MX378293B - Metodos in vitro para correlacionar el nivel de st2 soluble y la eficiencia de terapia de ejercicio en un sujeto que tiene una enfermedad cardiovascular. - Google Patents

Metodos in vitro para correlacionar el nivel de st2 soluble y la eficiencia de terapia de ejercicio en un sujeto que tiene una enfermedad cardiovascular.

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Publication number
MX378293B
MX378293B MX2017013236A MX2017013236A MX378293B MX 378293 B MX378293 B MX 378293B MX 2017013236 A MX2017013236 A MX 2017013236A MX 2017013236 A MX2017013236 A MX 2017013236A MX 378293 B MX378293 B MX 378293B
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MX
Mexico
Prior art keywords
subject
cardiovascular disease
exercise therapy
soluble
level
Prior art date
Application number
MX2017013236A
Other languages
English (en)
Inventor
James V Snider
Robert W Gerwien
Original Assignee
Critical Care Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Critical Care Diagnostics Inc filed Critical Critical Care Diagnostics Inc
Publication of MX378293B publication Critical patent/MX378293B/es

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869—Interleukin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/715—Assays involving receptors, cell surface antigens or cell surface determinants for cytokines; for lymphokines; for interferons
    • G01N2333/7155—Assays involving receptors, cell surface antigens or cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Cardiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención se refiere a métodos para seleccionar una terapia para un sujeto que tiene una enfermedad cardiovascular, identificar un sujeto que tiene una enfermedad cardiovascular que se beneficiará o no se beneficiará de la terapia de ejercicio, determinar si un sujeto que tiene una enfermedad cardiovascular debe iniciar, continuar, no iniciar, descontinuar, o evitar la terapia de ejercicio, determinar si un sujeto que tiene una enfermedad cardiovascular debe continuar, descontinuar, o evitar la terapia de ejercicio, reducir el riesgo de un resultado adverso (por ejemplo, muerte) en un sujeto que tiene una enfermedad cardiovascular, y predecir la eficacia de terapia de ejercicio en un sujeto que tiene una enfermedad cardiovascular. Estos métodos incluyen determinar un nivel de ST2 soluble en un sujeto.
MX2017013236A 2011-07-18 2012-07-18 Metodos in vitro para correlacionar el nivel de st2 soluble y la eficiencia de terapia de ejercicio en un sujeto que tiene una enfermedad cardiovascular. MX378293B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161508923P 2011-07-18 2011-07-18
US201161509359P 2011-07-19 2011-07-19
PCT/US2012/047238 WO2013012945A1 (en) 2011-07-18 2012-07-18 Methods of treating cardiovascular diseases and predicting the efficacy of exercise therapy

Publications (1)

Publication Number Publication Date
MX378293B true MX378293B (es) 2025-03-10

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Application Number Title Priority Date Filing Date
MX2017013236A MX378293B (es) 2011-07-18 2012-07-18 Metodos in vitro para correlacionar el nivel de st2 soluble y la eficiencia de terapia de ejercicio en un sujeto que tiene una enfermedad cardiovascular.
MX2014000715A MX351428B (es) 2011-07-18 2012-07-18 Métodos in vitro para correlacionar el nivel de sr2 solubre y la eficiencia de terapia de ejercicio en un sujeto que tiene una enfermedad cardiovascular.

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MX2014000715A MX351428B (es) 2011-07-18 2012-07-18 Métodos in vitro para correlacionar el nivel de sr2 solubre y la eficiencia de terapia de ejercicio en un sujeto que tiene una enfermedad cardiovascular.

Country Status (12)

Country Link
US (5) US8748110B2 (es)
EP (2) EP3173093B1 (es)
JP (2) JP6134316B2 (es)
CN (2) CN106908604B (es)
AU (2) AU2012284039B2 (es)
BR (1) BR112014001283A2 (es)
CA (1) CA2842072A1 (es)
DK (1) DK2734222T3 (es)
ES (1) ES2611403T3 (es)
MX (2) MX378293B (es)
PL (1) PL2734222T3 (es)
WO (1) WO2013012945A1 (es)

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Publication number Publication date
JP2017194469A (ja) 2017-10-26
JP6416974B2 (ja) 2018-10-31
MX2014000715A (es) 2014-02-20
US20130071404A1 (en) 2013-03-21
MX351428B (es) 2017-10-13
US9551708B2 (en) 2017-01-24
EP2734222B1 (en) 2016-10-19
DK2734222T3 (en) 2017-01-30
EP2734222A1 (en) 2014-05-28
EP3173093B1 (en) 2018-12-05
AU2012284039A1 (en) 2014-02-06
US20210164976A1 (en) 2021-06-03
CN103796669B (zh) 2016-11-09
US20170122942A1 (en) 2017-05-04
ES2611403T3 (es) 2017-05-08
AU2012284039B2 (en) 2017-03-30
BR112014001283A2 (pt) 2017-02-21
PL2734222T3 (pl) 2017-03-31
CA2842072A1 (en) 2013-01-24
US8748110B2 (en) 2014-06-10
CN106908604B (zh) 2019-01-29
EP2734222A4 (en) 2015-04-15
AU2017204261B2 (en) 2018-09-06
JP6134316B2 (ja) 2017-05-24
JP2014529059A (ja) 2014-10-30
EP3173093A1 (en) 2017-05-31
AU2017204261A1 (en) 2017-07-13
US10928393B2 (en) 2021-02-23
US20140286944A1 (en) 2014-09-25
CN106908604A (zh) 2017-06-30
HK1198125A1 (en) 2015-03-13
US20190049444A1 (en) 2019-02-14
WO2013012945A1 (en) 2013-01-24
CN103796669A (zh) 2014-05-14

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