MX9606493A - Derivado de triterpeno y composicion medicinal. - Google Patents

Derivado de triterpeno y composicion medicinal.

Info

Publication number
MX9606493A
MX9606493A MX9606493A MX9606493A MX9606493A MX 9606493 A MX9606493 A MX 9606493A MX 9606493 A MX9606493 A MX 9606493A MX 9606493 A MX9606493 A MX 9606493A MX 9606493 A MX9606493 A MX 9606493A
Authority
MX
Mexico
Prior art keywords
optionally substituted
represent
medicinal composition
independently hydrogen
alkynyl
Prior art date
Application number
MX9606493A
Other languages
English (en)
Inventor
Tadaaki Ohgi
Hiroto Yoshifusa
Kazuhisa Kandori
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Publication of MX9606493A publication Critical patent/MX9606493A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)

Abstract

La invencion esta compuesta de un derivado de hederagenina de la siguiente formula o una sal farmacéuticamente aceptable del mismo, y una composicion farmacéutica que comprende este compuesto como un ingrediente activo I: (en donde R1 representa OR11 o NR11R12, R11 y R12 pueden ser los mismos o diferentes y cada uno representa hidrogeno, alquilo que puede estar substituido, cicloalquilo que puede estar sustituido, alquenilo que puede estar substituido, alquinilo que puede estar substituido, arilo que puede estar substituido, o un grupo heteroaromático que puede estar substituido. R2 y R3 pueden ser el mismo o diferentes, y cada uno representa hidrogeno, alquilo que puede estar substituido, cicloalquilo que puede estar substituido, alquenilo que puede estar substituido, alquinilo que puede estar substituido, acilo que puede estar substituido, monoalquilcarbamoilo que puede estar substituido, dialquilcarbamoilo que puede estar substituido, alcoxicarbonilo que puede estar substituido, o R2 y R3, tomados conjuntamente, representan carbonilo. La composicion farmacéutica de la invencion es efectiva para la terapia de la nefritis.
MX9606493A 1994-06-24 1995-06-22 Derivado de triterpeno y composicion medicinal. MX9606493A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP14270894 1994-06-24
PCT/JP1995/001249 WO1996000236A1 (fr) 1994-06-24 1995-06-22 Derive du triterpene et preparation medicinale associee

Publications (1)

Publication Number Publication Date
MX9606493A true MX9606493A (es) 1997-03-29

Family

ID=15321726

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9606493A MX9606493A (es) 1994-06-24 1995-06-22 Derivado de triterpeno y composicion medicinal.

Country Status (12)

Country Link
US (1) US5885992A (es)
EP (1) EP0767177A4 (es)
CN (1) CN1151165A (es)
AU (1) AU2753095A (es)
BR (1) BR9508110A (es)
CA (1) CA2193679A1 (es)
FI (1) FI965193A (es)
HU (1) HUT76333A (es)
MX (1) MX9606493A (es)
NO (1) NO965444L (es)
TW (1) TW403759B (es)
WO (1) WO1996000236A1 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19655276B4 (de) * 1996-04-25 2008-04-30 Lucas Industries Plc, Solihull Elektrohydraulische Bremsanlage
US6124362A (en) * 1998-07-17 2000-09-26 The Procter & Gamble Company Method for regulating hair growth
US9387168B2 (en) 1999-09-20 2016-07-12 Jack Barreca Chewing gum with tomatidine
WO2001064709A1 (en) * 2000-02-29 2001-09-07 Dabur Research Foundation A novel process for manufacturing betulinic acid from ziziphus jujuba
GB0128071D0 (en) * 2001-11-22 2002-01-16 Cyclacel Ltd Medicament
EP1556062B1 (en) * 2002-08-28 2009-12-23 Lupin Limited Herbal extract comprising a mixture of saponins obtained from sapindus trifoliatus for anticonvulsant activity
US7691289B2 (en) * 2003-02-25 2010-04-06 Emory University Compositions, materials incorporating the compositions, and methods of using the compositions, and methods of using the compositions and materials
ES2527857T3 (es) 2003-05-08 2015-01-30 Tepha, Inc. Tejidos y fibras médicas de polihidroxialcanoato
CN104688745B (zh) * 2010-05-20 2019-11-12 爱荷华大学研究基金会 用于抑制肌萎缩的方法
US11090313B2 (en) 2010-05-20 2021-08-17 University Of Iowa Research Foundation Methods for inhibiting muscle atrophy
CN103391776B (zh) * 2010-07-16 2023-11-28 太平洋艾瑞有限公司 可治疗癌症和其它疾病的新化合物
US9295664B2 (en) 2011-06-06 2016-03-29 University Of Iowa Research Foundation Methods for lowering blood glucose
WO2013028307A1 (en) * 2011-08-24 2013-02-28 Amyris, Inc. Derivatives of hydrocarbon terpenes
CN102659905B (zh) * 2012-05-21 2014-07-30 广州博济医药生物技术股份有限公司 一种常春藤皂苷元衍生物及其制备方法和应用
CN102675406A (zh) * 2012-06-04 2012-09-19 福州大学 抗肿瘤活性的熊果酸含氮杂环类结构修饰物及其制备方法
WO2016193309A1 (en) * 2015-06-01 2016-12-08 Dsm Ip Assets B.V. New bis esters of ivy sapogenins for ruminants

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06345650A (ja) * 1993-06-14 1994-12-20 Suntory Ltd ヘデラゲニン化合物を有効成分とする骨疾患の予防及び治療剤

Also Published As

Publication number Publication date
NO965444L (no) 1997-02-24
FI965193A0 (fi) 1996-12-23
WO1996000236A1 (fr) 1996-01-04
BR9508110A (pt) 1997-08-12
EP0767177A4 (en) 1998-09-30
HUT76333A (en) 1997-08-28
HU9603487D0 (en) 1997-02-28
EP0767177A1 (en) 1997-04-09
CN1151165A (zh) 1997-06-04
US5885992A (en) 1999-03-23
TW403759B (en) 2000-09-01
AU2753095A (en) 1996-01-19
NO965444D0 (no) 1996-12-18
CA2193679A1 (en) 1996-01-04
FI965193A (fi) 1996-12-23

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