MX388705B - Dispositivo y metodo para realizar conexiones asepticas. - Google Patents

Dispositivo y metodo para realizar conexiones asepticas.

Info

Publication number
MX388705B
MX388705B MX2017011039A MX2017011039A MX388705B MX 388705 B MX388705 B MX 388705B MX 2017011039 A MX2017011039 A MX 2017011039A MX 2017011039 A MX2017011039 A MX 2017011039A MX 388705 B MX388705 B MX 388705B
Authority
MX
Mexico
Prior art keywords
drug
fluid pathway
film
fluid
piercing member
Prior art date
Application number
MX2017011039A
Other languages
English (en)
Other versions
MX2017011039A (es
Inventor
Antonio Ubach
Daniel S Codd
Danielle Feldman
Ian B Hanson
Kevin L Bokelman
Lawton Laurence
Matthew J Clemente
Rajan Ramaswamy
Scott Beaver
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of MX2017011039A publication Critical patent/MX2017011039A/es
Publication of MX388705B publication Critical patent/MX388705B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/162Needle sets, i.e. connections by puncture between reservoir and tube ; Connections between reservoir and tube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006Piercing means
    • A61J1/201Piercing means having one piercing end
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048Connecting means
    • A61J1/2051Connecting means having tap means, e.g. tap means activated by sliding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10Tube connectors; Tube couplings
    • A61M39/16Tube connectors; Tube couplings having provision for disinfection or sterilisation
    • A61M39/18Methods or apparatus for making the connection under sterile conditions, i.e. sterile docking
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/1413Modular systems comprising interconnecting elements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/14244Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/145Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/1456Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir comprising a piston rod to be moved into the reservoir, e.g. the piston rod is part of the removable reservoir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/162Needle sets, i.e. connections by puncture between reservoir and tube ; Connections between reservoir and tube
    • A61M5/1626Needle protectors therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/1406Septums, pierceable membranes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/14244Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • A61M2005/14252Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type with needle insertion means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A61M2005/1585Needle inserters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2455Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened
    • A61M5/2466Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened by piercing without internal pressure increase
    • A61M2005/2474Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened by piercing without internal pressure increase with movable piercing means, e.g. ampoule remains fixed or steady
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/34Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
    • A61M2005/341Constructions for connecting the needle, e.g. to syringe nozzle or needle hub angularly adjustable or angled away from the axis of the injector
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/02General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0216Materials providing elastic properties, e.g. for facilitating deformation and avoid breaking
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/18General characteristics of the apparatus with alarm
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/58Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/581Means for facilitating use, e.g. by people with impaired vision by audible feedback
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/58Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/587Lighting arrangements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)

Abstract

La presente invención proporciona dispositivos y métodos para establecer conexiones asépticas entre dos o más componentes o subconjuntos. Los dispositivos se pueden utilizar en dispositivos médicos tales como bombas para el suministro de fármacos (10). En algunas modalidades, se realiza una conexión entre un envase para fármacos (50, 1050, 2050) y un ensamblaje de conexión de la vía de fluido (300, 1300; 2300). El ensamblaje de conexión de la vía de fluido puede incluir un punto de conexión (312, 1312, 2312), un miembro perforador (316, 1316,2316), y un retenedor del miembro perforador (314, 1314, 2314). El ensamblaje puede incluir además una primera película (318, 1318, 2318) que cubre una cavidad (312A, 1312A, 2312A), manteniendo así la condición aséptica de la cavidad. El envase para fármacos puede albergar un fármaco fluido e incluye un sello perforable (326, 1326, 2326). Una segunda película (322, 1322, 2322) puede cubrir un hueco (328, 1328, 2328) formado por el sello y mantiene así la condición aséptica del interior de la cámara. Se puede hacer que el miembro perforador perfore la primera y segunda película y que el sello perforable abra una vía de fluido para el suministro del fármaco fluido a través del ensamblaje de conexión de la vía de fluido.
MX2017011039A 2015-03-02 2016-03-02 Dispositivo y metodo para realizar conexiones asepticas. MX388705B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562127021P 2015-03-02 2015-03-02
US201562148082P 2015-04-15 2015-04-15
PCT/US2016/020486 WO2016141082A1 (en) 2015-03-02 2016-03-02 Device and method for making aseptic connections

Publications (2)

Publication Number Publication Date
MX2017011039A MX2017011039A (es) 2018-03-15
MX388705B true MX388705B (es) 2025-03-20

Family

ID=55521869

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2017011039A MX388705B (es) 2015-03-02 2016-03-02 Dispositivo y metodo para realizar conexiones asepticas.
MX2021015409A MX2021015409A (es) 2015-03-02 2017-08-28 Dispositivo y metodo para realizar conexiones asepticas.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2021015409A MX2021015409A (es) 2015-03-02 2017-08-28 Dispositivo y metodo para realizar conexiones asepticas.

