MX368558B - Cuantificacion de alta precision de particulas sub-visibles. - Google Patents
Cuantificacion de alta precision de particulas sub-visibles.Info
- Publication number
- MX368558B MX368558B MX2017010161A MX2017010161A MX368558B MX 368558 B MX368558 B MX 368558B MX 2017010161 A MX2017010161 A MX 2017010161A MX 2017010161 A MX2017010161 A MX 2017010161A MX 368558 B MX368558 B MX 368558B
- Authority
- MX
- Mexico
- Prior art keywords
- sub
- visible particles
- pores
- filter membrane
- high precision
- Prior art date
Links
- 239000012906 subvisible particle Substances 0.000 title abstract 4
- 238000011002 quantification Methods 0.000 title abstract 2
- 239000012528 membrane Substances 0.000 abstract 4
- 239000011148 porous material Substances 0.000 abstract 4
- 239000007788 liquid Substances 0.000 abstract 3
- 239000000565 sealant Substances 0.000 abstract 3
- 238000001493 electron microscopy Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1468—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5021—Test tubes specially adapted for centrifugation purposes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/06—Investigating concentration of particle suspensions
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/06—Investigating concentration of particle suspensions
- G01N15/0606—Investigating concentration of particle suspensions by collecting particles on a support
- G01N15/0618—Investigating concentration of particle suspensions by collecting particles on a support of the filter type
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/06—Investigating concentration of particle suspensions
- G01N15/0606—Investigating concentration of particle suspensions by collecting particles on a support
- G01N15/0618—Investigating concentration of particle suspensions by collecting particles on a support of the filter type
- G01N15/0625—Optical scan of the deposits
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
- G01N2001/4088—Concentrating samples by other techniques involving separation of suspended solids filtration
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N2015/0038—Investigating nanoparticles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N2015/1486—Counting the particles
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Dispersion Chemistry (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Sampling And Sample Adjustment (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Abstract
El método es para la cuantificación de partículas sub-visibles. Se describe una membrana de filtración que tiene una pluralidad de poros que la atraviesan. La membrana de filtración está acoplada operativamente con una cámara de vacío. Los poros se sellan con un sellador. Una gota de muestra que contiene un líquido y partículas sub-visibles se aplica sobre la membrana de filtración. El líquido disuelve el sellador en los poros dispuestos directamente debajo de la gota de muestra. El líquido fluye a través de los poros en que se ha disuelto el sellador y las partículas sub-visibles permanecen sobre de la membrana de filtración. Las partículas se enumeran en un microscopio electrónico.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562269465P | 2015-12-18 | 2015-12-18 | |
| PCT/US2016/058011 WO2017105625A1 (en) | 2015-12-18 | 2016-10-21 | High precision quantification of sub-visible particles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2017010161A MX2017010161A (es) | 2017-11-17 |
| MX368558B true MX368558B (es) | 2019-10-07 |
Family
ID=59057225
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2017010161A MX368558B (es) | 2015-12-18 | 2016-10-21 | Cuantificacion de alta precision de particulas sub-visibles. |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US10247648B2 (es) |
| EP (1) | EP3389813B1 (es) |
| JP (1) | JP6621825B2 (es) |
| KR (1) | KR102150748B1 (es) |
| CN (1) | CN107106926B (es) |
| AU (1) | AU2016372660B2 (es) |
| BR (1) | BR112017022551B1 (es) |
| CA (1) | CA2964777C (es) |
| CL (1) | CL2017001694A1 (es) |
| DK (1) | DK3389813T3 (es) |
| EA (1) | EA035524B1 (es) |
| ES (1) | ES2784394T3 (es) |
| HU (1) | HUE048446T2 (es) |
| IL (1) | IL252558A0 (es) |
| MA (1) | MA41074B1 (es) |
