MX373248B - Prediccion de riesgo de evento cardiovascular y usos del mismo. - Google Patents
Prediccion de riesgo de evento cardiovascular y usos del mismo.Info
- Publication number
- MX373248B MX373248B MX2014003153A MX2014003153A MX373248B MX 373248 B MX373248 B MX 373248B MX 2014003153 A MX2014003153 A MX 2014003153A MX 2014003153 A MX2014003153 A MX 2014003153A MX 373248 B MX373248 B MX 373248B
- Authority
- MX
- Mexico
- Prior art keywords
- risk
- prediction
- biomarkers
- event
- years
- Prior art date
Links
- 230000007211 cardiovascular event Effects 0.000 title 1
- 239000000090 biomarker Substances 0.000 abstract 5
- 238000000034 method Methods 0.000 abstract 3
- 239000012472 biological sample Substances 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 238000011156 evaluation Methods 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
- G16H10/40—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/475—Assays involving growth factors
- G01N2333/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96486—Metalloendopeptidases (3.4.24)
- G01N2333/96491—Metalloendopeptidases (3.4.24) with definite EC number
- G01N2333/96494—Matrix metalloproteases, e. g. 3.4.24.7
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Medical Informatics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Primary Health Care (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Data Mining & Analysis (AREA)
- Databases & Information Systems (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Information Retrieval, Db Structures And Fs Structures Therefor (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161541828P | 2011-09-30 | 2011-09-30 | |
| PCT/US2012/058060 WO2013049674A1 (en) | 2011-09-30 | 2012-09-28 | Cardiovascular risk event prediction and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2014003153A MX2014003153A (es) | 2014-04-30 |
| MX373248B true MX373248B (es) | 2020-05-11 |
Family
ID=47993164
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014003153A MX373248B (es) | 2011-09-30 | 2012-09-28 | Prediccion de riesgo de evento cardiovascular y usos del mismo. |
| MX2020004617A MX2020004617A (es) | 2011-09-30 | 2014-03-14 | Prediccion de riesgo de evento cardiovascular y usos del mismo. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2020004617A MX2020004617A (es) | 2011-09-30 | 2014-03-14 | Prediccion de riesgo de evento cardiovascular y usos del mismo. |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US20130085079A1 (show.php) |
| EP (1) | EP2761289B1 (show.php) |
| JP (3) | JP6652781B2 (show.php) |
| KR (2) | KR102248900B1 (show.php) |
| CN (4) | CN107102151A (show.php) |
| AU (1) | AU2013202112B9 (show.php) |
| BR (2) | BR122019023720B1 (show.php) |
| CA (2) | CA3074279C (show.php) |
| ES (1) | ES2777002T3 (show.php) |
| IL (1) | IL231387A (show.php) |
| IN (1) | IN2014CN01970A (show.php) |
| MX (2) | MX373248B (show.php) |
| RU (1) | RU2651708C2 (show.php) |
| SG (3) | SG11201400904SA (show.php) |
| WO (1) | WO2013049674A1 (show.php) |
| ZA (1) | ZA201401778B (show.php) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10359425B2 (en) | 2008-09-09 | 2019-07-23 | Somalogic, Inc. | Lung cancer biomarkers and uses thereof |
| WO2012006632A2 (en) | 2010-07-09 | 2012-01-12 | Somalogic, Inc. | Lung cancer biomarkers and uses thereof |
