MX370792B - Composiciones para usarse en el tratamiento de cáncer. - Google Patents
Composiciones para usarse en el tratamiento de cáncer.Info
- Publication number
- MX370792B MX370792B MX2015015518A MX2015015518A MX370792B MX 370792 B MX370792 B MX 370792B MX 2015015518 A MX2015015518 A MX 2015015518A MX 2015015518 A MX2015015518 A MX 2015015518A MX 370792 B MX370792 B MX 370792B
- Authority
- MX
- Mexico
- Prior art keywords
- cancer
- treatment
- compositions
- methods
- omomyc
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 3
- 201000011510 cancer Diseases 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 2
- 108700030515 omomyc Proteins 0.000 abstract 2
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001152—Transcription factors, e.g. SOX or c-MYC
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/09—Fusion polypeptide containing a localisation/targetting motif containing a nuclear localisation signal
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
La invención se refiere a un polipéptido que consiste en la SEQ ID NO: 1, o una variante funcionalmente equivalente del mismo, que tiene un grado de identidad con respecto a la SEQ ID NO: 1 mayor que 70%, en donde la variante funcionalmente equivalentemente es un polipéptido resultante de la inserción o de la adición de un aminoácido y/o de la eliminación de uno o más aminoácidos y/o de la sustitución conservativa de uno o más aminoácidos con respecto al polipéptido de la SEQ ID NO: 1 y en donde la variante funcionalmente equivalente del mismo puede dimerizar con Myc e inhibir su actividad una vez que se encuentra en el núcleo, siendo capaz de trastocarse a través de la membrana celular y a través de la envoltura nuclear, para usarse en medicina, en donde el polipéptido o la variante funcionalmente equivalente del mismo es para ser administrable.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP20130382167 EP2801370A1 (en) | 2013-05-07 | 2013-05-07 | Methods and compositions for the treatment of cancer |
PCT/EP2014/059315 WO2014180889A1 (en) | 2013-05-07 | 2014-05-07 | Methods and compositions for the treatment of cancer |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2015015518A MX2015015518A (es) | 2016-07-21 |
MX370792B true MX370792B (es) | 2020-01-08 |
Family
ID=48366303
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015015518A MX370792B (es) | 2013-05-07 | 2014-05-07 | Composiciones para usarse en el tratamiento de cáncer. |
Country Status (25)
Country | Link |
---|---|
US (2) | US10370434B2 (es) |
EP (4) | EP2801370A1 (es) |
JP (2) | JP6722103B2 (es) |
KR (1) | KR102324116B1 (es) |
CN (1) | CN105378084B (es) |
AU (1) | AU2014264642B2 (es) |
BR (2) | BR122020017819B1 (es) |
CA (1) | CA2911863A1 (es) |
CY (1) | CY1121849T1 (es) |
DK (1) | DK2994533T3 (es) |
EA (2) | EA035463B1 (es) |
ES (1) | ES2733515T3 (es) |
HK (2) | HK1219756A1 (es) |
HR (1) | HRP20191330T1 (es) |
HU (1) | HUE045615T2 (es) |
IL (2) | IL242483B (es) |
LT (1) | LT2994533T (es) |
ME (1) | ME03509B (es) |
MX (1) | MX370792B (es) |
PL (1) | PL2994533T3 (es) |
PT (1) | PT2994533T (es) |
RS (1) | RS59276B1 (es) |
SG (2) | SG10201709101VA (es) |
SI (1) | SI2994533T1 (es) |
