MX5974E - Procedimiento para preparar una xantina 1,3-delta 1,3,8-substituida - Google Patents

Procedimiento para preparar una xantina 1,3-delta 1,3,8-substituida

Info

Publication number
MX5974E
MX5974E MX819429U MX942981U MX5974E MX 5974 E MX5974 E MX 5974E MX 819429 U MX819429 U MX 819429U MX 942981 U MX942981 U MX 942981U MX 5974 E MX5974 E MX 5974E
Authority
MX
Mexico
Prior art keywords
delta
preparing
procedure
substituted xanthine
xanthine
Prior art date
Application number
MX819429U
Other languages
English (en)
Inventor
Georges Philippossian
Marc Enslen
Original Assignee
Nestle Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nestle Sa filed Critical Nestle Sa
Publication of MX5974E publication Critical patent/MX5974E/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • C07D239/54Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/553Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • C07D239/54Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60Three or more oxygen or sulfur atoms
    • C07D239/62Barbituric acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MX819429U 1980-05-02 1981-04-30 Procedimiento para preparar una xantina 1,3-delta 1,3,8-substituida MX5974E (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH343180A CH643260A5 (fr) 1980-05-02 1980-05-02 1-allyl-3-butyl-8-methylxanthine, procede de preparation et utilisation dans un medicament.

Publications (1)

Publication Number Publication Date
MX5974E true MX5974E (es) 1984-09-11

Family

ID=4255824

Family Applications (1)

Application Number Title Priority Date Filing Date
MX819429U MX5974E (es) 1980-05-02 1981-04-30 Procedimiento para preparar una xantina 1,3-delta 1,3,8-substituida

Country Status (21)

Country Link
US (2) US4469698A (es)
EP (1) EP0039780B1 (es)
JP (1) JPS56169690A (es)
AU (1) AU539258B2 (es)
CA (1) CA1155841A (es)
CH (1) CH643260A5 (es)
CS (1) CS221829B2 (es)
DD (1) DD158776A5 (es)
DE (1) DE3169784D1 (es)
DK (1) DK149856C (es)
ES (1) ES8207532A1 (es)
FI (1) FI68831C (es)
GB (1) GB2075505B (es)
HK (1) HK49985A (es)
HU (1) HU185256B (es)
IL (1) IL62641A (es)
MX (1) MX5974E (es)
MY (1) MY8500517A (es)
PH (2) PH17137A (es)
PL (1) PL135383B1 (es)
SG (1) SG20884G (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4772607A (en) * 1986-05-20 1988-09-20 Warner-Lambert Company Dialkenyl derivatives of xanthine, pharmaceutical compositions and methods of use therefor
US4755517A (en) * 1986-07-31 1988-07-05 Warner-Lambert Company Derivatives of xanthine, pharmaceutical compositions and methods of use therefor
US5338741A (en) * 1986-10-27 1994-08-16 Nestec S.A. 1-hydroxyalkylxanthines and medicaments containing them
US5298508A (en) * 1988-07-19 1994-03-29 The United States Of America As Represented By The Department Of Health And Human Services Irreversible inhibitors of adenosine receptors
GB8826595D0 (en) * 1988-11-14 1988-12-21 Beecham Wuelfing Gmbh & Co Kg Active compounds
EP0407651A3 (en) * 1989-07-10 1991-08-07 J. Uriach & Cia. S.A. Use of 1,3-diisobutyl-8-methylxanthine as a bronchodilator and antiallergy agent
AU681875B2 (en) * 1993-02-26 1997-09-11 Schering Corporation 2-benzyl-polycyclic guanine derivatives and process for preparing them
GB9312853D0 (en) * 1993-06-22 1993-08-04 Euro Celtique Sa Chemical compounds
US5591776A (en) * 1994-06-24 1997-01-07 Euro-Celtique, S.A. Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV
US5922751A (en) * 1994-06-24 1999-07-13 Euro-Celtique, S.A. Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same
DE69531555T2 (de) * 1994-12-13 2004-06-17 Euroceltique S.A. Dreifachsubstituierte thioxanthine
CA2206287C (en) * 1994-12-13 2001-03-20 Mark Chasin Aryl thioxanthines
US6166041A (en) * 1995-10-11 2000-12-26 Euro-Celtique, S.A. 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma
FR2741455B1 (fr) * 1995-11-21 1997-12-26 Alcatel Optronics Procede de formation d'une nappe de fibres optiques inclinees a dioptres de couplage
US6075016A (en) * 1996-04-10 2000-06-13 Euro-Celtique S.A. 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity
US5864037A (en) 1996-06-06 1999-01-26 Euro-Celtique, S.A. Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity
DE10018834A1 (de) * 2000-04-15 2001-10-25 Lohmann Therapie Syst Lts Transdermale oder transmucosale Darreichungsformen mit einer nicotinhaltigen Wirkstoffkombination zur Raucherentwöhnung
US9221821B2 (en) * 2012-06-05 2015-12-29 Forest Laboratories Holdings, Limited Methods for the synthesis of 1,3-substituted aminouracils and other xanthine-related compounds

