MX385489B - Composicion oftalmica que comprende pvp-i. - Google Patents
Composicion oftalmica que comprende pvp-i.Info
- Publication number
- MX385489B MX385489B MX2018012311A MX2018012311A MX385489B MX 385489 B MX385489 B MX 385489B MX 2018012311 A MX2018012311 A MX 2018012311A MX 2018012311 A MX2018012311 A MX 2018012311A MX 385489 B MX385489 B MX 385489B
- Authority
- MX
- Mexico
- Prior art keywords
- ophthalmic composition
- oil phase
- pvp
- includes pvp
- composition
- Prior art date
Links
- CPKVUHPKYQGHMW-UHFFFAOYSA-N 1-ethenylpyrrolidin-2-one;molecular iodine Chemical compound II.C=CN1CCCC1=O CPKVUHPKYQGHMW-UHFFFAOYSA-N 0.000 title 1
- 239000012071 phase Substances 0.000 abstract 3
- FAAHNQAYWKTLFD-UHFFFAOYSA-N 1-butan-2-ylpyrrolidin-2-one Chemical compound CCC(C)N1CCCC1=O FAAHNQAYWKTLFD-UHFFFAOYSA-N 0.000 abstract 1
- 239000008346 aqueous phase Substances 0.000 abstract 1
- 229940057917 medium chain triglycerides Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
- A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
- A61K31/79—Polymers of vinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/18—Iodine; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
El objetivo de la presente invención es una composición oftálmica que comprende povidona yodada (PVP-l) a una concentración de entre un 0,2-1,0% (p/p), en la que dicha composición oftálmica tiene una fase acuosa y una fase oleosa, consistiendo dicha fase oleosa en triglicéridos de cadena media y constituyendo dicha fase oleosa menos de un 3% del peso total de dicha composición.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITUA2016A002425A ITUA20162425A1 (it) | 2016-04-08 | 2016-04-08 | Composizione oftalmica che comprende PVP-I |
| PCT/IB2017/050911 WO2017175075A1 (en) | 2016-04-08 | 2017-02-17 | Ophthalmic composition comprising pvp-i |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2018012311A MX2018012311A (es) | 2019-05-22 |
| MX385489B true MX385489B (es) | 2025-03-18 |
Family
ID=56555535
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018012311A MX385489B (es) | 2016-04-08 | 2017-02-17 | Composicion oftalmica que comprende pvp-i. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20200000714A1 (es) |
| EP (1) | EP3439631B1 (es) |
| CN (1) | CN108883064B (es) |
| AU (1) | AU2017247694B2 (es) |
| CA (1) | CA3019748C (es) |
| CL (1) | CL2018002861A1 (es) |
| ES (1) | ES2950498T3 (es) |
| IT (1) | ITUA20162425A1 (es) |
| MA (1) | MA44601A (es) |
| MX (1) | MX385489B (es) |
| PL (1) | PL3439631T3 (es) |
| PT (1) | PT3439631T (es) |
| RU (1) | RU2740910C2 (es) |
| WO (1) | WO2017175075A1 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108451903B (zh) * | 2018-07-05 | 2019-03-22 | 广东腾骏动物药业股份有限公司 | 一种聚维酮碘溶液及其制备方法 |
| CA3107304A1 (en) * | 2018-07-24 | 2020-01-30 | Carefusion 213, Llc | Ready-to-use, terminally sterile packaging for surgical antiseptic and method of use |
| US12472162B2 (en) * | 2018-07-24 | 2025-11-18 | Carefusion 213, Llc | Ready-to-use, terminally sterile packaging for surgical antiseptic and method of use |
| CN114502205B (zh) * | 2019-08-18 | 2024-08-06 | 艾威药业公司 | 含稀聚维酮碘制剂的稳定药品 |
| CN110559175A (zh) * | 2019-08-27 | 2019-12-13 | 陈文龙 | 一种结膜囊消毒溶液及其使用方法和装置 |
