AU2001220255A1 - Human cervical cancer suppressor protein, polynucleotide encoding the protein, cell transformed with the polynucleotide and method for suppressing proliferationof cancer cell using the expression vector - Google Patents

Human cervical cancer suppressor protein, polynucleotide encoding the protein, cell transformed with the polynucleotide and method for suppressing proliferationof cancer cell using the expression vector

Info

Publication number
AU2001220255A1
AU2001220255A1 AU2001220255A AU2025501A AU2001220255A1 AU 2001220255 A1 AU2001220255 A1 AU 2001220255A1 AU 2001220255 A AU2001220255 A AU 2001220255A AU 2025501 A AU2025501 A AU 2025501A AU 2001220255 A1 AU2001220255 A1 AU 2001220255A1
Authority
AU
Australia
Prior art keywords
polynucleotide
protein
expression vector
cell
suppressing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001220255A
Inventor
Jin Woo Kim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of AU2001220255A1 publication Critical patent/AU2001220255A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

The present invention provides a human tumor suppressor protein having the amino acid sequence of SEQ ID NO: 2; a polynucleotide encoding the tumor suppressor protein; an expression vector containing the polynucleotide; a microorganism or animal cell transformed with the expression vector; a method for suppressing proliferation of a cancer cell which comprises introducing the expression vector into a cancer cell to induce apoptosis thereof; and a pharmaceutical composition for preventing or treating cancer which comprises a therapeutically effective amount of the polynucleotide and a pharmaceutically acceptable carrier.
AU2001220255A 2000-04-25 2000-12-04 Human cervical cancer suppressor protein, polynucleotide encoding the protein, cell transformed with the polynucleotide and method for suppressing proliferationof cancer cell using the expression vector Abandoned AU2001220255A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR10-2000-0021897A KR100426455B1 (en) 2000-04-25 2000-04-25 Human cancer suppressor gene, protein encoding by same, expression vector containing same, and cell transformed by said vector
KR0021897 2000-04-25
PCT/KR2000/001406 WO2001081387A1 (en) 2000-04-25 2000-12-04 Human cervical cancer suppressor protein, polynucleotide encoding the protein, cell transformed with the polynucleotide and method for suppressing proliferation of cancer cell using the expression vector

Publications (1)

Publication Number Publication Date
AU2001220255A1 true AU2001220255A1 (en) 2001-11-07

Family

ID=36251014

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001220255A Abandoned AU2001220255A1 (en) 2000-04-25 2000-12-04 Human cervical cancer suppressor protein, polynucleotide encoding the protein, cell transformed with the polynucleotide and method for suppressing proliferationof cancer cell using the expression vector

Country Status (11)

Country Link
US (1) US6977296B2 (en)
EP (1) EP1282641B1 (en)
JP (1) JP3749182B2 (en)
KR (1) KR100426455B1 (en)
CN (1) CN1216909C (en)
AT (1) ATE325812T1 (en)
AU (1) AU2001220255A1 (en)
CA (1) CA2405983A1 (en)
DE (1) DE60027928T2 (en)
HK (1) HK1060136A1 (en)
WO (1) WO2001081387A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100426452B1 (en) * 2001-01-02 2004-04-13 김진우 Transgenic mammal containing human protooncogene and kit for diagnosing breast, kidney, ovary or stomach cancer
ATE278796T1 (en) * 2001-04-23 2004-10-15 Amaxa Gmbh BUFFER SOLUTION FOR ELECTROPORATION AND METHOD COMPRISING THE USE OF THE SAME
KR100434591B1 (en) * 2002-04-16 2004-06-04 김진우 Human cancer suppressor gene, protein encoded therein, expression vector containing same, and cell transformed by said vector
KR100664589B1 (en) * 2004-12-28 2007-01-04 김현기 Human cancer suppressor gene protein encoded therein expression vector containing same
EP2099467B1 (en) * 2006-10-03 2017-05-10 University Of Medicine And Dentistry Of New Jersey Atap peptides, nucleic acids encoding the same and associated methods of use
KR101815322B1 (en) * 2010-01-12 2018-01-05 서울대학교산학협력단 Anti-cancer peptide sequences

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR960034413A (en) * 1995-03-24 1996-10-22 권계홍 Apoptosis regulatory genes
AU1873097A (en) * 1996-02-14 1997-09-02 New England Deaconess Hospital Corporation Gene therapy of entothelial cells with anti-apoptotic proteins for transplantation and inflammatory conditions
WO1999061612A1 (en) * 1998-05-28 1999-12-02 Incyte Pharmaceuticals, Inc. Tumor suppressor
CA2296792A1 (en) * 1999-02-26 2000-08-26 Genset S.A. Expressed sequence tags and encoded human proteins

Also Published As

Publication number Publication date
US20040086974A1 (en) 2004-05-06
EP1282641A1 (en) 2003-02-12
US6977296B2 (en) 2005-12-20
DE60027928T2 (en) 2007-01-04
KR100426455B1 (en) 2004-04-13
CA2405983A1 (en) 2001-11-01
CN1451016A (en) 2003-10-22
JP2003534783A (en) 2003-11-25
DE60027928D1 (en) 2006-06-14
EP1282641A4 (en) 2004-05-19
WO2001081387A1 (en) 2001-11-01
CN1216909C (en) 2005-08-31
KR20010097640A (en) 2001-11-08
EP1282641B1 (en) 2006-05-10
HK1060136A1 (en) 2004-07-30
ATE325812T1 (en) 2006-06-15
JP3749182B2 (en) 2006-02-22

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase
TH Corrigenda

Free format text: IN VOL 16, NO 11, PAGE(S) 2339-2354 UNDER THE HEADING APPLICATIONS LAPSED, REFUSED OR WITHDRAWN PLEASE DELETE ALL REFERENCE TO APPLICATION NO. 55774/00, 20255/01, 50505/01, 54986/01, 68896/01, 75634/01 AND 76232/01