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB701242A (en) * 1950-11-28 1953-12-23 Searle & Co Improvements in or relating to disubstituted 6-amino-1,2,3,4-tetrahydro-2,4-pyrimidinediones and methods of preparing the same
US2673848A (en) * 1951-12-29 1954-03-30 Searle & Co 3-alkenylxanthines and their lower 1-alkyl derivatives
GB759174A (en) * 1952-11-07 1956-10-17 Geigy Ag J R Improvements in diuretic acting xanthine derivatives
GB766754A (en) * 1954-01-27 1957-01-23 Geigy Ag J R New derivatives of 1.3-disubstituted and 1.3.8-trisubstituted xanthines and processes for their production
DE1091570B (de) * 1958-10-23 1960-10-27 Albert Ag Chem Werke Verfahren zur Herstellung von in 8-Stellung substituierten 1, 3-Dialkylxanthinen
GB982079A (en) * 1962-05-01 1965-02-03 Dresden Arzneimittel Process for the production of xanthine derivatives
US3740433A (en) * 1971-10-01 1973-06-19 Squibb & Sons Inc Anti-anxiety composition and method of use
CA1077932A (en) * 1976-03-31 1980-05-20 Berlex Laboratories, Inc. Xanthine compounds and method of treating bronchospastic and allergic diseases
US4089959A (en) * 1976-03-31 1978-05-16 Cooper Laboratories, Inc. Long-acting xanthine bronchodilators and antiallergy agents
SE7810947L (sv) * 1978-10-20 1980-04-21 Draco Ab 3-alkylxanthines
CH654008A5 (fr) * 1979-05-22 1986-01-31 Nestle Sa Procede de preparation de 1,3,7-trialkylxanthines.

Also Published As

Publication number Publication date
CH643260A5 (fr) 1984-05-30
US4581451A (en) 1986-04-08
PL135383B1 (en) 1985-10-31
GB2075505A (en) 1981-11-18
ES502414A0 (es) 1982-10-01
DK158481A (da) 1981-11-03
US4469698A (en) 1984-09-04
IL62641A0 (en) 1981-06-29
FI68831B (fi) 1985-07-31
DK149856C (da) 1987-05-25
DD158776A5 (de) 1983-02-02
DK149856B (da) 1986-10-13
JPS56169690A (en) 1981-12-26
PH17660A (en) 1984-10-25
MY8500517A (en) 1985-12-31
SG20884G (en) 1985-01-04
AU6961781A (en) 1981-11-05
GB2075505B (en) 1984-01-11
IL62641A (en) 1985-01-31
FI811067L (fi) 1981-11-03
DE3169784D1 (en) 1985-05-15
AU539258B2 (en) 1984-09-20
CA1155841A (en) 1983-10-25
ES8207532A1 (es) 1982-10-01
PL230936A1 (es) 1982-06-07
EP0039780A1 (fr) 1981-11-18
FI68831C (fi) 1985-11-11
HU185256B (en) 1984-12-28
CS221829B2 (en) 1983-04-29
PH17137A (en) 1984-06-04
EP0039780B1 (fr) 1985-04-10
HK49985A (en) 1985-07-05

Similar Documents

Publication Publication Date Title
ES543732A0 (es) Un procedimiento para preparar derivados de aminoalquilfenaxi.
ES500726A0 (es) Un procedimiento para preparar diaminopiridinas
ES553610A0 (es) Un procedimiento para preparar derivados de alanil-protina.
MX5974E (es) Procedimiento para preparar una xantina 1,3-delta 1,3,8-substituida
ES538518A0 (es) Un procedimiento para preparar derivados de 3-aminopirazolo-(3,4-d)-pirimidina
ES530024A0 (es) Un procedimiento para preparar derivados de pirazinona
ES538238A0 (es) Un procedimiento para preparar derivados de adenosina.
ES500727A0 (es) Un procedimiento para preparar imidazo-piridinas
ES528304A0 (es) Un procedimiento para preparar derivados de pirimidona
ES528003A0 (es) Un procedimiento para preparar derivados de cefem
AR231308A1 (es) Un procedimiento para preparar 1-be-d-ribofuranosil-1,2,4-triazolcarboxamida rivavirina
ES530392A0 (es) Un metodo para preparar derivados de 4-hidroxi-2-quinolona.
ES518758A0 (es) Un procedimiento para preparar azetidinas.
ES555009A0 (es) Un procedimiento para preparar derivados de 3-hidroxibutanamido-acetato.
ES505656A0 (es) Un procedimiento para preparar nuevos derivados de antraci- clina
ES527304A0 (es) Un procedimiento para preparar derivados de pirimidona.
ES500412A0 (es) Un procedimiento para preparar una pirazolopiridina
ES519936A0 (es) Un procedimiento para preparar derivados de pirimidona.
ES538036A0 (es) Un procedimiento para preparar derivados de piridona.
ES522716A0 (es) Un procedimiento para preparar un derivado de pirazol.
ES524772A0 (es) Un procedimiento para preparar fenilanilinas-n.sustituidas.
ES526177A0 (es) Un procedimiento para preparar derivados de pirimidona
ES506930A0 (es) Un procedimiento para preparar derivados de n-fenil-dicloro-maleimida.
ES506302A0 (es) Un procedimiento para preparar derivados de tetrahidroiso- quinoleinas
ES538032A0 (es) Un procedimiento para preparar derivados de isoxazolamina.