MX384192B - Composiciones farmaceuticas que comprenden un antagonista de il-4r para usarse en el tratamiento del asma. - Google Patents

Composiciones farmaceuticas que comprenden un antagonista de il-4r para usarse en el tratamiento del asma.

Info

Publication number
MX384192B
MX384192B MX2016010854A MX2016010854A MX384192B MX 384192 B MX384192 B MX 384192B MX 2016010854 A MX2016010854 A MX 2016010854A MX 2016010854 A MX2016010854 A MX 2016010854A MX 384192 B MX384192 B MX 384192B
Authority
MX
Mexico
Prior art keywords
antagonist
treating
methods
administering
preventing asthma
Prior art date
Application number
MX2016010854A
Other languages
English (en)
Spanish (es)
Other versions
MX2016010854A (es
Inventor
Franck Skobieranda
Gianluca Pirozzi
Neil Graham
Steven P Weinstein
Yongtao Li
Original Assignee
Sanofi Biotechnology
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51570453&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX384192(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Biotechnology, Regeneron Pharma filed Critical Sanofi Biotechnology
Publication of MX2016010854A publication Critical patent/MX2016010854A/es
Publication of MX384192B publication Critical patent/MX384192B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MX2016010854A 2014-02-21 2015-02-20 Composiciones farmaceuticas que comprenden un antagonista de il-4r para usarse en el tratamiento del asma. MX384192B (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201461943019P 2014-02-21 2014-02-21
EP14306413 2014-09-15
US201462077669P 2014-11-10 2014-11-10
PCT/US2015/016852 WO2015127229A1 (en) 2014-02-21 2015-02-20 Methods for treating or preventing asthma by administering an il-4r antagonist

Publications (2)

Publication Number Publication Date
MX2016010854A MX2016010854A (es) 2017-01-05
MX384192B true MX384192B (es) 2025-03-14

Family

ID=51570453

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2016010854A MX384192B (es) 2014-02-21 2015-02-20 Composiciones farmaceuticas que comprenden un antagonista de il-4r para usarse en el tratamiento del asma.
MX2021008113A MX2021008113A (es) 2014-02-21 2016-08-19 Composiciones farmaceuticas que comprenden un antagonista de il-4r para usarse en el tratamiento del asma.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2021008113A MX2021008113A (es) 2014-02-21 2016-08-19 Composiciones farmaceuticas que comprenden un antagonista de il-4r para usarse en el tratamiento del asma.

Country Status (15)