| EP4100063A1 (en) * | 2020-02-03 | 2022-12-14 | Medivis S.r.l. | Stable ophthalmic formulations based on low-concentration povidone iodide in plastic containers |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1989000044A1 (fr) * | 1987-07-07 | 1989-01-12 | Santen Pharmaceutical Co., Ltd. | Larme artificielle |
| NL9002049A (nl) * | 1990-09-18 | 1992-04-16 | Dagra Pharma Bv | Oogheelkundig preparaat dat een povidon-joodoplossing bevat. |
| US5863556A (en) * | 1993-08-20 | 1999-01-26 | Euro-Celtique, S.A. | Preparations for the external application of antiseptic agents and/or agents promoting the healing of wounds |
| GB0413954D0 (en) * | 2004-06-22 | 2004-07-28 | Altunkaya Ali | Compositions for topical treatment |
| US7767217B2 (en) * | 2006-03-14 | 2010-08-03 | Foresight Biotherapeutics | Ophthalmic compositions comprising povidone-iodine |
| JP2011505409A (ja) * | 2007-12-04 | 2011-02-24 | ノバガリ ファーマ エスエー | パルミチン酸デキサメタゾンのようなコルチコステロイドプロドラッグを含有する眼障害の治療用の組成物 |
| EP2278953B1 (en) * | 2008-05-28 | 2016-05-04 | Alcon Research, Ltd | Self-preserved emulsions |
| EP3777536A1 (en) * | 2008-06-12 | 2021-02-17 | Takeda Pharmaceutical Company Limited | Povidone iodine, a novel alternative preservative for ophthalmic compositions |
| IT1404931B1 (it) * | 2010-06-11 | 2013-12-09 | Medivis S R L | Composizioni oftalmiche per la somministrazione di principi attivi liposolubili . |
| CN102429862B (zh) * | 2011-11-29 | 2013-05-01 | 江苏德达医药科技有限公司 | 一种聚维酮碘眼用缓释滴眼液 |
-
2016
- 2016-04-08 IT ITUA2016A002425A patent/ITUA20162425A1/it unknown
-
2017
- 2017-02-17 WO PCT/IB2017/050911 patent/WO2017175075A1/en not_active Ceased
- 2017-02-17 MX MX2018012311A patent/MX385489B/es unknown
- 2017-02-17 MA MA044601A patent/MA44601A/fr unknown
- 2017-02-17 RU RU2018139074A patent/RU2740910C2/ru active
- 2017-02-17 CN CN201780022544.XA patent/CN108883064B/zh active Active
- 2017-02-17 PT PT177142817T patent/PT3439631T/pt unknown
- 2017-02-17 EP EP17714281.7A patent/EP3439631B1/en active Active
- 2017-02-17 AU AU2017247694A patent/AU2017247694B2/en active Active
- 2017-02-17 PL PL17714281.7T patent/PL3439631T3/pl unknown
- 2017-02-17 ES ES17714281T patent/ES2950498T3/es active Active
- 2017-02-17 CA CA3019748A patent/CA3019748C/en active Active
- 2017-02-17 US US16/092,173 patent/US20200000714A1/en active Pending
-
2018
- 2018-10-08 CL CL2018002861A patent/CL2018002861A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2950498T3 (es) | 2023-10-10 |
| RU2740910C2 (ru) | 2021-01-21 |
| BR112018070734A2 (pt) | 2019-02-05 |
| EP3439631A1 (en) | 2019-02-13 |
| US20200000714A1 (en) | 2020-01-02 |
| AU2017247694B2 (en) | 2022-04-21 |
| WO2017175075A1 (en) | 2017-10-12 |
| RU2018139074A3 (es) | 2020-06-30 |
| CN108883064A (zh) | 2018-11-23 |
| EP3439631B1 (en) | 2023-05-10 |
| CA3019748C (en) | 2024-01-09 |
| AU2017247694A1 (en) | 2018-10-25 |
| MA44601A (fr) | 2019-02-13 |
| CN108883064B (zh) | 2022-09-16 |
| PT3439631T (pt) | 2023-07-28 |
| RU2018139074A (ru) | 2020-05-12 |
| CA3019748A1 (en) | 2017-10-12 |
| CL2018002861A1 (es) | 2019-02-22 |
| PL3439631T3 (pl) | 2023-09-04 |
| MX2018012311A (es) | 2019-05-22 |
| ITUA20162425A1 (it) | 2017-10-08 |
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