| US20130171649A1 (en) * | 2010-06-07 | 2013-07-04 | Manuel Mayr | Methods and means for predicting or diagnosing diabetes or cardiovascular disorders based on micro rna |
| BR112013003391B8 (pt) | 2010-08-13 | 2022-10-25 | Somalogic Inc | Método para diagnosticar câncer pancreático em um indivíduo |
| KR20140015455A (ko) | 2011-03-10 | 2014-02-06 | 소마로직, 인크. | 클로스트리디움 디피실 진단을 위한 압타머 |
| JP6652781B2 (ja) * | 2011-09-30 | 2020-02-26 | ソマロジック・インコーポレーテッド | 心血管系リスクイベントの予測およびその使用 |
| CA2863035C (en) | 2012-01-27 | 2023-08-29 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for profiling and quantitating cell-free rna |
| JP6198047B2 (ja) * | 2013-08-02 | 2017-09-20 | 国立大学法人岐阜大学 | 冠動脈疾患の検査キット |
| KR102348283B1 (ko) | 2013-09-24 | 2022-01-10 | 소마로직, 인크. | 멀티앱타머 표적 검출 |
| WO2015140317A1 (en) * | 2014-03-21 | 2015-09-24 | Sanofi | New markers for the assessment of the risk for development of a cardiovascular disorder |
| SG11201608566UA (en) * | 2014-06-05 | 2016-11-29 | Sanofi Aventis Deutschland | New markers for the assessment of an increased risk for mortality |
| BR112017005730B1 (pt) * | 2014-09-26 | 2023-12-12 | Somalogic Operating Co., Inc | Método para triagem de um indivíduo quanto ao risco de um evento cardiovascular ou para predizer a probabilidade que um indivíduo tenha tal evento |
| CA3012985A1 (en) | 2015-01-27 | 2016-08-04 | Kardiatonos, Inc. | Biomarkers of vascular disease |
| WO2017011329A1 (en) * | 2015-07-10 | 2017-01-19 | West Virginia University | Markers of stroke and stroke severity |
| RU2602451C1 (ru) * | 2015-08-28 | 2016-11-20 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Красноярский государственный медицинский университет имени профессора В.Ф. Войно-Ясенецкого" Министерства здравоохранения Российской Федерации | Способ диагностики генетической предрасположенности к развитию ишемического инсульта у больных с фибрилляцией предсердий |
| KR102687249B1 (ko) | 2016-02-08 | 2024-07-22 | 소마로직 오퍼레이팅 컴퍼니, 인코포레이티드 | 비알코올성 지방간 질환 (nafld)과 비알코올성 지방간염 (nash) 생물마커 및 이들의 용도 |
| EP3426826A4 (en) * | 2016-03-09 | 2019-09-04 | Molecular Stethoscope, Inc. | METHOD AND SYSTEMS FOR DETECTING TISSUE STATES |
| CN108780101A (zh) * | 2016-04-06 | 2018-11-09 | 雀巢产品技术援助有限公司 | 用于预测体重减轻程度的生物标志物 |
| CN108882872B (zh) | 2016-04-15 | 2021-07-20 | 欧姆龙株式会社 | 生物体信息分析装置、生物体信息分析系统、程序以及生物体信息分析方法 |
| CN105907857A (zh) * | 2016-04-29 | 2016-08-31 | 天津脉络生物科技有限公司 | 一种用于动脉血栓的分子标记物和试剂及其应用 |
| WO2017214684A1 (en) * | 2016-06-17 | 2017-12-21 | Adelaide Research & Innovation Pty Ltd | Methods and products for identifying conditions associated with cardiac fibrotic remodelling |
| ES2817087T3 (es) * | 2016-08-04 | 2021-04-06 | Hoffmann La Roche | ESM-1 (endocan) circulante en la evaluación de la fibrilación auricular |
| US11079394B2 (en) * | 2017-07-25 | 2021-08-03 | Vanderbilt University | Detection of angiopoietin-2 and thrombospondin-2 in connection with diagnosing acute heart failure |
| WO2019115620A1 (en) * | 2017-12-13 | 2019-06-20 | Roche Diagnostics Gmbh | Circulating angiopoietin-2 (ang-2) and insulin-like growth factor-binding protein 7 (igfbp7) for the prediction of stroke |
| RU2685859C1 (ru) * | 2018-07-04 | 2019-04-23 | Федеральное государственное автономное образовательное учреждение высшего образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") | Способ прогнозирования риска развития ишемического инсульта |
| CN109192250B (zh) * | 2018-08-01 | 2021-12-07 | 华东理工大学 | 一种多相催化中克服表面物种快速迁移的加速模拟方法 |