Country Status (8)

Country Link
US (2) US10569014B2 (es)
EP (2) EP3265146B1 (es)
JP (3) JP6752808B2 (es)
AU (3) AU2016226293B2 (es)
CA (2) CA2978017C (es)
ES (1) ES2856759T3 (es)
MX (2) MX388705B (es)
WO (1) WO2016141082A1 (es)

Families Citing this family (145)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE480278T1 (de) 2005-09-12 2010-09-15 Unomedical As Einfürungssystem für ein infusionsset mit einem ersten und zweiten federeinheit
US8417311B2 (en) 2008-09-12 2013-04-09 Optiscan Biomedical Corporation Fluid component analysis system and method for glucose monitoring and control
US9173997B2 (en) 2007-10-02 2015-11-03 Medimop Medical Projects Ltd. External drug pump
CA2702116C (en) 2007-10-10 2021-01-05 Optiscan Biomedical Corporation Fluid component analysis system and method for glucose monitoring and control
US7959598B2 (en) 2008-08-20 2011-06-14 Asante Solutions, Inc. Infusion pump systems and methods
US8157769B2 (en) 2009-09-15 2012-04-17 Medimop Medical Projects Ltd. Cartridge insertion assembly for drug delivery system
CA2792138A1 (en) 2010-03-30 2011-10-06 Unomedical A/S Medical device
US10194938B2 (en) 2011-03-14 2019-02-05 UnoMedical, AS Inserter system with transport protection
MX352613B (es) 2011-09-13 2017-12-01 Unitract Syringe Pty Ltd Conexión estéril de vía de fluido para contenedores de fármacos para bombas de suministro de fármacos.
EP2583715A1 (en) 2011-10-19 2013-04-24 Unomedical A/S Infusion tube system and method for manufacture
RS65875B1 (sr) 2012-03-30 2024-09-30 Insulet Corp Sredstvo za isporučivanje tečnosti sa alatom za transkutani pristup, mehanizmom za inserciju i praćenje nivoa glukoze u krvi za istovremenu upotrebu
US9421323B2 (en) 2013-01-03 2016-08-23 Medimop Medical Projects Ltd. Door and doorstop for portable one use drug delivery apparatus
US9561324B2 (en) 2013-07-19 2017-02-07 Bigfoot Biomedical, Inc. Infusion pump system and method
GB2523989B (en) 2014-01-30 2020-07-29 Insulet Netherlands B V Therapeutic product delivery system and method of pairing
CN111905188B (zh) 2015-02-18 2022-07-22 英赛罗公司 流体输送和输注装置及其使用方法
BR112017019269B1 (pt) 2015-03-09 2022-11-29 Amgen Inc Mecanismos de acionamento para uso com um recipiente de drogas e bomba de distribuição de drogas
CN107635527B (zh) 2015-03-10 2021-04-23 里珍纳龙药品有限公司 无菌刺穿系统和方法
CN113181477B (zh) 2015-06-04 2023-07-14 麦迪麦珀医疗工程有限公司 用于药物释放装置的筒插入
USD794771S1 (en) * 2015-07-10 2017-08-15 Unitract Syringe Pty Ltd. Drug delivery pump
US10039913B2 (en) * 2015-07-30 2018-08-07 Carefusion 303, Inc. Tamper-resistant cap
US10576207B2 (en) 2015-10-09 2020-03-03 West Pharma. Services IL, Ltd. Angled syringe patch injector
JP7044708B2 (ja) 2015-10-09 2022-03-30 ウェスト ファーマ サービシーズ イスラエル リミテッド カスタマイズシリンジの充填方法
WO2017091584A1 (en) 2015-11-25 2017-06-01 Insulet Corporation Wearable medication delivery device
US10874799B2 (en) * 2015-11-27 2020-12-29 Sanofi-Aventis Deutschland Gmbh Medicament delivery device
WO2017123525A1 (en) 2016-01-13 2017-07-20 Bigfoot Biomedical, Inc. User interface for diabetes management system
US10806859B2 (en) 2016-01-14 2020-10-20 Bigfoot Biomedical, Inc. Adjusting insulin delivery rates
HK1256995A1 (zh) 2016-01-14 2019-10-11 Bigfoot Biomedical, Inc. 药物输送设备、系统和方法中的阻塞解决方案
WO2017125817A1 (en) 2016-01-19 2017-07-27 Unomedical A/S Cannula and infusion devices
USD857191S1 (en) * 2016-01-21 2019-08-20 Becton, Dickinson And Company Wearable drug delivery device