| MX (1) | MX368558B (es) |
| MY (1) | MY188672A (es) |
| NZ (1) | NZ733989A (es) |
| PL (1) | PL3389813T3 (es) |
| PT (1) | PT3389813T (es) |
| SG (1) | SG11201706486QA (es) |
| UA (1) | UA123318C2 (es) |
| WO (1) | WO2017105625A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020041283A1 (en) * | 2018-08-21 | 2020-02-27 | Battelle Memorial Institute A Non-Profit Corporation Of The State Of Ohio | Particle sample preparation with filtration |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5385672A (en) | 1993-10-13 | 1995-01-31 | Eg&G Idaho, Inc. | Method for preparing membranes with adjustable separation performance |
| US6699665B1 (en) * | 2000-11-08 | 2004-03-02 | Surface Logix, Inc. | Multiple array system for integrating bioarrays |
| WO2002055673A1 (en) * | 2001-01-10 | 2002-07-18 | Biopore, Inc. | Cell concentrator and washer |
| US6884341B2 (en) * | 2002-10-02 | 2005-04-26 | G6 Science Corp. | Filter device to capture a desired amount of material |
| JP2005152849A (ja) | 2003-11-27 | 2005-06-16 | Kitakyushu Foundation For The Advancement Of Industry Science & Technology | 浮遊微粒子捕集用フィルタ及びそれを用いた浮遊微粒子捕集方法、浮遊微粒子分析方法、並びに浮遊微粒子捕集装置 |
| KR20070097434A (ko) * | 2004-11-12 | 2007-10-04 | 루미넥스 코포레이션 | 이미지화를 위해 마이크로스피어를 배치하는 방법 및시스템 |
| US8029744B2 (en) * | 2005-11-16 | 2011-10-04 | Hitachi, Ltd. | Method of liquid droplet formation and transport apparatus therefor and particle manipulating apparatus |
| IL173536A0 (en) | 2006-02-05 | 2006-07-05 | Ilan Avichai | Method of reversibly sealing the pores of a netting and its application to agricultural protection |
| KR101343749B1 (ko) | 2007-05-30 | 2013-12-19 | 인텔리전트 바이러스 이미징 아이엔씨. | 이미지 내 바이러스 입자를 카운팅하고 분할하기 위한 방법 |
| SE532499C2 (sv) * | 2008-01-18 | 2010-02-09 | Hemocue Ab | Metod och apparat för analys av partiklar i ett vätskeformigt prov |
| EP2260300B1 (en) * | 2008-03-07 | 2013-09-25 | Advanced Microdevices Pvt Ltd | Method and device for particle removal and droplet preparation for qualitative and quantitative bioanalysis |
| EP2335825A1 (en) * | 2009-12-21 | 2011-06-22 | F. Hoffmann-La Roche AG | Unit and device for the preparation of cells and/or particles in a liquid and method for microscopic analysis |
| US8969827B2 (en) * | 2012-07-09 | 2015-03-03 | Materials Analysis Technology (Us) Corp. | Specimen preparation for transmission electron microscopy |
| KR101371663B1 (ko) | 2012-09-03 | 2014-03-12 | 창원대학교 산학협력단 | 입자의 정량적 측정방법 및 그 장치 |
-
2016
- 2016-10-21 JP JP2017533216A patent/JP6621825B2/ja active Active
- 2016-10-21 HU HUE16876228A patent/HUE048446T2/hu unknown
- 2016-10-21 MY MYPI2018700118A patent/MY188672A/en unknown
- 2016-10-21 CA CA2964777A patent/CA2964777C/en active Active
- 2016-10-21 AU AU2016372660A patent/AU2016372660B2/en active Active
- 2016-10-21 PL PL16876228T patent/PL3389813T3/pl unknown
- 2016-10-21 MX MX2017010161A patent/MX368558B/es active IP Right Grant
- 2016-10-21 EA EA201792107A patent/EA035524B1/ru not_active IP Right Cessation
- 2016-10-21 NZ NZ733989A patent/NZ733989A/en not_active IP Right Cessation
- 2016-10-21 BR BR112017022551-4A patent/BR112017022551B1/pt not_active IP Right Cessation
- 2016-10-21 SG SG11201706486QA patent/SG11201706486QA/en unknown
- 2016-10-21 MA MA41074A patent/MA41074B1/fr unknown
- 2016-10-21 PT PT168762284T patent/PT3389813T/pt unknown
- 2016-10-21 KR KR1020177023965A patent/KR102150748B1/ko active IP Right Grant
- 2016-10-21 ES ES16876228T patent/ES2784394T3/es active Active
- 2016-10-21 DK DK16876228.4T patent/DK3389813T3/da active
- 2016-10-21 CN CN201680004052.3A patent/CN107106926B/zh active Active
- 2016-10-21 UA UAA201807032A patent/UA123318C2/uk unknown
- 2016-10-21 WO PCT/US2016/058011 patent/WO2017105625A1/en active Application Filing
- 2016-10-21 US US15/736,621 patent/US10247648B2/en active Active
- 2016-10-21 EP EP16876228.4A patent/EP3389813B1/en active Active
-
2017
- 2017-05-28 IL IL252558A patent/IL252558A0/en active IP Right Grant
- 2017-06-23 CL CL2017001694A patent/CL2017001694A1/es unknown
-
2019
- 2019-02-15 US US16/277,393 patent/US10345207B2/en active Active
- 2019-05-18 US US16/416,186 patent/US10571375B2/en active Active
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |