MX384751B - Tratamiento del cáncer con una combinación de plinabulina y taxano. - Google Patents
Tratamiento del cáncer con una combinación de plinabulina y taxano.Info
- Publication number
- MX384751B MX384751B MX2016004441A MX2016004441A MX384751B MX 384751 B MX384751 B MX 384751B MX 2016004441 A MX2016004441 A MX 2016004441A MX 2016004441 A MX2016004441 A MX 2016004441A MX 384751 B MX384751 B MX 384751B
- Authority
- MX
- Mexico
- Prior art keywords
- combination
- taxane compound
- taxane
- plinabulin
- cancer treatment
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 5
- 229940123237 Taxane Drugs 0.000 title abstract 5
- 201000011510 cancer Diseases 0.000 title abstract 4
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 title 1
- -1 taxane compound Chemical class 0.000 abstract 4
- UNRCMCRRFYFGFX-TYPNBTCFSA-N plinabulin Chemical compound N1C=NC(\C=C/2C(NC(=C\C=3C=CC=CC=3)/C(=O)N\2)=O)=C1C(C)(C)C UNRCMCRRFYFGFX-TYPNBTCFSA-N 0.000 abstract 3
- 229950011498 plinabulin Drugs 0.000 abstract 3
- 230000003247 decreasing effect Effects 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 102000004269 Granulocyte Colony-Stimulating Factor Human genes 0.000 abstract 1
- 108010017080 Granulocyte Colony-Stimulating Factor Proteins 0.000 abstract 1
- ZDZOTLJHXYCWBA-VCVYQWHSSA-N N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol Chemical compound O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C=4C=CC=CC=4)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 ZDZOTLJHXYCWBA-VCVYQWHSSA-N 0.000 abstract 1
- 238000010171 animal model Methods 0.000 abstract 1
- 108010054981 dehydrophenylahistin Proteins 0.000 abstract 1
- 229960003668 docetaxel Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 208000004235 neutropenia Diseases 0.000 abstract 1
- 208000002154 non-small cell lung carcinoma Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CN2013/085075 WO2015051543A1 (en) | 2013-10-11 | 2013-10-11 | Cancer treatment with combination of plinabulin and taxane |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2016004441A MX2016004441A (es) | 2016-10-28 |
| MX384751B true MX384751B (es) | 2025-03-14 |
Family
ID=52812462
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2016004441A MX384751B (es) | 2013-10-11 | 2013-10-11 | Tratamiento del cáncer con una combinación de plinabulina y taxano. |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US10596169B2 (enExample) |
| EP (1) | EP3076972B1 (enExample) |
| JP (1) | JP6411523B2 (enExample) |
| KR (1) | KR102225371B1 (enExample) |
| CN (1) | CN105705148B (enExample) |
| AU (1) | AU2013402794B2 (enExample) |
| BR (1) | BR112016007946A2 (enExample) |
| CA (1) | CA2926771C (enExample) |
| DK (1) | DK3076972T3 (enExample) |
| ES (1) | ES2902665T3 (enExample) |
| IL (1) | IL244984B (enExample) |
| MX (1) | MX384751B (enExample) |
| MY (1) | MY185650A (enExample) |
| NZ (1) | NZ719049A (enExample) |
| RU (1) | RU2662298C2 (enExample) |
| SG (1) | SG11201602637QA (enExample) |
| WO (1) | WO2015051543A1 (enExample) |
| ZA (1) | ZA201602380B (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20180028531A1 (en) * | 2015-02-12 | 2018-02-01 | BeyondSpring Phamaceuticals, Inc. | Use of plinabulin in combination with immune checkpoint inhibitors |
| US10238650B2 (en) | 2015-03-06 | 2019-03-26 | Beyondspring Pharmaceuticals, Inc. | Method of treating cancer associated with a RAS mutation |
| SG11201707128TA (en) | 2015-03-06 | 2017-09-28 | Beyondspring Pharmaceuticals Inc | Method of treating a brain tumor |
| ES2910035T3 (es) | 2015-07-13 | 2022-05-11 | Beyondspring Pharmaceuticals Inc | Composiciones de plinabulina |