| BR112021002445A2 (pt) * | 2018-08-10 | 2021-05-04 | F. Hoffmann-La Roche Ag | métodos para prever o risco de acidente vascular cerebral, para aprimorar a precisão da previsão de uma pontuação de risco clínico, para avaliar a eficácia de uma terapia, para identificar um paciente e para monitorar um paciente, usos e kit |
| US20210327540A1 (en) * | 2018-08-17 | 2021-10-21 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Use of machine learning models for prediction of clinical outcomes |
| BR112021003149A2 (pt) * | 2018-08-22 | 2021-05-11 | F. Hoffmann-La Roche Ag | métodos para avaliar a fibrilação atrial em um indivíduo, para prever o risco de acidente vascular cerebral em um indivíduo, para melhorar a precisão da previsão de uma pontuação de risco clínico de acidente vascular cerebral para um indivíduo e para auxiliar na avaliação de fibrilação atrial, método implementado por computador, kit e uso in vitro |
| US20220187312A1 (en) * | 2018-10-31 | 2022-06-16 | Centro Nacional De Investigaciones Cardiovasculares Carlos Iii (F.S.P.) | Biomarkers of subclinical atherosclerosis |
| KR102125053B1 (ko) * | 2018-12-14 | 2020-06-19 | 가톨릭대학교 산학협력단 | 심혈관계 질환의 검출용 조성물 및 이를 포함하는 키트 |
| EP3924972A4 (en) | 2019-02-14 | 2023-03-29 | Mirvie, Inc. | METHODS AND SYSTEMS FOR DETERMINING A PREGNANCY-ASsociated CONDITION OF AN INDIVIDUAL |
| GB201906052D0 (en) | 2019-04-30 | 2019-06-12 | Int Centre For Genetic Engineering And Biotechnology | Proteins with cardioprotective activity |
| US11030743B2 (en) * | 2019-05-16 | 2021-06-08 | Tencent America LLC | System and method for coronary calcium deposits detection and labeling |
| EP4025916A1 (en) * | 2019-09-03 | 2022-07-13 | SomaLogic Operating Co., Inc. | Cardiovascular risk event prediction and uses thereof |
| US20220390468A1 (en) * | 2019-11-06 | 2022-12-08 | National University Corporation Kagawa University | Heart failure marker |
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| US10902955B1 (en) | 2020-05-01 | 2021-01-26 | Georgetown University | Detecting COVID-19 using surrogates |
| CA3179456A1 (en) * | 2020-05-19 | 2021-11-25 | Henricus J. DUCKERS | Detection and treatment of conditions characterized by perfusion shortage |
| FI130424B (en) * | 2020-06-18 | 2023-08-23 | Nightingale Health Oy | Procedure for determining whether a subject has a disease or condition or whether the subject is at risk of developing a disease or condition |
| JP2023546563A (ja) * | 2020-10-20 | 2023-11-06 | ソマロジック オペレーティング カンパニー インコーポレイテッド | 心血管イベントリスクの予測 |
| RU2750716C1 (ru) * | 2020-11-23 | 2021-07-01 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр кардиологии" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ кардиологии" Минздрава России) | Способ прогнозирования сердечно-сосудистых осложнений у больных низкого или умеренного сердечно-сосудистого риска путем оценки их психологического статуса |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US5660985A (en) * | 1990-06-11 | 1997-08-26 | Nexstar Pharmaceuticals, Inc. | High affinity nucleic acid ligands containing modified nucleotides |
| US20030144476A1 (en) * | 2000-03-06 | 2003-07-31 | Pankaj Agarwal | Novel compounds |
| US20030224501A1 (en) * | 2000-03-17 | 2003-12-04 | Young Paul E. | Bone morphogenic protein polynucleotides, polypeptides, and antibodies |
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