Country Link
US (3) US10137193B2 (enExample)
EP (3) EP3973987B1 (enExample)
JP (3) JP6673840B2 (enExample)
KR (4) KR102368450B1 (enExample)
CN (1) CN106232140A (enExample)
AU (3) AU2015218808B2 (enExample)
CA (1) CA2940295A1 (enExample)
ES (2) ES2977332T3 (enExample)
HU (1) HUE065844T2 (enExample)
IL (1) IL315136A (enExample)
MX (2) MX384192B (enExample)
PL (2) PL3973987T3 (enExample)
PT (2) PT3107575T (enExample)
RU (1) RU2713406C2 (enExample)
WO (1) WO2015127229A1 (enExample)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7608693B2 (en) * 2006-10-02 2009-10-27 Regeneron Pharmaceuticals, Inc. High affinity human antibodies to human IL-4 receptor
TWI656880B (zh) 2012-08-21 2019-04-21 法商賽諾菲生物技術公司 投與ｉｌ－４ｒ拮抗劑以治療或預防氣喘之方法
HUE039387T2 (hu) 2012-09-07 2018-12-28 Regeneron Pharma Atópiás dermatitisz kezelési módszerei egy IL-4R antagonista adagolásával
TWI755763B (zh) * 2013-06-04 2022-02-21 美商再生元醫藥公司 藉由投與il-4r抑制劑以治療過敏及增強過敏原-特異之免疫療法的方法
SI3010539T1 (sl) * 2013-06-21 2019-11-29 Regeneron Pharma Postopki za zdravljenje nazalne polipoze z administriranjem antagonista IL-4R
TWI634900B (zh) 2013-07-11 2018-09-11 再生元醫藥公司 藉由投與ｉｌ－４ｒ抑制劑治療嗜酸性食道炎的方法
CA2918035C (en) 2013-07-12 2023-01-03 Knopp Biosciences Llc Use of dexpramipexole in the treatment of disorders associated with elevated levels of eosinophils and/or basophils
IL315136A (en) 2014-02-21 2024-10-01 Sanofi Biotechnology Methods for treating or preventing asthma by administering an il-4rantagonist
AU2015222951B2 (en) 2014-02-28 2020-06-11 Regeneron Pharmaceuticals, Inc. Methods for treating skin infection by administering an IL-4R antagonist
WO2016077675A1 (en) 2014-11-14 2016-05-19 Sanofi Biotechnology Methods for treating chronic sinusitis with nasal polyps by administering an il-4r antagonist
US20180056018A1 (en) * 2016-08-31 2018-03-01 Cephalon, Inc. Inhalation Systems, Devices and Methods
CN109789196B (zh) 2016-09-01 2024-03-19 瑞泽恩制药公司 用于通过施用il-4r拮抗剂来预防或治疗变态反应的方法
KR20230006049A (ko) 2016-09-22 2023-01-10 리제너론 파아마슈티컬스, 인크. Il-4r 저해제 투여에 의한 중증 아토피 피부염의 치료 방법
TWI784988B (zh) * 2016-12-01 2022-12-01 美商再生元醫藥公司 治療發炎症狀的方法
CA3059350A1 (en) * 2017-04-13 2018-10-18 Regeneron Pharmaceuticals, Inc. Treatment and inhibition of inflammatory lung diseases in patients having risk alleles in the genes encoding il33 and il1rl1
US11154621B2 (en) 2017-06-27 2021-10-26 Ohio State Innovation Foundation Liponucleotide-based therapy for COPD
US11850283B2 (en) 2017-06-27 2023-12-26 Ohio State Innovation Foundation Liponucleotide-based therapy for asthma
