MX9401295A - Fosfonatos sustituidos, los procedimientos para supreparacion y composiciones farmaceuticas que los contienen. - Google Patents
Fosfonatos sustituidos, los procedimientos para supreparacion y composiciones farmaceuticas que los contienen.Info
- Publication number
- MX9401295A MX9401295A MX9401295A MX9401295A MX9401295A MX 9401295 A MX9401295 A MX 9401295A MX 9401295 A MX9401295 A MX 9401295A MX 9401295 A MX9401295 A MX 9401295A MX 9401295 A MX9401295 A MX 9401295A
- Authority
- MX
- Mexico
- Prior art keywords
- pharmaceutical compositions
- supreparation
- procedures
- contain
- substituted phosphonates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
- C07F9/657163—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom
- C07F9/657181—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom the ring phosphorus atom and, at least, one ring oxygen atom being part of a (thio)phosphonic acid derivative
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4015—Esters of acyclic unsaturated acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4056—Esters of arylalkanephosphonic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4056—Esters of arylalkanephosphonic acids
- C07F9/4059—Compounds containing the structure (RY)2P(=X)-(CH2)n-C(=O)-(CH2)m-Ar, (X, Y = O, S, Se; n>=1, m>=0)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/44—Amides thereof
- C07F9/4403—Amides thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4411—Amides of acyclic unsaturated acids
Abstract
Esta invención se refiere a fosfonatos novedosos sustituidos con un porción dialquilfenol, y a los procedimientos para su preparación. Se refiere adicionalmente a las composiciones farmacéuticas que contienen estos compuestos y a su uso terapéutico en enfermedades en las cuales se han implicado radicales oxígeno reactivo y, más específicamente, en el tratamiento de la ateroesclerosis.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH52193 | 1993-02-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9401295A true MX9401295A (es) | 1994-08-31 |
Family
ID=4188911
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9401295A MX9401295A (es) | 1993-02-19 | 1994-02-18 | Fosfonatos sustituidos, los procedimientos para supreparacion y composiciones farmaceuticas que los contienen. |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0638084A1 (es) |
JP (1) | JPH07506121A (es) |
CN (1) | CN1106611A (es) |
AU (1) | AU6205294A (es) |
CA (1) | CA2118409A1 (es) |
MX (1) | MX9401295A (es) |
WO (1) | WO1994019358A1 (es) |
ZA (1) | ZA941088B (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4433244A1 (de) * | 1994-09-19 | 1996-03-28 | Hoechst Ag | Aminomethylphosphon- und Aminomethylphosphinsäure-Derivate und deren Verwendung zur Behandlung von degenerativen Gelenkserkrankungen |
DE19502209A1 (de) * | 1995-01-25 | 1996-08-01 | Hoechst Ag | Phosphonoessigsäure-Derivate und deren Verwendung zur Behandlung von degenerativen Gelenkserkrankungen |
JP3588734B2 (ja) * | 1996-07-26 | 2004-11-17 | コニカミノルタホールディングス株式会社 | 電子写真感光体 |
AU2003272513A1 (en) * | 2002-09-19 | 2004-04-08 | Ilex Oncology Research, Sarl | Substituted ketophosphonate inhibitors of tumor cell proliferation |
EP1551418A4 (en) * | 2002-09-19 | 2006-05-03 | Ilex Oncology Res Sarl | SUBSTITUTED KETOPHOSPHONATE COMPOUNDS WITH BONE ANABOLIC EFFECT |
FR2876104B1 (fr) * | 2004-10-04 | 2007-02-23 | Centre Nat Rech Scient | Composes fluorophosphonocinnamiques, systhese et aplications |
GB0613518D0 (en) * | 2006-07-06 | 2006-08-16 | Phytopharm Plc | Chemical compounds |
JP5559186B2 (ja) * | 2008-11-13 | 2014-07-23 | ビーエーエスエフ ソシエタス・ヨーロピア | ホスホノ基を含有するベンジリデン化合物 |
EP2270021A1 (en) * | 2009-06-18 | 2011-01-05 | Centre National de la Recherche Scientifique | Phosphonates synthons for the synthesis of phosphonates derivatives showing better bioavailability |
CN109154016B (zh) * | 2017-12-29 | 2021-11-16 | 邦泰生物工程(深圳)有限公司 | 一种化学-酶法制备熊去氧胆酸的方法 |
CN108794559A (zh) * | 2018-07-31 | 2018-11-13 | 重庆波克底科技开发有限责任公司 | 一种以猪去氧胆酸为原料合成石胆酸的方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2024030A1 (de) * | 1970-05-16 | 1971-12-02 | Deutsche Advance Produktion GmbH, 6141 Lautern | 2,6-Dialkylphenole |
JPS5921889B2 (ja) * | 1975-06-02 | 1984-05-23 | 帝人株式会社 | ポリエステルの製造方法 |
