CL2018002861A1 - Composición oftálmica que comprende pvp-i. - Google Patents

Composición oftálmica que comprende pvp-i.

Info

Publication number
CL2018002861A1
CL2018002861A1 CL2018002861A CL2018002861A CL2018002861A1 CL 2018002861 A1 CL2018002861 A1 CL 2018002861A1 CL 2018002861 A CL2018002861 A CL 2018002861A CL 2018002861 A CL2018002861 A CL 2018002861A CL 2018002861 A1 CL2018002861 A1 CL 2018002861A1
Authority
CL
Chile
Prior art keywords
pvp
phase
composition
ophthalmic composition
oleous
Prior art date
Application number
CL2018002861A
Other languages
English (en)
Inventor
Danilo Aleo
Melina Cro
Sergio Mangiafico
Barbara MELILLI
Maria Grazia Saita
Original Assignee
Medivis S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medivis S R L filed Critical Medivis S R L
Publication of CL2018002861A1 publication Critical patent/CL2018002861A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A61K31/79—Polymers of vinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/18—Iodine; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

EL OBJETIVO DE LA PRESENTE INVENCIÓN ES UNA COMPOSICIÓN OFTÁLMICA QUE COMPRENDE POVIDONA YODADA (PVP-I) A UNA CONCENTRACIÓN DE ENTRE UN 0,2-1,0% (P/P), EN LA QUE DICHA COMPOSICIÓN OFTÁLMICA TIENE UNA FASE ACUOSA Y UNA FASE OLEOSA, CONSISTIENDO DICHA FASE OLEOSA EN TRIGLICÉRIDOS DE CADENA MEDIA Y CONSTITUYENDO DICHA FASE OLEOSA MENOS DE UN 3% DEL PESO TOTAL DE DICHA COMPOSICIÓN.
CL2018002861A 2016-04-08 2018-10-08 Composición oftálmica que comprende pvp-i. CL2018002861A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITUA2016A002425A ITUA20162425A1 (it) 2016-04-08 2016-04-08 Composizione oftalmica che comprende PVP-I

Publications (1)

Publication Number Publication Date
CL2018002861A1 true CL2018002861A1 (es) 2019-02-22

Family

ID=56555535

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2018002861A CL2018002861A1 (es) 2016-04-08 2018-10-08 Composición oftálmica que comprende pvp-i.

Country Status (14)

Country Link
US (1) US20200000714A1 (es)
EP (1) EP3439631B1 (es)
CN (1) CN108883064B (es)
AU (1) AU2017247694B2 (es)
CA (1) CA3019748C (es)
CL (1) CL2018002861A1 (es)
ES (1) ES2950498T3 (es)
IT (1) ITUA20162425A1 (es)
MA (1) MA44601A (es)
MX (1) MX2018012311A (es)
PL (1) PL3439631T3 (es)
PT (1) PT3439631T (es)
RU (1) RU2740910C2 (es)
WO (1) WO2017175075A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108451903B (zh) * 2018-07-05 2019-03-22 广东腾骏动物药业股份有限公司 一种聚维酮碘溶液及其制备方法
EP4013461A4 (en) * 2019-08-18 2023-08-23 IVIEW Therapeutics, Inc. STABLE PHARMACEUTICAL ARTICLES CONTAINING DILUTE FORMULATIONS OF POVIDONE-IODINE
CN110559175A (zh) * 2019-08-27 2019-12-13 陈文龙 一种结膜囊消毒溶液及其使用方法和装置
EP4100063A1 (en) * 2020-02-03 2022-12-14 Medivis S.r.l. Stable ophthalmic formulations based on low-concentration povidone iodide in plastic containers

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL9002049A (nl) * 1990-09-18 1992-04-16 Dagra Pharma Bv Oogheelkundig preparaat dat een povidon-joodoplossing bevat.
US5863556A (en) * 1993-08-20 1999-01-26 Euro-Celtique, S.A. Preparations for the external application of antiseptic agents and/or agents promoting the healing of wounds
GB0413954D0 (en) * 2004-06-22 2004-07-28 Altunkaya Ali Compositions for topical treatment
US7767217B2 (en) * 2006-03-14 2010-08-03 Foresight Biotherapeutics Ophthalmic compositions comprising povidone-iodine
EP2229174A1 (en) * 2007-12-04 2010-09-22 Novagali Pharma S.A. Compositions comprising corticosteroid prodrug such as dexamethasone palmitate for the treatment of eye disorders
JP2011521957A (ja) * 2008-05-28 2011-07-28 アルコン リサーチ， リミテッド 自己防腐エマルジョン
NZ603346A (en) * 2008-06-12 2014-05-30 Foresight Biotherapeutics Inc Povidone iodine, a novel alternative preservative for ophthalmic compositions
IT1404931B1 (it) * 2010-06-11 2013-12-09 Medivis S R L Composizioni oftalmiche per la somministrazione di principi attivi liposolubili .
CN102429862B (zh) * 2011-11-29 2013-05-01 江苏德达医药科技有限公司 一种聚维酮碘眼用缓释滴眼液

Also Published As

Publication number Publication date
EP3439631B1 (en) 2023-05-10
EP3439631A1 (en) 2019-02-13
BR112018070734A2 (pt) 2019-02-05
MX2018012311A (es) 2019-05-22
CA3019748A1 (en) 2017-10-12
RU2018139074A (ru) 2020-05-12
CN108883064A (zh) 2018-11-23
ITUA20162425A1 (it) 2017-10-08
RU2018139074A3 (es) 2020-06-30
MA44601A (fr) 2019-02-13
US20200000714A1 (en) 2020-01-02
PT3439631T (pt) 2023-07-28
AU2017247694B2 (en) 2022-04-21
CN108883064B (zh) 2022-09-16
RU2740910C2 (ru) 2021-01-21
WO2017175075A1 (en) 2017-10-12
AU2017247694A1 (en) 2018-10-25
ES2950498T3 (es) 2023-10-10
PL3439631T3 (pl) 2023-09-04
CA3019748C (en) 2024-01-09

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