WO2019028367A1 (en) 2017-08-04 2019-02-07 Regeneron Pharmaceuticals, Inc. METHODS OF TREATING ESOPHAGITIS WITH ACTIVE EOSINOPHILES
PT3515465T (pt) 2017-08-18 2024-03-04 Regeneron Pharma Métodos para o tratamento de uma dermatite atópica grave mediante a administração de um inibidor de il-4r
ES2969049T3 (es) 2017-10-30 2024-05-16 Sanofi Biotechnology Antagonista de IL-4R para uso en un método para tratar o prevenir el asma
SG11202009371WA (en) 2018-05-13 2020-10-29 Regeneron Pharma Methods for treating atopic dermatitis by administering an il-4r inhibitor
TWI838388B (zh) 2018-07-10 2024-04-11 美商雷傑納榮製藥公司 修飾結合分子以最小化已存在的交互作用
CN110872349A (zh) * 2018-09-04 2020-03-10 三生国健药业（上海）股份有限公司 结合人il-4r的抗体、其制备方法和用途
CN110746507B (zh) 2018-12-25 2020-06-26 江苏荃信生物医药有限公司 抗人白介素4受体α单克隆抗体及其应用
WO2020135710A1 (zh) * 2018-12-27 2020-07-02 中山康方生物医药有限公司 抗人il-4ra的抗体及其用途
CN121102493A (zh) 2019-03-21 2025-12-12 瑞泽恩制药公司 用于治疗过敏症的il-4/il-13途径抑制剂和浆细胞消融的组合
MX2021013427A (es) * 2019-05-01 2022-01-31 Sanofi Biotechnology Metodos para tratar o prevenir el asma mediante la administracion un antagonista de il-33.
CN115175700A (zh) * 2019-07-16 2022-10-11 赛诺菲生物技术公司 用于通过施用il-4r拮抗剂治疗或预防哮喘的方法
SG11202113312VA (en) 2019-08-05 2021-12-30 Regeneron Pharma Methods for treating allergy and enhancing allergen-specific immunotherapy by administering an il-4r antagonist
EP4010373A1 (en) 2019-08-05 2022-06-15 Regeneron Pharmaceuticals, Inc. Methods for treating atopic dermatitis by administering an il-4r antagonist
MX2022006992A (es) 2019-12-09 2022-07-13 Sanofi Biotechnology Metodos para tratar los trastornos relacionados con il-4/il-13 identificados digitalmente.
EP3992974A1 (en) 2020-11-02 2022-05-04 Sanofi Biotechnology Methods for treating digitally-identified il-4/il-13 related disorders
CN113797331A (zh) * 2020-06-16 2021-12-17 三生国健药业（上海）股份有限公司 一种稳定的抗IL-4Rα单克隆抗体液体制剂
AU2021322255A1 (en) * 2020-08-05 2023-02-23 Areteia Therapeutics, Inc. Use of dexpramipexole for the treatment of moderate to severe asthma
CA3194111A1 (en) * 2020-10-05 2022-04-14 Christine XU Methods for treating asthma in pediatric subjects by administering an il-4r antagonist
WO2023025217A1 (zh) * 2021-08-26 2023-03-02 正大天晴药业集团股份有限公司 抗il4r抗体的药物组合物及其用途
CN117368487A (zh) * 2023-09-28 2024-01-09 首都医科大学附属北京同仁医院 一种利用局部IgE预测或评估奥马珠单抗在治疗复发性鼻息肉中疗效的方法和应用
US20250230251A1 (en) 2023-12-20 2025-07-17 Bristol-Myers Squibb Company Antibodies targeting il-18 receptor beta (il-18rb) and related methods

