MX9700792A - Nuevos polimorfos de diclorhidrato de lesopitron y sus formas hidratadas, procedimientos de preparacion y composiciones que los contienen. - Google Patents

Nuevos polimorfos de diclorhidrato de lesopitron y sus formas hidratadas, procedimientos de preparacion y composiciones que los contienen.

Info

Publication number
MX9700792A
MX9700792A MX9700792A MX9700792A MX9700792A MX 9700792 A MX9700792 A MX 9700792A MX 9700792 A MX9700792 A MX 9700792A MX 9700792 A MX9700792 A MX 9700792A MX 9700792 A MX9700792 A MX 9700792A
Authority
MX
Mexico
Prior art keywords
lesopitron
dichlorohydrate
compositions containing
preparation methods
hydrated forms
Prior art date
Application number
MX9700792A
Other languages
English (en)
Inventor
Pilar Lupon Roses
Jaime Tomas Navarro
Salvadro Puig Torres
Jordi Frigola Constansa
Original Assignee
Esteve Labor Dr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Esteve Labor Dr filed Critical Esteve Labor Dr
Publication of MX9700792A publication Critical patent/MX9700792A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Comprende los nuevos polimorfos I y II de diclorhidrato de Lesopitron caracterizados por sus espectros infrarrojo y defractogramas de Rayos-X. Se obtienen por cristalizacion del diclorhidrato de Lesopitron. Asimismo, comprende las formas I-hidrato y II-hidrato, que se obtienen de los correspondientes polimorfos, que poseen un contenido en agua de 3 al 5% y del 1.5 al 2.5%, respectivamente. Tales productos se utilizan en medicina humana principalmente pro su actividad farmacologica sobre el sistema nervioso central.
MX9700792A 1995-05-31 1996-05-29 Nuevos polimorfos de diclorhidrato de lesopitron y sus formas hidratadas, procedimientos de preparacion y composiciones que los contienen. MX9700792A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES09501086A ES2099031B1 (es) 1995-05-31 1995-05-31 Nuevos polimorfos de diclorhidrato de lesopitron y sus formas hidratadas, procedimientos de preparacion y composiciones que los contienen.
PCT/ES1996/000121 WO1996038439A1 (es) 1995-05-31 1996-05-29 Nuevos polimorfos de diclorhidrato de lesopitron y sus formas hidratadas, procedimientos de preparacion y composiciones que los contienen

Publications (1)

Publication Number Publication Date
MX9700792A true MX9700792A (es) 1997-05-31

Family

ID=8290585

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9700792A MX9700792A (es) 1995-05-31 1996-05-29 Nuevos polimorfos de diclorhidrato de lesopitron y sus formas hidratadas, procedimientos de preparacion y composiciones que los contienen.

Country Status (29)

Country Link
US (1) US5872125A (es)
EP (1) EP0771798A1 (es)
JP (1) JPH10503532A (es)
CN (1) CN1076020C (es)
AR (1) AR003952A1 (es)
AU (1) AU699210B2 (es)
BG (1) BG62966B1 (es)
CA (1) CA2196425A1 (es)
CO (1) CO4700461A1 (es)
CZ (1) CZ24797A3 (es)
EE (1) EE9700067A (es)
ES (1) ES2099031B1 (es)
GE (1) GEP20002241B (es)
HU (1) HUP9700284A3 (es)
IL (1) IL118494A0 (es)
IN (1) IN186820B (es)
IS (1) IS4420A (es)
MA (1) MA23883A1 (es)
MX (1) MX9700792A (es)
NO (1) NO310073B1 (es)
NZ (1) NZ308110A (es)
PL (1) PL318280A1 (es)
RU (1) RU2178789C2 (es)
SK (1) SK12697A3 (es)
TR (1) TR199600455A2 (es)
UY (1) UY24241A1 (es)
WO (1) WO1996038439A1 (es)
YU (1) YU32396A (es)
ZA (1) ZA964139B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6869970B2 (en) 2002-02-04 2005-03-22 Novartis Ag Crystalline salt forms of valsartan

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2642759B1 (fr) * 1989-02-09 1991-05-17 Laboratorios Esteve Sa Derives de pyrimidyl-piperazinyl-alkyl azoles avec activite anxiolytique et/ou tranquillisante
FR2654621B1 (fr) * 1989-11-22 1994-09-23 Esteve Labor Dr Inhibition du syndrome d'abstinence.
FR2672052B1 (fr) * 1991-01-28 1995-05-24 Esteve Labor Dr Derives d'aryl (ou heteroaryl)-piperazinyl-alkyl-azoles, leur preparation et leur application en tant que medicaments.
FR2671972B1 (fr) * 1991-01-25 1995-03-03 Esteve Labor Dr Utilisation de derives 1-h-azole-(omega-(4-(2-pyrimidinyl)-1-piperazinyl)-alkyl) pour la preparation de medicaments destines au traitement des troubles des fonctions cognitives.
FR2673628B1 (fr) * 1991-03-07 1993-07-09 Esteve Labor Dr Procede de preparation de derives d'aryl (ou heteroaryl)-piperazinyl-butyl-azoles.
FR2705098B1 (fr) * 1993-05-10 1995-08-04 Esteve Labor Dr Procédé de préparation de 2-{4-[4-(chloro-1-pyrazolyl)butyl]1-pipérazinyl}pyrimidine (Lesopitron) .

Also Published As

Publication number Publication date
GEP20002241B (en) 2000-09-25
PL318280A1 (en) 1997-06-09
IS4420A (is) 1997-01-29
CA2196425A1 (en) 1996-12-05
WO1996038439A1 (es) 1996-12-05
AU5765096A (en) 1996-12-18
UY24241A1 (es) 1996-06-14
HUP9700284A3 (en) 1998-01-28
CN1076020C (zh) 2001-12-12
IL118494A0 (en) 1996-09-12
CZ24797A3 (en) 1997-05-14
CN1158128A (zh) 1997-08-27
AU699210B2 (en) 1998-11-26
RU2178789C2 (ru) 2002-01-27
EE9700067A (et) 1997-10-15
BG101176A (en) 1997-08-29
HU9700284D0 (en) 1997-04-28
AR003952A1 (es) 1998-09-30
NO970392D0 (no) 1997-01-29
EP0771798A1 (en) 1997-05-07
BG62966B1 (bg) 2000-12-29
IN186820B (es) 2001-11-17
ES2099031A1 (es) 1997-05-01
HUP9700284A2 (en) 1997-11-28
NZ308110A (en) 1997-08-22
MA23883A1 (fr) 1996-12-31
NO310073B1 (no) 2001-05-14
CO4700461A1 (es) 1998-12-29
ZA964139B (en) 1997-02-06
TR199600455A2 (tr) 1996-12-21
ES2099031B1 (es) 1997-12-01
US5872125A (en) 1999-02-16
JPH10503532A (ja) 1998-03-31
YU32396A (sh) 1999-07-28
NO970392L (no) 1997-04-01
SK12697A3 (en) 1997-07-09

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