| BR112018016054A2 (pt) | 2016-02-08 | 2019-02-12 | Beyondspring Pharmaceuticals, Inc. | composições farmacêuticas e/ou métodos para tratar câncer e/ou para romper vasculatura de tumor associada ao câncer em indivíduo |
| MX389200B (es) * | 2016-06-06 | 2025-03-20 | Beyondspring Pharmaceuticals Inc | Composición y método para reducir la neutropenia. |
| CN110431135A (zh) | 2017-01-06 | 2019-11-08 | 大连万春布林医药有限公司 | 微管蛋白结合化合物及其治疗用途 |
| KR20190109479A (ko) * | 2017-02-01 | 2019-09-25 | 비욘드스프링 파마수티컬스, 인코포레이티드. | 호중구감소증의 감소 방법 |
| EP3595653B1 (en) * | 2017-03-13 | 2023-03-08 | Beyondspring Pharmaceuticals, Inc. | Compositions of plinabulin and use thereof |
| CN109498627B (zh) * | 2017-09-15 | 2021-06-04 | 深圳华大海洋科技有限公司 | 一种治疗肿瘤的药物组合物及其应用 |
| WO2019147615A1 (en) * | 2018-01-24 | 2019-08-01 | Beyondspring Pharmaceuticals, Inc. | Composition and method for reducing thrombocytopenia via the administration of plinabulin |
| KR20200116477A (ko) * | 2018-02-01 | 2020-10-12 | 비욘드스프링 파마수티컬스, 인코포레이티드. | 플리나불린 및 g-csf 제제의 투여를 통해 화학요법-유도된 호중구감소증을 감소시키기 위한 조성물 및 방법 |
| CN108524442B (zh) * | 2018-06-05 | 2022-01-28 | 深圳海王医药科技研究院有限公司 | 一种抗肿瘤药物的注射剂及其制备方法 |
| JP2018199726A (ja) * | 2018-09-26 | 2018-12-20 | ビヨンドスプリング インコーポレイテッド | プリナブリン及びタキサンの組合せがん治療 |
| US20230035763A1 (en) * | 2018-11-14 | 2023-02-02 | BeyondSpring Pharnaceuticals, Inc. | Methods of treating cancer using tubulin binding agents |
| CN110507653B (zh) * | 2019-08-02 | 2022-12-02 | 北京赛而生物药业有限公司 | 多潘立酮及其与紫杉醇联用在制备治疗癌症的药物中的应用 |
| EP4045046A4 (en) * | 2019-10-15 | 2024-01-10 | Beyondspring Pharmaceuticals Inc. | Methods and compositions for treating iron disorders |
| JP2024513505A (ja) * | 2021-04-09 | 2024-03-25 | ビヨンドスプリング ファーマシューティカルズ，インコーポレイテッド | 腫瘍を治療するための組成物及び方法 |
| CN113456643B (zh) * | 2021-08-11 | 2022-04-01 | 遵义医科大学 | 一种含普那布林的药物组合及其应用 |
| CN117860672A (zh) * | 2022-10-11 | 2024-04-12 | 大连万春布林医药有限公司 | 一种普那布林胶束组合物及其制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7141603B2 (en) | 1999-02-19 | 2006-11-28 | The Regents Of The University California | Antitumor agents |
| US7012100B1 (en) | 2002-06-04 | 2006-03-14 | Avolix Pharmaceuticals, Inc. | Cell migration inhibiting compositions and methods and compositions for treating cancer |
| US7919497B2 (en) | 2002-08-02 | 2011-04-05 | Nereus Pharmaceuticals, Inc. | Analogs of dehydrophenylahistins and their therapeutic use |
| AU2003302721B2 (en) | 2002-08-02 | 2009-10-08 | Beyondspring Pharmaceuticals, Inc. | Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof |
| BRPI0506655A (pt) * | 2004-02-04 | 2007-05-08 | Nereus Pharmaceuticals Inc | dehidrofenilahistinas e seus análogos, e sìntese de dehidrofenilahistinas e seus análogos |
| GB0907551D0 (en) * | 2009-05-01 | 2009-06-10 | Univ Dundee | Treatment or prophylaxis of proliferative conditions |
| AU2014244083B2 (en) | 2013-03-13 | 2018-09-27 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods for modulating chemotherapeutic cytotoxicity |
-
2013
- 2013-10-11 EP EP13895342.7A patent/EP3076972B1/en active Active
- 2013-10-11 MX MX2016004441A patent/MX384751B/es unknown
- 2013-10-11 RU RU2016112608A patent/RU2662298C2/ru active
- 2013-10-11 SG SG11201602637QA patent/SG11201602637QA/en unknown
- 2013-10-11 BR BR112016007946A patent/BR112016007946A2/pt not_active Application Discontinuation
- 2013-10-11 US US15/028,376 patent/US10596169B2/en active Active
- 2013-10-11 KR KR1020167012255A patent/KR102225371B1/ko active Active
- 2013-10-11 CN CN201380080185.5A patent/CN105705148B/zh active Active
- 2013-10-11 ES ES13895342T patent/ES2902665T3/es active Active
- 2013-10-11 WO PCT/CN2013/085075 patent/WO2015051543A1/en not_active Ceased
- 2013-10-11 NZ NZ719049A patent/NZ719049A/en unknown
- 2013-10-11 JP JP2016547208A patent/JP6411523B2/ja active Active
- 2013-10-11 AU AU2013402794A patent/AU2013402794B2/en active Active