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8808015D0 (en) 1988-04-06 1988-05-05 Ritter M A Chemical compounds
AU643427B2 (en) 1988-10-31 1993-11-18 Immunex Corporation Interleukin-4 receptors
US5714146A (en) 1992-08-26 1998-02-03 Board Of Regents Of The University Of Washington IL-4 bone therapy
EP0604693A1 (en) 1992-12-29 1994-07-06 Schering-Plough Monoclonal antibodies against the human interleukin-4 receptor and hybridomas producing the same
US6927044B2 (en) 1998-09-25 2005-08-09 Regeneron Pharmaceuticals, Inc. IL-1 receptor based cytokine traps
WO2001092340A2 (en) 2000-05-26 2001-12-06 Immunex Corporation Use of interleukin-4 antagonists and compositions thereof
US7879328B2 (en) 2000-06-16 2011-02-01 Human Genome Sciences, Inc. Antibodies that immunospecifically bind to B lymphocyte stimulator
US6596541B2 (en) 2000-10-31 2003-07-22 Regeneron Pharmaceuticals, Inc. Methods of modifying eukaryotic cells
US8178098B2 (en) 2001-04-03 2012-05-15 National Jewish Health Method to inhibit airway hyperresponsiveness using aerosolized T cell receptor antibodies
CA2543982C (en) 2003-11-07 2013-01-08 Immunex Corporation Antibodies that bind interleukin-4 receptor
AU2004309373A1 (en) 2003-12-22 2005-07-14 Amgen Inc. Methods for identifying functional antibodies
DE602005006758D1 (de) 2004-02-27 2008-06-26 Regeneron Pharma Il-4/il-13-spezifische polypetide und deren therapeutische verwendung
US20090098142A1 (en) 2004-06-09 2009-04-16 Kasaian Marion T Methods and compositions for treating and monitoring treatment of IL-13-associated disorders
TWI306862B (en) 2005-01-03 2009-03-01 Hoffmann La Roche Antibodies against il-13 receptor alpha 1 and uses thereof
TW200804593A (en) * 2006-01-24 2008-01-16 Domantis Ltd Fusion proteins that contain natural junctions
JP5307708B2 (ja) 2006-06-02 2013-10-02 リジェネロン・ファーマシューティカルズ・インコーポレイテッド ヒトｉｌ−６受容体に対する高親和性抗体
CA2664343C (en) 2006-10-02 2016-04-26 Regeneron Pharmaceuticals, Inc. High affinity human antibodies to human il-4 receptor
US7608693B2 (en) 2006-10-02 2009-10-27 Regeneron Pharmaceuticals, Inc. High affinity human antibodies to human IL-4 receptor
EP2022507A1 (en) 2007-08-07 2009-02-11 Universität Hamburg Antibody compositions specific for lgE, lgG4 and lgA epitopes as tools for the design of hypoallergenic molecules for specific immunotherapy
EP2050764A1 (en) * 2007-10-15 2009-04-22 sanofi-aventis Novel polyvalent bispecific antibody format and uses thereof
WO2009081201A2 (en) * 2007-12-21 2009-07-02 Medimmune Limited BINDING MEMBERS FOR INTERLEUKIN-4 RECEPTOR ALPHA (IL-4Rα) - 173
WO2010065557A2 (en) 2008-12-01 2010-06-10 Cincinnati Children's Hospital Medical Center Methods of determining efficacy of glucocorticoid treatment of eosinophilic esophagitis
WO2010120511A2 (en) 2009-03-31 2010-10-21 Altair Therapeutics, Inc. Method of treating respiratory disorders
WO2011156000A2 (en) * 2010-06-07 2011-12-15 Aerovance, Inc. Use of il-4/il-13 antagonists to treat eosinophilic disorders
SG189220A1 (en) 2010-10-06 2013-05-31 Regeneron Pharma Stabilized formulations containing anti-interleukin-4 receptor (il-4r) antibodies
ES2645368T3 (es) * 2010-10-15 2017-12-05 Medimmune Limited Terapias para mejorar la función pulmonar
US20130052190A1 (en) 2011-02-22 2013-02-28 Oxagen Limited CRTH2 Antagonists for Treatment of Eosinophilic Diseases and Conditions
CA2853858A1 (en) * 2011-11-01 2013-05-10 Medimmune, Llc Methods for reducing the frequency and severity of acute exacerbations of asthma
TWI656880B (zh) 2012-08-21 2019-04-21 法商賽諾菲生物技術公司 投與ｉｌ－４ｒ拮抗劑以治療或預防氣喘之方法
HUE039387T2 (hu) 2012-09-07 2018-12-28 Regeneron Pharma Atópiás dermatitisz kezelési módszerei egy IL-4R antagonista adagolásával
SI3010539T1 (sl) 2013-06-21 2019-11-29 Regeneron Pharma Postopki za zdravljenje nazalne polipoze z administriranjem antagonista IL-4R
IL315136A (en) 2014-02-21 2024-10-01 Sanofi Biotechnology Methods for treating or preventing asthma by administering an il-4rantagonist
WO2016077675A1 (en) 2014-11-14 2016-05-19 Sanofi Biotechnology Methods for treating chronic sinusitis with nasal polyps by administering an il-4r antagonist
ES2969049T3 (es) * 2017-10-30 2024-05-16 Sanofi Biotechnology Antagonista de IL-4R para uso en un método para tratar o prevenir el asma
CA3194111A1 (en) 2020-10-05 2022-04-14 Christine XU Methods for treating asthma in pediatric subjects by administering an il-4r antagonist

