MX9709247A - Nueva proteina antiproliferativa del bacillus thuringiensis variedad thuringiensis. - Google Patents
Nueva proteina antiproliferativa del bacillus thuringiensis variedad thuringiensis.Info
- Publication number
- MX9709247A MX9709247A MX9709247A MX9709247A MX9709247A MX 9709247 A MX9709247 A MX 9709247A MX 9709247 A MX9709247 A MX 9709247A MX 9709247 A MX9709247 A MX 9709247A MX 9709247 A MX9709247 A MX 9709247A
- Authority
- MX
- Mexico
- Prior art keywords
- thuringiensis
- protein
- var
- bacillus thuringiensis
- present
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
- C07K14/325—Bacillus thuringiensis crystal protein (delta-endotoxin)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Abstract
La presente invencion proporciona una proteína aislada y purificada derivada del Bacillus thuringiensis subespecie thuringiensis, que tienen un peso molecular de aproximadamente 20kDa de SDS-PAGE, la proteína tiene la secuencia de aminoácidos parcial mostrada en la SEQ ID No. 1, y en donde la proteína exhibe efectos citotoxicos contra las células tumorígenas. También se proporciona un método de tratamiento de una célula neoplástica que comprende administrar una dosis efectiva terapéuticamente de la composicion de la presente invencion a la célula.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45463695A | 1995-05-31 | 1995-05-31 | |
| US454636 | 1995-05-31 | ||
| US454,636 | 1995-05-31 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX9709247A true MX9709247A (es) | 1998-10-31 |
| MXPA97009247A MXPA97009247A (es) | 1999-01-11 |
Family
ID=
Also Published As
| Publication number | Publication date |
|---|---|
| EP0835260A1 (en) | 1998-04-15 |
| JPH11507025A (ja) | 1999-06-22 |
| TW557299B (en) | 2003-10-11 |
| CN1144816C (zh) | 2004-04-07 |
| EP0835260A4 (en) | 1999-06-02 |
| DE69624570T2 (de) | 2003-03-20 |
| RU2178798C2 (ru) | 2002-01-27 |
| CA2234794A1 (en) | 1996-12-05 |
| DE69624570D1 (en) | 2002-12-05 |
| EP0835260B1 (en) | 2002-10-30 |
| CN1192220A (zh) | 1998-09-02 |
| US5824636A (en) | 1998-10-20 |
| ZA964359B (en) | 1998-07-29 |
| AU6028196A (en) | 1996-12-18 |
| ES2181889T3 (es) | 2003-03-01 |
| WO1996038477A1 (en) | 1996-12-05 |
| CA2234794C (en) | 2008-05-13 |
| JP3786962B2 (ja) | 2006-06-21 |
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