WO2017127215A1 (en) 2016-01-21 2017-07-27 Medimop Medical Projects Ltd. Needle insertion and retraction mechanism
CN109219456B (zh) 2016-01-21 2020-05-15 西医药服务以色列有限公司 自动注射器中的力牵制
CN113041432B (zh) 2016-01-21 2023-04-07 西医药服务以色列有限公司 包括视觉指示物的药剂输送装置
US10363342B2 (en) 2016-02-04 2019-07-30 Insulet Corporation Anti-inflammatory cannula
JOP20170042B1 (ar) 2016-02-12 2022-09-15 Amgen Inc وسيلة توصيل عقار، طريقة تصنيعه وطريقة استخدامه
US11389597B2 (en) 2016-03-16 2022-07-19 West Pharma. Services IL, Ltd. Staged telescopic screw assembly having different visual indicators
JP7074684B2 (ja) 2016-04-08 2022-05-24 アムジエン・インコーポレーテツド 薬物送達デバイス、製造方法、及び使用方法
US12383166B2 (en) 2016-05-23 2025-08-12 Insulet Corporation Insulin delivery system and methods with risk-based set points
US11103652B2 (en) 2016-06-02 2021-08-31 West Pharma. Services IL, Ltd. Three position needle retraction
EP3260146A1 (en) * 2016-06-23 2017-12-27 TecPharma Licensing AG A coupling mechanism for a medication delivery device
US11730892B2 (en) 2016-08-01 2023-08-22 West Pharma. Services IL, Ltd. Partial door closure prevention spring
US11338090B2 (en) 2016-08-01 2022-05-24 West Pharma. Services IL, Ltd. Anti-rotation cartridge pin
JP2019524302A (ja) * 2016-08-08 2019-09-05 ユーエヌエル ホールディングス エルエルシーUNL Holdings LLC 薬剤送達デバイスおよび流体流路を接続するための方法
US10765807B2 (en) 2016-09-23 2020-09-08 Insulet Corporation Fluid delivery device with sensor
GB2556633A (en) * 2016-11-18 2018-06-06 Owen Mumford Ltd Medicament delivery device
CN109862863A (zh) * 2016-11-21 2019-06-07 泰尔茂株式会社 药液填充单元、药液填充组件以及填充接合器
ES2985905T3 (es) 2016-11-22 2024-11-07 Lts Device Tech Ltd Aparato para suministrar una sustancia terapéutica
US11096624B2 (en) 2016-12-12 2021-08-24 Bigfoot Biomedical, Inc. Alarms and alerts for medication delivery devices and systems
US10583250B2 (en) 2017-01-13 2020-03-10 Bigfoot Biomedical, Inc. System and method for adjusting insulin delivery
US10500334B2 (en) 2017-01-13 2019-12-10 Bigfoot Biomedical, Inc. System and method for adjusting insulin delivery
US11033682B2 (en) 2017-01-13 2021-06-15 Bigfoot Biomedical, Inc. Insulin delivery methods, systems and devices
US10881792B2 (en) 2017-01-13 2021-01-05 Bigfoot Biomedical, Inc. System and method for adjusting insulin delivery
EP3568860B1 (en) 2017-01-13 2025-12-10 Insulet Corporation Insulin delivery methods, systems and devices
US10758675B2 (en) 2017-01-13 2020-09-01 Bigfoot Biomedical, Inc. System and method for adjusting insulin delivery
US10933192B2 (en) 2017-01-31 2021-03-02 Unl Holdings Llc Aseptic connections for drug delivery devices
WO2018151890A1 (en) 2017-02-17 2018-08-23 Amgen Inc. Drug delivery device with sterile fluid flowpath and related method of assembly
WO2018156548A1 (en) * 2017-02-22 2018-08-30 Insulet Corporation Needle insertion mechanisms for drug containers
IL308643B2 (en) 2017-05-05 2025-02-01 Regeneron Pharma Auto-injector
EP3630226B1 (en) * 2017-05-30 2025-10-22 West Pharma. Services Il, Ltd. Modular drive train for wearable injector
JP7649105B2 (ja) * 2017-07-21 2025-03-19 アムジエン・インコーポレーテツド 薬物容器のためのガス透過性シーリング部材及び組立方法
MA49676A (fr) 2017-07-25 2020-06-03 Amgen Inc Dispositif d'administration de médicament doté d'un système d'accès à un récipient et procédé d'assemblage associé
EP3672681B1 (en) 2017-08-22 2024-09-25 Roche Diabetes Care GmbH Self-sealing septum
US10898656B2 (en) 2017-09-26 2021-01-26 Insulet Corporation Needle mechanism module for drug delivery device