Also Published As

Publication number Publication date
AU2020277191A1 (en) 2020-12-24
US20210322546A1 (en) 2021-10-21
RU2713406C2 (ru) 2020-02-05
EP3973987A1 (en) 2022-03-30
JP7636487B2 (ja) 2025-02-26
JP6673840B2 (ja) 2020-03-25
MX2016010854A (es) 2017-01-05
CN106232140A (zh) 2016-12-14
PL3107575T3 (pl) 2022-01-17
AU2024203849A1 (en) 2024-06-27
US10137193B2 (en) 2018-11-27
ES2897631T3 (es) 2022-03-02
JP2017507139A (ja) 2017-03-16
JP2023162343A (ja) 2023-11-08
WO2015127229A1 (en) 2015-08-27
KR20230167770A (ko) 2023-12-11
EP3973987B1 (en) 2024-01-10
IL315136A (en) 2024-10-01
HUE065844T2 (hu) 2024-06-28
EP3107575B1 (en) 2021-09-01
ES2977332T3 (es) 2024-08-22
EP4382164A2 (en) 2024-06-12
CA2940295A1 (en) 2015-08-27
AU2015218808A1 (en) 2016-09-22
US20150246119A1 (en) 2015-09-03
KR20160113733A (ko) 2016-09-30
KR20220029765A (ko) 2022-03-08
EP3107575A1 (en) 2016-12-28
RU2016136364A3 (enExample) 2018-10-11
US20190125865A1 (en) 2019-05-02
PT3107575T (pt) 2021-11-18
JP2025072593A (ja) 2025-05-09
AU2020277191B2 (en) 2024-05-16
PL3973987T3 (pl) 2024-06-24
RU2016136364A (ru) 2018-03-22
PT3973987T (pt) 2024-04-01
AU2015218808B2 (en) 2020-09-24
MX2021008113A (es) 2021-10-13
EP4382164A3 (en) 2024-08-07
KR20250154567A (ko) 2025-10-28
KR102368450B1 (ko) 2022-02-28

Similar Documents

Publication Publication Date Title
MX384192B (es) Composiciones farmaceuticas que comprenden un antagonista de il-4r para usarse en el tratamiento del asma.
EP4344706A3 (en) Methods for treating or preventing asthma by administering an il-4r antagonist
AU2018253544A1 (en) Methods for treating or preventing asthma by administering an IL-4R antagonist
ZA202004557B (en) Modulatory polynucleotides
AU2014284235B2 (en) Methods for treating nasal polyposis by administering an IL-4R antagonist
MX2023000079A (es) Composiciones farmaceuticas que comprenden un antagonista de il-4r para usarse en el tratamiento de sinusitis cronica con polipos nasales.
PH12016501966B1 (en) Compounds and compositions as toll-like receptor 7 agonists
HUE067888T2 (hu) Módszerek az allergia megelõzésére vagy kezelésére egy IL-4R antagonista adagolásával
MX2021002406A (es) Composiciones farmaceuticas que comprenden un inhibidor de il-4r para usarse en el tratamiento de la esofagitis eosinofilica.
MY187540A (en) Compounds active towards bromodomains
NZ737399A (en) Ccr2 modulators
PH12016501830A1 (en) Inhibitors of c5a for the treatment of viral pneumonia
MD20170048A2 (ro) Formulare pe bază de acetat de abirateronă şi procedee de utilizare a acesteia
MX2017003216A (es) Uso de antagonistas de il-17 para inhibir la progresion del daño estructural en pacientes con artritis psoriasica.
PH12017500348B1 (en) Tetrahydroquinoline derivatives as bromodomain inhibitors
MX2019014090A (es) Métodos para el tratamiento de la reservoritis crónica.
ZA202002480B (en) Methods for treating or preventing asthma by administering an il-4r antagonist
MX375355B (es) Una variante del factor xa para usarse en el tratamiento de la hemorragia cerebral.
HK1231767A1 (en) Methods for treating or preventing asthma by administering an il-4r antagonist
MX2019009243A (es) Antagonistas il-4r para usarse en el tratamiento o previncion de asma persistente y asma severa.
IL247290A0 (en) Methods of treating or preventing asthma by adding an il-4r antagonist
PH12014000104A1 (en) Therapeutic methods and compositions for treating diabetes
IL240241B (en) Antibodies directed to bacillus anthracis protective antigen
IL246913B (en) Methods for treating dermatitis by administering an antagonist to -il-4r
UA92304U (ru) Применение ралейкина (антагониста рецепторов интерлейкина-1) как средства противодиабетического действия для терапии инсулиннезависимого сахарного диабета