidine nucleotides for leukemia therapy

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5276151A (en) * 1990-02-01 1994-01-04 Emory University Method of synthesis of 1,3-dioxolane nucleosides
IL106078A0 (en) * 1992-06-22 1993-10-20 Lilly Co Eli Stereoselective anion glycosylation process

Also Published As

Publication number Publication date
CN1208414A (zh) 1999-02-17
EA000844B1 (ru) 2000-06-26
EA199800555A1 (ru) 1999-02-25
PT970074E (pt) 2002-09-30
GB9525606D0 (en) 1996-02-14
DE69620042T2 (de) 2002-10-17
EP0970074A1 (en) 2000-01-12
OA11094A (en) 2003-03-13
HUP9901050A2 (hu) 2001-04-28
ZA9610544B (en) 1997-07-29
AP879A (en) 2000-10-02
IL144155A (en) 2003-07-06
TW341574B (en) 1998-10-01
PL327443A1 (en) 1998-12-07
US5922867A (en) 1999-07-13
US20030060476A1 (en) 2003-03-27
CN1080263C (zh) 2002-03-06
BR9612351A (pt) 1999-07-13
US20020058670A1 (en) 2002-05-16
US6069250A (en) 2000-05-30
IL124663A0 (en) 1998-12-06
IL124663A (en) 2001-10-31
KR100406159B1 (ko) 2004-11-16
ES2172697T3 (es) 2002-10-01
IL144155A0 (en) 2002-05-23
AP9801252A0 (en) 1998-06-30
EP0970074B1 (en) 2002-03-20
HUP9901050A3 (en) 2001-05-28
JP3229990B2 (ja) 2001-11-19
AU706328B2 (en) 1999-06-17
WO1997021706A1 (en) 1997-06-19
HU224076B1 (hu) 2005-05-30
NO982716L (no) 1998-06-12
NO982716D0 (no) 1998-06-12
CA2237730A1 (en) 1997-06-19
IN187349B (oth) 2002-03-30
AU1089397A (en) 1997-07-03
NO309901B1 (no) 2001-04-17
NZ323855A (en) 1999-11-29
HK1017886A1 (en) 1999-12-03
DE69620042D1 (de) 2002-04-25
PL188447B1 (pl) 2005-02-28
ATE214699T1 (de) 2002-04-15
DK0970074T3 (da) 2002-07-15
KR19990072141A (ko) 1999-09-27
JP2000501714A (ja) 2000-02-15
CA2237730C (en) 2001-12-04

Similar Documents

Publication Publication Date Title
MX9804701A (es) METODO Y COMPOSICIONES PARA LA SINTESIS DE NUCLEOSIDAS DE DIOXOLANO CON CONFIGURACION beta.
DK0594291T3 (da) Fremgangsmåder til fremstilling af 13-etherderivater af milbemyciner og mellemprodukter dertil
DK0513200T3 (da) Fremgangsmåde og sammensætninger til syntese af BCH-189 og beslægtede forbindelser
ZA911153B (en) Process for the preparation of oxetanones
IL87517A0 (en) Improvements in or relating to 2',2'-difluoronucleosides
BG101794A (en) Method for the preparation of trihydrate of (2r, 3s)-3-benzoylamino-2-hydroxy-3-phenylpropionate of 4, 10-diacetoxy-2 alpha-benzoyloxy-5 beta, 20-epoxy-1,7 beta -dihydroxy-9-oco-tax-11-en-13 alpha-yl
SI1049686T1 (sl) Intermediati in postopki, uporabni pri semisintezi paklitaksela in analogov
AU567855B2 (en) Method of promoting seedling emergence of field-planted, small seeded crops
NO974512D0 (no) Fremgangsmåte for syntese av nukleosid-analoger
CA2332974A1 (en) Morphine-6-glucuronide synthesis
IL131513A0 (en) Method for producing 1,3-di-substituted 2-nitroguanidines
HUP9702365A3 (en) Application of hydroxilamin-derivatives, as well as process and composition for increase of weather extreme resistent by cultivated plants
DK0640142T3 (da) Fremgangsmåde til fremtilling af avermectiner og kulturer hertil
ES8609203A1 (es) Un procedimiento para preparar 1,5,10-triazadecanos susti- tuidos en posicion 5
HU9503816D0 (en) Process for producing of rodenticide composition with long storetime by tropical conditions