MX394103B - Anticuerpos anti-angptl8 y usos de estos. - Google Patents
Anticuerpos anti-angptl8 y usos de estos.Info
- Publication number
- MX394103B MX394103B MX2018001532A MX2018001532A MX394103B MX 394103 B MX394103 B MX 394103B MX 2018001532 A MX2018001532 A MX 2018001532A MX 2018001532 A MX2018001532 A MX 2018001532A MX 394103 B MX394103 B MX 394103B
- Authority
- MX
- Mexico
- Prior art keywords
- antibodies
- angptl8
- bind
- angptl8 antibodies
- certain embodiments
- Prior art date
Links
- 101000924544 Homo sapiens Angiopoietin-like protein 8 Proteins 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 102100034604 Angiopoietin-like protein 8 Human genes 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 102000050918 human ANGPTL8 Human genes 0.000 abstract 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39575—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from other living beings excluding bacteria and viruses, e.g. protozoa, fungi, plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Mycology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Botany (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562202366P | 2015-08-07 | 2015-08-07 | |
| PCT/US2016/045535 WO2017027316A1 (en) | 2015-08-07 | 2016-08-04 | Anti-angptl8 antibodies and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2018001532A MX2018001532A (es) | 2018-03-15 |
| MX394103B true MX394103B (es) | 2025-03-24 |
Family
ID=56979626
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018001532A MX394103B (es) | 2015-08-07 | 2016-08-04 | Anticuerpos anti-angptl8 y usos de estos. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US10259870B2 (enExample) |
| EP (1) | EP3331908B1 (enExample) |
| JP (2) | JP7141333B2 (enExample) |
| KR (1) | KR20180038020A (enExample) |
| CN (1) | CN107922478A (enExample) |
| AR (1) | AR105600A1 (enExample) |
| AU (1) | AU2016307430B2 (enExample) |
| CA (1) | CA2993976A1 (enExample) |
| EA (1) | EA035088B1 (enExample) |
| ES (1) | ES2870031T3 (enExample) |
| HK (1) | HK1250238A1 (enExample) |
| IL (1) | IL257263A (enExample) |
| MX (1) | MX394103B (enExample) |
| TW (1) | TW201713690A (enExample) |
| WO (1) | WO2017027316A1 (enExample) |
| ZA (1) | ZA201800352B (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR087329A1 (es) | 2011-06-17 | 2014-03-19 | Regeneron Pharma | Anticuerpos humanos contra proteina 3 de tipo angiopoietina humana |
| EP3201225B1 (en) * | 2014-10-03 | 2020-08-19 | NGM Biopharmaceuticals, Inc. | Angptl8 polypeptide and its use for treatment of conditions associated with elevated triglycerides |
| TW201713690A (zh) | 2015-08-07 | 2017-04-16 | 再生元醫藥公司 | 抗ａｎｇｐｔｌ８抗體及其用途 |
| WO2017142832A1 (en) * | 2016-02-17 | 2017-08-24 | Regeneron Pharmaceuticals, Inc. | Methods for treating or preventing atherosclerosis by administering an inhibitor of angptl3 |
| CA3016764A1 (en) | 2016-03-03 | 2017-09-08 | Regeneron Pharmaceuticals, Inc. | Methods for treating patients with hyperlipidemia by administering a pcsk9 inhibitor in combination with an angptl3 inhibitor |