ES2971450T3 (es) 2017-10-06 2024-06-05 Amgen Inc Dispositivo de administración de fármacos con conjunto de enclavamiento y procedimiento de montaje correspondiente
US11464903B2 (en) 2017-10-09 2022-10-11 Amgen Inc. Drug delivery device with drive assembly and related method of assembly
CN118576827A (zh) * 2017-10-16 2024-09-03 贝克顿·迪金森公司 流体转移系统
EP3707075A1 (en) 2017-11-06 2020-09-16 Amgen Inc. Fill-finish assemblies and related methods
US10869961B2 (en) 2017-11-06 2020-12-22 Sorrel Medical Ltd. Local disinfection for drug delivery system
US10869960B2 (en) * 2017-11-06 2020-12-22 Sorrel Medical Ltd Local disinfection for prefilled drug delivery system
US11147931B2 (en) 2017-11-17 2021-10-19 Insulet Corporation Drug delivery device with air and backflow elimination
JP7402799B2 (ja) 2017-12-22 2023-12-21 ウェスト ファーマ サービシーズ イスラエル リミテッド サイズの異なるカートリッジを利用可能な注射器
WO2019150145A1 (en) * 2018-01-31 2019-08-08 Unitract Syringe Pty Ltd Aseptic connections for drug delivery devices
USD928199S1 (en) 2018-04-02 2021-08-17 Bigfoot Biomedical, Inc. Medication delivery device with icons
US11565043B2 (en) 2018-05-04 2023-01-31 Insulet Corporation Safety constraints for a control algorithm based drug delivery system
US12562251B1 (en) 2018-05-09 2026-02-24 Bigfoot Biomedical, Inc. Computing architecture for assuring the provenance of medication therapy related parameters, and related systems, methods and devices
KR102776224B1 (ko) * 2018-05-11 2025-03-10 브리스톨-마이어스 스큅 컴퍼니 조합 치료법의 전달을 위한 장치 및 시스템
EP3603700A1 (en) 2018-07-30 2020-02-05 Tecpharma Licensing AG Needle insertion and retraction mechanism
AU2019347755B2 (en) 2018-09-28 2023-02-02 Insulet Corporation Activity mode for artificial pancreas system
EP3632487B1 (en) * 2018-10-05 2024-06-12 LTS Device Technologies Ltd Triggering sequence
EP3864668A1 (en) 2018-10-11 2021-08-18 Insulet Corporation Event detection for drug delivery system
USD920343S1 (en) 2019-01-09 2021-05-25 Bigfoot Biomedical, Inc. Display screen or portion thereof with graphical user interface associated with insulin delivery
WO2020187876A1 (en) * 2019-03-20 2020-09-24 Sanofi Container retaining member, drug delivery device and method
CA3141608A1 (en) 2019-05-20 2020-11-26 Unomedical A/S Rotatable infusion device and methods thereof
US11338082B2 (en) * 2019-09-04 2022-05-24 BloQ Pharma, Inc. Variable rate dispenser with aseptic spike connector assembly
US11801344B2 (en) 2019-09-13 2023-10-31 Insulet Corporation Blood glucose rate of change modulation of meal and correction insulin bolus quantity
US11935637B2 (en) 2019-09-27 2024-03-19 Insulet Corporation Onboarding and total daily insulin adaptivity
EP4069082B1 (en) 2019-12-06 2024-06-05 Insulet Corporation Techniques and devices providing adaptivity and personalization in diabetes treatment
GB201918663D0 (en) * 2019-12-17 2020-01-29 Oribiotech Ltd A connector
JP2023507411A (ja) * 2019-12-19 2023-02-22 ヤンセン バイオテツク,インコーポレーテツド 向きによらない液体薬剤アクセシビリティーを有するポンプ
US11833329B2 (en) 2019-12-20 2023-12-05 Insulet Corporation Techniques for improved automatic drug delivery performance using delivery tendencies from past delivery history and use patterns
JP7512395B2 (ja) 2020-01-06 2024-07-08 インスレット コーポレイション 持続する残差に基づく食事および/または運動行為の予測
EP4100958A1 (en) 2020-02-03 2022-12-14 Insulet Corporation Use of fuzzy logic in predicting user behavior affecting blood glucose concentration
US11551802B2 (en) 2020-02-11 2023-01-10 Insulet Corporation Early meal detection and calorie intake detection
