MX9302804A - Molecula de arn de respuesta. - Google Patents
Molecula de arn de respuesta.Info
- Publication number
- MX9302804A MX9302804A MX9302804A MX9302804A MX9302804A MX 9302804 A MX9302804 A MX 9302804A MX 9302804 A MX9302804 A MX 9302804A MX 9302804 A MX9302804 A MX 9302804A MX 9302804 A MX9302804 A MX 9302804A
- Authority
- MX
- Mexico
- Prior art keywords
- region
- nucleic acid
- inhibitory
- protein
- rna molecule
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
- C12N15/8283—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for virus resistance
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
- C12N2310/111—Antisense spanning the whole gene, or a large part of it
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/12—Type of nucleic acid catalytic nucleic acids, e.g. ribozymes
- C12N2310/124—Type of nucleic acid catalytic nucleic acids, e.g. ribozymes based on group I or II introns
- C12N2310/1241—Tetrahymena
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/12—Type of nucleic acid catalytic nucleic acids, e.g. ribozymes
- C12N2310/127—DNAzymes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/32—Chemical structure of the sugar
- C12N2310/321—2'-O-R Modification
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Cell Biology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
La invención caracteriza a una molécula de ARN de respuesta, la cual codifica en una o más regiones de codificación de la proteína, un polipéptido y la cual incluye un dominio regulador, una región de sustrato y una secuencia de reconocimiento de ribosoma. Esta molécula de ARN de respuesta tiene una región inhibidora en el dominio regulador, el cual dominio regulador es complementario a una región sustrato de la molécula de ARN de respuesta y a una región anti-inhibidora de un ácido nucleico de señal de tal manera que, en ausencia del ácido nucleico de señal, las regiones inhibidoras y de sustrato forman un dominio de bases apareadas, la formación del cual reduce el nivel de traducción de una de las regiones que codifican para la proteína en la molécula de ARN de respuesta, comparada con el nivel de traducción de una región que codifica para la proteína observada en presencia del ácido nucleico de señal. La región anti-inhibidora del ácido nucleico de señal es complementaria en la secuencia con la región inhibidora de la molécula de ARN de respuesta, de tal manera que cuando la región anti-inhibidora está apareada en las bases con la región inhibidora, la traducción de una región de codificación de la proteína del ARN de respuesta está aumentada comparada con el nivel de traducción de esa región que codifica para la proteína, observada en ausencia del ácido nucleico de señal. El ácido nucleico de señal comprende parte del ácido nucleico de un organismo que infecta a la célula vegetal.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US88310792A | 1992-05-14 | 1992-05-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX9302804A true MX9302804A (es) | 1994-04-29 |
Family
ID=25382000
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX9302804A MX9302804A (es) | 1992-05-14 | 1993-05-13 | Molecula de arn de respuesta. |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0641384A4 (es) |
| JP (1) | JPH07507931A (es) |
| AU (1) | AU4234293A (es) |
| CA (1) | CA2135643A1 (es) |
| MX (1) | MX9302804A (es) |
| WO (1) | WO1993023532A1 (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU703644B2 (en) * | 1994-05-11 | 1999-03-25 | Plant Bioscience Limited | Method of introducing pathogen resistance in plants |
| US5712096A (en) * | 1994-08-23 | 1998-01-27 | University Of Massachusetts Medical Center | Oligoribonucleotide assays for novel antibiotics |
