MX9203050A - Compuestos de analogos de triptamina. - Google Patents

Compuestos de analogos de triptamina.

Info

Publication number
MX9203050A
MX9203050A MX9203050A MX9203050A MX9203050A MX 9203050 A MX9203050 A MX 9203050A MX 9203050 A MX9203050 A MX 9203050A MX 9203050 A MX9203050 A MX 9203050A MX 9203050 A MX9203050 A MX 9203050A
Authority
MX
Mexico
Prior art keywords
pct
date
triptamine
sec
analog compounds
Prior art date
Application number
MX9203050A
Other languages
English (en)
Spanish (es)
Inventor
Lawrence Ivan Kruse Rodney
Christopher Young
Alberto Julio Kaumann
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB919113382A external-priority patent/GB9113382D0/en
Priority claimed from GB919113385A external-priority patent/GB9113385D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of MX9203050A publication Critical patent/MX9203050A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
MX9203050A 1991-06-21 1992-06-19 Compuestos de analogos de triptamina. MX9203050A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919113382A GB9113382D0 (en) 1991-06-21 1991-06-21 Compounds
GB919113385A GB9113385D0 (en) 1991-06-21 1991-06-21 Compounds

Publications (1)

Publication Number Publication Date
MX9203050A true MX9203050A (es) 1993-07-01

Family

ID=26299103

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9203050A MX9203050A (es) 1991-06-21 1992-06-19 Compuestos de analogos de triptamina.

Country Status (13)