JPS5782828A (en) * | 1980-11-11 | 1982-05-24 | Canon Inc | Heat developing photosensitive material |
DE3362618D1 (en) * | 1982-10-07 | 1986-04-24 | Ciba Geigy Ag | Phenols and their preparation |
CH675422A5 (es) * | 1988-03-31 | 1990-09-28 | Symphar Sa | |
JPH0377894A (ja) * | 1989-08-18 | 1991-04-03 | Toray Ind Inc | メチレンジホスホン酸化合物 |
US5300687A (en) * | 1991-07-18 | 1994-04-05 | Ortho Pharmaceutical Corporation | Trifluoromethylbenzylphosphonates useful in treating osteoporosis |
-
1994
- 1994-02-17 ZA ZA941088A patent/ZA941088B/xx unknown
- 1994-02-18 MX MX9401295A patent/MX9401295A/es unknown
- 1994-02-21 CA CA002118409A patent/CA2118409A1/en not_active Abandoned
- 1994-02-21 AU AU62052/94A patent/AU6205294A/en not_active Abandoned
- 1994-02-21 EP EP94909033A patent/EP0638084A1/en not_active Withdrawn
- 1994-02-21 JP JP6518667A patent/JPH07506121A/ja active Pending
- 1994-02-21 CN CN94190122A patent/CN1106611A/zh active Pending
- 1994-02-21 WO PCT/EP1994/000520 patent/WO1994019358A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
JPH07506121A (ja) | 1995-07-06 |
AU6205294A (en) | 1994-09-14 |
EP0638084A1 (en) | 1995-02-15 |
ZA941088B (en) | 1995-09-27 |
CN1106611A (zh) | 1995-08-09 |
CA2118409A1 (en) | 1994-09-01 |
WO1994019358A1 (en) | 1994-09-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2183937T3 (es) | Inhibidores de la adhesion celular. | |
GT199700015A (es) | Inhibidores de metaloproteinasa, composiciones farmaceuticas que las contienen y su uso farmaceutico y metodosyeficazproducto intermedio para su preparacion. | |
GT200500007A (es) | [1,8]naftiridin-2-onas y compuestos relacionados para el tratamiento de la esquizofrenia. | |
CU23393A3 (es) | Compuestos inhibidores de la raf kinasa y composiciones farmacéuticas que los contienen | |
ES2181614T3 (es) | Sulfonilfenilheterociclos sustituidos como inhibidores de ciclooxigenasa-2 y 5-lipoxigenasa. | |
PA8462401A1 (es) | Derivados de la tienopirimidina y de la tienopiridina utiles como agentes anticancerigenos | |
ES2165441T3 (es) | Inhibidores de calpaina y/o catepsina b oxazolidin sustituidos. | |
HN2002000154A (es) | Azaindoles | |
UY24256A1 (es) | Anticuerpos monoclonales de mono especificos para anticuerpos humanos b 7.1 y/o b7.2, formas primatizadas de los mis- mos, composiciones farmaceuticas que los contienen y uso de los mismos como inmunosupresores | |
ECSP941104A (es) | Derivados de 2,6 diaminopurina, procedimiento para su preparacion y composiciones farmaceuticas que los contienen | |
AR029383A1 (es) | Moleculas pequenas, los intermediarios para su sintesis, las composiciones farmaceuticas que las contienen y su uso para preparar un medicamento destinado al tratamiento o la profilaxis de enfermedades inflamatorias o mediadas por celulas inmunes | |
ES2196377T3 (es) | Derivados de naftiridina. | |
BR9911488A (pt) | Composto, uso do mesmo, composição farmacêutica, e, processos para tratamento ou de profilaxia de doenças inflamatórias, e para a preparação de um composto | |
GT199900146A (es) | Derivados de 4,4-biarilpiperidina. | |
ES2139959T3 (es) | Derivados de estilbeno utiles como inhibidores de la ciclooxigenasa-2. | |
GT199700089A (es) | Derivados 6.6 o 6.7 -biciclicos sustituidos que contienen pirido o pirimido. | |
ECSP055609A (es) | "Uso de inhibidores de la IkB-quinasa para el tratamiento del dolor" | |
ES2115237T3 (es) | Fenil heterociclos como inhibidores de la ciclooxigenasa-2. | |
AR012294A1 (es) | Derivados de sulfonamida, un procedimiento para su preparacion, composiciones farmaceuticas que los contienen, uso de dichos derivados para lapreparacion de un medicamento. | |
MX9401295A (es) | Fosfonatos sustituidos, los procedimientos para supreparacion y composiciones farmaceuticas que los contienen. | |
ITMI931649A1 (it) | Derivati dell'acido 2-ammino-4-fenil-4-osso butirrico | |
ES2066239T3 (es) | Complejos fosfolipidicos de bilobalido, sus aplicaciones y formulados que los contienen. | |
ES2076595T3 (es) | Derivados de amidinofenilalanina, procedimiento para su preparacion, su empleo y agentes que los contienen. | |
DK0417003T3 (da) | Anvendelse af antiprogestomimetiske forbindelser til fremme af ovulation | |
ES2150461T3 (es) | Derivados de amidinofenilalanina, proceso para su preparacion, su empleo y agentes que los contienen como anticoagulantes. |