MX391141B - Anticuerpos anti-ceramida. - Google Patents

Anticuerpos anti-ceramida.

Info

Publication number
MX391141B
MX391141B MX2017001686A MX2017001686A MX391141B MX 391141 B MX391141 B MX 391141B MX 2017001686 A MX2017001686 A MX 2017001686A MX 2017001686 A MX2017001686 A MX 2017001686A MX 391141 B MX391141 B MX 391141B
Authority
MX
Mexico
Prior art keywords
antibodies
ceramide
disclosed
ceramide antibodies
apoptosis
Prior art date
Application number
MX2017001686A
Other languages
English (en)
Spanish (es)
Other versions
MX2017001686A (es
Inventor
Jimmy Rotolo
Richard Kolesnick
Original Assignee
Memorial Sloan Kettering Cancer Center
Ceram Therapeutics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Memorial Sloan Kettering Cancer Center, Ceram Therapeutics filed Critical Memorial Sloan Kettering Cancer Center
Publication of MX2017001686A publication Critical patent/MX2017001686A/es
Publication of MX391141B publication Critical patent/MX391141B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/74Inducing cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Transplantation (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
MX2017001686A 2014-08-07 2015-08-07 Anticuerpos anti-ceramida. MX391141B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462034453P 2014-08-07 2014-08-07
PCT/US2015/044144 WO2016022883A1 (en) 2014-08-07 2015-08-07 Anti-ceramide antibodies

Publications (2)

Publication Number Publication Date
MX2017001686A MX2017001686A (es) 2017-09-01
MX391141B true MX391141B (es) 2025-03-21

Family

ID=55264608

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017001686A MX391141B (es) 2014-08-07 2015-08-07 Anticuerpos anti-ceramida.

Country Status (12)

Country Link
US (4) US10450385B2 (enExample)
EP (1) EP3177650B1 (enExample)
JP (1) JP6670297B2 (enExample)
KR (1) KR102296416B1 (enExample)
CN (1) CN107074949B (enExample)
AU (1) AU2015300902B2 (enExample)
CA (1) CA2957415C (enExample)
IL (1) IL250374B (enExample)
MX (1) MX391141B (enExample)
RU (1) RU2717651C2 (enExample)
SG (1) SG11201700787XA (enExample)
WO (1) WO2016022883A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2017228474C1 (en) 2016-03-04 2024-03-28 Abmuno Therapeutics Llc Antibodies to TIGIT
CN110121507B (zh) * 2016-12-23 2024-04-05 蓝鳍生物医药公司 抗sez6l2抗体和抗体药物缀合物
WO2020231629A1 (en) 2019-05-16 2020-11-19 Snake River Bioscience, Inc. Compositions and methods for the treatment of major depressive disorder
KR102808557B1 (ko) * 2019-06-06 2025-05-14 자코바이오 파마슈티칼스 컴퍼니 리미티드 Cd73에 특이적인 결합 분자 및 결합 분자의 용도
US10975169B1 (en) 2019-09-27 2021-04-13 Memorial Sloan Kettering Cancer Center Methods for treating diabetic retinopathy using anti-ceramide monoclonal antibody 2A2
KR102245082B1 (ko) * 2020-02-14 2021-04-26 단국대학교 천안캠퍼스 산학협력단 치주인대전구세포 표면에 특이적으로 결합하는 두 가지 IgG 타입 단일클론항체 LG43, LG73 및 그의 용도
CA3172201A1 (en) * 2020-03-18 2021-09-23 Arthur Tinkelenberg Anti-ceramide antibodies
KR20230019152A (ko) 2020-06-02 2023-02-07 아르커스 바이오사이언시즈 인코포레이티드 Tigit에 대한 항체
BR112023018758A2 (pt) * 2021-03-16 2023-11-28 Univ Michigan State Intensificação de cicatrização de ferida com anticorpos anticeramida
WO2024226646A2 (en) * 2023-04-25 2024-10-31 Memorial Sloan-Kettering Cancer Center Dlk1 -targeting antibodies and uses thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4676980A (en) 1985-09-23 1987-06-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Target specific cross-linked heteroantibodies
JPH02128697A (ja) * 1988-11-09 1990-05-17 Hoechst Japan Ltd 抗フコシルセラミドモノクローナル抗体
US7897753B2 (en) * 2002-02-20 2011-03-01 Sirna Therapeutics, Inc. RNA interference mediated inhibition of XIAP gene expression using short interfering nucleic acid (siNA)
RU2310393C1 (ru) * 2006-02-16 2007-11-20 ФГУ Научно-исследовательский институт по изучению лепры Федерального агентства по здравоохранению и социальному развитию Российской Федерации Способ прогнозирования обострений лепрозных невропатий у больных лепрой
EP2152287B1 (en) * 2007-05-06 2014-04-02 Sloan Kettering Institute For Cancer Research Methods for treating and preventing gi syndrome and graft versus host disease
US9163091B2 (en) * 2007-05-30 2015-10-20 Lpath, Inc. Compositions and methods for binding lysophosphatidic acid
US8410251B2 (en) * 2008-06-20 2013-04-02 National University Corporation Okayama University Antibody against calcified globule and use of the same
KR101050829B1 (ko) 2008-10-02 2011-07-20 서울대학교산학협력단 항 pd-1 항체 또는 항 pd-l1 항체를 포함하는 항암제
JP5812418B2 (ja) * 2009-04-17 2015-11-11 イムナス・ファーマ株式会社 Aβオリゴマーに特異的に結合する抗体およびその利用
FR2971250A1 (fr) 2011-02-07 2012-08-10 Univ Nantes Anticorps anti-gb3 utiles dans le traitement des maladies associees a l'angiogenese
KR101256351B1 (ko) 2011-11-22 2013-04-19 김석진 필터 삽입공을 갖는 카메라 후드
MX357505B (es) * 2012-02-21 2018-07-12 Toray Industries Composicion farmaceutica para el tratamiento y/o prevencion del cancer.
DK2854850T3 (da) * 2012-05-25 2021-08-30 Sloan Kettering Inst Cancer Res Sammensætninger til behandling eller forebyggelse af strålingssygdom og gi-syndrom
CA3172201A1 (en) * 2020-03-18 2021-09-23 Arthur Tinkelenberg Anti-ceramide antibodies