- 2013-10-11 MY MYPI2016000620A patent/MY185650A/en unknown
- 2013-10-11 CA CA2926771A patent/CA2926771C/en active Active
- 2013-10-11 DK DK13895342.7T patent/DK3076972T3/da active
-
2016
- 2016-04-07 IL IL244984A patent/IL244984B/en unknown
- 2016-04-08 ZA ZA2016/02380A patent/ZA201602380B/en unknown
-
2020
- 2020-03-17 US US16/821,348 patent/US20200281921A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| RU2662298C2 (ru) | 2018-07-25 |
| MY185650A (en) | 2021-05-27 |
| JP6411523B2 (ja) | 2018-10-24 |
| CA2926771C (en) | 2022-07-05 |
| EP3076972A4 (en) | 2017-12-20 |
| JP2016536352A (ja) | 2016-11-24 |
| EP3076972A1 (en) | 2016-10-12 |
| WO2015051543A1 (en) | 2015-04-16 |
| AU2013402794A1 (en) | 2016-05-12 |
| US20160250209A1 (en) | 2016-09-01 |
| WO2015051543A8 (en) | 2016-04-21 |
| IL244984A0 (en) | 2016-05-31 |
| NZ719049A (en) | 2020-06-26 |
| RU2016112608A (ru) | 2017-11-16 |
| DK3076972T3 (da) | 2022-01-03 |
| CN105705148B (zh) | 2021-03-23 |
| ES2902665T3 (es) | 2022-03-29 |
| IL244984B (en) | 2022-05-01 |
| KR102225371B1 (ko) | 2021-03-10 |
| EP3076972B1 (en) | 2021-10-06 |
| CN105705148A (zh) | 2016-06-22 |
| SG11201602637QA (en) | 2016-05-30 |
| US20200281921A1 (en) | 2020-09-10 |
| KR20160078987A (ko) | 2016-07-05 |
| ZA201602380B (en) | 2022-05-25 |
| MX2016004441A (es) | 2016-10-28 |
| US10596169B2 (en) | 2020-03-24 |
| BR112016007946A2 (pt) | 2017-09-12 |
| CA2926771A1 (en) | 2015-04-16 |
| AU2013402794B2 (en) | 2020-02-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX384751B (es) | Tratamiento del cáncer con una combinación de plinabulina y taxano. | |
| PH12019501197A1 (en) | Therapeutically active compounds and their methods of use | |
| MA40437A (fr) | Méthodes de traitement du cancer faisant appel à des inhibiteurs de tigit et à des agents anticancéreux | |
| MX2015011783A (es) | Metodos para tratar tumores solidos pediatricos. | |
| MX377729B (es) | Métodos para tratamiento del melanoma. | |
| MX2017007321A (es) | Terapias de combinacion. | |
| PH12016500164B1 (en) | Therapeutically active compounds and their methods of use | |
| PH12017550063A1 (en) | Combination therapies for treating cancers | |
| WO2013177187A3 (en) | Synergistic tumor treatment with extended-pk il-2 and therapeutic agents | |
| EA201491330A1 (ru) | Терапевтически активные соединения и способы их использования | |
| MX370567B (es) | Tratamiento de mielosupresion. | |
| MX2015014773A (es) | Tratamientos anti-cancer con anticuerpos anti-egfr que tienen una fucosilacion baja. | |
| MX2016000131A (es) | Nanoparticulas polimericas de docetaxel para el tratamiento de cancer. | |
| MX2015010791A (es) | Metodos para tratar el cancer y prevenir la resistencia a farmacos. | |
| EA201591925A1 (ru) | Терапевтические композиции и их применение | |
| BR112017018964A2 (pt) | uso de plinabulin e métodos para tratar tumor cerebral | |
| CA2908742C (en) | Combination therapy comprising a tor kinase inhibitor and a cytidine analog for treating cancer | |
| ZA201708686B (en) | Nanoparticles for use as a therapeutic vaccine | |
| MX380835B (es) | Terapia de combinación pac-1. | |
| EA201690445A1 (ru) | Лечение рака | |
| PH12016501101A1 (en) | Veliparib in combination with carboplatin for the treatment of triple negative breast cancer | |
| MX2017013666A (es) | Terapia de combinacion de agente anti-fuctactico y agente de inmunoterapia y composiciones para el tratamiento de cancer. | |
| MX2017013668A (es) | Terapia de combinacion de agente anti-fuctactico y agente anti-cancer y composiciones para el tratamiento de cancer. | |
| MX2021001081A (es) | Terapia de combinacion para el tratamiento del cancer. | |
| HK1229712A1 (en) | Cancer treatment with combination of plinabulin and taxane |