WO (1) | WO2014180889A1 (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2801370A1 (en) | 2013-05-07 | 2014-11-12 | Fundació Privada Institut d'Investigació Oncològica de Vall Hebron | Methods and compositions for the treatment of cancer |
EP3411387A4 (en) | 2016-02-03 | 2019-12-04 | Kennesaw State University Research And Services Foundation Inc. | SIGNAL MOLECULES USEFUL AS CELL PENETRATION AGENTS |
WO2017190061A1 (en) * | 2016-04-29 | 2017-11-02 | The University Of Chicago | Synthetic dna binding domain peptides and uses thereof |
EP3269734A1 (en) * | 2016-07-15 | 2018-01-17 | Fundació Privada Institut d'Investigació Oncològica de Vall-Hebron | Methods and compositions for the treatment of cancer |
CN106591335A (zh) * | 2016-11-08 | 2017-04-26 | 安徽省农业科学院水稻研究所 | 一种密码子植物化改造的LbCpf1基因及其应用 |
KR20200052350A (ko) * | 2017-09-08 | 2020-05-14 | 아이디피 디스커버리 파마, 에스.엘. | 다발성 골수종의 새로운 치료 |
SG11202004861UA (en) * | 2017-11-29 | 2020-06-29 | Agency Science Tech & Res | Chimeric molecule for targeting c-myc in cells |
WO2019199803A1 (en) * | 2018-04-09 | 2019-10-17 | Board Of Regents, The University Of Texas System | Therapeutic targeting of oncogenes using exosomes |
CA3126544A1 (en) * | 2019-01-12 | 2020-07-16 | The Methodist Hospital | Self-assembled peptide nanoparticle and use thereof |
AU2020242284A1 (en) | 2019-03-19 | 2021-09-16 | Fundació Privada Institut D'investigació Oncològica De Vall Hebron | Combination therapy for the treatment of cancer |
TWI829893B (zh) * | 2019-03-19 | 2024-01-21 | 瓦爾希伯倫私人腫瘤研究基金會 | 診斷肺癌的方法 |
KR102221227B1 (ko) | 2019-05-07 | 2021-03-03 | 김영화 | 공급자 연동과 다국어 지원 기능을 구비한 쇼핑몰 플랫폼 제공 장치 및 그 방법 |
US20220307013A1 (en) * | 2019-08-30 | 2022-09-29 | The Regents Of The University Of California | Gene fragment overexpression screening methodologies, and uses thereof |
CN115925975A (zh) * | 2022-08-03 | 2023-04-07 | 山东大学 | 一种靶向肿瘤干细胞的car-mφ体内外编辑制备方法以及其应用 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4263428A (en) | 1978-03-24 | 1981-04-21 | The Regents Of The University Of California | Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same |
DE3169595D1 (en) | 1980-11-10 | 1985-05-02 | Gersonde Klaus | Method of preparing lipid vesicles by ultrasonic treatment, the use of this method and apparatus for its application |
EP0088046B1 (de) | 1982-02-17 | 1987-12-09 | Ciba-Geigy Ag | Lipide in wässriger Phase |
EP0143949B1 (en) | 1983-11-01 | 1988-10-12 | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION | Pharmaceutical composition containing urokinase |
US5322801A (en) | 1990-04-19 | 1994-06-21 | The General Hospital Corporation | Protein partner screening assays and uses thereof |
WO1993019176A1 (en) | 1992-03-23 | 1993-09-30 | Imperial Cancer Research Technology Limited | Leucine zippers |
EP1342781A1 (en) * | 2002-03-09 | 2003-09-10 | ARTEMIS Pharmaceuticals GmbH | Recombinase fusion protein with enhanced cellular uptake |
GB0413730D0 (en) * | 2004-06-18 | 2004-07-21 | Tillotts Pharma Ag | A pharmaceutical composition and its use |
US8735394B2 (en) | 2005-02-18 | 2014-05-27 | Abraxis Bioscience, Llc | Combinations and modes of administration of therapeutic agents and combination therapy |