US11547800B2 (en) 2020-02-12 2023-01-10 Insulet Corporation User parameter dependent cost function for personalized reduction of hypoglycemia and/or hyperglycemia in a closed loop artificial pancreas system
US11986630B2 (en) 2020-02-12 2024-05-21 Insulet Corporation Dual hormone delivery system for reducing impending hypoglycemia and/or hyperglycemia risk
US11324889B2 (en) 2020-02-14 2022-05-10 Insulet Corporation Compensation for missing readings from a glucose monitor in an automated insulin delivery system
US12495994B2 (en) 2020-02-20 2025-12-16 Insulet Corporation Meal bolus subcategories in model based insulin therapy
US11607493B2 (en) 2020-04-06 2023-03-21 Insulet Corporation Initial total daily insulin setting for user onboarding
US12121700B2 (en) 2020-07-22 2024-10-22 Insulet Corporation Open-loop insulin delivery basal parameters based on insulin delivery records
US11684716B2 (en) 2020-07-31 2023-06-27 Insulet Corporation Techniques to reduce risk of occlusions in drug delivery systems
US12569619B2 (en) 2020-09-21 2026-03-10 Insulet Corporation Techniques for determining automated insulin delivery dosages
WO2022061219A1 (en) * 2020-09-21 2022-03-24 Boston Scientific Scimed, Inc. Fluid pressure indicators for medical devices
US12115351B2 (en) 2020-09-30 2024-10-15 Insulet Corporation Secure wireless communications between a glucose monitor and other devices
EP4696344A3 (en) 2020-09-30 2026-04-15 Insulet Corporation Drug delivery device with integrated optical-based glucose monitor
WO2022104270A1 (en) * 2020-11-16 2022-05-19 West Pharmaceutical Services, Inc. Connection system for a drug delivery device
US11160925B1 (en) 2021-01-29 2021-11-02 Insulet Corporation Automatic drug delivery system for delivery of a GLP-1 therapeutic
US11872369B1 (en) 2021-02-18 2024-01-16 Fresenius Kabi Deutschland Gmbh Wearable medicament delivery device with leakage and skin contact sensing and method of use thereof
US11311666B1 (en) 2021-02-18 2022-04-26 Fresenius Kabi Deutschland Gmbh Modular wearable medicament delivery device and method of use thereof
US11464902B1 (en) 2021-02-18 2022-10-11 Fresenius Kabi Deutschland Gmbh Wearable medicament delivery device with compressible reservoir and method of use thereof
US11406755B1 (en) 2021-02-19 2022-08-09 Fresenius Kabi Deutschland Gmbh Sensing fluid flow irregularities in an on-body injector
US11497847B1 (en) 2021-02-19 2022-11-15 Fresenius Kabi Deutschland Gmbh Wearable injector with adhesive substrate
US11607505B1 (en) 2021-02-19 2023-03-21 Fresenius Kabi Deutschland Gmbh Wearable injector with sterility sensors
US11413394B1 (en) 2021-02-19 2022-08-16 Fresenius Kabi Deutschland Gmbh Display for wearable drug delivery device
US11426523B1 (en) 2021-02-19 2022-08-30 Fresenius Kabi Deutschland Gmbh Drug delivery assembly including a removable cartridge
US11344682B1 (en) 2021-02-19 2022-05-31 Fresenius Kabi Deutschland Gmbh Drug supply cartridge with visual use indicator and delivery devices that use the same
US11633537B1 (en) 2021-02-19 2023-04-25 Fresenius Kabi Deutschland Gmbh Drug delivery assembly including a pre-filled cartridge
EP4305636A1 (en) 2021-03-10 2024-01-17 Insulet Corporation A medicament delivery device with an adjustable and piecewise analyte level cost component to address persistent positive analyte level excursions
US11904140B2 (en) 2021-03-10 2024-02-20 Insulet Corporation Adaptable asymmetric medicament cost component in a control system for medicament delivery
