MX5974E - Procedimiento para preparar una xantina 1,3-delta 1,3,8-substituida - Google Patents
Procedimiento para preparar una xantina 1,3-delta 1,3,8-substituidaInfo
- Publication number
- MX5974E MX5974E MX819429U MX942981U MX5974E MX 5974 E MX5974 E MX 5974E MX 819429 U MX819429 U MX 819429U MX 942981 U MX942981 U MX 942981U MX 5974 E MX5974 E MX 5974E
- Authority
- MX
- Mexico
- Prior art keywords
- delta
- preparing
- procedure
- substituted xanthine
- xanthine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/553—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/60—Three or more oxygen or sulfur atoms
- C07D239/62—Barbituric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH343180A CH643260A5 (fr) | 1980-05-02 | 1980-05-02 | 1-allyl-3-butyl-8-methylxanthine, procede de preparation et utilisation dans un medicament. |
Publications (1)
Publication Number | Publication Date |
---|---|
MX5974E true MX5974E (es) | 1984-09-11 |
Family
ID=4255824
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX819429U MX5974E (es) | 1980-05-02 | 1981-04-30 | Procedimiento para preparar una xantina 1,3-delta 1,3,8-substituida |
Country Status (21)
Country | Link |
---|---|
US (2) | US4469698A (es) |
EP (1) | EP0039780B1 (es) |
JP (1) | JPS56169690A (es) |
AU (1) | AU539258B2 (es) |
CA (1) | CA1155841A (es) |
CH (1) | CH643260A5 (es) |
CS (1) | CS221829B2 (es) |
DD (1) | DD158776A5 (es) |
DE (1) | DE3169784D1 (es) |
DK (1) | DK149856C (es) |
ES (1) | ES8207532A1 (es) |
FI (1) | FI68831C (es) |
GB (1) | GB2075505B (es) |
HK (1) | HK49985A (es) |
HU (1) | HU185256B (es) |
IL (1) | IL62641A (es) |
MX (1) | MX5974E (es) |
MY (1) | MY8500517A (es) |
PH (2) | PH17137A (es) |
PL (1) | PL135383B1 (es) |
SG (1) | SG20884G (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4772607A (en) * | 1986-05-20 | 1988-09-20 | Warner-Lambert Company | Dialkenyl derivatives of xanthine, pharmaceutical compositions and methods of use therefor |
US4755517A (en) * | 1986-07-31 | 1988-07-05 | Warner-Lambert Company | Derivatives of xanthine, pharmaceutical compositions and methods of use therefor |
US5338741A (en) * | 1986-10-27 | 1994-08-16 | Nestec S.A. | 1-hydroxyalkylxanthines and medicaments containing them |
US5298508A (en) * | 1988-07-19 | 1994-03-29 | The United States Of America As Represented By The Department Of Health And Human Services | Irreversible inhibitors of adenosine receptors |
GB8826595D0 (en) * | 1988-11-14 | 1988-12-21 | Beecham Wuelfing Gmbh & Co Kg | Active compounds |
EP0407651A3 (en) * | 1989-07-10 | 1991-08-07 | J. Uriach & Cia. S.A. | Use of 1,3-diisobutyl-8-methylxanthine as a bronchodilator and antiallergy agent |
AU681875B2 (en) * | 1993-02-26 | 1997-09-11 | Schering Corporation | 2-benzyl-polycyclic guanine derivatives and process for preparing them |
GB9312853D0 (en) * | 1993-06-22 | 1993-08-04 | Euro Celtique Sa | Chemical compounds |
US5591776A (en) * | 1994-06-24 | 1997-01-07 | Euro-Celtique, S.A. | Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV |
US5922751A (en) * | 1994-06-24 | 1999-07-13 | Euro-Celtique, S.A. | Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same |
DE69531555T2 (de) * | 1994-12-13 | 2004-06-17 | Euroceltique S.A. | Dreifachsubstituierte thioxanthine |
CA2206287C (en) * | 1994-12-13 | 2001-03-20 | Mark Chasin | Aryl thioxanthines |
US6166041A (en) * | 1995-10-11 | 2000-12-26 | Euro-Celtique, S.A. | 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma |
FR2741455B1 (fr) * | 1995-11-21 | 1997-12-26 | Alcatel Optronics | Procede de formation d'une nappe de fibres optiques inclinees a dioptres de couplage |
US6075016A (en) * | 1996-04-10 | 2000-06-13 | Euro-Celtique S.A. | 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity |
US5864037A (en) | 1996-06-06 | 1999-01-26 | Euro-Celtique, S.A. | Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity |
DE10018834A1 (de) * | 2000-04-15 | 2001-10-25 | Lohmann Therapie Syst Lts | Transdermale oder transmucosale Darreichungsformen mit einer nicotinhaltigen Wirkstoffkombination zur Raucherentwöhnung |