AU2010295646B2 (en) * | 2009-09-15 | 2016-02-11 | Ellipses Pharma Limited | Treatment of cancer |
DE102009052866A1 (de) | 2009-11-13 | 2011-05-19 | Bizerba Gmbh & Co. Kg | Schneidemaschine |
EP2544686A4 (en) | 2010-02-05 | 2013-06-26 | Whitehead Biomedical Inst | COMBINED METHODS FOR THE TREATMENT OF DISEASES |
EP2579899B1 (en) * | 2010-06-14 | 2017-03-15 | F. Hoffmann-La Roche AG | Cell-penetrating peptides and uses thereof |
US9241920B2 (en) * | 2011-10-27 | 2016-01-26 | New York University | Inhibition of c-Myc ubiquitination to prevent cancer initiation and progression |
EP2801370A1 (en) | 2013-05-07 | 2014-11-12 | Fundació Privada Institut d'Investigació Oncològica de Vall Hebron | Methods and compositions for the treatment of cancer |
-
2013
- 2013-05-07 EP EP20130382167 patent/EP2801370A1/en not_active Withdrawn
-
2014
- 2014-05-07 AU AU2014264642A patent/AU2014264642B2/en active Active
- 2014-05-07 JP JP2016512358A patent/JP6722103B2/ja active Active
- 2014-05-07 HU HUE14722204A patent/HUE045615T2/hu unknown
- 2014-05-07 SG SG10201709101VA patent/SG10201709101VA/en unknown
- 2014-05-07 EA EA201690159A patent/EA035463B1/ru unknown
- 2014-05-07 EA EA202090683A patent/EA202090683A3/ru unknown
- 2014-05-07 PT PT14722204T patent/PT2994533T/pt unknown
- 2014-05-07 WO PCT/EP2014/059315 patent/WO2014180889A1/en active Application Filing
- 2014-05-07 CN CN201480032555.2A patent/CN105378084B/zh active Active
- 2014-05-07 MX MX2015015518A patent/MX370792B/es active IP Right Grant
- 2014-05-07 ES ES14722204T patent/ES2733515T3/es active Active
- 2014-05-07 DK DK14722204.6T patent/DK2994533T3/da active
- 2014-05-07 EP EP19172033.3A patent/EP3545966A1/en active Pending
- 2014-05-07 SI SI201431286T patent/SI2994533T1/sl unknown
- 2014-05-07 BR BR122020017819-1A patent/BR122020017819B1/pt active IP Right Grant
- 2014-05-07 US US14/889,656 patent/US10370434B2/en active Active
- 2014-05-07 EP EP14722204.6A patent/EP2994533B1/en active Active
- 2014-05-07 BR BR112015028115-0A patent/BR112015028115B1/pt active IP Right Grant
- 2014-05-07 CA CA2911863A patent/CA2911863A1/en active Pending
- 2014-05-07 LT LTEP14722204.6T patent/LT2994533T/lt unknown
- 2014-05-07 RS RSP20190840 patent/RS59276B1/sr unknown
- 2014-05-07 PL PL14722204T patent/PL2994533T3/pl unknown
- 2014-05-07 ME MEP-2019-203A patent/ME03509B/me unknown
- 2014-05-07 SG SG11201509131VA patent/SG11201509131VA/en unknown
- 2014-05-07 KR KR1020157034532A patent/KR102324116B1/ko active IP Right Grant
- 2014-05-07 EP EP18153052.8A patent/EP3338789A1/en active Pending
-
2015
- 2015-11-05 IL IL242483A patent/IL242483B/en active IP Right Grant
-
2016
- 2016-07-01 HK HK16107667.9A patent/HK1219756A1/zh unknown
-
2018
- 2018-08-31 HK HK18111179.0A patent/HK1251494A1/zh unknown
-
2019
- 2019-02-22 JP JP2019030931A patent/JP6790148B2/ja active Active
- 2019-06-06 US US16/433,438 patent/US11339205B2/en active Active
- 2019-07-23 HR HRP20191330TT patent/HRP20191330T1/hr unknown
- 2019-07-26 CY CY20191100800T patent/CY1121849T1/el unknown
-
2020
- 2020-03-05 IL IL273090A patent/IL273090B/en unknown
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Legal Events
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FG | Grant or registration |