| US11542332B2 (en) | 2016-03-26 | 2023-01-03 | Bioatla, Inc. | Anti-CTLA4 antibodies, antibody fragments, their immunoconjugates and uses thereof |
| MX386832B (es) * | 2016-04-08 | 2025-03-19 | Regeneron Pharma | Inhibidor angptl8 e inhibidor angptl3 para usarse en el tratamiento de hiperlipidemia. |
| MA45602A (fr) | 2016-07-08 | 2019-05-15 | Staten Biotechnology B V | Anticorps anti-apoc3 et leurs méthodes d'utilisation |
| CN110036029A (zh) * | 2016-11-17 | 2019-07-19 | 瑞泽恩制药公司 | 用抗angptl8抗体处理肥胖的方法 |
| JP6853716B2 (ja) * | 2017-03-31 | 2021-03-31 | 信越化学工業株式会社 | レジスト下層膜材料、パターン形成方法、及びレジスト下層膜形成方法 |
| JP2020517242A (ja) | 2017-04-21 | 2020-06-18 | スターテン・バイオテクノロジー・ベー・フェー | 抗ＡｐｏＣ３抗体およびその使用方法 |
| US11434303B2 (en) | 2017-06-28 | 2022-09-06 | Bluefin Biomedicine, Inc. | Anti-LY6H antibodies and antibody drug conjugates |
| US10538583B2 (en) | 2017-10-31 | 2020-01-21 | Staten Biotechnology B.V. | Anti-APOC3 antibodies and compositions thereof |
| MA50516A (fr) | 2017-10-31 | 2020-09-09 | Staten Biotechnology B V | Anticorps anti-apoc3 et leurs procédés d'utilisation |
| US10774139B2 (en) | 2017-11-10 | 2020-09-15 | Ngm Biopharmaceuticals, Inc. | ANGPTL8-binding agents and methods of use thereof |
| WO2019126194A1 (en) * | 2017-12-18 | 2019-06-27 | Regeneron Pharmaceuticals, Inc. | Angptl8 assay and uses thereof |
| WO2019173438A1 (en) * | 2018-03-06 | 2019-09-12 | Stc. Unm | Compositions and methods for reducing serum triglycerides |
| TWI747098B (zh) | 2018-12-21 | 2021-11-21 | 美商美國禮來大藥廠 | 抗angptl3/8複合物抗體及其使用方法 |
| EP3930753A4 (en) | 2019-02-26 | 2023-03-29 | Twist Bioscience Corporation | VARIANT NUCLEIC ACID LIBRARIES FOR GLP1 RECEPTOR |
| EP4004051A4 (en) | 2019-07-19 | 2023-08-23 | Oncoresponse, Inc. | IMMUNOMODULATORY ANTIBODIES AND METHODS OF USE THEREOF |
| CN110613847B (zh) * | 2019-10-23 | 2022-02-11 | 北京市心肺血管疾病研究所 | 一种抑制血管生成素样蛋白8的物质的应用 |
| CN110694068A (zh) * | 2019-11-06 | 2020-01-17 | 北京市心肺血管疾病研究所 | 一种抑制血管生成素样蛋白8的物质的应用 |
| CN110694067A (zh) * | 2019-11-06 | 2020-01-17 | 首都医科大学附属北京安贞医院 | 一种抑制血管生成素样蛋白8的物质的应用 |
| CN111135303A (zh) * | 2020-01-17 | 2020-05-12 | 北京市心肺血管疾病研究所 | 一种抑制血管生成素样蛋白8的物质的应用 |
| KR20210095781A (ko) | 2020-01-24 | 2021-08-03 | 주식회사 에이프릴바이오 | 항원결합 단편 및 생리활성 이펙터 모이어티로 구성된 융합 컨스트럭트를 포함하는 다중결합항체 및 이를 포함하는 약학조성물 |
| KR20230074151A (ko) * | 2020-08-26 | 2023-05-26 | 트위스트 바이오사이언스 코포레이션 | Glp1r 변이체에 관한 방법 및 조성물 |
| CA3248667A1 (en) * | 2022-05-02 | 2023-11-09 | Novo Nordisk A/S | NEW ANTI-ANGIOPOETIN 3 TYPE ANTIBODIES SUITABLE FOR HIGH-CONCENTRATION COMPOSITIONS AND SUBCUTANEOUS ADMINISTRATION |
| WO2024069614A1 (en) * | 2022-09-30 | 2024-04-04 | 9163-0384 Québec Inc | Methods for the assessment of lipoprotein lipase deficiency and lipoprotein lipase bioavailability |
| CN119192369A (zh) * | 2023-06-25 | 2024-12-27 | 百奥泰生物制药股份有限公司 | 抗angptl3抗体及其应用 |
| CN119684452A (zh) * | 2024-12-25 | 2025-03-25 | 中国药科大学 | Angptl8中和性抗体在制备治疗细胞因子风暴综合征药物中的应用 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7368531B2 (en) | 1997-03-07 | 2008-05-06 | Human Genome Sciences, Inc. | Human secreted proteins |