Country Link
US (1) US5571833A (member.php)
EP (1) EP0593513B1 (member.php)
JP (1) JPH06508354A (member.php)
AT (1) ATE172723T1 (member.php)
AU (1) AU1928892A (member.php)
CA (1) CA2110574A1 (member.php)
DE (1) DE69227458T2 (member.php)
DK (1) DK0593513T3 (member.php)
IE (1) IE921993A1 (member.php)
MX (1) MX9203050A (member.php)
PT (1) PT100603A (member.php)
TW (1) TW217407B (member.php)
WO (1) WO1993000333A1 (member.php)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
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GB9211277D0 (en) 1992-05-28 1992-07-15 Glaxo Group Inc Pharmaceutical compositions
GB9226532D0 (en) * 1992-12-21 1993-02-17 Smithkline Beecham Plc Compounds
FR2701026B1 (fr) * 1993-02-02 1995-03-31 Adir Nouveaux dérivés de l'indole, de l'indazole et du benzisoxazole, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
US5496957A (en) * 1993-09-01 1996-03-05 Virginia Commonwealth University Tryptamine analogs with 5-HT1D selectivity
AU685837B2 (en) * 1993-09-01 1998-01-29 Allelix Biopharmaceuticals Inc. Tryptamine analogs with 5-HT1D selectivity
US5504101A (en) * 1994-05-06 1996-04-02 Allelix Biopharmaceuticals, Inc. 5-HT-1D receptor ligands
JPH10509721A (ja) * 1994-12-06 1998-09-22 メルク シヤープ エンド ドーム リミテツド ５ｈｔ１レセプターアゴニストとしてのアゼチジン、ピロリジン及びピペリジン誘導体
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
CN1269484C (zh) 1998-09-18 2006-08-16 艾尔科实验室公司 用于治疗青光眼的5－羟色胺激活性激动剂
EP1132389A1 (en) * 2000-03-06 2001-09-12 Vernalis Research Limited New aza-indolyl derivatives for the treatment of obesity
US6806285B1 (en) 2000-03-17 2004-10-19 Alcon, Inc. 5-Hydroxyl indole derivatives for treating glaucoma
AU2001216035A1 (en) * 2000-03-17 2001-10-03 Alcon Universal Ltd. 5-hydroxy indole derivatives for treating glaucoma
US7005443B1 (en) * 2000-03-17 2006-02-28 Alcon, Inc. 5-Hydroxy indazole derivatives for treating glaucoma
US7012090B1 (en) 2000-03-17 2006-03-14 Alcon, Inc. Pyranoindoles for treating glaucoma
US6956036B1 (en) 2000-03-17 2005-10-18 Alcon, Inc. 6-hydroxy-indazole derivatives for treating glaucoma
WO2001070705A1 (en) 2000-03-17 2001-09-27 Alcon, Inc. 2-acylaminobenzimidazole derivatives for treating glaucoma
WO2004098807A1 (en) * 2000-11-21 2004-11-18 Barsplice Products, Inc. Method of making steel couplers for joining concrete reinforcing bars
WO2002079153A1 (en) * 2001-03-28 2002-10-10 Biocatalytics, Inc. Method for producing tryptamine derivatives
CN100384417C (zh) * 2001-06-01 2008-04-30 艾尔科公司 吡喃并吲唑类化合物及其用于制备治疗青光眼药物的用途
WO2002098860A1 (en) * 2001-06-01 2002-12-12 Alcon, Inc. Novel fused indazoles and indoles and their use for the treatment of glaucoma
JP2004534781A (ja) * 2001-06-01 2004-11-18 アルコン，インコーポレイテッド 新規なアリールアミノプロパン類似体および緑内障治療へのこれらの使用
US6884816B2 (en) * 2001-08-31 2005-04-26 Alcon, Inc. Hydroxy substituted fused naphthyl-azoles and fused indeno-azoles and their use for the treatment of glaucoma
AU2002364711A1 (en) * 2001-12-14 2003-06-30 Alcon, Inc. Substituted 5-hydroxy-indole compounds for the treatment of glaucoma
TW593302B (en) * 2001-12-20 2004-06-21 Alcon Inc Novel benzodifuranimidazoline and benzofuranimidazoline derivatives and their use for the treatment of glaucoma
EP1545501A2 (en) * 2002-08-30 2005-06-29 Alcon, Inc. Substituted 5-chroman-5-yl-ethylamine compounds and their use for the treatment of glaucoma
RU2227140C1 (ru) * 2002-10-22 2004-04-20 Закрытое Акционерное Общество "Лорр" Способ получения серотонина и его фармакологических солей
MXPA05006277A (es) * 2002-12-13 2005-09-08 Alcon Inc Analogos de benzopirano novedosos y su uso para el tratamiento de glaucoma.
US7645886B2 (en) 2002-12-20 2010-01-12 Ciba Specialty Corporation Synthesis of amines and intermediates for the synthesis thereof
US7476687B2 (en) * 2003-11-26 2009-01-13 Alcon, Inc. Substituted furo[2,3-g]indazoles for the treatment of glaucoma
US7338972B1 (en) 2003-12-15 2008-03-04 Alcon, Inc. Substituted 1-alkylamino-1H-indazoles for the treatment of glaucoma
US7129257B1 (en) * 2003-12-15 2006-10-31 Alcon, Inc. Pyrazolo[3,4- e]benzoxazoles for the treatment of glaucoma
TW200520760A (en) * 2003-12-15 2005-07-01 Alcon Inc Substituted [1,4] oxazino [2,3-g] indazoles for the treatment of glaucoma
US20060073172A1 (en) * 2004-10-01 2006-04-06 Schneider L W Stabilized ophthalmic solution for the treatment of glaucoma and lowering intraocular pressure
WO2006062839A1 (en) * 2004-12-08 2006-06-15 Alcon, Inc. Use of dioxindoindazoles and dioxoloindazoles for treating glaucoma
TW200744567A (en) * 2005-09-23 2007-12-16 Alcon Inc Phenylethylamine analogs and their use for treating glaucoma
US20070293475A1 (en) * 2006-06-20 2007-12-20 Alcon Manufacturing Ltd. Aryl and heteroaryl tetrahydrobenzazepine derivatives and their use for treating glaucoma
JP5868980B2 (ja) * 2010-09-14 2016-02-24 カウンシル オブ サイエンティフィック アンド インダストリアル リサーチ トリプタミン誘導体、その製造方法および胃疾患についての使用
WO2018204354A1 (en) * 2017-05-01 2018-11-08 The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Compositions and methods to reduce pathogenesis
GB201907871D0 (en) 2019-06-03 2019-07-17 Small Pharma Ltd Therapeutic compositions
ES2940811T3 (es) * 2019-11-07 2023-05-11 Small Pharma Ltd Método de síntesis
US11773062B2 (en) 2021-03-22 2023-10-03 Small Pharma Ltd Deuterated compounds
CN116472274B (zh) * 2020-09-04 2025-12-16 吉尔伽美什制药公司 氮杂环丁烷基色胺和治疗精神障碍的方法
US12521370B2 (en) 2020-12-01 2026-01-13 Cybin Uk Ltd Inhalable formulations
US11660289B2 (en) 2020-12-01 2023-05-30 Small Pharma Ltd. Deuterated or partially deuterated N,N-dimethyltryptamine compounds
EP4271682A4 (en) * 2020-12-31 2025-03-12 1280225 B.C. Ltd. Method of synthesizing indole compounds
CA3222970A1 (en) * 2021-07-26 2023-02-02 Charles Nichols Compounds and methods for treating 5-ht2 responsive conditions
US11697638B2 (en) 2021-09-08 2023-07-11 Small Pharma Ltd 5-methoxy-N,N-dimethyltryptamine crystalline forms
CN118696029A (zh) * 2021-12-24 2024-09-24 普赛洛私人有限公司 化合物
WO2024138007A2 (en) * 2022-12-21 2024-06-27 Caamtech, Inc. Tryptamine derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5883671A (ja) * 1981-11-11 1983-05-19 Mitsui Toatsu Chem Inc トリプタミン誘導体の製造法
KR920701152A (ko) * 1988-11-14 1992-08-11 로버트 에이. 아미테이지 당뇨병, 비반증 및 동맥경화증 치료제로 유용한 알파-아미노-인돌-3-세트산

Also Published As

Publication number Publication date
PT100603A (pt) 1993-08-31
EP0593513B1 (en) 1998-10-28
US5571833A (en) 1996-11-05
TW217407B (member.php) 1993-12-11
ATE172723T1 (de) 1998-11-15
CA2110574A1 (en) 1993-01-07
JPH06508354A (ja) 1994-09-22
AU1928892A (en) 1993-01-25
IE921993A1 (en) 1992-12-30
DE69227458D1 (de) 1998-12-03
DK0593513T3 (da) 1999-07-05
EP0593513A1 (en) 1994-04-27
DE69227458T2 (de) 1999-04-29
WO1993000333A1 (en) 1993-01-07

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