MX394142B - Método para la separación de proteína y otras impurezas de polisacáridos capsulares microbianos. - Google Patents

Método para la separación de proteína y otras impurezas de polisacáridos capsulares microbianos.

Info

Publication number
MX394142B
MX394142B MX2017013855A MX2017013855A MX394142B MX 394142 B MX394142 B MX 394142B MX 2017013855 A MX2017013855 A MX 2017013855A MX 2017013855 A MX2017013855 A MX 2017013855A MX 394142 B MX394142 B MX 394142B
Authority
MX
Mexico
Prior art keywords
impurities
capsular polysaccharides
protein
separation
microbial capsular
Prior art date
Application number
MX2017013855A
Other languages
English (en)
Other versions
MX2017013855A (es
Inventor
Kantam Charan
Mahima Datla
Muthyala Venkateswara Reddy
Narender Dev Mantena
Ramesh Venkat Matur
Vivek Babu Kandimalla
Original Assignee
Biological E Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biological E Ltd filed Critical Biological E Ltd
Publication of MX2017013855A publication Critical patent/MX2017013855A/es
Publication of MX394142B publication Critical patent/MX394142B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0003—General processes for their isolation or fractionation, e.g. purification or extraction from biomass
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6068—Other bacterial proteins, e.g. OMP
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Sustainable Development (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Materials Engineering (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención se refiere a un método para la eliminación de proteínas y otras impurezas de polisacáridos capsulares microbianos. Más particularmente, la presente invención se refiere al aislamiento de polisacáridos capsulares microbianos en forma pura después de la eliminación de proteínas y otras impurezas.
MX2017013855A 2015-04-28 2016-04-25 Método para la separación de proteína y otras impurezas de polisacáridos capsulares microbianos. MX394142B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2161CH2015 2015-04-28
PCT/IN2016/000107 WO2016174683A1 (en) 2015-04-28 2016-04-25 Method for separation of protein and other impurities from microbial capsular polysaccharides

Publications (2)

Publication Number Publication Date
MX2017013855A MX2017013855A (es) 2018-03-15
MX394142B true MX394142B (es) 2025-03-24

Family

ID=56137482

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017013855A MX394142B (es) 2015-04-28 2016-04-25 Método para la separación de proteína y otras impurezas de polisacáridos capsulares microbianos.

Country Status (12)

Country Link
US (2) US10836839B2 (es)
EP (1) EP3288983B1 (es)
JP (1) JP6882193B2 (es)
CN (1) CN107835821B (es)
AU (1) AU2016254693B2 (es)
BR (1) BR112017023437B1 (es)
CA (1) CA2983708C (es)
EA (1) EA201792366A1 (es)
MX (1) MX394142B (es)
SA (1) SA517390202B1 (es)
WO (1) WO2016174683A1 (es)
ZA (1) ZA201707454B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2017321863B2 (en) 2016-09-02 2024-07-11 Sanofi Pasteur, Inc. Neisseria meningitidis vaccine
IL265623B2 (en) 2016-09-30 2023-04-01 Biological E Ltd Multivalent vaccines for lung spot that include polysaccharide-protein conjugates
US20210108002A1 (en) * 2016-12-06 2021-04-15 Glaxosmithkline Biologicals Sa Purification Process For Capsular Polysaccharide
US10729763B2 (en) 2017-06-10 2020-08-04 Inventprise, Llc Mixtures of polysaccharide-protein pegylated compounds
CN113194987B (zh) 2018-10-12 2024-11-08 生物E有限公司 多价肺炎球菌多糖-蛋白缀合的疫苗
US12276645B2 (en) 2019-10-01 2025-04-15 Biological E Limited Methods for quantification of carbohydrates
JP2023504785A (ja) * 2019-11-29 2023-02-07 ロンザ リミテッド 多糖を精製する方法
CN116693706B (zh) * 2022-02-24 2024-10-11 成都生物制品研究所有限责任公司 一种肺炎链球菌荚膜多糖的纯化方法
CN117512031B (zh) * 2023-10-16 2024-06-25 江苏金迪克生物技术股份有限公司 一种肺炎球菌荚膜多糖的纯化方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4242501A (en) 1979-08-08 1980-12-30 American Cyanamid Company Purification of pneumococcal capsular polysaccharides
CA2059693C (en) 1991-01-28 2003-08-19 Peter J. Kniskern Polysaccharide antigens from streptococcus pneumoniae
US5714354A (en) 1995-06-06 1998-02-03 American Home Products Corporation Alcohol-free pneumococcal polysaccharide purification process
WO1999039739A1 (en) * 1998-02-05 1999-08-12 Henry M. Jackson Foundation For The Advancement Of Military Medicine Simplified method for removing free protein during preparation of protein-polysaccharide conjugates and vaccines using restricted-access media
GB0502096D0 (en) 2005-02-01 2005-03-09 Chiron Srl Purification of streptococcal capsular polysaccharide
WO2008035372A2 (en) 2006-07-06 2008-03-27 Reliance Life Sciences Pvt Ltd Efficient process for purification of high molecular weight hyaluronic acid
RU2460539C2 (ru) 2006-10-10 2012-09-10 Вайет СПОСОБ ОЧИСТКИ ПОЛИСАХАРИДОВ Streptococcus pneumoniae 3 ТИПА (ВАРИАНТЫ)
PL3170508T3 (pl) * 2010-06-04 2020-04-30 Wyeth Llc Preparaty szczepionek
BR112013024322B1 (pt) 2011-03-22 2020-04-22 Serum Inst India Ltd processo para preparação de polissacarídeos
CN103623401A (zh) 2012-08-23 2014-03-12 北京科兴中维生物技术有限公司 多价肺炎球菌荚膜多糖-蛋白质共轭组合物及其制备方法
CA2937186C (en) * 2014-01-21 2022-11-01 Pfizer Inc. Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof

Also Published As

Publication number Publication date
CN107835821A (zh) 2018-03-23
US20210017300A1 (en) 2021-01-21
EP3288983A1 (en) 2018-03-07
BR112017023437A2 (pt) 2018-07-31
EA201792366A1 (ru) 2018-03-30
US10836839B2 (en) 2020-11-17
CA2983708C (en) 2023-09-19
EP3288983C0 (en) 2025-10-29
EP3288983B1 (en) 2025-10-29
CN107835821B (zh) 2022-01-28
CA2983708A1 (en) 2016-11-03
AU2016254693B2 (en) 2020-07-09
BR112017023437B1 (pt) 2022-03-22
MX2017013855A (es) 2018-03-15
US20180155453A1 (en) 2018-06-07
US11680111B2 (en) 2023-06-20
ZA201707454B (en) 2019-11-27
JP2018514624A (ja) 2018-06-07
AU2016254693A1 (en) 2017-11-09
WO2016174683A1 (en) 2016-11-03
JP6882193B2 (ja) 2021-06-02
SA517390202B1 (ar) 2021-04-19

Similar Documents

Publication Publication Date Title
MX394142B (es) Método para la separación de proteína y otras impurezas de polisacáridos capsulares microbianos.
IL280743B (en) Methods for enriching or producing immune cell populations for adoptive therapy
MY178852A (en) Process for separating a synthetic turf product
EP3201336A4 (en) Methods for extracting and purifying non-denatured proteins
MX349601B (es) Remocion de virus contaminantes de preparaciones de aav.
MX385409B (es) Proceso para manipular el nivel de contenido de glicano de una glicoproteína.
PH12016502586B1 (en) Lipid comprising docosapentaenoic acid
EP3291806A4 (en) Process to extract and purify delta-9-tetrahydrocannabinol
HUE058798T2 (hu) Eljárás borsóproteinek extrahálására
MY180732A (en) Protein manufacture
ZA201908038B (en) Method for removal of impurities from bacterial capsular polysaccharide based preparations
MX2017011979A (es) Aleaciones magneticas de cobre.
MX2017008908A (es) Proceso para la hidrólisis de queratina empleando proteasas.
PT3390517T (pt) Processo para a separação de borracha natural não hevea na forma sólida de soluções que a incluem
EA201790250A1 (ru) Способ выделения полиовируса из культур клеток
MX2017008510A (es) Emulsion y proceso para elaborarla.
PL3240887T3 (pl) Odmiana drożdży olejogennych, sposób jej otrzymywania i jej zastosowanie do wytwarzania lipidów
PH12018502207A1 (en) Methods of manufacturing nutritional formulations
SG10201909391QA (en) Lipid comprising docosapentaenoic acid
PL3134535T3 (pl) Sposób otrzymywania lipidów z biomasy z wykorzystaniem drobnoustrojów olejogennych
MX388200B (es) Compuestos de ácido nucleico para unirse al factor de diferenciación de crecimiento 11.
MX2017003612A (es) Fraccionador para separar caucho solubilizado a partir de una micela a base de cosolvente y procesos relacionados.
EP3495480A4 (en) METHOD FOR PRODUCING PEPTIDE FRAGMENTS, METHOD FOR PRODUCING PROTEASE FOR USE therein, AND KIT FOR PRODUCING PEPTIDE FRAGMENTS
MX374928B (es) Metodo para obtener l-alanina cristalina.
HK1240975A1 (en) Methods for extracting and purifying non-denatured proteins