| US20020132252A1 (en) | 1997-06-16 | 2002-09-19 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US7393663B2 (en) | 1997-08-01 | 2008-07-01 | Serono Genetics Institute S.A. | Expressed sequence tags and encoded human proteins |
| AU2577799A (en) | 1998-02-09 | 1999-08-23 | Human Genome Sciences, Inc. | 45 human secreted proteins |
| NZ523206A (en) | 1999-08-31 | 2004-12-24 | Genentech Inc | Antibodies that bind to tumor gene sequences |
| US6596541B2 (en) | 2000-10-31 | 2003-07-22 | Regeneron Pharmaceuticals, Inc. | Methods of modifying eukaryotic cells |
| US7598227B2 (en) | 2003-04-16 | 2009-10-06 | Isis Pharmaceuticals Inc. | Modulation of apolipoprotein C-III expression |
| JP5848861B2 (ja) | 2004-04-20 | 2016-01-27 | ジェンマブ エー／エスＧｅｎｍａｂ Ａ／Ｓ | Ｃｄ２０に対するヒトモノクローナル抗体 |
| US7537903B2 (en) | 2007-04-23 | 2009-05-26 | Board Of Regents, The University Of Texas System | FGF21 upregulates expression of GLUT-1 in a βklotho-dependent manner |
| JP2010529954A (ja) | 2007-05-22 | 2010-09-02 | ノバルティス アーゲー | Ｆｇｆ２１関連障害を処置、診断および検出する方法 |
| EP2679234A3 (en) | 2009-12-02 | 2014-04-23 | Amgen Inc. | Binding proteins that bind to human FGFR1C, human beta-klotho and both human FGFR1C and human beta-klotho |
| JO3274B1 (ar) | 2009-12-24 | 2018-09-16 | Regeneron Pharma | أجسام مضادة بشرية للبروتين 4 المشابه لأجيوبيوتين البشري |
| US20120021409A1 (en) * | 2010-02-08 | 2012-01-26 | Regeneron Pharmaceuticals, Inc. | Common Light Chain Mouse |
| JO3756B1 (ar) | 2010-11-23 | 2021-01-31 | Regeneron Pharma | اجسام مضادة بشرية لمستقبلات الجلوكاجون |
| WO2012170977A1 (en) * | 2011-06-10 | 2012-12-13 | President And Fellows Of Harvard College | Modulation of pancreatic beta cell proliferation |
| AR087329A1 (es) | 2011-06-17 | 2014-03-19 | Regeneron Pharma | Anticuerpos humanos contra proteina 3 de tipo angiopoietina humana |
| WO2013106547A1 (en) * | 2012-01-10 | 2013-07-18 | President And Fellows Of Harvard College | Beta-cell replication promoting compounds and methods of their use |
| AU2013237760A1 (en) * | 2012-10-08 | 2014-04-24 | Biotime, Inc. | Differentiated progeny of clonal progenitor cell lines |
| WO2014183207A1 (en) * | 2013-05-17 | 2014-11-20 | Exerkine Corporation | Therapeutic method of treating metabolic syndrome |
| CN104164451A (zh) * | 2014-08-09 | 2014-11-26 | 高连如 | 一种治疗2型糖尿病的基因工程干细胞 |
| EP3201225B1 (en) * | 2014-10-03 | 2020-08-19 | NGM Biopharmaceuticals, Inc. | Angptl8 polypeptide and its use for treatment of conditions associated with elevated triglycerides |
| TW201713690A (zh) | 2015-08-07 | 2017-04-16 | 再生元醫藥公司 | 抗ａｎｇｐｔｌ８抗體及其用途 |
| MX386832B (es) | 2016-04-08 | 2025-03-19 | Regeneron Pharma | Inhibidor angptl8 e inhibidor angptl3 para usarse en el tratamiento de hiperlipidemia. |
| CN110036029A (zh) | 2016-11-17 | 2019-07-19 | 瑞泽恩制药公司 | 用抗angptl8抗体处理肥胖的方法 |
-
2016
- 2016-07-29 TW TW105124009A patent/TW201713690A/zh unknown
- 2016-08-04 EA EA201890453A patent/EA035088B1/ru not_active IP Right Cessation
- 2016-08-04 ES ES16770103T patent/ES2870031T3/es active Active
- 2016-08-04 KR KR1020187006505A patent/KR20180038020A/ko not_active Withdrawn
- 2016-08-04 US US15/228,398 patent/US10259870B2/en active Active
- 2016-08-04 HK HK18109700.2A patent/HK1250238A1/zh unknown
- 2016-08-04 AR ARP160102386A patent/AR105600A1/es unknown
- 2016-08-04 EP EP16770103.6A patent/EP3331908B1/en active Active
- 2016-08-04 MX MX2018001532A patent/MX394103B/es unknown
- 2016-08-04 CA CA2993976A patent/CA2993976A1/en not_active Abandoned
- 2016-08-04 JP JP2018506347A patent/JP7141333B2/ja active Active
- 2016-08-04 WO PCT/US2016/045535 patent/WO2017027316A1/en not_active Ceased
- 2016-08-04 CN CN201680046225.8A patent/CN107922478A/zh active Pending
- 2016-08-04 AU AU2016307430A patent/AU2016307430B2/en not_active Ceased
-
2018
- 2018-01-18 ZA ZA2018/00352A patent/ZA201800352B/en unknown
- 2018-01-31 IL IL257263A patent/IL257263A/en unknown
-
2021
- 2021-03-04 JP JP2021034006A patent/JP2021090449A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EA201890453A1 (ru) | 2018-07-31 |
| CA2993976A1 (en) | 2017-02-16 |
| KR20180038020A (ko) | 2018-04-13 |
| JP2021090449A (ja) | 2021-06-17 |
| IL257263A (en) | 2018-03-29 |
| TW201713690A (zh) | 2017-04-16 |
| AU2016307430B2 (en) | 2022-04-21 |
| JP7141333B2 (ja) | 2022-09-22 |
| EA035088B1 (ru) | 2020-04-27 |
| JP2018525383A (ja) | 2018-09-06 |
| HK1250238A1 (zh) | 2018-12-07 |
| AR105600A1 (es) | 2017-10-18 |
| EP3331908A1 (en) | 2018-06-13 |
| ES2870031T3 (es) | 2021-10-26 |
| US20170037124A1 (en) | 2017-02-09 |
| US10259870B2 (en) | 2019-04-16 |
| CN107922478A (zh) | 2018-04-17 |
| MX2018001532A (es) | 2018-03-15 |
| EP3331908B1 (en) | 2021-03-10 |
| ZA201800352B (en) | 2018-12-19 |
| WO2017027316A1 (en) | 2017-02-16 |
| AU2016307430A1 (en) | 2018-02-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX394103B (es) | Anticuerpos anti-angptl8 y usos de estos. | |
| EA201790377A1 (ru) | Антитела к глюкагону и их применения | |
| MX377712B (es) | Anticuerpos dirigidos contra il-33 y sus usos. | |
| SA519401522B1 (ar) | Lag-3 أجـسـام مـضـادة لـ وتـركـيـبـات | |
| JOP20190093A1 (ar) | أجسام مضادة لـ il-33 واستخداماتها | |
| MX2024010175A (es) | Moleculas de anticuerpo contra april y usos de las mismas. | |
| EA202090031A3 (ru) | Человеческие антитела против gfr3 и способы их применения | |
| MX2017013562A (es) | Reguladores de microbioma y usos relacionados de los mismos. | |
| EA201890725A1 (ru) | Агонисты фарнезоидного х-рецептора и их применение | |
| PH12015501493B1 (en) | Anti-pdgfr-beta antibodies and uses thereof | |
| MX385845B (es) | Usos y composiciones de la flagelina | |
| UY35682A (es) | Anticuerpos anti-activina a y usos de los mismos | |
| EA201992707A1 (ru) | Соединения и их применения для модуляции гемоглобина | |
| EA201501061A1 (ru) | Антитела к igf-1r с элиминированной способностью связываться с fcrn и их применение для лечения сосудистых глазных заболеваний | |
| EA201891594A1 (ru) | Антитела к il-17c | |
| EA201491522A1 (ru) | Способы лечения нарушения походки и/или равновесия у пациентов с рассеянным склерозом с использованием аминопиридина | |
| EA201501176A1 (ru) | Замещенные бензоксазолы | |
| HK1235409A1 (en) | Anti-glucagon antibodies and uses thereof |