| US6235974B1 (en) | 1996-12-05 | 2001-05-22 | Cornell Research Foundation, Inc. | Hypersensitive response induced resistance in plants by seed treatment with a hypersensitive response elicitor |
| US6998515B1 (en) | 1997-01-27 | 2006-02-14 | Cornell Research Foundation, Inc. | Use of a nucleic acid encoding a hypersensitive response elicitor polypeptide to enhance growth in plants |
| US6277814B1 (en) | 1997-01-27 | 2001-08-21 | Cornell Research Foundation, Inc. | Enhancement of growth in plants |
| PL337094A1 (en) * | 1997-05-30 | 2000-07-31 | Cornell Res Foundation Inc | Fragments causing a hypersensitive reaction and their applications |
| US6262018B1 (en) | 1997-08-06 | 2001-07-17 | Cornell Research Foundation, Inc. | Hypersensitive response elicitor from Erwinia amylovora and its use |
| US6172184B1 (en) * | 1997-08-06 | 2001-01-09 | Cornell Research Foundation, Inc. | Hypersensitive response elicitor from Pseudomonas syringae and its use |
| US6228644B1 (en) | 1997-08-06 | 2001-05-08 | Cornell Research Foundation, Inc. | Hypersensitive response elicitor from Erwinia amylovora, its use, and encoding gene |
| US6858707B1 (en) | 1998-10-05 | 2005-02-22 | Eden Bioscience Corporation | Hypersensitive response elicitor fragments which are active but do not elicit a hypersensitive response |
| US6960705B2 (en) | 1998-10-05 | 2005-11-01 | Eden Bioscience Corporation | Nucleic acid encoding a hypersensitive response elicitor from Xanthomonas campestris |
| US6624139B1 (en) | 1998-11-05 | 2003-09-23 | Eden Bioscience Corporation | Hypersensitive response elicitor-induced stress resistance |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8601680D0 (en) * | 1986-01-23 | 1986-02-26 | Agricultural Genetics Co | Modification of plant viruses |
| ES2165345T3 (es) * | 1987-07-10 | 2002-03-16 | Syngenta Participations Ag | Resistencia virica inducible en plantas. |
| ZA885916B (en) * | 1987-09-15 | 1989-04-26 | Gen Hospital Corp | Pathogenesis-related proteins in plants |
| CN1033645A (zh) * | 1988-10-22 | 1989-07-05 | 中国科学院上海植物生理研究所 | 控制植物病毒病的基因工程方法 |
| NL9001711A (nl) * | 1989-10-03 | 1991-05-01 | Clovis Matton N V | Genetische manipulaties met recombinant dna, dat van rna virus afgeleide sequenties omvat. |
| WO1991013994A1 (en) * | 1990-03-13 | 1991-09-19 | Commonwealth Scientific And Industrial Research Organisation | Gene expression |
| EP0479180A3 (en) * | 1990-10-05 | 1992-08-26 | Hoechst Aktiengesellschaft | Virus resistant plants, method for their production |
| NZ241310A (en) * | 1991-01-17 | 1995-03-28 | Gen Hospital Corp | Trans-splicing ribozymes |
| NZ314630A (en) * | 1991-01-17 | 2000-11-24 | Harvard College | Use of trans-splicing ribozymes for genetic modification and cell ablation in a host cell |
| CA2100251A1 (en) * | 1991-01-25 | 1992-07-26 | Robert L. Lechner | Regulation of nucleic acid translation |
-
1993
- 1993-05-06 JP JP6503629A patent/JPH07507931A/ja active Pending
- 1993-05-06 CA CA 2135643 patent/CA2135643A1/en not_active Abandoned
- 1993-05-06 AU AU42342/93A patent/AU4234293A/en not_active Abandoned
- 1993-05-06 EP EP93911073A patent/EP0641384A4/en not_active Withdrawn
- 1993-05-06 WO PCT/US1993/004240 patent/WO1993023532A1/en not_active Application Discontinuation
- 1993-05-13 MX MX9302804A patent/MX9302804A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU4234293A (en) | 1993-12-13 |
| JPH07507931A (ja) | 1995-09-07 |
| EP0641384A1 (en) | 1995-03-08 |
| EP0641384A4 (en) | 1995-07-12 |
| WO1993023532A1 (en) | 1993-11-25 |
| CA2135643A1 (en) | 1993-11-25 |
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