MX9304582A - Derivados del acido quinolilmetoxi-fenilacetico sustituidos en la posicion 2, procedimiento para su obtencion y medicamentos que los contienen. - Google Patents

Derivados del acido quinolilmetoxi-fenilacetico sustituidos en la posicion 2, procedimiento para su obtencion y medicamentos que los contienen.

Info

Publication number
MX9304582A
MX9304582A MX9304582A MX9304582A MX9304582A MX 9304582 A MX9304582 A MX 9304582A MX 9304582 A MX9304582 A MX 9304582A MX 9304582 A MX9304582 A MX 9304582A MX 9304582 A MX9304582 A MX 9304582A
Authority
MX
Mexico
Prior art keywords
derivatives
quinolylmetoxy
procedure
obtaining
phenylacetic acid
Prior art date
Application number
MX9304582A
Other languages
English (en)
Inventor
Romanis Fruchtmann
Reiner Muller-Peddinghaus
Armin Hatzelmann
Michael Matzke
Klaus-Helmut Mohrs
Siegfried Raddatz
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of MX9304582A publication Critical patent/MX9304582A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Sus derivados del ácido quinolilmetoxi-fenilacético sustituído en 2, se obtienen mediante transformación de los correspondientes fenoles sustituídos con halogenuros de quinolilmetilo o mediante transformación de fenoles no sustituídos con halogenuros de quinolilmetilo y posterior alquilación. Los derivados del ácido quinolilmetoxifenil-acético sustituído en 2, pueden emplearse como sustancia activa en medicamentos.
MX9304582A 1992-08-11 1993-07-29 Derivados del acido quinolilmetoxi-fenilacetico sustituidos en la posicion 2, procedimiento para su obtencion y medicamentos que los contienen. MX9304582A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4226519A DE4226519A1 (de) 1992-08-11 1992-08-11 3-Substituierte Chinolylmethoxy-phenylessigsäurederivate

Publications (1)

Publication Number Publication Date
MX9304582A true MX9304582A (es) 1994-02-28

Family

ID=6465285

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9304582A MX9304582A (es) 1992-08-11 1993-07-29 Derivados del acido quinolilmetoxi-fenilacetico sustituidos en la posicion 2, procedimiento para su obtencion y medicamentos que los contienen.

Country Status (22)

Country Link
US (1) US5597833A (es)
EP (1) EP0582908B1 (es)
JP (1) JPH06157463A (es)
KR (1) KR940003936A (es)
CN (1) CN1087337A (es)
AT (1) ATE166645T1 (es)
AU (1) AU668574B2 (es)
CA (1) CA2103521A1 (es)
CZ (1) CZ151193A3 (es)
DE (2) DE4226519A1 (es)
DK (1) DK0582908T3 (es)
ES (1) ES2117070T3 (es)
FI (1) FI933512A7 (es)
HU (1) HUT70041A (es)
IL (1) IL106622A (es)
MX (1) MX9304582A (es)
MY (1) MY108877A (es)
NO (1) NO179513C (es)
NZ (1) NZ248343A (es)
PL (1) PL300026A1 (es)
SK (1) SK86593A3 (es)
ZA (1) ZA935795B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4443892A1 (de) * 1994-12-09 1996-06-13 Bayer Ag 4-(Chinolin-2-yl-methoxy)-phenyl-essigsäurederivate
DE4443891A1 (de) 1994-12-09 1996-06-13 Bayer Ag Heterocyclisch substituierte Oxy-phenyl-(phenyl)glycinolamide
US6069151A (en) * 1996-11-06 2000-05-30 Darwin Discovery, Ltd. Quinolines and their therapeutic use
GB2356139A (en) * 1999-11-15 2001-05-16 Bayer Ag Use of substituted (quinolin-2-yl-methoxy)phenyl-acyl-sulphonamides and cyanamides for the treatment of diseases
EP2284157A1 (en) 2003-12-12 2011-02-16 Wyeth Quinolines useful in treating cardiovascular disease
CA2617969A1 (en) * 2005-08-10 2007-02-15 Takeda Pharmaceutical Company Limited Therapeutic agent for diabetes
JP2010511632A (ja) 2006-11-30 2010-04-15 アミラ ファーマシューティカルス，インコーポレーテッド ５−リポキシゲナーゼ活性化タンパク質インヒビターおよび一酸化窒素モジュレーターを含んでいる組成物および治療法
ES2878405T3 (es) 2014-02-04 2021-11-18 Bioscience Pharma Partners Llc Uso de inhibidores de flap para reducir la lesión mediada por neuroinflamación en el sistema nervioso central