Also Published As

Publication number Publication date
US10450385B2 (en) 2019-10-22
RU2717651C2 (ru) 2020-03-24
US20250197524A1 (en) 2025-06-19
EP3177650A1 (en) 2017-06-14
JP2017527544A (ja) 2017-09-21
IL250374B (en) 2021-04-29
NZ728981A (en) 2024-03-22
AU2015300902A1 (en) 2017-03-02
CN107074949A (zh) 2017-08-18
US20230416409A1 (en) 2023-12-28
US20190389970A1 (en) 2019-12-26
EP3177650A4 (en) 2018-01-03
EP3177650B1 (en) 2025-11-05
US20170335014A1 (en) 2017-11-23
JP6670297B2 (ja) 2020-03-18
IL250374A0 (en) 2017-03-30
CA2957415C (en) 2021-07-13
US11447572B2 (en) 2022-09-20
RU2017105596A3 (enExample) 2019-04-17
WO2016022883A1 (en) 2016-02-11
CN107074949B (zh) 2021-06-15
BR112017002433A2 (pt) 2017-11-28
MX2017001686A (es) 2017-09-01
KR102296416B1 (ko) 2021-09-01
KR20170066327A (ko) 2017-06-14
AU2015300902B2 (en) 2020-05-28
CA2957415A1 (en) 2016-02-11
RU2017105596A (ru) 2018-09-07
SG11201700787XA (en) 2017-02-27

Similar Documents

Publication Publication Date Title
MX391141B (es) Anticuerpos anti-ceramida.
PH12016501894B1 (en) Anti-ox40 antibodies and methods of use
DK3458478T3 (da) Anti-pd-1- og anti-lag3-antistoffer til cancerbehandling
IL259924A (en) Combination of anti-pd-1 antibodies and bispecific anti-cd20/anti-cd3 antibodies to treat cancer
PH12017500322A1 (en) Anti-her2 antibodies and immunoconjugates
HUE061842T2 (hu) A rák kezelésének módszerei anti-PD-1 antitestekkel
EA201790569A1 (ru) Антитела и иммуноконъюгаты против cll-1
GEP20217331B (en) Anti-tigit antibodies
IL251537A0 (en) Human anti-ox40 antibodies and their uses
MX388181B (es) Anticuerpos anti-pd-1.
DK3157959T3 (da) Monoklonale antistoffer mod her2-epitop og fremgangsmåder til anvendelse deraf
MX2022002364A (es) Anticuerpos anti-pd-l1.
DK3307322T3 (da) Humaniserede anti-cd40-antistoffer og anvendelser deraf
HUE050831T2 (hu) Daganatkezelési módszerek a CD3XCD20 bispecifikus antitest használatával
EA201790984A1 (ru) Анти-cd79b антитела и способы их применения
EP3244926C0 (en) TREATMENT OF CANCER WITH ANTI-LAP MONOCLONAL ANTIBODIES
DK3119808T3 (da) Antistofsammensætninger til tumorbehandling
EA201691610A1 (ru) Анти-jagged1 антитела и способы применения
IL248402A0 (en) Humanized antibodies against ceacam1
DK3280440T3 (da) Humaniserede anti-c1s-antistoffer og fremgangsmåder til anvendelse deraf
NZ730186A (en) Humanized anti-hepcidin antibodies and uses thereof
BR112018002382A8 (pt) Novos anticorpos anti-gvpi humano e usos dos mesmos
CL2016001753A1 (es) Anticuerpo monoclonal humanizado que se une específicamente a netrina-1, composiciones farmacéuticas y usos del anticuerpo para el tratamiento del cáncer
DK3154583T3 (da) Humane monoklonale antistoffer mod gangliosid gd2
IL252535A0 (en) A combination of cs1 and pd1 antibodies for the treatment of cancer (myeloma)