MX364003B - Tratamiento de resistencia a la insulina a traves de inhibidores del factor de transcripcion tsc22d4. - Google Patents

Tratamiento de resistencia a la insulina a traves de inhibidores del factor de transcripcion tsc22d4.

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Publication number
MX364003B
MX364003B MX2015017535A MX2015017535A MX364003B MX 364003 B MX364003 B MX 364003B MX 2015017535 A MX2015017535 A MX 2015017535A MX 2015017535 A MX2015017535 A MX 2015017535A MX 364003 B MX364003 B MX 364003B
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MX
Mexico
Prior art keywords
treatment
tsc22d4
insulin resistance
inhibitors
transcription factor
Prior art date
Application number
MX2015017535A
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English (en)
Other versions
MX2015017535A (es
Inventor
BERRIEL DIAZ Mauricio
Herzig Stephan
Friedrich Kilian
Jones Allan
Original Assignee
Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts
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Application filed by Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts filed Critical Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts
Publication of MX2015017535A publication Critical patent/MX2015017535A/es
Publication of MX364003B publication Critical patent/MX364003B/es

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Abstract

La presente invención se refiere a moduladores, en particular inhibidores, de la actividad o expresión de TSC22D4 y sus usos para la prevención, tratamiento y/o regulación de la resistencia a la insulina, síndrome metabólico y/o diabetes y/o para mejorar la sensibilidad a la insulina en mamíferos. La presente invención se refiere además a métodos de evaluación para identificar estos moduladores, el uso de moduladores como se identifica en el diagnóstico de estas enfermedades, así como kits, que comprenden los materiales para llevar a cabo los métodos de acuerdo con la presente invención.
MX2015017535A 2013-06-17 2014-06-17 Tratamiento de resistencia a la insulina a traves de inhibidores del factor de transcripcion tsc22d4. MX364003B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20130172362 EP2816356A1 (en) 2013-06-17 2013-06-17 Treatment of insulin resistance through inhibitors of transcription factor TSC22D4
PCT/EP2014/062713 WO2014202602A1 (en) 2013-06-17 2014-06-17 Treatment of insulin resistance through inhibitors of transcription factor tsc22d4

Publications (2)

Publication Number Publication Date
MX2015017535A MX2015017535A (es) 2016-08-08
MX364003B true MX364003B (es) 2019-04-10

Family

ID=48625934

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015017535A MX364003B (es) 2013-06-17 2014-06-17 Tratamiento de resistencia a la insulina a traves de inhibidores del factor de transcripcion tsc22d4.

Country Status (10)

Country Link
US (1) US9879258B2 (es)
EP (2) EP2816356A1 (es)
JP (1) JP6479780B2 (es)
KR (1) KR102401450B1 (es)
CN (1) CN105247371B (es)
CA (1) CA2908889C (es)
DK (1) DK3011341T3 (es)
ES (1) ES2733555T3 (es)
MX (1) MX364003B (es)
WO (1) WO2014202602A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3072969A1 (en) * 2015-03-23 2016-09-28 DKFZ Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts Oligonucleotide sequences targeting transcription factor TSC22D4 for the treatment of insulin resistance
CN107137701B (zh) * 2017-05-07 2020-07-14 山东兴瑞生物科技有限公司 一种提高dc疫苗抗肝癌效果的基因靶标、抑制剂和dc肿瘤疫苗
CN112956453B (zh) * 2021-04-07 2022-10-11 华北理工大学 一种黑腹果蝇胰岛素抵抗糖尿病模型的建立方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1703625A (zh) * 2002-08-06 2005-11-30 法赫马西亚及普强有限公司 果蝇g蛋白偶联受体,核酸和相关方法
JP4869942B2 (ja) * 2003-12-11 2012-02-08 ベス・イスラエル・ディーコネス・メディカル・センター，インコーポレイテッド インスリン感受性／抵抗性、糖尿病および肥満におけるｒｂｐ４
CA2554735A1 (en) * 2004-01-30 2005-08-11 Peplin Biolipids Pty Ltd Therapeutic and carrier molecules
WO2012061754A2 (en) * 2010-11-05 2012-05-10 The Broad Institute, Inc. Compounds and methods for treating autoimmune diseases
US20140227289A1 (en) * 2011-05-13 2014-08-14 Stephen Michael Cohen Compounds and methods for treating insulin resistance syndrome
CN102311952A (zh) * 2011-09-19 2012-01-11 中南大学 一种多癌风险易感性突变位点及其应用和制备的试剂盒
GB201120317D0 (en) * 2011-11-24 2012-01-04 Queen Mary & Westfield College Screening method

Also Published As

Publication number Publication date
EP3011341B1 (en) 2019-04-10
US9879258B2 (en) 2018-01-30
WO2014202602A9 (en) 2015-12-23
EP3011341A1 (en) 2016-04-27
EP2816356A1 (en) 2014-12-24
MX2015017535A (es) 2016-08-08
KR102401450B1 (ko) 2022-05-24
CA2908889A1 (en) 2014-12-24
CN105247371A (zh) 2016-01-13
JP2016532098A (ja) 2016-10-13
CA2908889C (en) 2022-07-26
JP6479780B2 (ja) 2019-03-06
ES2733555T3 (es) 2019-11-29
WO2014202602A1 (en) 2014-12-24
US20160115475A1 (en) 2016-04-28
CN105247371B (zh) 2019-01-11
KR20160021106A (ko) 2016-02-24
DK3011341T3 (da) 2019-07-22

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