US9221821B2 (en) * | 2012-06-05 | 2015-12-29 | Forest Laboratories Holdings, Limited | Methods for the synthesis of 1,3-substituted aminouracils and other xanthine-related compounds |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB701242A (en) * | 1950-11-28 | 1953-12-23 | Searle & Co | Improvements in or relating to disubstituted 6-amino-1,2,3,4-tetrahydro-2,4-pyrimidinediones and methods of preparing the same |
US2673848A (en) * | 1951-12-29 | 1954-03-30 | Searle & Co | 3-alkenylxanthines and their lower 1-alkyl derivatives |
GB759174A (en) * | 1952-11-07 | 1956-10-17 | Geigy Ag J R | Improvements in diuretic acting xanthine derivatives |
GB766754A (en) * | 1954-01-27 | 1957-01-23 | Geigy Ag J R | New derivatives of 1.3-disubstituted and 1.3.8-trisubstituted xanthines and processes for their production |
DE1091570B (de) * | 1958-10-23 | 1960-10-27 | Albert Ag Chem Werke | Verfahren zur Herstellung von in 8-Stellung substituierten 1, 3-Dialkylxanthinen |
GB982079A (en) * | 1962-05-01 | 1965-02-03 | Dresden Arzneimittel | Process for the production of xanthine derivatives |
US3740433A (en) * | 1971-10-01 | 1973-06-19 | Squibb & Sons Inc | Anti-anxiety composition and method of use |
CA1077932A (en) * | 1976-03-31 | 1980-05-20 | Berlex Laboratories, Inc. | Xanthine compounds and method of treating bronchospastic and allergic diseases |
US4089959A (en) * | 1976-03-31 | 1978-05-16 | Cooper Laboratories, Inc. | Long-acting xanthine bronchodilators and antiallergy agents |
SE7810947L (sv) * | 1978-10-20 | 1980-04-21 | Draco Ab | 3-alkylxanthines |
CH654008A5 (fr) * | 1979-05-22 | 1986-01-31 | Nestle Sa | Procede de preparation de 1,3,7-trialkylxanthines. |
-
1980
- 1980-05-02 CH CH343180A patent/CH643260A5/fr not_active IP Right Cessation
-
1981
- 1981-04-06 DE DE8181102573T patent/DE3169784D1/de not_active Expired
- 1981-04-06 EP EP81102573A patent/EP0039780B1/fr not_active Expired
- 1981-04-07 FI FI811067A patent/FI68831C/fi not_active IP Right Cessation
- 1981-04-08 DK DK158481A patent/DK149856C/da not_active IP Right Cessation
- 1981-04-14 IL IL62641A patent/IL62641A/xx not_active IP Right Cessation
- 1981-04-15 CA CA000375586A patent/CA1155841A/en not_active Expired
- 1981-04-16 AU AU69617/81A patent/AU539258B2/en not_active Ceased
- 1981-04-27 PH PH25561A patent/PH17137A/en unknown
- 1981-04-28 DD DD81229559A patent/DD158776A5/de not_active IP Right Cessation
- 1981-04-30 CS CS813240A patent/CS221829B2/cs unknown
- 1981-04-30 MX MX819429U patent/MX5974E/es unknown
- 1981-04-30 PL PL1981230936A patent/PL135383B1/pl unknown
- 1981-04-30 HU HU811143A patent/HU185256B/hu not_active IP Right Cessation
- 1981-04-30 GB GB8113418A patent/GB2075505B/en not_active Expired
- 1981-04-30 ES ES502414A patent/ES8207532A1/es not_active Expired
- 1981-05-01 JP JP6676681A patent/JPS56169690A/ja active Pending
-
1982
- 1982-05-25 PH PH27345A patent/PH17660A/en unknown
-
1983
- 1983-02-28 US US06/470,301 patent/US4469698A/en not_active Expired - Fee Related
-
1984
- 1984-03-06 SG SG208/84A patent/SG20884G/en unknown
- 1984-06-08 US US06/618,909 patent/US4581451A/en not_active Expired - Fee Related
-
1985
- 1985-06-27 HK HK499/85A patent/HK49985A/xx unknown
- 1985-12-30 MY MY517/85A patent/MY8500517A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
CH643260A5 (fr) | 1984-05-30 |
US4581451A (en) | 1986-04-08 |
PL135383B1 (en) | 1985-10-31 |
GB2075505A (en) | 1981-11-18 |
ES502414A0 (es) | 1982-10-01 |
DK158481A (da) | 1981-11-03 |
US4469698A (en) | 1984-09-04 |
IL62641A0 (en) | 1981-06-29 |
FI68831B (fi) | 1985-07-31 |
DK149856C (da) | 1987-05-25 |
DD158776A5 (de) | 1983-02-02 |
DK149856B (da) | 1986-10-13 |
JPS56169690A (en) | 1981-12-26 |
PH17660A (en) | 1984-10-25 |
MY8500517A (en) | 1985-12-31 |
SG20884G (en) | 1985-01-04 |
AU6961781A (en) | 1981-11-05 |
GB2075505B (en) | 1984-01-11 |
IL62641A (en) | 1985-01-31 |
FI811067L (fi) | 1981-11-03 |
DE3169784D1 (en) | 1985-05-15 |
AU539258B2 (en) | 1984-09-20 |
CA1155841A (en) | 1983-10-25 |
ES8207532A1 (es) | 1982-10-01 |
PL230936A1 (es) | 1982-06-07 |
EP0039780A1 (fr) | 1981-11-18 |
FI68831C (fi) | 1985-11-11 |
HU185256B (en) | 1984-12-28 |
CS221829B2 (en) | 1983-04-29 |
PH17137A (en) | 1984-06-04 |
EP0039780B1 (fr) | 1985-04-10 |
HK49985A (en) | 1985-07-05 |
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