DK2994533T3 - Fremgangsmåder og sammensætninger til behandling af cancer - Google Patents

Fremgangsmåder og sammensætninger til behandling af cancer Download PDF

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Publication number
DK2994533T3
DK2994533T3 DK14722204.6T DK14722204T DK2994533T3 DK 2994533 T3 DK2994533 T3 DK 2994533T3 DK 14722204 T DK14722204 T DK 14722204T DK 2994533 T3 DK2994533 T3 DK 2994533T3
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compositions
methods
treating cancer
cancer
treating
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DK14722204.6T
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Marie-Eve Beaulieu
Laura Soucek
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Fundacio Privada Inst Dinvestigacio Oncològica De Vall Hebron
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82Translation products from oncogenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001152Transcription factors, e.g. SOX or c-MYC
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/09Fusion polypeptide containing a localisation/targetting motif containing a nuclear localisation signal
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DK14722204.6T 2013-05-07 2014-05-07 Fremgangsmåder og sammensætninger til behandling af cancer DK2994533T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20130382167 EP2801370A1 (en) 2013-05-07 2013-05-07 Methods and compositions for the treatment of cancer
PCT/EP2014/059315 WO2014180889A1 (en) 2013-05-07 2014-05-07 Methods and compositions for the treatment of cancer

Publications (1)

Publication Number Publication Date
DK2994533T3 true DK2994533T3 (da) 2019-07-01

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
DK14722204.6T DK2994533T3 (da) 2013-05-07 2014-05-07 Fremgangsmåder og sammensætninger til behandling af cancer

Country Status (26)

Country Link
US (2) US10370434B2 (da)
EP (4) EP2801370A1 (da)
JP (2) JP6722103B2 (da)
KR (1) KR102324116B1 (da)
CN (1) CN105378084B (da)
AU (1) AU2014264642B2 (da)
BR (2) BR112015028115B1 (da)
CA (1) CA2911863A1 (da)
CY (1) CY1121849T1 (da)
DK (1) DK2994533T3 (da)
EA (2) EA202090683A3 (da)
ES (1) ES2733515T3 (da)
HK (1) HK1251494A1 (da)
HR (1) HRP20191330T1 (da)
HU (1) HUE045615T2 (da)
IL (2) IL242483B (da)
LT (1) LT2994533T (da)
ME (1) ME03509B (da)
MX (1) MX370792B (da)
PL (1) PL2994533T3 (da)
PT (1) PT2994533T (da)
RS (1) RS59276B1 (da)
SG (2) SG10201709101VA (da)
SI (1) SI2994533T1 (da)
SM (1) SMT201900423T1 (da)
WO (1) WO2014180889A1 (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
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EP2801370A1 (en) 2013-05-07 2014-11-12 Fundació Privada Institut d'Investigació Oncològica de Vall Hebron Methods and compositions for the treatment of cancer
US10654894B2 (en) * 2016-02-03 2020-05-19 Keenesaw State University Research And Service Foundation, Inc. Methods for delivering cargo into a cell by using signal molecules as cell penetration agents
US20190135868A1 (en) * 2016-04-29 2019-05-09 The University Of Chicago Synthetic dna binding domain peptides and uses thereof
EP3269734A1 (en) * 2016-07-15 2018-01-17 Fundació Privada Institut d'Investigació Oncològica de Vall-Hebron Methods and compositions for the treatment of cancer
CN106591335A (zh) * 2016-11-08 2017-04-26 安徽省农业科学院水稻研究所 一种密码子植物化改造的LbCpf1基因及其应用
CA3091948A1 (en) * 2017-09-08 2019-03-14 Idp Discovery Pharma, S.L. New treatments of multiple myeloma
SG11202004861UA (en) * 2017-11-29 2020-06-29 Agency Science Tech & Res Chimeric molecule for targeting c-myc in cells
JP7474702B2 (ja) 2018-03-28 2024-04-25 ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム エキソソームから単離されたdnaにおけるエピジェネティック変化の同定法
US20210024936A1 (en) * 2018-04-09 2021-01-28 Board Of Regents, The University Of Texas System Therapeutic targeting of oncogenes using exosomes
CA3126544A1 (en) * 2019-01-12 2020-07-16 The Methodist Hospital Self-assembled peptide nanoparticle and use thereof
TWI829893B (zh) * 2019-03-19 2024-01-21 瓦爾希伯倫私人腫瘤研究基金會 診斷肺癌的方法
EP3941503A1 (en) * 2019-03-19 2022-01-26 Fundació Privada Institut d'Investigació Oncològica de Vall-Hebron Combination therapy with omomyc and an antibody binding pd-1 or ctla-4 for the treatment of cancer
CN114174313A (zh) 2019-04-09 2022-03-11 芝加哥大学 采用狄尔斯-阿尔德环加成反应的通用型肽和蛋白质的大环化和多聚化
KR102221227B1 (ko) 2019-05-07 2021-03-03 김영화 공급자 연동과 다국어 지원 기능을 구비한 쇼핑몰 플랫폼 제공 장치 및 그 방법
US20220307013A1 (en) * 2019-08-30 2022-09-29 The Regents Of The University Of California Gene fragment overexpression screening methodologies, and uses thereof
CN115925975B (zh) * 2022-08-03 2024-09-17 山东大学 一种靶向肿瘤干细胞的car-mφ体内外编辑制备方法以及其应用
EP4361633A1 (en) 2022-10-25 2024-05-01 Peptomyc, S.L. Method for predicting response to a cancer treatment
EP4446742A1 (en) 2023-04-14 2024-10-16 Peptomyc, S.L. Method for assessing or monitoring the response to a cancer treatment
EP4473974A1 (en) * 2023-06-07 2024-12-11 Peptomyc, S.L. Omomyc and kras inhibitors combination therapy for the treatment of cancer
WO2025064985A1 (en) * 2023-09-22 2025-03-27 Ohio State Innovation Foundation Myc INHIBITOR PROTEINS AND USES THEREOF
CN118324872A (zh) * 2024-04-19 2024-07-12 国家纳米科学中心 靶向kras突变蛋白的多肽及其应用
CN118557561A (zh) * 2024-05-16 2024-08-30 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) 9-十六烯酸在制备防治结直肠肿瘤的产品及其作为化疗药物的增效剂中的应用

