MX365494B - Procedimiento de compuesto antifungico. - Google Patents

Procedimiento de compuesto antifungico.

Info

Publication number
MX365494B
MX365494B MX2016012056A MX2016012056A MX365494B MX 365494 B MX365494 B MX 365494B MX 2016012056 A MX2016012056 A MX 2016012056A MX 2016012056 A MX2016012056 A MX 2016012056A MX 365494 B MX365494 B MX 365494B
Authority
MX
Mexico
Prior art keywords
antifungal compound
compound process
preparing compound
useful
antifungal
Prior art date
Application number
MX2016012056A
Other languages
English (en)
Spanish (es)
Other versions
MX2016012056A (es
Inventor
J Hoekstra William
m yates Christopher
Behnke Mark
Alimardanov Asaf
A David Scott
Franklin FRY Douglas
Original Assignee
Us Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Health filed Critical Us Health
Publication of MX2016012056A publication Critical patent/MX2016012056A/es
Publication of MX365494B publication Critical patent/MX365494B/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/26Radicals substituted by halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Artificial Filaments (AREA)
MX2016012056A 2014-03-19 2015-03-19 Procedimiento de compuesto antifungico. MX365494B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461955615P 2014-03-19 2014-03-19
PCT/US2015/021491 WO2015143172A1 (en) 2014-03-19 2015-03-19 Antifungal compound process

Publications (2)

Publication Number Publication Date
MX2016012056A MX2016012056A (es) 2017-04-27
MX365494B true MX365494B (es) 2019-06-05

Family

ID=54145323

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016012056A MX365494B (es) 2014-03-19 2015-03-19 Procedimiento de compuesto antifungico.

Country Status (14)

Country Link
US (2) US10173998B2 (enExample)
EP (1) EP3119745B1 (enExample)
JP (1) JP6509897B2 (enExample)
KR (1) KR102151082B1 (enExample)
CN (2) CN106458900B (enExample)
AU (1) AU2015231226B2 (enExample)
BR (1) BR112016020937B1 (enExample)
CA (1) CA2942968C (enExample)
EA (1) EA037587B1 (enExample)
ES (1) ES2815373T3 (enExample)
HU (1) HUE052446T2 (enExample)
MX (1) MX365494B (enExample)
PL (1) PL3119745T3 (enExample)
WO (1) WO2015143172A1 (enExample)

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JP6572234B2 (ja) * 2014-03-19 2019-09-04 ヴィアメット ファーマスーティカルズ(エヌシー),インコーポレイテッド 抗真菌化合物の調製方法
AU2015231275B2 (en) 2014-03-19 2019-03-07 Mycovia Pharmaceuticals, Inc. Antifungal compound process
KR102441243B1 (ko) 2014-03-19 2022-09-07 브이피에스-3, 엘엘씨 2-(2,4-디플루오르페닐)-1,1-디플루오르-1-(5-치환된-피리딘-2-일)-3-(1h-테트라졸-1-일)프로판-2-올 및 이의 제조방법
AU2015231208B2 (en) * 2014-03-19 2019-04-04 Mycovia Pharmaceuticals, Inc. Antifungal compound process
CA2942936A1 (en) 2014-03-19 2015-09-24 Viamet Pharmaceuticals, Inc. Antifungal compound process
EP3119753B1 (en) 2014-03-19 2020-11-04 Dow AgroSciences LLC 2-(2,4-difluorophenyl)-1,1-difluoro-1-(5-substituted-pyridin-2-yl)-3-(1h-tetrazol-1-yl)propan-2-ols and processes for their preparation
WO2015143180A1 (en) 2014-03-19 2015-09-24 Viamet Pharmaceuticals, Inc. Antifungal compound process
CA2942231A1 (en) 2014-03-19 2015-09-24 Viamet Pharmaceuticals, Inc. Antifungal compound process
DK3271347T3 (da) * 2015-03-19 2022-07-18 Mycovia Pharmaceuticals Inc Antifungale forbindelser og fremstillingsfremgangsmåder
HK1263287A1 (zh) * 2015-09-18 2020-03-20 Nqp 1598, Ltd. 抗真菌化合物和制备方法
US11213031B2 (en) 2017-11-13 2022-01-04 Bayer Aktiengesellschaft Tetrazolylpropyl derivatives and their use as fungicides
AU2019325436B2 (en) * 2018-08-18 2023-10-26 5Metis, Inc. Solid forms of substituted benzoxaborole and compositions thereof
CN114573557B (zh) * 2022-03-28 2024-03-08 浙江天宇药业股份有限公司 一种奥特康唑的制备方法
CN116621816B (zh) * 2022-09-23 2025-07-04 北京莱瑞森医药科技有限公司 一种伏立康唑对映异构对b的拆分方法
CN116675672B (zh) * 2023-06-05 2025-04-25 北京康立生医药技术开发有限公司 一种抗真菌药物的制备方法
CN119798219B (zh) * 2025-01-13 2025-07-18 长治医学院 一种奥特康唑的制备方法

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Also Published As

Publication number Publication date
EP3119745A1 (en) 2017-01-25
MX2016012056A (es) 2017-04-27
HUE052446T2 (hu) 2021-04-28
JP6509897B2 (ja) 2019-05-08
WO2015143172A1 (en) 2015-09-24
CN106458900A (zh) 2017-02-22
US10392365B2 (en) 2019-08-27
CA2942968A1 (en) 2015-09-24
EP3119745A4 (en) 2017-08-23
BR112016020937B1 (pt) 2022-09-20
AU2015231226A1 (en) 2016-10-06
AU2015231226B2 (en) 2019-04-04
PL3119745T3 (pl) 2021-01-25
BR112016020937A2 (enExample) 2017-08-15
EA201691649A1 (ru) 2016-12-30
US20170088539A1 (en) 2017-03-30
US10173998B2 (en) 2019-01-08
US20190161469A1 (en) 2019-05-30
JP2017509644A (ja) 2017-04-06
CN106458900B (zh) 2019-01-01
KR102151082B1 (ko) 2020-09-03
CA2942968C (en) 2022-03-15
KR20160138012A (ko) 2016-12-02
ES2815373T3 (es) 2021-03-29
EA037587B1 (ru) 2021-04-19
EP3119745B1 (en) 2020-08-05
CN109970629A (zh) 2019-07-05
CN109970629B (zh) 2023-04-11

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