MX9401415A - Ligandos 5-ht1a. - Google Patents

Ligandos 5-ht1a.

Info

Publication number
MX9401415A
MX9401415A MX9401415A MX9401415A MX9401415A MX 9401415 A MX9401415 A MX 9401415A MX 9401415 A MX9401415 A MX 9401415A MX 9401415 A MX9401415 A MX 9401415A MX 9401415 A MX9401415 A MX 9401415A
Authority
MX
Mexico
Prior art keywords
ht1a
leagues
radiolabelled
pet
studies
Prior art date
Application number
MX9401415A
Other languages
English (en)
Inventor
Ian Anthony Cliffe
Allan Fletcher
Alan Chapman White
Original Assignee
Wyeth John & Brother Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth John & Brother Ltd filed Critical Wyeth John & Brother Ltd
Publication of MX9401415A publication Critical patent/MX9401415A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0468—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0459—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Se describen antagonistas de 5-HT1A selectivos, radiomarcados con H3 o C11 que son ligandos radiomarcados útiles, por ejemplo, en procedimientos de selección farmacológica y en estudios de tomografía de emisión de positrones (PET).
MX9401415A 1993-02-26 1994-02-24 Ligandos 5-ht1a. MX9401415A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939303968A GB9303968D0 (en) 1993-02-26 1993-02-26 5-ht1a ligands

Publications (1)

Publication Number Publication Date
MX9401415A true MX9401415A (es) 1994-08-31

Family

ID=10731124

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9401415A MX9401415A (es) 1993-02-26 1994-02-24 Ligandos 5-ht1a.

Country Status (12)

Country Link
US (1) US6056942A (es)
EP (1) EP0686047B1 (es)
AT (1) ATE188614T1 (es)
AU (1) AU6009694A (es)
DE (1) DE69422611T2 (es)
DK (1) DK0686047T3 (es)
ES (1) ES2141819T3 (es)
GB (1) GB9303968D0 (es)
GR (1) GR3032479T3 (es)
MX (1) MX9401415A (es)
PT (1) PT686047E (es)
WO (1) WO1994019026A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9413772D0 (en) * 1994-07-08 1994-08-24 Wyeth John & Brother Ltd 5-HT1A ligands
US6835728B2 (en) 2000-01-19 2004-12-28 Akzo Nobel N.V. Drug combination for the treatment of depression and related disorders comprising mirtazapine
BRPI0114147B1 (pt) 2001-08-09 2017-06-27 Laboratorios Miret, S.A. Cosmetic or dermatological composition in the form of an emulsion understanding cationic surfaces
CA2455983C (en) * 2001-08-09 2010-06-01 Joan Baptista Urgell Beltran Preservative systems and their use in cosmetic preparations
CA2464388C (en) 2001-10-25 2010-07-06 Laboratorios Miret, S.A. Use of cationic preservative in food products
ATE408702T1 (de) 2002-02-01 2008-10-15 Miret Lab Enzymatische synthese von n(alpha)-acyl-l- argininestern
US7662417B2 (en) 2002-05-08 2010-02-16 Laboratorios Miret, S.A. Preservatives and protective systems
JP4730760B2 (ja) * 2004-05-25 2011-07-20 住友重機械工業株式会社 Ｒｉ標識化合物合成システム
US7731940B2 (en) 2006-01-25 2010-06-08 The Regents Of The University Of California Compositions and methods related to serotonin 5-HT1A receptors
US20130064770A1 (en) 2010-05-28 2013-03-14 Ge Healthcare Limited Radiolabeled compounds and methods thereof
GB201112987D0 (en) 2011-07-28 2011-09-14 Ge Healthcare Ltd Novel compound
GB201116359D0 (en) * 2011-09-22 2011-11-02 Ge Healthcare Ltd Novel synthesis method

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69033100T2 (de) * 1989-04-22 2000-01-05 Wyeth John & Brother Ltd Piperazin-Derivate
HU221315B1 (en) * 1989-04-22 2002-09-28 Wyeth John & Brother Ltd Alkyl-substituted piperazine derivatives, pharmaceutical compositions containing them, and process for producing them
US4994258A (en) * 1990-03-05 1991-02-19 Merck & Co., Inc. Gamma emitting, CCK-A antagonists for pancreatic imaging
GB9022820D0 (en) * 1990-10-19 1990-12-05 Wyeth John & Brother Ltd Piperazine derivatives
AU645681B2 (en) * 1991-05-02 1994-01-20 John Wyeth & Brother Limited Piperazine derivatives

Also Published As

Publication number Publication date
EP0686047B1 (en) 2000-01-12
DK0686047T3 (da) 2000-04-25
AU6009694A (en) 1994-09-14
ATE188614T1 (de) 2000-01-15
PT686047E (pt) 2000-06-30
EP0686047A1 (en) 1995-12-13
GB9303968D0 (en) 1993-04-14
DE69422611T2 (de) 2008-10-09
ES2141819T3 (es) 2000-04-01
GR3032479T3 (en) 2000-05-31
US6056942A (en) 2000-05-02
WO1994019026A1 (en) 1994-09-01
DE69422611D1 (de) 2000-02-17

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