MX367780B - Complejo inmunogénico para vacunación y método de obtención. - Google Patents
Complejo inmunogénico para vacunación y método de obtención.Info
- Publication number
- MX367780B MX367780B MX2015014005A MX2015014005A MX367780B MX 367780 B MX367780 B MX 367780B MX 2015014005 A MX2015014005 A MX 2015014005A MX 2015014005 A MX2015014005 A MX 2015014005A MX 367780 B MX367780 B MX 367780B
- Authority
- MX
- Mexico
- Prior art keywords
- immunogenic complex
- vaccination
- production
- mannan
- dialdehyde
- Prior art date
Links
- 230000002163 immunogen Effects 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 238000002255 vaccination Methods 0.000 title 1
- ZNZYKNKBJPZETN-WELNAUFTSA-N Dialdehyde 11678 Chemical compound N1C2=CC=CC=C2C2=C1[C@H](C[C@H](/C(=C/O)C(=O)OC)[C@@H](C=C)C=O)NCC2 ZNZYKNKBJPZETN-WELNAUFTSA-N 0.000 abstract 2
- 229920000057 Mannan Polymers 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 208000035473 Communicable disease Diseases 0.000 abstract 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 230000007815 allergy Effects 0.000 abstract 1
- 230000021615 conjugation Effects 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000009826 neoplastic cell growth Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55583—Polysaccharides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
La presente invención se refiere a con un complejo inmunogénico que comprende un antígeno polimerizado, manano y un dialdehído, la composición que lo comprende, y el uso del mismo como estimulador de la respuesta inmune y vacuna, útil en el tratamiento de enfermedades infecciosas, neoplasias y alergias. Asimismo, la invención se relaciona con el método de obtención de dicho complejo inmunogénico, basado en la polimerización y conjugación simultánea del antígeno y el manano mediante el empleo de un dialdehído.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES201330474A ES2503516B1 (es) | 2013-04-03 | 2013-04-03 | Complejo inmunogénico para vacunación y método de obtención |
| PCT/ES2014/070263 WO2014162036A1 (es) | 2013-04-03 | 2014-04-03 | Complejo inmunogénico para vacunación y método de obtención |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2015014005A MX2015014005A (es) | 2016-05-05 |
| MX367780B true MX367780B (es) | 2019-09-03 |
Family
ID=50732211
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015014005A MX367780B (es) | 2013-04-03 | 2014-04-03 | Complejo inmunogénico para vacunación y método de obtención. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9901633B2 (es) |
| EP (1) | EP2982381B1 (es) |
| JP (1) | JP6285012B2 (es) |
| CN (1) | CN105492022B (es) |
| DK (1) | DK2982381T3 (es) |
| ES (2) | ES2503516B1 (es) |
| MX (1) | MX367780B (es) |
| WO (1) | WO2014162036A1 (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3046539B1 (fr) * | 2016-01-11 | 2018-01-12 | Societe Industrielle Limousine D'application Biologique | Principe actif de pichia heedii et utilisation cosmetique en particulier pour lutter contre les effets de la pollution sur la peau |
| UA128640C2 (uk) | 2019-01-17 | 2024-09-11 | Леті Фарма С.Л. | Спосіб одержання очищенного екстракту алергену |
| JP2025510729A (ja) | 2022-03-21 | 2025-04-15 | ユニバーシティ オブ サザン カリフォルニア | 三重ワクチンは、訓練免疫を介して細菌および真菌病原体に対して防御する |
| JPWO2024117232A1 (es) * | 2022-11-30 | 2024-06-06 | ||
| WO2024220928A2 (en) * | 2023-04-21 | 2024-10-24 | The Children's Medical Center Corporation | Polysaccharide adjuvants for use in protein-based or rna-based vaccines |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0892297A (ja) | 1994-09-21 | 1996-04-09 | Dai Ichi Pure Chem Co Ltd | μ−カルパイン８０ＫサブユニットのＮ末端ペプチドに対する抗体及びこれを用いる免疫測定方法及び測定試薬 |
| US8021667B2 (en) | 1994-11-16 | 2011-09-20 | Macfarlane Burnet Institute For Medical Research And Public Health Ltd | Compositions for immunotherapy and uses thereof |
| DK1409654T3 (da) | 1999-06-16 | 2008-12-08 | Boston Biomedical Res Inst | Immunologisk styring af beta-amyloid-niveauer in vivo |
| JP2004043332A (ja) | 2002-07-09 | 2004-02-12 | Nof Corp | 経口用リポソーム製剤 |
| JP4334931B2 (ja) | 2002-07-19 | 2009-09-30 | 独立行政法人科学技術振興機構 | 新規抗体酵素生産方法および新規抗体酵素 |
| MXPA05005528A (es) | 2002-11-26 | 2006-04-05 | Alk Abello As | Producto farmaceutico de alergeno. |
| WO2011140595A2 (en) | 2010-05-10 | 2011-11-17 | 4G Vaccines Pty Ltd | Immunostimulatory and vaccine compositions |
-
2013
- 2013-04-03 ES ES201330474A patent/ES2503516B1/es active Active
-
2014
- 2014-04-03 ES ES14724497T patent/ES2856690T3/es active Active
- 2014-04-03 US US14/781,733 patent/US9901633B2/en active Active
- 2014-04-03 DK DK14724497.4T patent/DK2982381T3/da active
- 2014-04-03 CN CN201480030171.7A patent/CN105492022B/zh active Active
- 2014-04-03 EP EP14724497.4A patent/EP2982381B1/en active Active
- 2014-04-03 MX MX2015014005A patent/MX367780B/es active IP Right Grant
- 2014-04-03 JP JP2016505868A patent/JP6285012B2/ja active Active
- 2014-04-03 WO PCT/ES2014/070263 patent/WO2014162036A1/es not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| ES2503516B1 (es) | 2015-09-09 |
| ES2503516R1 (es) | 2014-11-24 |
| EP2982381A1 (en) | 2016-02-10 |
| DK2982381T3 (da) | 2021-03-01 |
| US20160058859A1 (en) | 2016-03-03 |
| CN105492022B (zh) | 2020-03-10 |
| BR112015025257A2 (pt) | 2017-08-29 |
| EP2982381B1 (en) | 2020-12-02 |
| ES2856690T3 (es) | 2021-09-28 |
| MX2015014005A (es) | 2016-05-05 |
| WO2014162036A1 (es) | 2014-10-09 |
| US9901633B2 (en) | 2018-02-27 |
| CN105492022A (zh) | 2016-04-13 |
| JP6285012B2 (ja) | 2018-02-28 |
| ES2503516A2 (es) | 2014-10-06 |
| JP2016515603A (ja) | 2016-05-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |