MX392285B - Compuestos de glucolipidos y sus usos en el tratamiento de tumores. - Google Patents

Compuestos de glucolipidos y sus usos en el tratamiento de tumores.

Info

Publication number
MX392285B
MX392285B MX2018005828A MX2018005828A MX392285B MX 392285 B MX392285 B MX 392285B MX 2018005828 A MX2018005828 A MX 2018005828A MX 2018005828 A MX2018005828 A MX 2018005828A MX 392285 B MX392285 B MX 392285B
Authority
MX
Mexico
Prior art keywords
tumors
treatment
glycolipids
glycolipid compounds
compounds
Prior art date
Application number
MX2018005828A
Other languages
English (en)
Other versions
MX2018005828A (es
Inventor
Alexander Borisovich Tuzikov
Elena Yurievna Korchagina
Graham Griffiths
Nicolai Vladimirovich Bovin
Stephen Henry
Stephen Shaw
Original Assignee
Agalimmune Ltd
Kode Biotech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agalimmune Ltd, Kode Biotech Ltd filed Critical Agalimmune Ltd
Publication of MX2018005828A publication Critical patent/MX2018005828A/es
Publication of MX392285B publication Critical patent/MX392285B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7032—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyldiacylglycerides, lactobionic acid, gangliosides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
    • C07H5/06—Aminosugars
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)

Abstract

La invención se refiere a compuestos novedosos de glucolípidos y a composiciones farmacéuticas que comprenden dichos glucolípidos y a procedimientos para la preparación de dichos glucolípidos; la invención también se refiere a dichos glucolípidos para uso en el tratamiento de tumores y a métodos de tratamiento de tumores que usan dichos glucolípidos.
MX2018005828A 2015-11-11 2015-11-11 Compuestos de glucolipidos y sus usos en el tratamiento de tumores. MX392285B (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/RU2015/000766 WO2017082753A1 (en) 2015-11-11 2015-11-11 Glycolipid compounds and their uses in the treatment of tumours

Publications (2)

Publication Number Publication Date
MX2018005828A MX2018005828A (es) 2019-02-20
MX392285B true MX392285B (es) 2025-03-24

Family

ID=56117941

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018005828A MX392285B (es) 2015-11-11 2015-11-11 Compuestos de glucolipidos y sus usos en el tratamiento de tumores.

Country Status (13)

Country Link
US (1) US20180344805A1 (es)
EP (1) EP3374367A1 (es)
JP (1) JP6758375B2 (es)
KR (1) KR102517641B1 (es)
CN (1) CN108463466B (es)
AU (1) AU2015414272B2 (es)
BR (1) BR112018009646B1 (es)
CA (1) CA3004107C (es)
HK (1) HK1258843A1 (es)
IL (1) IL259205B (es)
MX (1) MX392285B (es)
RU (1) RU2719486C2 (es)
WO (1) WO2017082753A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023194941A1 (en) * 2022-04-08 2023-10-12 Kode Biotech Limited Large scale production of n-acetyllactosamine derivatives
KR20250008358A (ko) * 2023-07-07 2025-01-14 주식회사 고바이오랩 락토바실러스 가세리 균주에서 유래한 당지질

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7820628B2 (en) * 2005-02-22 2010-10-26 University Of Massachusetts Medical School Tumor lesion regression and conversion in situ into autologous tumor vaccines by compositions that result in anti-Gal antibody binding
WO2009048343A1 (en) * 2007-10-12 2009-04-16 Nicolai Bovin Functional lipid constructs
MX360254B (es) 2011-03-10 2018-10-26 Pfizer Combinacion de terapias inmunomoduladoras local y sistemica para tratamiento mejorado del cancer.
JP6709797B2 (ja) * 2014-11-21 2020-06-17 ボヴィン、ニコライ ウラジミロヴィチＢＯＶＩＮ，Ｎｉｃｏｌａｉ Ｖｌａｄｉｍｉｒｏｖｉｃｈ 多価リガンド−脂質構築物

Also Published As

Publication number Publication date
US20180344805A1 (en) 2018-12-06
IL259205A (en) 2018-07-31
RU2719486C2 (ru) 2020-04-17
HK1258843A1 (zh) 2019-11-22
JP6758375B2 (ja) 2020-09-23
CA3004107C (en) 2023-10-17
RU2018121273A3 (es) 2019-12-13
AU2015414272B2 (en) 2021-04-22
BR112018009646A2 (en) 2018-12-11
KR20180099651A (ko) 2018-09-05
CN108463466B (zh) 2021-07-09
MX2018005828A (es) 2019-02-20
BR112018009646B1 (pt) 2020-03-31
CA3004107A1 (en) 2017-05-18
JP2018533616A (ja) 2018-11-15
AU2015414272A1 (en) 2018-04-26
KR102517641B1 (ko) 2023-04-05
CN108463466A (zh) 2018-08-28
RU2018121273A (ru) 2019-12-13
IL259205B (en) 2021-06-30
EP3374367A1 (en) 2018-09-19
WO2017082753A1 (en) 2017-05-18

Similar Documents

Publication Publication Date Title
MX2018005315A (es) Composiciones y metodos para el tratamiento del cancer.
MX2020011104A (es) Composiciones farmaceuticas de compuestos terapeuticamente activos y sus metodos de uso.
CL2015002194A1 (es) Inhbidores de erk y sus usos
MX395007B (es) Inhibidores de tirosina-cinasas
MX377877B (es) Composiciones de solución sólida y su uso en el tratamiento del dolor intenso.
EP3424505A4 (en) PREPARATION AND COMPOSITION FOR THE TREATMENT OF MALIGNANT TUMORS
CL2015002628A1 (es) Compuestos de heteroarilo y sus usos.
PT3377516T (pt) Composição para o tratamento do cancro
CL2014001865A1 (es) Compuestos derivados de fosfatos; procedimiento de preparacion; composiciones farmaceuticas que los contienen y uso en el tratamiento del cancer.
UA119458C2 (uk) Сполуки піридину пладієноліду та способи застосування
EA201591925A1 (ru) Терапевтические композиции и их применение
MX395231B (es) Compuestos eficaces en el tratamiento de la hepatotoxicidad y enfermedades de hígado graso, y uso de los mismos.
MX378168B (es) Un extracto de indigo naturalis y un proceso para preparar el mismo.
BR112016017112A2 (pt) Composições de apilimod e métodos de uso das mesmas
HUE047540T2 (hu) Javított allogén dendritikus sejtek rák kezelésében történõ alkalmazásra
HUE055132T2 (hu) Virulenciában gyengített baktériumok rosszindulatú szolid tumorok kezelésére
MX391040B (es) Formulacion de alta concentracion.
CL2016001937A1 (es) Compuestos de benzopirano funcionalizados y uso de los mismos
IT201600084470A1 (it) Composizione per uso nel trattamento del disturbo depressivo maggiore
IT201600101413A1 (it) Composizione liquida per uso nel trattamento del reflusso gastroesofageo
BR112017024908A2 (pt) usos terapêuticos da 4-cloroquinurenina
IL248735B (en) Preparations containing glycolipid for use in the treatment of tumors
PH12016501838A1 (en) Compounds and their methods of use
MX392285B (es) Compuestos de glucolipidos y sus usos en el tratamiento de tumores.
CL2018002848A1 (es) Formulaciones liquidas de fosfoplatino