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3814504A1 (de) * 1988-04-29 1989-11-09 Bayer Ag (alpha)-substituierte 4-(chinolin-2-yl-methoxy)phenylessigsaeuren und -ester, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DE3900261A1 (de) * 1988-05-31 1989-12-07 Bayer Ag Substituierte 4-(chinolin-2-yl-methoxy) phenyl-essigsaeure-derivate
US5232916A (en) * 1988-06-27 1993-08-03 Merck Frosst Canada, Inc. Quinoline ether alkanoic acids
DE3916663A1 (de) * 1989-05-23 1990-11-29 Bayer Ag Substituierte (chinolin-2-yl-methoxy)phenyl-acyl-sulfonamide und -cyanamide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
JPH0742488Y2 (ja) * 1989-05-23 1995-10-04 川崎重工業株式会社 移動床型脱じん・反応装置
DE3927369A1 (de) * 1989-08-19 1991-02-21 Bayer Ag Substituierte n-(chinolin-2-yl-methoxy)benzyl-sulfonyl-harnstoffe
DE3927930A1 (de) * 1989-08-24 1991-02-28 Bayer Ag Cyclisch substituierte (chinolin-2-yl-methoxy)phenyl-essig-saeure-derivate
DE3927931A1 (de) * 1989-08-24 1991-02-28 Bayer Ag Disubstituierte (chinolin-2-yl-methoxy)phenylessigsaeure-derivate
US5304563A (en) * 1991-02-22 1994-04-19 Bayer Aktiengesellschaft 2-substituted quinolines, and their use in medicaments
DE4125270A1 (de) * 1991-07-31 1993-02-04 Bayer Ag Chinolin-2-yl-methoxybenzylhydroxyharnstoffe
DE4139749A1 (de) * 1991-12-03 1993-06-09 Bayer Ag, 5090 Leverkusen, De Chinolylmethoxyphenyl-essigsaeureamide
US5358955A (en) * 1992-10-30 1994-10-25 Abbott Laboratories Aryl and heteroarylmethoxyphenyl inhibitors of leukotriene biosynthesis

Also Published As

Publication number Publication date
NO932709L (no) 1994-02-14
EP0582908B1 (de) 1998-05-27
AU4425393A (en) 1994-02-17
ATE166645T1 (de) 1998-06-15
IL106622A (en) 1997-02-18
NO179513B (no) 1996-07-15
HUT70041A (en) 1995-09-28
IL106622A0 (en) 1993-12-08
CZ151193A3 (en) 1994-03-16
NZ248343A (en) 1995-03-28
KR940003936A (ko) 1994-03-14
CN1087337A (zh) 1994-06-01
AU668574B2 (en) 1996-05-09
PL300026A1 (en) 1994-03-21
HU9302313D0 (en) 1993-10-28
MY108877A (en) 1996-11-30
JPH06157463A (ja) 1994-06-03
EP0582908A1 (de) 1994-02-16
FI933512A7 (fi) 1994-02-12
NO932709D0 (no) 1993-07-27
NO179513C (no) 1996-10-23
FI933512A0 (fi) 1993-08-09
DK0582908T3 (da) 1999-01-18
CA2103521A1 (en) 1994-02-12
US5597833A (en) 1997-01-28
DE4226519A1 (de) 1994-02-17
DE59308603D1 (de) 1998-07-02
ZA935795B (en) 1994-03-07
ES2117070T3 (es) 1998-08-01
SK86593A3 (en) 1994-06-08

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