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Also Published As

Publication number Publication date
IL273090A (en) 2020-04-30
BR112015028115A2 (pt) 2017-10-17
EP3338789A1 (en) 2018-06-27
US20160122415A1 (en) 2016-05-05
EA202090683A3 (ru) 2020-09-30
KR20160013058A (ko) 2016-02-03
US11339205B2 (en) 2022-05-24
AU2014264642B2 (en) 2020-09-17
ME03509B (me) 2020-04-20
EA202090683A2 (ru) 2020-06-30
IL273090B (en) 2022-06-01
SG11201509131VA (en) 2015-12-30
JP2016520056A (ja) 2016-07-11
RS59276B1 (sr) 2019-10-31
CN105378084B (zh) 2019-07-05
CY1121849T1 (el) 2020-07-31
CN105378084A (zh) 2016-03-02
HUE045615T2 (hu) 2020-01-28
SI2994533T1 (sl) 2019-09-30
MX370792B (es) 2020-01-08
EA201690159A1 (ru) 2016-05-31
EP2801370A1 (en) 2014-11-12
WO2014180889A8 (en) 2015-06-18
KR102324116B1 (ko) 2021-11-11
CA2911863A1 (en) 2014-11-13
AU2014264642A1 (en) 2015-11-19
SG10201709101VA (en) 2017-12-28
HK1251494A1 (en) 2019-02-01
JP2019147792A (ja) 2019-09-05
PL2994533T3 (pl) 2020-03-31
EP2994533B1 (en) 2019-05-01
JP6722103B2 (ja) 2020-07-15
EP3545966A1 (en) 2019-10-02
PT2994533T (pt) 2019-08-05
EA035463B1 (ru) 2020-06-19
MX2015015518A (es) 2016-07-21
EP2994533A1 (en) 2016-03-16
US20190382468A1 (en) 2019-12-19
SMT201900423T1 (it) 2019-09-09
HRP20191330T1 (hr) 2019-10-18
JP6790148B2 (ja) 2020-11-25
US10370434B2 (en) 2019-08-06
ES2733515T3 (es) 2019-11-29
IL242483B (en) 2020-03-31
BR112015028115B1 (pt) 2023-11-21
BR122020017819B1 (pt) 2023-11-21
WO2014180889A1 (en) 2014-11-13
LT2994533T (lt) 2019-08-12
HK1219756A1 (en) 2017-04-13

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