WO2022197608A1 (en) * 2021-03-14 2022-09-22 West Pharmaceutical Services, Inc. Connection system and active sterilizer for a drug delivery device
EP4059539A1 (en) * 2021-03-15 2022-09-21 Sensile Medical AG Method of producing a drug delivery device
EP4059541A1 (en) * 2021-03-15 2022-09-21 Sensile Medical AG Drug delivery device
EP4059537A1 (en) * 2021-03-15 2022-09-21 Sensile Medical AG Drug delivery device
US12592306B2 (en) 2021-04-28 2026-03-31 Insulet Corporation Devices and methods for initialization of drug delivery devices using measured analyte sensor information
US11529459B1 (en) 2021-04-30 2022-12-20 Fresenius Kabi Deutschland Gmbh Wearable injector with adhesive module
US11351300B1 (en) 2021-04-30 2022-06-07 Fresenius Kabl Deutschland GmbH Drug dispensing system with replaceable drug supply cartridges
US11419976B1 (en) 2021-04-30 2022-08-23 Fresenius Kabi Deutschland Gmbh Wearable drug delivery device with pressurized fluid dispensing
US11504470B1 (en) 2021-04-30 2022-11-22 Fresenius Kabi Deutschland Gmbh Deformable drug reservoir for wearable drug delivery device
US11717608B1 (en) 2021-05-03 2023-08-08 Fresenius Kabi Deutschland Gmbh Drug delivery assembly including an adhesive pad
US11484646B1 (en) 2021-05-04 2022-11-01 Fresenius Kabi Deutschland Gmbh Sealing systems for a reservoir of an on-body injector
US12496398B2 (en) 2021-05-28 2025-12-16 Insulet Corporation Threshold based automatic glucose control response
IT202100014615A1 (it) 2021-06-04 2022-12-04 Stevanato Group Spa Dispositivo per collegare un serbatoio ad un percorso di fluido in un apparato di erogazione medicinali
EP4101482A1 (en) 2021-06-07 2022-12-14 Insulet Corporation Exercise safety prediction based on physiological conditions
US12514980B2 (en) 2021-06-30 2026-01-06 Insulet Corporation Adjustment of medicament delivery by a medicament delivery device based on menstrual cycle phase
US12521486B2 (en) 2021-07-16 2026-01-13 Insulet Corporation Method for modification of insulin delivery during pregnancy in automatic insulin delivery systems
WO2023049900A1 (en) 2021-09-27 2023-03-30 Insulet Corporation Techniques enabling adaptation of parameters in aid systems by user input
USD1007676S1 (en) 2021-11-16 2023-12-12 Regeneron Pharmaceuticals, Inc. Wearable autoinjector
US11439754B1 (en) 2021-12-01 2022-09-13 Insulet Corporation Optimizing embedded formulations for drug delivery
EP4243030A1 (en) 2022-03-09 2023-09-13 Insulet Corporation Adjusting medicament delivery parameters in an open loop medicament delivery mode
US20250388877A1 (en) 2022-07-07 2025-12-25 Suntory Holdings Limited Steviol glycoside biosynthesis mutant enzyme and use of same
KR20250044385A (ko) 2022-08-04 2025-03-31 인슐렛 코포레이션 이중 저장조 및 고정 유체 포트를 갖는 펌프 기구
IT202200024786A1 (it) 2022-12-01 2024-06-01 Nuova Ompi S R L Unipersonale Dispositivo di erogazione sottocutanea di un medicamento
EP4646726A1 (en) 2023-01-06 2025-11-12 Insulet Corporation Automatically or manually initiated meal bolus delivery with subsequent automatic safety constraint relaxation
WO2024256916A1 (en) * 2023-06-16 2024-12-19 Janssen Biotech, Inc. Drug delivery device
WO2025117518A1 (en) * 2023-11-30 2025-06-05 Sanofi Fluid barrier with breaking ram for large volume drug delivery device
US20260069764A1 (en) * 2024-09-06 2026-03-12 Sanofi-Aventis Deutschland Gmbh Method of operating a large-volume delivery device
US20260069763A1 (en) * 2024-09-06 2026-03-12 Sanofi-Aventis Deutschland Gmbh Method of assembling a large volume delivery device

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3336924A (en) * 1964-02-20 1967-08-22 Sarnoff Two compartment syringe package
US3419181A (en) * 1967-11-07 1968-12-31 Continental Can Co Score guard overcap for full open ends
US3986508A (en) 1973-08-22 1976-10-19 Abcor, Inc. Sterilizable, medical connector for blood processing
US4161949A (en) 1977-10-27 1979-07-24 Pennwalt Corporation Aseptic connector
US4457749A (en) 1982-04-19 1984-07-03 Baxter Travenol Laboratories, Inc. Shield for connectors
JP3702377B2 (ja) 1996-01-11 2005-10-05 株式会社大塚製薬工場 両頭針付き溶解液容器
JP3607464B2 (ja) 1997-07-17 2005-01-05 テルモ株式会社 薬液注入器具
US6022339A (en) 1998-09-15 2000-02-08 Baxter International Inc. Sliding reconstitution device for a diluent container
AU2002213484A1 (en) * 2000-10-20 2002-05-06 Baxter International Inc. Multi-dose container system
WO2006120253A2 (en) * 2005-05-13 2006-11-16 Novo Nordisk A/S Medical device adapted to detect disengagement of a transcutaneous device
US8057436B2 (en) * 2005-09-26 2011-11-15 Asante Solutions, Inc. Dispensing fluid from an infusion pump system
US7611502B2 (en) * 2005-10-20 2009-11-03 Covidien Ag Connector for enteral fluid delivery set
AU2009290976B2 (en) * 2008-09-10 2015-05-28 F. Hoffmann-La Roche Ag Delivery device for use with a therapeutic drug
CA2779793C (en) 2009-11-03 2014-04-08 F. Hoffmann-La Roche Ag Device for almost germ-free provision of a fluid medium
WO2011146166A1 (en) * 2010-05-20 2011-11-24 Becton Dickinson And Company Drug delivery device
ES2732080T3 (es) * 2011-02-09 2019-11-20 Becton Dickinson Co Dispositivo de infusión subcutánea
US9814832B2 (en) * 2011-09-02 2017-11-14 Unl Holdings Llc Drive mechanism for drug delivery pumps with integrated status indication
CA2845379C (en) 2011-09-02 2019-08-06 Unitract Syringe Pty Ltd Insertion mechanism for a drug delivery pump
BR112014004530A2 (pt) * 2011-09-02 2017-03-28 Unitract Syringe Pty Ltd mecanismo de acionamento para bombas de administração de fármaco com indicação de estado integrada
MX352613B (es) * 2011-09-13 2017-12-01 Unitract Syringe Pty Ltd Conexión estéril de vía de fluido para contenedores de fármacos para bombas de suministro de fármacos.
PL3045187T3 (pl) 2011-10-14 2019-09-30 Amgen Inc. Wstrzykiwacz i sposób montażu
WO2013188703A1 (en) * 2012-06-13 2013-12-19 Py Daniel C Device with penetrable septum and closure needle
JP6355169B2 (ja) 2012-08-29 2018-07-11 ユーエヌエル ホールディングス エルエルシーUNL Holdings LLC 薬剤送達ポンプ用制御送達駆動機構
DK3041529T3 (en) * 2013-09-05 2019-03-11 Sanofi Aventis Deutschland DEVICE FOR CANNEL INSTALLATION AND WITHDRAWAL WITH MANUALLY LOCKABLE, SPRING LOADED DRIVE MECHANISM
CA2931949C (en) * 2013-12-01 2020-01-14 Becton, Dickinson And Company Medicament device
JP6713467B2 (ja) 2014-09-29 2020-06-24 ユーエヌエル ホールディングス エルエルシーUNL Holdings LLC 薬剤送達ポンプの為の剛性針挿入機構
CN107635527B (zh) * 2015-03-10 2021-04-23 里珍纳龙药品有限公司 无菌刺穿系统和方法
JOP20170042B1 (ar) * 2016-02-12 2022-09-15 Amgen Inc وسيلة توصيل عقار، طريقة تصنيعه وطريقة استخدامه

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